𝕏

Task 56090770

Name HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1
Workunit 26637062
Created 4 Jul 2024, 20:39:09 UTC
Sent 4 Jul 2024, 21:41:51 UTC
Report deadline 7 Jul 2024, 21:41:51 UTC
Received 5 Jul 2024, 6:51:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 163832
Run time 2 hours 13 min 30 sec
CPU time 1 hours 57 min 37 sec
Validate state Valid
Credit 44.54
Device peak FLOPS 2.63 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.19 MB
Peak swap size 6.23 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1_r353426046_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1_r353426046_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.627744
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.084957
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031988
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.163813
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.663144
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031798
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11782868, states[0] = -94.208552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23836191, states[0] = -94.151981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35928920, states[0] = -94.132768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48017847, states[0] = 31.718665, states[40]= 0.003920
Saving checkpoint... 
Iteration: 58996718, states[0] = -94.125715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71698648, states[0] = -94.136011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84452207, states[0] = -94.084470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97216686, states[0] = -93.429255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110043289, states[0] = 26.029237, states[40]= 0.000231
Saving checkpoint... 
Iteration: 122654439, states[0] = -94.135960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135264889, states[0] = -93.749501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146318490, states[0] = -93.915794, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159088116, states[0] = 8.197858, states[40]= 0.002380
Saving checkpoint... 
Iteration: 171793793, states[0] = -94.136726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184510122, states[0] = -94.112130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197254090, states[0] = -93.703980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209962714, states[0] = -94.129412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222734925, states[0] = -94.137618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235318995, states[0] = -93.916787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248067690, states[0] = 17.015113, states[40]= 0.000940
Saving checkpoint... 
Iteration: 260676726, states[0] = -94.136761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273383035, states[0] = -94.024982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285993703, states[0] = -94.127505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298643882, states[0] = -94.135035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309666621, states[0] = -94.136162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322314988, states[0] = -93.906931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333365550, states[0] = -94.001719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345907792, states[0] = -94.131496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356928435, states[0] = -94.130448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369556832, states[0] = -94.123783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 380590523, states[0] = -94.129433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391562637, states[0] = -94.124826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 402327535, states[0] = -93.934860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415014352, states[0] = 31.589249, states[40]= 0.013139
Saving checkpoint... 
Iteration: 426628081, states[0] = -94.133271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435218288, states[0] = -93.470509, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447623967, states[0] = -94.132821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460310937, states[0] = -93.896294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471401754, states[0] = -94.044552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484001046, states[0] = 48.304501, states[40]= 0.336333
Saving checkpoint... 
Iteration: 494971016, states[0] = -94.127653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504644734, states[0] = -94.134093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515261436, states[0] = -93.733934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528028860, states[0] = 30.152466, states[40]= 0.000182
Saving checkpoint... 
Iteration: 540675298, states[0] = -94.135367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 553316781, states[0] = -93.910075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564317565, states[0] = -93.911866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576905849, states[0] = -94.130468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587259485, states[0] = -93.725419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599505876, states[0] = -94.108739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609455214, states[0] = -94.085310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 619565149, states[0] = -94.124194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627639797, states[0] = -94.133174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639525197, states[0] = -94.114730, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1_r353426046_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1_r353426046_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.627744
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.084957
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031988
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.163813
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.663144
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031798
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 639525197
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.114730 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 648814806, states[0] = -94.133896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658143679, states[0] = -32.485055, states[40]= 0.001576
Saving checkpoint... 
Iteration: 667491104, states[0] = -94.102775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677771783, states[0] = -94.134943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687099000, states[0] = 2.602052, states[40]= 0.003227
Saving checkpoint... 
Iteration: 697516319, states[0] = -94.111760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708493680, states[0] = -94.103620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719629182, states[0] = -94.131940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 730750437, states[0] = -94.135046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742157197, states[0] = -43.610841, states[40]= 0.000481
Saving checkpoint... 
Iteration: 754157276, states[0] = -43.677448, states[40]= 0.000477
Saving checkpoint... 
Iteration: 766204588, states[0] = -91.227518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778146943, states[0] = -35.128770, states[40]= 0.001263
Saving checkpoint... 
Iteration: 790096659, states[0] = 3.891967, states[40]= 0.003074
Saving checkpoint... 
Iteration: 802140289, states[0] = -29.752286, states[40]= 0.001845
Saving checkpoint... 
Iteration: 814339810, states[0] = -93.957210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 826414612, states[0] = -94.054870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838482085, states[0] = -94.098066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850710502, states[0] = -94.134575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862872574, states[0] = -94.130598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875037422, states[0] = 27.877086, states[40]= 0.000166
Saving checkpoint... 
Iteration: 887160955, states[0] = -46.802338, states[40]= 0.000315
Saving checkpoint... 
Iteration: 899130537, states[0] = -21.850209, states[40]= 0.001674
Saving checkpoint... 
Iteration: 911179995, states[0] = -63.468756, states[40]= 0.000024
Saving checkpoint... 
Iteration: 923238674, states[0] = -93.627932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935172956, states[0] = -57.143819, states[40]= 0.000068
Saving checkpoint... 
Iteration: 943143793, states[0] = -32.575470, states[40]= 0.001566
Saving checkpoint... 
Iteration: 955238214, states[0] = -93.625474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967352696, states[0] = -93.978947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979444733, states[0] = -94.077016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991577751, states[0] = -94.124572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1003569914, states[0] = -94.123195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016304728, states[0] = -93.877453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029032998, states[0] = 29.131937, states[40]= 0.000144
Saving checkpoint... 
Iteration: 1041745634, states[0] = -94.133593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052849523, states[0] = -94.130648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065708257, states[0] = -94.133512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078421688, states[0] = -94.059648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091276509, states[0] = -93.789271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103739808, states[0] = -94.133345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116244943, states[0] = -93.657486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128949798, states[0] = -94.125646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141618735, states[0] = -94.128982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154197798, states[0] = -84.661616, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166928046, states[0] = -94.126538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179737797, states[0] = -94.132991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192558748, states[0] = -94.120179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205333169, states[0] = -93.942492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218117034, states[0] = -10.159363, states[40]= 0.002367
Saving checkpoint... 
Iteration: 1230806490, states[0] = -94.131344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240172533, states[0] = -56.772320, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1252924067, states[0] = -94.126314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265645938, states[0] = -94.130478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277369029, states[0] = -94.002010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287807250, states[0] = -94.131043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300585157, states[0] = -94.124210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1313275986, states[0] = -93.786294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325974602, states[0] = -94.123438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338463071, states[0] = -94.086213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1351213268, states[0] = -93.270194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363106766, states[0] = -2.188383, states[40]= 0.003400


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1_r353426046_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704223722441064_ORdGradInc_k_27-Drouin_ENDO_2000-conf_102_1_r353426046_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.627744
     * GNaL_b in INaL: 0.005803
     * Gto_b in Ito: 0.084957
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031988
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.163813
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.663144
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031798
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1363106766
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -2.188383 (After loading)
 - states[40]: 0.003400 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1374376525, states[0] = -94.011529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385661692, states[0] = -94.130734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396702444, states[0] = -94.131841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1407708600, states[0] = -94.131857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418817208, states[0] = -94.130081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429957645, states[0] = -94.123791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441055976, states[0] = 21.538288, states[40]= 0.000489
Saving checkpoint... 
Iteration: 1452180971, states[0] = -64.386394, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1462876761, states[0] = -94.127503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474354927, states[0] = -93.980070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487003808, states[0] = 35.138680, states[40]= 0.504073
Saving checkpoint... 
Iteration: 1499702909, states[0] = -94.131348, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.997233
 - CaMKt in component CaMK (millimolar): 0.005743
 - cass in component intracellular_ions (millimolar): 0.000097
 - nai in component intracellular_ions (millimolar): 6.836812
 - nass in component intracellular_ions (millimolar): 6.836930
 - ki in component intracellular_ions (millimolar): 145.000692
 - kss in component intracellular_ions (millimolar): 145.000678
 - cansr in component intracellular_ions (millimolar): 1.847355
 - cajsr in component intracellular_ions (millimolar): 1.846478
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003964
 - hf in component INa (dimensionless): 0.863396
 - hs in component INa (dimensionless): 0.863398
 - j in component INa (dimensionless): 0.863411
 - hsp in component INa (dimensionless): 0.695321
 - jp in component INa (dimensionless): 0.863417
 - mL in component INaL (dimensionless): 0.000059
 - hL in component INaL (dimensionless): 0.704553
 - hLp in component INaL (dimensionless): 0.492222
 - a in component Ito (dimensionless): 0.000663
 - iF in component Ito (dimensionless): 0.999847
 - iS in component Ito (dimensionless): 0.886499
 - ap in component Ito (dimensionless): 0.000338
 - iFp in component Ito (dimensionless): 0.999847
 - iSp in component Ito (dimensionless): 0.926102
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.971391
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004566
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.110420
 - xs1 in component IKs (dimensionless): 0.135468
 - xs2 in component IKs (dimensionless): 0.000097
 - xk1 in component IK1 (dimensionless): 0.997565
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:03:22 (15856): called boinc_finish(0)

</stderr_txt>
]]>


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