𝕏

Task 56084197

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_97_1
Workunit 26634339
Created 4 Jul 2024, 18:58:24 UTC
Sent 4 Jul 2024, 20:59:25 UTC
Report deadline 7 Jul 2024, 20:59:25 UTC
Received 5 Jul 2024, 8:19:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239650
Run time 1 hours 39 min 22 sec
CPU time 1 hours 38 min 10 sec
Validate state Valid
Credit 43.88
Device peak FLOPS 4.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.84 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_97.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_97_1_r1628607580_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_97_1_r1628607580_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.255790
     * GNaL_b in INaL: 0.005781
     * Gto_b in Ito: 0.085063
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031716
     * GKs_b in IKs: 0.001926
     * GK1_b in IK1: 0.164675
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.228201
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032244
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6271965, states[0] = -84.603512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 15536118, states[0] = -82.321727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24833353, states[0] = 0.168665, states[40]= 0.000336
Saving checkpoint... 
Iteration: 34065816, states[0] = -84.581901, states[40]= 0.000001
Saving checkpoint... 
Iteration: 43438774, states[0] = -84.575929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 52708220, states[0] = -84.160160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62099566, states[0] = -84.261935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71362942, states[0] = -29.630607, states[40]= 0.000198
Saving checkpoint... 
Iteration: 80687178, states[0] = 12.952858, states[40]= 0.000071
Saving checkpoint... 
Iteration: 90201812, states[0] = -84.112257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99417932, states[0] = 22.524530, states[40]= 0.000014
Saving checkpoint... 
Iteration: 108752341, states[0] = 35.087144, states[40]= 0.876842
Saving checkpoint... 
Iteration: 117892707, states[0] = -61.639970, states[40]= 0.000006
Saving checkpoint... 
Iteration: 127018614, states[0] = -84.454651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 136562548, states[0] = 12.764666, states[40]= 0.000073
Saving checkpoint... 
Iteration: 145747859, states[0] = -84.374979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 155105968, states[0] = -84.293752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 163985438, states[0] = -26.913996, states[40]= 0.000210
Saving checkpoint... 
Iteration: 173319817, states[0] = 8.763888, states[40]= 0.000129
Saving checkpoint... 
Iteration: 182736505, states[0] = -28.050282, states[40]= 0.000207
Saving checkpoint... 
Iteration: 191928288, states[0] = -84.548137, states[40]= 0.000001
Saving checkpoint... 
Iteration: 201232606, states[0] = -84.301396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210146463, states[0] = -66.226161, states[40]= 0.000003
Saving checkpoint... 
Iteration: 219580482, states[0] = -84.135460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228954032, states[0] = -84.124963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237954781, states[0] = -84.130131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247195814, states[0] = 8.194809, states[40]= 0.000138
Saving checkpoint... 
Iteration: 256039638, states[0] = -84.514194, states[40]= 0.000001
Saving checkpoint... 
Iteration: 265217904, states[0] = -7.830569, states[40]= 0.000359
Saving checkpoint... 
Iteration: 274482659, states[0] = -84.635087, states[40]= 0.000001
Saving checkpoint... 
Iteration: 283914654, states[0] = 24.020392, states[40]= 0.000011
Saving checkpoint... 
Iteration: 292810581, states[0] = -84.561606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302181264, states[0] = -84.552470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 311576180, states[0] = -84.590057, states[40]= 0.000001
Saving checkpoint... 
Iteration: 320737020, states[0] = -28.592799, states[40]= 0.000205
Saving checkpoint... 
Iteration: 330062089, states[0] = 13.012818, states[40]= 0.000071
Saving checkpoint... 
Iteration: 339247697, states[0] = -84.370452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 348369950, states[0] = -84.647066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 357701019, states[0] = -84.588914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 366905887, states[0] = -77.877601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376287056, states[0] = -82.148252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385496157, states[0] = -84.647581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394886754, states[0] = 31.334973, states[40]= 0.032645
Saving checkpoint... 
Iteration: 404240812, states[0] = -84.641721, states[40]= 0.000001
Saving checkpoint... 
Iteration: 413554747, states[0] = -84.547099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 422576012, states[0] = -84.587675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431901788, states[0] = -84.474722, states[40]= 0.000001
Saving checkpoint... 
Iteration: 441298334, states[0] = -84.532124, states[40]= 0.000001
Saving checkpoint... 
Iteration: 450623611, states[0] = -84.372252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459976980, states[0] = -84.266132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469180183, states[0] = 16.598828, states[40]= 0.000040
Saving checkpoint... 
Iteration: 478616139, states[0] = -32.944821, states[40]= 0.000171
Saving checkpoint... 
Iteration: 488052919, states[0] = -83.883204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 497299158, states[0] = 19.583904, states[40]= 0.000023
Saving checkpoint... 
Iteration: 506464842, states[0] = -84.192791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515679714, states[0] = 16.836183, states[40]= 0.000038
Saving checkpoint... 
Iteration: 525063607, states[0] = 12.201907, states[40]= 0.000080
Saving checkpoint... 
Iteration: 534465790, states[0] = -5.789277, states[40]= 0.000368
Saving checkpoint... 
Iteration: 543713948, states[0] = -84.605626, states[40]= 0.000001
Saving checkpoint... 
Iteration: 553010247, states[0] = -84.416759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 562236395, states[0] = -27.920754, states[40]= 0.000207
Saving checkpoint... 
Iteration: 571610845, states[0] = -27.334197, states[40]= 0.000209
Saving checkpoint... 
Iteration: 580828345, states[0] = -84.588563, states[40]= 0.000001
Saving checkpoint... 
Iteration: 590061642, states[0] = -83.980460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599088549, states[0] = -84.182673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608439401, states[0] = -84.004185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617812833, states[0] = -83.990495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626999766, states[0] = -84.646565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 636421437, states[0] = 20.890864, states[40]= 0.000018
Saving checkpoint... 
Iteration: 645640897, states[0] = -84.435277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 655133430, states[0] = 30.383366, states[40]= 0.106200
Saving checkpoint... 
Iteration: 664494797, states[0] = -84.640956, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673413653, states[0] = -84.503681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682794279, states[0] = -84.517811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 692148873, states[0] = -84.460750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 701624428, states[0] = -84.644835, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710905036, states[0] = -84.479078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719672655, states[0] = 20.310223, states[40]= 0.000020
Saving checkpoint... 
Iteration: 728970083, states[0] = -84.610714, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738377059, states[0] = 35.813735, states[40]= 0.947913
Saving checkpoint... 
Iteration: 747778153, states[0] = 28.748256, states[40]= 0.000102
Saving checkpoint... 
Iteration: 757064250, states[0] = -84.560073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766421488, states[0] = -84.521581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775658588, states[0] = -80.218154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784831779, states[0] = -84.590230, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794251461, states[0] = 36.744954, states[40]= 0.937852
Saving checkpoint... 
Iteration: 803506275, states[0] = -84.396836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812863788, states[0] = -84.320578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821858582, states[0] = -84.294456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831279593, states[0] = -84.475488, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840616762, states[0] = -84.334152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849785605, states[0] = 25.793523, states[40]= 0.000014
Saving checkpoint... 
Iteration: 859124243, states[0] = -84.641690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 868510894, states[0] = 31.141802, states[40]= 0.044304
Saving checkpoint... 
Iteration: 877847720, states[0] = -84.611411, states[40]= 0.000001
Saving checkpoint... 
Iteration: 886840970, states[0] = -84.602044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 895913985, states[0] = 24.323189, states[40]= 0.000011
Saving checkpoint... 
Iteration: 905090042, states[0] = -84.186330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914360963, states[0] = -27.450158, states[40]= 0.000209
Saving checkpoint... 
Iteration: 923781598, states[0] = -78.540289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933037993, states[0] = 24.761522, states[40]= 0.000011
Saving checkpoint... 
Iteration: 942403143, states[0] = 28.753331, states[40]= 0.000102
Saving checkpoint... 
Iteration: 951671967, states[0] = -84.519207, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961258339, states[0] = -51.079085, states[40]= 0.000026
Saving checkpoint... 
Iteration: 970498992, states[0] = -84.639350, states[40]= 0.000001
Saving checkpoint... 
Iteration: 979841215, states[0] = -84.600634, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989071945, states[0] = -84.057461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998465415, states[0] = -84.186891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1007889429, states[0] = -84.423216, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1017243963, states[0] = -84.340876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1026628136, states[0] = -84.380071, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035759778, states[0] = 30.826186, states[40]= 0.065846
Saving checkpoint... 
Iteration: 1045229152, states[0] = -20.064698, states[40]= 0.000216
Saving checkpoint... 
Iteration: 1054710636, states[0] = -84.154631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063893866, states[0] = 31.341393, states[40]= 0.002618
Saving checkpoint... 
Iteration: 1073379306, states[0] = -46.763857, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1082131944, states[0] = -84.394101, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1091557983, states[0] = -84.541128, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097576659, states[0] = -84.575996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1106843870, states[0] = -84.206316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111894589, states[0] = 31.215048, states[40]= 0.002027
Saving checkpoint... 
Iteration: 1121297022, states[0] = 20.616043, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1127238972, states[0] = -84.626119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1133116952, states[0] = -84.329411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137385282, states[0] = 30.977443, states[40]= 0.055056
Saving checkpoint... 
Iteration: 1141846951, states[0] = -84.605416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1146318354, states[0] = -84.560464, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152346768, states[0] = -84.604976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1158252344, states[0] = -84.374319, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161020099, states[0] = 31.115887, states[40]= 0.001693
Saving checkpoint... 
Iteration: 1166296627, states[0] = 20.804574, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1169154334, states[0] = -84.468290, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1174723862, states[0] = -84.234651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180980858, states[0] = -21.936700, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1183960241, states[0] = -1.115818, states[40]= 0.000329
Saving checkpoint... 
Iteration: 1188316792, states[0] = -84.556758, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1191151625, states[0] = -72.819962, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1195805901, states[0] = -84.534750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1198683867, states[0] = -83.942219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201546859, states[0] = 20.694380, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1207406228, states[0] = -84.473078, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1210093469, states[0] = -84.599430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1214647614, states[0] = 30.519445, states[40]= 0.000697
Saving checkpoint... 
Iteration: 1218983789, states[0] = -84.287862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1224824203, states[0] = 6.218016, states[40]= 0.000175
Saving checkpoint... 
Iteration: 1234013509, states[0] = -84.415624, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1239827141, states[0] = 4.421429, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1247412253, states[0] = -82.189453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253694150, states[0] = 9.153560, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1263056169, states[0] = 16.104424, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1272378652, states[0] = 31.864709, states[40]= 0.565211
Saving checkpoint... 
Iteration: 1278303860, states[0] = -84.528763, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1287679291, states[0] = -84.529528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1293736225, states[0] = -84.619948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1299784234, states[0] = 26.374135, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1306127536, states[0] = 34.535157, states[40]= 0.824189
Saving checkpoint... 
Iteration: 1312377339, states[0] = -84.371343, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1318562288, states[0] = 12.915464, states[40]= 0.000072
Saving checkpoint... 
Iteration: 1324825753, states[0] = -84.570172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1328821529, states[0] = -84.047604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337954461, states[0] = -84.576067, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1343735641, states[0] = -27.094147, states[40]= 0.000209
Saving checkpoint... 
Iteration: 1351318323, states[0] = -84.021913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354398068, states[0] = -84.445571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1360461088, states[0] = -84.585978, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1363556233, states[0] = 16.072611, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1368145807, states[0] = -65.337005, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1374219624, states[0] = -84.205722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377000637, states[0] = 31.448167, states[40]= 0.098590
Saving checkpoint... 
Iteration: 1382891507, states[0] = -84.423300, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390484627, states[0] = -84.616315, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1396738027, states[0] = -84.305643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404078996, states[0] = 3.243683, states[40]= 0.000239
Saving checkpoint... 
Iteration: 1411258344, states[0] = -51.068058, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1420618624, states[0] = -35.527845, states[40]= 0.000143
Saving checkpoint... 
Iteration: 1429351379, states[0] = -84.244041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438805713, states[0] = -84.529738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1448055626, states[0] = -83.901692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457508256, states[0] = -84.391954, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1466862378, states[0] = -84.301114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475970968, states[0] = -84.597801, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1485109778, states[0] = -26.167244, states[40]= 0.000211
Saving checkpoint... 
Iteration: 1494296180, states[0] = -84.507018, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.506181
 - CaMKt in component CaMK (millimolar): 0.029856
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.757244
 - nass in component intracellular_ions (millimolar): 6.757386
 - ki in component intracellular_ions (millimolar): 144.952856
 - kss in component intracellular_ions (millimolar): 144.952829
 - cansr in component intracellular_ions (millimolar): 1.951039
 - cajsr in component intracellular_ions (millimolar): 1.784720
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.010303
 - hf in component INa (dimensionless): 0.570602
 - hs in component INa (dimensionless): 0.570499
 - j in component INa (dimensionless): 0.569946
 - hsp in component INa (dimensionless): 0.323925
 - jp in component INa (dimensionless): 0.569533
 - mL in component INaL (dimensionless): 0.000357
 - hL in component INaL (dimensionless): 0.361398
 - hLp in component INaL (dimensionless): 0.160994
 - a in component Ito (dimensionless): 0.001257
 - iF in component Ito (dimensionless): 0.999195
 - iS in component Ito (dimensionless): 0.416424
 - ap in component Ito (dimensionless): 0.000640
 - iFp in component Ito (dimensionless): 0.999195
 - iSp in component Ito (dimensionless): 0.453153
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.863860
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.997982
 - jca in component ICaL (dimensionless): 0.999314
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004894
 - xrf in component IKr (dimensionless): 0.000103
 - xrs in component IKr (dimensionless): 0.628679
 - xs1 in component IKs (dimensionless): 0.355261
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996799
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
04:04:21 (197992): called boinc_finish(0)

</stderr_txt>
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