𝕏

Task 56078698

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192_1
Workunit 26631591
Created 4 Jul 2024, 18:55:48 UTC
Sent 4 Jul 2024, 20:32:41 UTC
Report deadline 7 Jul 2024, 20:32:41 UTC
Received 5 Jul 2024, 7:29:52 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222286
Run time 2 hours 40 min 29 sec
CPU time 2 hours 3 min 11 sec
Validate state Valid
Credit 43.47
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.79 MB
Peak swap size 32.63 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192_1_r1439499060_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192_1_r1439499060_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.270913
     * GNaL_b in INaL: 0.005863
     * Gto_b in Ito: 0.085304
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031789
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163661
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.220394
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033206
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 16646292, states[0] = -58.344809, states[40]= 0.000009
Saving checkpoint... 
Iteration: 31800526, states[0] = -84.313245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49552065, states[0] = 19.196259, states[40]= 0.000036
Saving checkpoint... 
Iteration: 65644380, states[0] = -53.745527, states[40]= 0.000019
Saving checkpoint... 
Iteration: 82538342, states[0] = 25.215960, states[40]= 0.000015
Saving checkpoint... 
Iteration: 99230653, states[0] = -84.003239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114990326, states[0] = -84.491075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 132026274, states[0] = 29.583769, states[40]= 0.000193
Saving checkpoint... 
Iteration: 147732945, states[0] = -84.012283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164207445, states[0] = -83.850936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179325283, states[0] = -84.334182, states[40]= 0.000001
Saving checkpoint... 
Iteration: 193834990, states[0] = -84.352260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 208776046, states[0] = -84.202529, states[40]= 0.000001
Saving checkpoint... 
Iteration: 223550611, states[0] = 20.029317, states[40]= 0.000034
Saving checkpoint... 
Iteration: 238107692, states[0] = -16.248038, states[40]= 0.000301
Saving checkpoint... 
Iteration: 252996470, states[0] = -84.488844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 267054116, states[0] = 18.442938, states[40]= 0.000044
Saving checkpoint... 
Iteration: 282399999, states[0] = -84.434770, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298137705, states[0] = -46.374574, states[40]= 0.000051
Saving checkpoint... 
Iteration: 312514792, states[0] = 31.495977, states[40]= 0.010770
Saving checkpoint... 
Iteration: 325159263, states[0] = -69.910499, states[40]= 0.000002
Saving checkpoint... 
Iteration: 340834691, states[0] = -84.349580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 356518164, states[0] = 31.356702, states[40]= 0.003277
Saving checkpoint... 
Iteration: 371948639, states[0] = -84.467510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 387839903, states[0] = -84.358094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401943519, states[0] = -84.464324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411992505, states[0] = -84.485486, states[40]= 0.000001
Saving checkpoint... 
Iteration: 427974558, states[0] = -84.478781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444788394, states[0] = -84.239232, states[40]= 0.000001
Saving checkpoint... 
Iteration: 461867552, states[0] = -84.397798, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478221174, states[0] = -83.937330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494174146, states[0] = -82.515294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 510382326, states[0] = -84.414423, states[40]= 0.000001
Saving checkpoint... 
Iteration: 526782255, states[0] = -84.218979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542290859, states[0] = -84.245281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558997501, states[0] = -84.485168, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574806577, states[0] = -84.287123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 585745555, states[0] = -84.071299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 596878199, states[0] = -84.408748, states[40]= 0.000001
Saving checkpoint... 
Iteration: 607871743, states[0] = -84.401073, states[40]= 0.000001
Saving checkpoint... 
Iteration: 620151137, states[0] = -60.322438, states[40]= 0.000007
Saving checkpoint... 
Iteration: 631484918, states[0] = -84.480058, states[40]= 0.000001
Saving checkpoint... 
Iteration: 642269532, states[0] = -84.173219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653203086, states[0] = -83.812435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664974386, states[0] = -84.475644, states[40]= 0.000001
Saving checkpoint... 
Iteration: 676490308, states[0] = -84.481337, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688701709, states[0] = -83.801738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699784795, states[0] = -84.224794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 710365002, states[0] = -84.391298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 721286474, states[0] = -84.229736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733919019, states[0] = -84.444281, states[40]= 0.000001
Saving checkpoint... 
Iteration: 745646695, states[0] = -55.542601, states[40]= 0.000015
Saving checkpoint... 
Iteration: 756747254, states[0] = -84.077229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767674262, states[0] = -82.538830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778248647, states[0] = -84.083560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789136766, states[0] = -45.422673, states[40]= 0.000058
Saving checkpoint... 
Iteration: 801318419, states[0] = -84.311443, states[40]= 0.000001
Saving checkpoint... 
Iteration: 812236070, states[0] = -84.019588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823835159, states[0] = -84.344110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 834773909, states[0] = -84.186617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845550330, states[0] = 20.159091, states[40]= 0.000033
Saving checkpoint... 
Iteration: 856599539, states[0] = -8.005516, states[40]= 0.000453
Saving checkpoint... 
Iteration: 868579329, states[0] = 5.945213, states[40]= 0.000246
Saving checkpoint... 
Iteration: 880223421, states[0] = -83.945835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891421046, states[0] = -84.443702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 904230936, states[0] = -83.989902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917847109, states[0] = -84.362977, states[40]= 0.000001
Saving checkpoint... 
Iteration: 931179332, states[0] = -83.323598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942222024, states[0] = -83.936391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955330515, states[0] = -84.333846, states[40]= 0.000001
Saving checkpoint... 
Iteration: 967338341, states[0] = -84.347844, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978484029, states[0] = -84.475249, states[40]= 0.000001
Saving checkpoint... 
Iteration: 990677414, states[0] = -83.121026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1001537869, states[0] = 25.463816, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1012577397, states[0] = 6.991410, states[40]= 0.000219
Saving checkpoint... 
Iteration: 1023202038, states[0] = -83.799666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035001946, states[0] = 35.731634, states[40]= 0.924215
Saving checkpoint... 
Iteration: 1046496424, states[0] = -84.478525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1057255575, states[0] = -84.111298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068059545, states[0] = 15.921574, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1078871120, states[0] = -84.394188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1089175470, states[0] = -82.805140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105468962, states[0] = -84.467699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1121085473, states[0] = 2.435431, states[40]= 0.000344
Saving checkpoint... 
Iteration: 1137848247, states[0] = -84.361888, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1154024854, states[0] = 30.004974, states[40]= 0.000315
Saving checkpoint... 
Iteration: 1167071643, states[0] = 9.992865, states[40]= 0.000152
Saving checkpoint... 
Iteration: 1177825062, states[0] = -84.320328, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1189092435, states[0] = -2.137225, states[40]= 0.000450
Saving checkpoint... 
Iteration: 1202041409, states[0] = 24.019845, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1213130438, states[0] = -39.131406, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1224243798, states[0] = -84.054140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235389515, states[0] = -84.412461, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1246334446, states[0] = -84.337305, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1257041983, states[0] = 23.780504, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1267588931, states[0] = 0.272726, states[40]= 0.000401
Saving checkpoint... 
Iteration: 1278936424, states[0] = -84.448813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1290502366, states[0] = 34.607455, states[40]= 0.829355
Saving checkpoint... 
Iteration: 1302891342, states[0] = -84.413392, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1313831368, states[0] = -84.330762, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1325357856, states[0] = -84.373642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336341689, states[0] = -84.348722, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192_1_r1439499060_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_1000-conf_192_1_r1439499060_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.270913
     * GNaL_b in INaL: 0.005863
     * Gto_b in Ito: 0.085304
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031789
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163661
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.220394
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033206
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1336341689
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.348722 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1352347347, states[0] = -84.357683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1371469343, states[0] = -84.464416, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1390103773, states[0] = -12.147438, states[40]= 0.000378
Saving checkpoint... 
Iteration: 1408848824, states[0] = -84.359248, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1425514829, states[0] = 31.502053, states[40]= 0.010628
Saving checkpoint... 
Iteration: 1443580017, states[0] = 5.571854, states[40]= 0.000256
Saving checkpoint... 
Iteration: 1461192280, states[0] = -83.711056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1479006968, states[0] = 29.728165, states[40]= 0.170460
Saving checkpoint... 
Iteration: 1495340139, states[0] = -84.344034, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.349625
 - CaMKt in component CaMK (millimolar): 0.016746
 - cass in component intracellular_ions (millimolar): 0.000091
 - nai in component intracellular_ions (millimolar): 6.609918
 - nass in component intracellular_ions (millimolar): 6.610037
 - ki in component intracellular_ions (millimolar): 145.176231
 - kss in component intracellular_ions (millimolar): 145.176208
 - cansr in component intracellular_ions (millimolar): 1.795378
 - cajsr in component intracellular_ions (millimolar): 1.740848
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.010466
 - hf in component INa (dimensionless): 0.564288
 - hs in component INa (dimensionless): 0.564255
 - j in component INa (dimensionless): 0.564083
 - hsp in component INa (dimensionless): 0.318521
 - jp in component INa (dimensionless): 0.563961
 - mL in component INaL (dimensionless): 0.000368
 - hL in component INaL (dimensionless): 0.382956
 - hLp in component INaL (dimensionless): 0.181668
 - a in component Ito (dimensionless): 0.001270
 - iF in component Ito (dimensionless): 0.999173
 - iS in component Ito (dimensionless): 0.549259
 - ap in component Ito (dimensionless): 0.000647
 - iFp in component Ito (dimensionless): 0.999173
 - iSp in component Ito (dimensionless): 0.589486
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.907958
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999802
 - jca in component ICaL (dimensionless): 0.999970
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003521
 - xrf in component IKr (dimensionless): 0.000014
 - xrs in component IKr (dimensionless): 0.507452
 - xs1 in component IKs (dimensionless): 0.281667
 - xs2 in component IKs (dimensionless): 0.000286
 - xk1 in component IK1 (dimensionless): 0.996836
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:29:43 (1292): called boinc_finish(0)

</stderr_txt>
]]>


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