𝕏

Task 56078668

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_500-conf_692_1
Workunit 26631576
Created 4 Jul 2024, 18:55:48 UTC
Sent 4 Jul 2024, 20:32:51 UTC
Report deadline 7 Jul 2024, 20:32:51 UTC
Received 5 Jul 2024, 13:43:57 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237908
Run time 2 hours 53 min 22 sec
CPU time 1 hours 16 min 44 sec
Validate state Valid
Credit 45.78
Device peak FLOPS 1.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.60 MB
Peak swap size 5.11 MB
Peak disk usage 0.17 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_500-conf_692.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_500-conf_692_1_r450030033_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_500-conf_692_1_r450030033_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.376020
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.083735
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031904
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162918
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.192430
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033070
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 6000.000000
     * CL_0 in membrane: 500.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1499750000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10137886, states[0] = -87.221688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20026409, states[0] = 18.063752, states[40]= 0.007534
Saving checkpoint... 
Iteration: 30160942, states[0] = -87.280683, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40524042, states[0] = 19.264516, states[40]= 0.008071
Saving checkpoint... 
Iteration: 50187917, states[0] = -87.334478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59312731, states[0] = -4.347160, states[40]= 0.004136
Saving checkpoint... 
Iteration: 68548217, states[0] = 6.645122, states[40]= 0.005708
Saving checkpoint... 
Iteration: 76816937, states[0] = -8.528683, states[40]= 0.003121
Saving checkpoint... 
Iteration: 85757714, states[0] = 24.641918, states[40]= 0.076900
Saving checkpoint... 
Iteration: 95491518, states[0] = -87.413257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104991802, states[0] = -87.412853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114830737, states[0] = -24.950248, states[40]= 0.000705
Saving checkpoint... 
Iteration: 125115964, states[0] = -70.444106, states[40]= 0.000001
Saving checkpoint... 
Iteration: 135143773, states[0] = -87.183349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 145121164, states[0] = -78.565030, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154863014, states[0] = -65.874431, states[40]= 0.000002
Saving checkpoint... 
Iteration: 164445245, states[0] = -87.337462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174323704, states[0] = -16.295651, states[40]= 0.001522
Saving checkpoint... 
Iteration: 183904181, states[0] = -87.232588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193857068, states[0] = -57.504018, states[40]= 0.000009
Saving checkpoint... 
Iteration: 202915336, states[0] = -87.265607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212045331, states[0] = 8.511648, states[40]= 0.005847
Saving checkpoint... 
Iteration: 221507351, states[0] = 24.888817, states[40]= 0.083038
Saving checkpoint... 
Iteration: 231032249, states[0] = 15.696327, states[40]= 0.006647
Saving checkpoint... 
Iteration: 240759740, states[0] = 23.773178, states[40]= 0.049116
Saving checkpoint... 
Iteration: 250619746, states[0] = -76.391898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260944402, states[0] = -87.335382, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271308439, states[0] = -0.408170, states[40]= 0.004908
Saving checkpoint... 
Iteration: 281332409, states[0] = -26.928779, states[40]= 0.000595
Saving checkpoint... 
Iteration: 290741387, states[0] = -87.410210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 300598380, states[0] = -46.330132, states[40]= 0.000051
Saving checkpoint... 
Iteration: 309485586, states[0] = -87.402962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 318731907, states[0] = -87.398115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328072258, states[0] = -14.532302, states[40]= 0.001809
Saving checkpoint... 
Iteration: 338217400, states[0] = -87.376917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 348373165, states[0] = -81.221917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358310872, states[0] = -2.435900, states[40]= 0.004540
Saving checkpoint... 
Iteration: 367136186, states[0] = -87.000217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376525784, states[0] = 18.687296, states[40]= 0.007615
Saving checkpoint... 
Iteration: 385851935, states[0] = -50.812461, states[40]= 0.000026
Saving checkpoint... 
Iteration: 395110796, states[0] = -62.627098, states[40]= 0.000004
Saving checkpoint... 
Iteration: 404265870, states[0] = 22.175353, states[40]= 0.015617
Saving checkpoint... 
Iteration: 413589636, states[0] = -35.655297, states[40]= 0.000232
Saving checkpoint... 
Iteration: 423126935, states[0] = -84.697298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432726168, states[0] = -87.390037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442470518, states[0] = -87.381662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451247132, states[0] = -87.416747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460676134, states[0] = -87.293694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470423242, states[0] = -87.286364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480348991, states[0] = -47.093171, states[40]= 0.000046
Saving checkpoint... 
Iteration: 490126154, states[0] = -84.156861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500024532, states[0] = 19.209673, states[40]= 0.007940
Saving checkpoint... 
Iteration: 509228896, states[0] = -87.393808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518047128, states[0] = 7.418768, states[40]= 0.005763
Saving checkpoint... 
Iteration: 527227166, states[0] = -87.391363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536435063, states[0] = -87.314897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545110533, states[0] = -62.253952, states[40]= 0.000004
Saving checkpoint... 
Iteration: 555076042, states[0] = -19.150022, states[40]= 0.001160
Saving checkpoint... 
Iteration: 565085572, states[0] = -30.757979, states[40]= 0.000411
Saving checkpoint... 
Iteration: 574685195, states[0] = -87.315158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 584487669, states[0] = -87.405331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593782352, states[0] = 15.645609, states[40]= 0.006637
Saving checkpoint... 
Iteration: 603841397, states[0] = -37.778232, states[40]= 0.000176
Saving checkpoint... 
Iteration: 613831827, states[0] = -26.220867, states[40]= 0.000633
Saving checkpoint... 
Iteration: 624043469, states[0] = 9.616392, states[40]= 0.005933
Saving checkpoint... 
Iteration: 634078465, states[0] = -22.119381, states[40]= 0.000893
Saving checkpoint... 
Iteration: 643569941, states[0] = -11.771841, states[40]= 0.002357
Saving checkpoint... 
Iteration: 653462936, states[0] = -87.369341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 663433517, states[0] = -87.311224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673631910, states[0] = -86.544648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683614549, states[0] = -68.174055, states[40]= 0.000002
Saving checkpoint... 
Iteration: 693654103, states[0] = -87.231670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703522576, states[0] = 19.982594, states[40]= 0.008630
Saving checkpoint... 
Iteration: 713339951, states[0] = -36.034292, states[40]= 0.000221
Saving checkpoint... 
Iteration: 723166503, states[0] = -87.268218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 733058280, states[0] = -0.280999, states[40]= 0.004929
Saving checkpoint... 
Iteration: 742894893, states[0] = -87.190648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752863257, states[0] = -66.213678, states[40]= 0.000002
Saving checkpoint... 
Iteration: 762698732, states[0] = -87.343542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772433575, states[0] = -87.311247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782336877, states[0] = -32.331903, states[40]= 0.000346
Saving checkpoint... 
Iteration: 792180914, states[0] = -87.304994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802021420, states[0] = 20.412845, states[40]= 0.009191
Saving checkpoint... 
Iteration: 811590744, states[0] = -36.989947, states[40]= 0.000195
Saving checkpoint... 
Iteration: 821311492, states[0] = -2.981729, states[40]= 0.004429
Saving checkpoint... 
Iteration: 830958698, states[0] = -87.361924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840808383, states[0] = -0.362891, states[40]= 0.004915
Saving checkpoint... 
Iteration: 849950315, states[0] = -87.346524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859931241, states[0] = -87.305700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869915006, states[0] = -87.263934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879302040, states[0] = 4.259142, states[40]= 0.005498
Saving checkpoint... 
Iteration: 887918659, states[0] = -87.273900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 897166332, states[0] = -87.267571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906613096, states[0] = -65.972754, states[40]= 0.000002
Saving checkpoint... 
Iteration: 915985249, states[0] = -87.401910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924703996, states[0] = -87.353381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 933562717, states[0] = -4.099709, states[40]= 0.004187
Saving checkpoint... 
Iteration: 942791448, states[0] = 10.783039, states[40]= 0.006029
Saving checkpoint... 
Iteration: 951974339, states[0] = -87.386861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961437447, states[0] = -87.319815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970831958, states[0] = -26.379630, states[40]= 0.000624
Saving checkpoint... 
Iteration: 980658812, states[0] = -87.246011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990801246, states[0] = 4.789489, states[40]= 0.005547
Saving checkpoint... 
Iteration: 1000220080, states[0] = -87.380425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010190701, states[0] = -87.326850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019680893, states[0] = -87.304712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027948145, states[0] = -87.342120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1037316215, states[0] = -7.593847, states[40]= 0.003350
Saving checkpoint... 
Iteration: 1046842781, states[0] = -39.451805, states[40]= 0.000140
Saving checkpoint... 
Iteration: 1056496631, states[0] = -87.415567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066059347, states[0] = -1.143876, states[40]= 0.004783
Saving checkpoint... 
Iteration: 1075431785, states[0] = -87.306764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085181138, states[0] = -87.305226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1095170562, states[0] = -87.278752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1105045883, states[0] = 8.179947, states[40]= 0.005821
Saving checkpoint... 
Iteration: 1114480749, states[0] = -87.395742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124000484, states[0] = -4.141928, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1132946027, states[0] = -87.337790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140916484, states[0] = -87.267739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150239584, states[0] = -87.407139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159767187, states[0] = 21.803684, states[40]= 0.013200
Saving checkpoint... 
Iteration: 1169153959, states[0] = -87.230710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178166131, states[0] = -87.266731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187997292, states[0] = -87.416182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197617639, states[0] = -73.043324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1206953148, states[0] = -87.351522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215857769, states[0] = -58.438385, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1223861644, states[0] = -63.840271, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1232969925, states[0] = -87.379950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242253395, states[0] = 32.110458, states[40]= 0.132866
Saving checkpoint... 
Iteration: 1251703739, states[0] = -87.352574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261415542, states[0] = -87.265021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270438434, states[0] = -87.321675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279986152, states[0] = -87.402702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289418218, states[0] = -87.272303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298644505, states[0] = -87.187217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308349347, states[0] = -47.537866, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1317708679, states[0] = -87.361396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327539221, states[0] = 12.032358, states[40]= 0.006144
Saving checkpoint... 
Iteration: 1337371548, states[0] = -79.082003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346942101, states[0] = -87.329479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356544602, states[0] = 8.948555, states[40]= 0.005880
Saving checkpoint... 
Iteration: 1366259500, states[0] = 23.853862, states[40]= 0.051794
Saving checkpoint... 
Iteration: 1376025025, states[0] = 19.006793, states[40]= 0.007804
Saving checkpoint... 
Iteration: 1385778621, states[0] = 17.431878, states[40]= 0.007085
Saving checkpoint... 
Iteration: 1395715929, states[0] = -87.373492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405411235, states[0] = -87.252690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414903517, states[0] = -87.228994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424968952, states[0] = -87.378249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434945827, states[0] = -87.337079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444946169, states[0] = -87.337759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454838466, states[0] = -34.244944, states[40]= 0.000277
Saving checkpoint... 
Iteration: 1464839088, states[0] = -34.993841, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1474800924, states[0] = 5.002450, states[40]= 0.005566
Saving checkpoint... 
Iteration: 1485042065, states[0] = 10.430555, states[40]= 0.005999
Saving checkpoint... 
Iteration: 1494968661, states[0] = -87.377724, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -87.294626
 - CaMKt in component CaMK (millimolar): 0.019322
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 6.749795
 - nass in component intracellular_ions (millimolar): 6.749895
 - ki in component intracellular_ions (millimolar): 145.207915
 - kss in component intracellular_ions (millimolar): 145.207889
 - cansr in component intracellular_ions (millimolar): 1.423539
 - cajsr in component intracellular_ions (millimolar): 1.206558
 - cai in component intracellular_ions (millimolar): 0.000093
 - m in component INa (dimensionless): 0.007787
 - hf in component INa (dimensionless): 0.677541
 - hs in component INa (dimensionless): 0.677440
 - j in component INa (dimensionless): 0.676745
 - hsp in component INa (dimensionless): 0.431009
 - jp in component INa (dimensionless): 0.674815
 - mL in component INaL (dimensionless): 0.000210
 - hL in component INaL (dimensionless): 0.387039
 - hLp in component INaL (dimensionless): 0.181380
 - a in component Ito (dimensionless): 0.001041
 - iF in component Ito (dimensionless): 0.999506
 - iS in component Ito (dimensionless): 0.293493
 - ap in component Ito (dimensionless): 0.000531
 - iFp in component Ito (dimensionless): 0.999506
 - iSp in component Ito (dimensionless): 0.341177
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.857753
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.991066
 - jca in component ICaL (dimensionless): 0.991423
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004183
 - xrf in component IKr (dimensionless): 0.001742
 - xrs in component IKr (dimensionless): 0.673737
 - xs1 in component IKs (dimensionless): 0.383008
 - xs2 in component IKs (dimensionless): 0.000214
 - xk1 in component IK1 (dimensionless): 0.996911
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:43:28 (12284): called boinc_finish(0)

</stderr_txt>
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