𝕏

Task 56078638

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192_1
Workunit 26631561
Created 4 Jul 2024, 18:55:48 UTC
Sent 4 Jul 2024, 20:32:41 UTC
Report deadline 7 Jul 2024, 20:32:41 UTC
Received 5 Jul 2024, 10:32:42 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222286
Run time 2 hours 19 min 12 sec
CPU time 2 hours 10 min 27 sec
Validate state Valid
Credit 40.69
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 2.30 MB
Peak swap size 32.63 GB
Peak disk usage 1.25 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192_1_r136850256_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192_1_r136850256_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.270913
     * GNaL_b in INaL: 0.005863
     * Gto_b in Ito: 0.085304
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031789
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163661
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.220394
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033206
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192_1_r136850256_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Pieske_4000-conf_192_1_r136850256_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.270913
     * GNaL_b in INaL: 0.005863
     * Gto_b in Ito: 0.085304
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031789
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163661
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.220394
     * GKb_b in IKb: 0.003805
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033206
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 5.400000
     * nao in extracellular: 152.000000
Starting output configuration...
Output starts at iteration 1498000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 4610720, states[0] = -86.818100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21298943, states[0] = -86.684514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37766433, states[0] = -86.608057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54063643, states[0] = 11.462053, states[40]= 0.004242
Saving checkpoint... 
Iteration: 70523301, states[0] = -86.541735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85658392, states[0] = -86.526351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101825178, states[0] = -86.514056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117206861, states[0] = -86.514766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132777814, states[0] = -86.516926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146877993, states[0] = -86.513062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160049590, states[0] = 16.296167, states[40]= 0.004176
Saving checkpoint... 
Iteration: 172972561, states[0] = -86.508095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186100027, states[0] = -2.020563, states[40]= 0.003390
Saving checkpoint... 
Iteration: 200552197, states[0] = -86.500567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215735444, states[0] = -86.494221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231212493, states[0] = -86.500637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 247219168, states[0] = -86.500208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262773447, states[0] = -86.507234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277655885, states[0] = -86.493874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293457027, states[0] = -86.496076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309176041, states[0] = -86.500461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324586283, states[0] = -86.501758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340321566, states[0] = -86.412441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355910400, states[0] = -86.491438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371141466, states[0] = -86.500974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386977369, states[0] = -86.504108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401738015, states[0] = -86.492765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417116939, states[0] = -86.501407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432509934, states[0] = -86.492985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443186580, states[0] = -86.500098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454082075, states[0] = 6.231977, states[40]= 0.004084
Saving checkpoint... 
Iteration: 467950707, states[0] = -86.491095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 482059828, states[0] = 13.590971, states[40]= 0.004203
Saving checkpoint... 
Iteration: 497410737, states[0] = -86.496452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513227744, states[0] = -86.499345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528830596, states[0] = -86.506351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545113261, states[0] = -86.501442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561209935, states[0] = -86.499649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576885569, states[0] = -86.505630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 592397796, states[0] = -86.461625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608180204, states[0] = -71.258296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 623841462, states[0] = -86.491845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639701898, states[0] = -86.493034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655380109, states[0] = -86.496861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671297600, states[0] = -86.498134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687528680, states[0] = -86.494874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703618024, states[0] = -86.493861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718592239, states[0] = -86.502017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734332659, states[0] = -86.421803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750163753, states[0] = -53.598712, states[40]= 0.000014
Saving checkpoint... 
Iteration: 766036425, states[0] = 19.467762, states[40]= 0.004431
Saving checkpoint... 
Iteration: 781586662, states[0] = -86.494186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796811711, states[0] = -86.506475, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812424200, states[0] = -86.472043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828550082, states[0] = -86.498247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843988474, states[0] = -86.490776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 859968068, states[0] = -86.490903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875512407, states[0] = -86.495036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891260950, states[0] = -86.498699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 906536264, states[0] = -86.496619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920380074, states[0] = -86.452983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935510358, states[0] = -86.495049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 950723574, states[0] = -86.506508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966502961, states[0] = -86.491722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981675952, states[0] = -86.493217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997673212, states[0] = -86.493241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010611314, states[0] = -86.503181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026777411, states[0] = -86.506626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041941601, states[0] = -86.491043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056694725, states[0] = -86.506114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072049838, states[0] = 16.295267, states[40]= 0.004174
Saving checkpoint... 
Iteration: 1087857483, states[0] = -86.491633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103289177, states[0] = -86.498188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119034449, states[0] = -86.502853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134447308, states[0] = -86.479286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149874032, states[0] = -86.491498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165354554, states[0] = -86.497144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180898656, states[0] = -86.505312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196578943, states[0] = -86.500913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1212537514, states[0] = -86.496715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228285080, states[0] = -86.373204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1244402701, states[0] = -86.463638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259684470, states[0] = -86.493081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275799887, states[0] = -86.492050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291450503, states[0] = -86.495751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1307436633, states[0] = -86.495935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323247209, states[0] = -86.498851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339618007, states[0] = -86.493739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355188563, states[0] = -86.499881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370317152, states[0] = -86.408109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385931881, states[0] = -86.491042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401794684, states[0] = -86.492069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1416978104, states[0] = -86.503873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430824452, states[0] = -86.506240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443010550, states[0] = -86.503252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458041869, states[0] = 18.255414, states[40]= 0.004246
Saving checkpoint... 
Iteration: 1473063271, states[0] = -86.502226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488394292, states[0] = -86.459865, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.366547
 - CaMKt in component CaMK (millimolar): 0.000891
 - cass in component intracellular_ions (millimolar): 0.000069
 - nai in component intracellular_ions (millimolar): 6.055773
 - nass in component intracellular_ions (millimolar): 6.055818
 - ki in component intracellular_ions (millimolar): 145.940174
 - kss in component intracellular_ions (millimolar): 145.940163
 - cansr in component intracellular_ions (millimolar): 1.249750
 - cajsr in component intracellular_ions (millimolar): 1.249898
 - cai in component intracellular_ions (millimolar): 0.000071
 - m in component INa (dimensionless): 0.008549
 - hf in component INa (dimensionless): 0.643359
 - hs in component INa (dimensionless): 0.643360
 - j in component INa (dimensionless): 0.643362
 - hsp in component INa (dimensionless): 0.394425
 - jp in component INa (dimensionless): 0.643364
 - mL in component INaL (dimensionless): 0.000251
 - hL in component INaL (dimensionless): 0.462719
 - hLp in component INaL (dimensionless): 0.273153
 - a in component Ito (dimensionless): 0.001108
 - iF in component Ito (dimensionless): 0.999419
 - iS in component Ito (dimensionless): 0.985457
 - ap in component Ito (dimensionless): 0.000565
 - iFp in component Ito (dimensionless): 0.999419
 - iSp in component Ito (dimensionless): 0.991578
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997461
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001265
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.020508
 - xs1 in component IKs (dimensionless): 0.037591
 - xs2 in component IKs (dimensionless): 0.000228
 - xk1 in component IK1 (dimensionless): 0.997133
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:32:29 (1215): called boinc_finish(0)

</stderr_txt>
]]>