𝕏

Task 56078127

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692_0
Workunit 26631306
Created 4 Jul 2024, 18:55:32 UTC
Sent 4 Jul 2024, 20:32:41 UTC
Report deadline 7 Jul 2024, 20:32:41 UTC
Received 5 Jul 2024, 7:29:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 222286
Run time 2 hours 39 min 24 sec
CPU time 2 hours 2 min 12 sec
Validate state Valid
Credit 44.12
Device peak FLOPS 5.11 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.78 MB
Peak swap size 32.63 GB
Peak disk usage 0.34 MB

Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692_0_r762018090_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692_0_r762018090_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.376020
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.083735
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031904
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162918
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.192430
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033070
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 16351357, states[0] = -94.899513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31076138, states[0] = 5.197180, states[40]= 0.004620
Saving checkpoint... 
Iteration: 49010672, states[0] = 27.745812, states[40]= 0.039148
Saving checkpoint... 
Iteration: 65005337, states[0] = 30.389316, states[40]= 0.231129
Saving checkpoint... 
Iteration: 82037426, states[0] = 22.112707, states[40]= 0.001952
Saving checkpoint... 
Iteration: 98631308, states[0] = -43.129485, states[40]= 0.000242
Saving checkpoint... 
Iteration: 115154900, states[0] = -69.115031, states[40]= 0.000004
Saving checkpoint... 
Iteration: 131903764, states[0] = -94.889317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148306872, states[0] = -94.800363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 164349769, states[0] = -94.850408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180834639, states[0] = -94.835069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195195725, states[0] = -94.486396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209819568, states[0] = -94.817152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224630432, states[0] = -42.166223, states[40]= 0.000275
Saving checkpoint... 
Iteration: 239025674, states[0] = 25.826192, states[40]= 0.001639
Saving checkpoint... 
Iteration: 253544583, states[0] = 19.521740, states[40]= 0.002423
Saving checkpoint... 
Iteration: 267766582, states[0] = -94.725898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 283520484, states[0] = 26.983184, states[40]= 0.002587
Saving checkpoint... 
Iteration: 298723549, states[0] = -94.601391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 313136056, states[0] = -47.924899, states[40]= 0.000124
Saving checkpoint... 
Iteration: 326013432, states[0] = 27.729033, states[40]= 0.015961
Saving checkpoint... 
Iteration: 341822872, states[0] = -94.820707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357456356, states[0] = -94.909684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372939549, states[0] = -94.903880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388770465, states[0] = -94.734005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403833312, states[0] = -94.832609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414085557, states[0] = -0.308318, states[40]= 0.004512
Saving checkpoint... 
Iteration: 429315993, states[0] = -94.811588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445595144, states[0] = -7.975760, states[40]= 0.003133
Saving checkpoint... 
Iteration: 462444579, states[0] = -94.905348, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479463824, states[0] = -94.911449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495556916, states[0] = 14.629895, states[40]= 0.003397
Saving checkpoint... 
Iteration: 512262008, states[0] = -94.714294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528322908, states[0] = -94.820007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544216815, states[0] = -94.575313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560838646, states[0] = -94.837695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576653318, states[0] = -67.014812, states[40]= 0.000006
Saving checkpoint... 
Iteration: 588681641, states[0] = -94.299217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599924862, states[0] = -94.897089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610978265, states[0] = -94.914812, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623282899, states[0] = -94.758257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634723928, states[0] = -94.601397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645604335, states[0] = -16.877627, states[40]= 0.001514
Saving checkpoint... 
Iteration: 656615969, states[0] = -28.140370, states[40]= 0.001083
Saving checkpoint... 
Iteration: 668491096, states[0] = -94.917574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680242284, states[0] = -94.661178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692311441, states[0] = -94.804372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703797563, states[0] = -94.783555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714834402, states[0] = -94.832563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725869107, states[0] = -94.864237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738430434, states[0] = -94.898878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749904838, states[0] = -94.886911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761130934, states[0] = -42.667224, states[40]= 0.000258
Saving checkpoint... 
Iteration: 771894010, states[0] = -94.880773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782642040, states[0] = -54.243956, states[40]= 0.000048
Saving checkpoint... 
Iteration: 793291387, states[0] = -94.772904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805487279, states[0] = -94.916183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816638060, states[0] = -50.021389, states[40]= 0.000091
Saving checkpoint... 
Iteration: 828285323, states[0] = -94.761960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839098293, states[0] = -10.932232, states[40]= 0.002470
Saving checkpoint... 
Iteration: 850236375, states[0] = -94.642451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861318846, states[0] = -94.813581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873197032, states[0] = -94.490016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 885159746, states[0] = -75.930270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 896565586, states[0] = 10.813886, states[40]= 0.004068
Saving checkpoint... 
Iteration: 909488050, states[0] = -94.915945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 922949756, states[0] = -94.905301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936734742, states[0] = -94.636912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 947730734, states[0] = -94.623735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 960378535, states[0] = -94.870137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972844833, states[0] = -94.842294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984322888, states[0] = -94.818166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996661207, states[0] = -78.239301, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007451542, states[0] = -94.905559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018885104, states[0] = -94.874292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029696106, states[0] = -94.484844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041381487, states[0] = -94.871823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053173608, states[0] = -93.054366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063868608, states[0] = -94.862513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075007462, states[0] = 28.345030, states[40]= 0.114147
Saving checkpoint... 
Iteration: 1085798175, states[0] = -94.783013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096419327, states[0] = -94.892660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111785470, states[0] = -94.761098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127395921, states[0] = -94.880477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144045570, states[0] = 19.149158, states[40]= 0.002495
Saving checkpoint... 
Iteration: 1160919418, states[0] = -94.892445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174461058, states[0] = -94.907878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185415712, states[0] = -94.890625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196401279, states[0] = -94.883221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209747740, states[0] = -94.674716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220926386, states[0] = -94.895277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232236502, states[0] = -94.641317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243616076, states[0] = -28.240298, states[40]= 0.001079
Saving checkpoint... 
Iteration: 1254755013, states[0] = -94.694009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265596976, states[0] = -9.674041, states[40]= 0.002745
Saving checkpoint... 
Iteration: 1276740071, states[0] = -94.652160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287562498, states[0] = 12.219590, states[40]= 0.003842
Saving checkpoint... 
Iteration: 1299535717, states[0] = 22.735314, states[40]= 0.001870
Saving checkpoint... 
Iteration: 1311703102, states[0] = -94.515960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323106460, states[0] = -18.971982, states[40]= 0.001346
Saving checkpoint... 
Iteration: 1334657351, states[0] = -72.370851, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1345858695, states[0] = -94.853418, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692_0_r762018090_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_692_0_r762018090_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.376020
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.083735
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031904
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.162918
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.192430
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033070
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1345858695
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.853418 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1362969159, states[0] = -94.909448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381614307, states[0] = -26.552253, states[40]= 0.001145
Saving checkpoint... 
Iteration: 1400113731, states[0] = -26.002157, states[40]= 0.001161
Saving checkpoint... 
Iteration: 1419042879, states[0] = 20.162098, states[40]= 0.002304
Saving checkpoint... 
Iteration: 1436722646, states[0] = -94.593538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454004194, states[0] = 33.145497, states[40]= 0.331165
Saving checkpoint... 
Iteration: 1471477737, states[0] = -94.911267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489095480, states[0] = -8.279701, states[40]= 0.003063
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.791998
 - CaMKt in component CaMK (millimolar): 0.012754
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.746624
 - nass in component intracellular_ions (millimolar): 6.746722
 - ki in component intracellular_ions (millimolar): 145.133468
 - kss in component intracellular_ions (millimolar): 145.133446
 - cansr in component intracellular_ions (millimolar): 1.671324
 - cajsr in component intracellular_ions (millimolar): 1.629737
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003659
 - hf in component INa (dimensionless): 0.878082
 - hs in component INa (dimensionless): 0.878074
 - j in component INa (dimensionless): 0.878022
 - hsp in component INa (dimensionless): 0.722204
 - jp in component INa (dimensionless): 0.877987
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704542
 - hLp in component INaL (dimensionless): 0.441922
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.611957
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.682889
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916522
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999836
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003086
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.365351
 - xs1 in component IKs (dimensionless): 0.266469
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997366
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
09:28:49 (1294): called boinc_finish(0)

</stderr_txt>
]]>


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