Task 56078121

Name	HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392_0
Workunit	26631303
Created	4 Jul 2024, 18:55:32 UTC
Sent	4 Jul 2024, 20:32:41 UTC
Report deadline	7 Jul 2024, 20:32:41 UTC
Received	5 Jul 2024, 10:31:38 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	222286
Run time	2 hours 19 min 7 sec
CPU time	2 hours 10 min 18 sec
Validate state	Valid
Credit	42.82
Device peak FLOPS	5.11 GFLOPS
Application version	Human ventricular cell models optimization v0.02 x86_64-apple-darwin
Peak working set size	1.92 MB
Peak swap size	32.63 GB
Peak disk usage	0.34 MB
Stderr output

<core_client_version>7.24.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392_0_r575627105_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392_0_r575627105_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.296103
     * GNaL_b in INaL: 0.005807
     * Gto_b in Ito: 0.084845
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031798
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163056
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.543958
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032276
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392_0_r575627105_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Coppini_1000-conf_392_0_r575627105_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.296103
     * GNaL_b in INaL: 0.005807
     * Gto_b in Ito: 0.084845
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031798
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.163056
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.543958
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032276
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 3000.000000
     * CL_0 in membrane: 1000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 4646578, states[0] = -66.735849, states[40]= 0.000003
Saving checkpoint... 
Iteration: 22009943, states[0] = 27.599813, states[40]= 0.048898
Saving checkpoint... 
Iteration: 37544306, states[0] = 19.512329, states[40]= 0.002375
Saving checkpoint... 
Iteration: 53446130, states[0] = -94.916049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69815327, states[0] = -94.817584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85842902, states[0] = -94.848067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101835369, states[0] = -94.839308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117623389, states[0] = -35.007712, states[40]= 0.000650
Saving checkpoint... 
Iteration: 133522077, states[0] = 26.638068, states[40]= 0.002037
Saving checkpoint... 
Iteration: 148762882, states[0] = -94.719488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162800757, states[0] = -94.792666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175686062, states[0] = -94.408455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188655607, states[0] = -69.492698, states[40]= 0.000004
Saving checkpoint... 
Iteration: 201531954, states[0] = 23.986960, states[40]= 0.001659
Saving checkpoint... 
Iteration: 216763175, states[0] = -94.719611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232234546, states[0] = -94.640097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248274551, states[0] = -94.744691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264182267, states[0] = -94.313064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 279710230, states[0] = -94.550805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294920651, states[0] = -94.898593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310395409, states[0] = -94.885516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 325532930, states[0] = 23.674015, states[40]= 0.001698
Saving checkpoint... 
Iteration: 341404788, states[0] = -94.890617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 356915253, states[0] = -94.895830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372467212, states[0] = -94.915055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388151025, states[0] = -63.804552, states[40]= 0.000010
Saving checkpoint... 
Iteration: 403963622, states[0] = -94.913901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419402043, states[0] = -94.888825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435731525, states[0] = -94.629331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450248981, states[0] = -94.682345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455104777, states[0] = -17.079103, states[40]= 0.001492
Saving checkpoint... 
Iteration: 466016188, states[0] = 27.510054, states[40]= 0.006934
Saving checkpoint... 
Iteration: 478885381, states[0] = -94.878671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492067349, states[0] = 10.053596, states[40]= 0.004144
Saving checkpoint... 
Iteration: 508284370, states[0] = -94.763002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523586509, states[0] = -0.838074, states[40]= 0.004443
Saving checkpoint... 
Iteration: 538804142, states[0] = -94.796127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554755079, states[0] = -94.698206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571236140, states[0] = -94.643797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587230777, states[0] = -94.626212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602930958, states[0] = -94.901783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618770545, states[0] = -94.734650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 634173928, states[0] = -93.040272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 649908487, states[0] = -94.891308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665658867, states[0] = -74.037291, states[40]= 0.000002
Saving checkpoint... 
Iteration: 680940495, states[0] = -94.905175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696607978, states[0] = -20.218346, states[40]= 0.001286
Saving checkpoint... 
Iteration: 712278016, states[0] = -94.749879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728131260, states[0] = -42.678691, states[40]= 0.000259
Saving checkpoint... 
Iteration: 744147912, states[0] = -60.251789, states[40]= 0.000018
Saving checkpoint... 
Iteration: 759955667, states[0] = -94.910057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 775246621, states[0] = -94.674428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791015547, states[0] = 27.558758, states[40]= 0.008345
Saving checkpoint... 
Iteration: 806883214, states[0] = -94.875938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822897050, states[0] = -94.884409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 838921995, states[0] = -94.897012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854530525, states[0] = 24.435119, states[40]= 0.001612
Saving checkpoint... 
Iteration: 870144167, states[0] = -56.154989, states[40]= 0.000035
Saving checkpoint... 
Iteration: 885584227, states[0] = 0.720231, states[40]= 0.004577
Saving checkpoint... 
Iteration: 901419947, states[0] = -94.895838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917290280, states[0] = -94.772050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931638353, states[0] = -49.978227, states[40]= 0.000092
Saving checkpoint... 
Iteration: 945453563, states[0] = -94.908640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 961412357, states[0] = -94.892002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977218875, states[0] = -94.582094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993099152, states[0] = -11.545639, states[40]= 0.002338
Saving checkpoint... 
Iteration: 1009009339, states[0] = 27.756512, states[40]= 0.061121
Saving checkpoint... 
Iteration: 1022285049, states[0] = -94.762193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038034118, states[0] = 23.284294, states[40]= 0.001750
Saving checkpoint... 
Iteration: 1053516822, states[0] = 27.453485, states[40]= 0.005814
Saving checkpoint... 
Iteration: 1068909102, states[0] = -94.889943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084748006, states[0] = -94.677069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1100470542, states[0] = -94.913059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116126915, states[0] = -38.373173, states[40]= 0.000446
Saving checkpoint... 
Iteration: 1131792798, states[0] = -94.775538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147368459, states[0] = -94.864042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163233200, states[0] = -94.631914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178263835, states[0] = -94.717232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193649083, states[0] = -61.563958, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1209011717, states[0] = 27.673381, states[40]= 0.027794
Saving checkpoint... 
Iteration: 1224506849, states[0] = 28.546006, states[40]= 0.140532
Saving checkpoint... 
Iteration: 1239913580, states[0] = -94.891484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255637700, states[0] = -49.292435, states[40]= 0.000102
Saving checkpoint... 
Iteration: 1271424772, states[0] = -94.896502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287382373, states[0] = -94.873452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303221622, states[0] = -94.591042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318972210, states[0] = -94.912633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334605392, states[0] = -17.682251, states[40]= 0.001438
Saving checkpoint... 
Iteration: 1350649714, states[0] = -62.280876, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1366374709, states[0] = -94.867818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1382172032, states[0] = -92.094195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1397714528, states[0] = -94.563561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413564319, states[0] = 11.461107, states[40]= 0.003932
Saving checkpoint... 
Iteration: 1429171335, states[0] = -91.627110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443699121, states[0] = -94.497819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456029159, states[0] = 24.846843, states[40]= 0.001580
Saving checkpoint... 
Iteration: 1470628487, states[0] = -39.914476, states[40]= 0.000370
Saving checkpoint... 
Iteration: 1486064317, states[0] = 11.462124, states[40]= 0.003932
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.794207
 - CaMKt in component CaMK (millimolar): 0.012790
 - cass in component intracellular_ions (millimolar): 0.000088
 - nai in component intracellular_ions (millimolar): 6.737561
 - nass in component intracellular_ions (millimolar): 6.737658
 - ki in component intracellular_ions (millimolar): 145.141877
 - kss in component intracellular_ions (millimolar): 145.141856
 - cansr in component intracellular_ions (millimolar): 1.673081
 - cajsr in component intracellular_ions (millimolar): 1.631435
 - cai in component intracellular_ions (millimolar): 0.000090
 - m in component INa (dimensionless): 0.003658
 - hf in component INa (dimensionless): 0.878120
 - hs in component INa (dimensionless): 0.878112
 - j in component INa (dimensionless): 0.878061
 - hsp in component INa (dimensionless): 0.722276
 - jp in component INa (dimensionless): 0.878026
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.704501
 - hLp in component INaL (dimensionless): 0.441710
 - a in component Ito (dimensionless): 0.000628
 - iF in component Ito (dimensionless): 0.999867
 - iS in component Ito (dimensionless): 0.611610
 - ap in component Ito (dimensionless): 0.000320
 - iFp in component Ito (dimensionless): 0.999867
 - iSp in component Ito (dimensionless): 0.682507
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.916339
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999835
 - jca in component ICaL (dimensionless): 0.999973
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003095
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.365401
 - xs1 in component IKs (dimensionless): 0.266945
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997366
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:31:22 (1205): called boinc_finish(0)

</stderr_txt>
]]>