𝕏

Task 56076146

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_ENDO_4000-conf_590_1
Workunit 26630315
Created 4 Jul 2024, 18:54:35 UTC
Sent 4 Jul 2024, 20:24:03 UTC
Report deadline 7 Jul 2024, 20:24:03 UTC
Received 5 Jul 2024, 23:04:39 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 214494
Run time 2 hours 41 min 24 sec
CPU time 2 hours 18 min 5 sec
Validate state Valid
Credit 45.47
Device peak FLOPS 3.15 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.61 MB
Peak swap size 6.24 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_ENDO_4000-conf_590.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_ENDO_4000-conf_590_1_r254305578_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_ENDO_4000-conf_590_1_r254305578_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.870299
     * GNaL_b in INaL: 0.005855
     * Gto_b in Ito: 0.083644
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031744
     * GKs_b in IKs: 0.001930
     * GK1_b in IK1: 0.164421
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.314932
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033907
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 750.000000
     * CL_0 in membrane: 4000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 7842467, states[0] = -94.139707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 16160735, states[0] = -43.168497, states[40]= 0.000412
Saving checkpoint... 
Iteration: 24412567, states[0] = -93.950230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 32056300, states[0] = 22.386325, states[40]= 0.000633
Saving checkpoint... 
Iteration: 39888268, states[0] = -93.982424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48185448, states[0] = -59.617138, states[40]= 0.000050
Saving checkpoint... 
Iteration: 56189959, states[0] = -63.261497, states[40]= 0.000028
Saving checkpoint... 
Iteration: 64849717, states[0] = -94.001407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73545905, states[0] = -93.976977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81756733, states[0] = -93.971617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90347809, states[0] = -93.809661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98796827, states[0] = -94.000210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 106865878, states[0] = -93.998662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115150492, states[0] = -93.988021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123382589, states[0] = -93.979910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131791173, states[0] = -93.969776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140453774, states[0] = -93.935540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149265470, states[0] = -93.983500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157955105, states[0] = -93.966672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167016454, states[0] = -93.992804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175567982, states[0] = -93.974402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 183712910, states[0] = -93.971040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191990372, states[0] = -93.965954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200414593, states[0] = -93.902514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 208520642, states[0] = -93.969262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216854606, states[0] = -93.998196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224947865, states[0] = -93.995199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233720639, states[0] = -93.970713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241714469, states[0] = -93.970820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250288379, states[0] = -93.652214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259281108, states[0] = -93.982552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267825752, states[0] = -93.968543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276554537, states[0] = -93.979524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284733291, states[0] = -93.998960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291371966, states[0] = -93.979514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298329086, states[0] = -93.768615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306770990, states[0] = -93.999195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314243445, states[0] = -93.461026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322874121, states[0] = -93.997391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331336410, states[0] = -93.980541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339530788, states[0] = -93.974881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347894895, states[0] = -93.967104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357107885, states[0] = -93.988671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365657841, states[0] = -93.971746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 373749349, states[0] = -93.969771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381813637, states[0] = -93.968492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 389670791, states[0] = -93.971399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398229048, states[0] = -93.320314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406977387, states[0] = -93.993645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415264722, states[0] = -93.982735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423809356, states[0] = -93.968473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432877693, states[0] = -93.997024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441654718, states[0] = -93.971634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 450329660, states[0] = -93.769572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458715346, states[0] = -93.998131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466934039, states[0] = -93.995100, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474837610, states[0] = -93.997958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 483306650, states[0] = -93.981150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 491885624, states[0] = -93.966920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499955938, states[0] = -93.965717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508388774, states[0] = -93.872394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516500968, states[0] = -93.960630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524771066, states[0] = -93.998673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533376860, states[0] = -93.978782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541943188, states[0] = -93.965825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550158279, states[0] = -37.640808, states[40]= 0.001171
Saving checkpoint... 
Iteration: 558578194, states[0] = -93.984284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566625603, states[0] = -93.991757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575281064, states[0] = -93.981791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583946269, states[0] = -93.965674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591641807, states[0] = -93.971569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599989666, states[0] = -93.964941, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608304229, states[0] = -93.702403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616814151, states[0] = -93.998065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625071281, states[0] = -93.989462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633885949, states[0] = -93.966575, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642074750, states[0] = 15.681663, states[40]= 0.001334
Saving checkpoint... 
Iteration: 650291430, states[0] = -93.661687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658580280, states[0] = -93.984464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 666771776, states[0] = -93.998334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675238300, states[0] = -93.983040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 683681280, states[0] = -93.970465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692463506, states[0] = -93.940425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700630046, states[0] = -93.991952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709002115, states[0] = -93.991974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717652061, states[0] = -93.971034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725571191, states[0] = -93.972932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734290251, states[0] = -93.657478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742784802, states[0] = -93.998101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750999388, states[0] = -93.991980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 759199616, states[0] = -93.984236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767918700, states[0] = -93.965692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776785074, states[0] = -93.998018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785280655, states[0] = -93.981304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793958815, states[0] = -93.964967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802166574, states[0] = -44.044429, states[40]= 0.000536
Saving checkpoint... 
Iteration: 810775770, states[0] = -93.997982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818832689, states[0] = -93.997243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827868471, states[0] = -93.966419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836907201, states[0] = -93.995139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845736144, states[0] = -93.968912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854316354, states[0] = -93.735783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862743995, states[0] = -93.997733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870542751, states[0] = -93.974860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878970373, states[0] = -93.992784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887319638, states[0] = -93.979756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895373903, states[0] = -93.978008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903339705, states[0] = -93.979067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 912078813, states[0] = 14.054910, states[40]= 0.001608
Saving checkpoint... 
Iteration: 920701893, states[0] = -93.996581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 929333454, states[0] = -93.979206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 938024902, states[0] = 31.220694, states[40]= 0.000418
Saving checkpoint... 
Iteration: 946455860, states[0] = -93.934836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954786386, states[0] = -93.997584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962777635, states[0] = -93.997613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 971251686, states[0] = -93.981861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980322770, states[0] = -93.751849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 988494702, states[0] = -93.956667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997253877, states[0] = -93.981722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006023168, states[0] = 31.444104, states[40]= 0.000684
Saving checkpoint... 
Iteration: 1014243613, states[0] = -93.460171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022472908, states[0] = -93.945285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1030334453, states[0] = -93.778954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1039174112, states[0] = -93.984512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047786954, states[0] = -93.967411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056084183, states[0] = 11.826971, states[40]= 0.002018
Saving checkpoint... 
Iteration: 1063578317, states[0] = -93.971948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072194174, states[0] = -66.746464, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1079983082, states[0] = -93.963896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089207493, states[0] = -93.983160, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097813530, states[0] = -93.966782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106302859, states[0] = -93.697088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114551179, states[0] = -93.976635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123740307, states[0] = -93.968162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132356237, states[0] = -93.821698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141396877, states[0] = -93.976718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1149615113, states[0] = -93.970856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158056455, states[0] = 22.493020, states[40]= 0.000512
Saving checkpoint... 
Iteration: 1166523217, states[0] = -93.967867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174629348, states[0] = -93.990743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183619136, states[0] = -93.970680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192099958, states[0] = 4.541985, states[40]= 0.003326
Saving checkpoint... 
Iteration: 1201220550, states[0] = -93.982419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1209508771, states[0] = -93.973380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217891615, states[0] = -93.965079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225895469, states[0] = -93.964993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234710362, states[0] = -93.996130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1242710745, states[0] = -93.996123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250783456, states[0] = -93.996898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1258990210, states[0] = -93.991122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267709746, states[0] = -93.968455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276294667, states[0] = -93.670925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285106316, states[0] = -93.986516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294493482, states[0] = -93.955364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302573529, states[0] = -93.981540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310685471, states[0] = -93.994917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318436044, states[0] = -93.919214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327186538, states[0] = -93.983362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335930772, states[0] = -93.964131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344883758, states[0] = -93.994669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1353301530, states[0] = -93.979243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362292355, states[0] = -93.663064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371202940, states[0] = -93.982653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379436443, states[0] = -93.974981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388107010, states[0] = 0.709602, states[40]= 0.003683
Saving checkpoint... 
Iteration: 1396044080, states[0] = 26.594260, states[40]= 0.000253
Saving checkpoint... 
Iteration: 1403727753, states[0] = -93.967751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412244156, states[0] = -93.461986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421311136, states[0] = -93.978761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429262699, states[0] = -93.980383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437583758, states[0] = -93.970921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446280194, states[0] = -93.619676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454831323, states[0] = -93.995754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463315360, states[0] = -93.978521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471852892, states[0] = -93.965159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480617876, states[0] = -93.988614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488642337, states[0] = -93.991358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497502199, states[0] = -93.972868, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -93.838596
 - CaMKt in component CaMK (millimolar): 0.002074
 - cass in component intracellular_ions (millimolar): 0.000101
 - nai in component intracellular_ions (millimolar): 6.726782
 - nass in component intracellular_ions (millimolar): 6.726905
 - ki in component intracellular_ions (millimolar): 145.132464
 - kss in component intracellular_ions (millimolar): 145.132453
 - cansr in component intracellular_ions (millimolar): 1.829492
 - cajsr in component intracellular_ions (millimolar): 1.829339
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.004028
 - hf in component INa (dimensionless): 0.860292
 - hs in component INa (dimensionless): 0.860293
 - j in component INa (dimensionless): 0.860297
 - hsp in component INa (dimensionless): 0.689761
 - jp in component INa (dimensionless): 0.860299
 - mL in component INaL (dimensionless): 0.000061
 - hL in component INaL (dimensionless): 0.700275
 - hLp in component INaL (dimensionless): 0.504626
 - a in component Ito (dimensionless): 0.000670
 - iF in component Ito (dimensionless): 0.999843
 - iS in component Ito (dimensionless): 0.991408
 - ap in component Ito (dimensionless): 0.000341
 - iFp in component Ito (dimensionless): 0.999843
 - iSp in component Ito (dimensionless): 0.996555
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.996433
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005231
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.008101
 - xs1 in component IKs (dimensionless): 0.041580
 - xs2 in component IKs (dimensionless): 0.000099
 - xk1 in component IK1 (dimensionless): 0.997603
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
01:04:19 (10988): called boinc_finish(0)

</stderr_txt>
]]>


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