𝕏

Task 56073636

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_K1_75-conf_287_1
Workunit 26629062
Created 4 Jul 2024, 18:53:22 UTC
Sent 4 Jul 2024, 20:13:15 UTC
Report deadline 7 Jul 2024, 20:13:15 UTC
Received 5 Jul 2024, 8:19:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239650
Run time 1 hours 39 min 34 sec
CPU time 1 hours 38 min 9 sec
Validate state Valid
Credit 44.89
Device peak FLOPS 4.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.68 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_K1_75-conf_287.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_K1_75-conf_287_1_r1061645559_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_K1_75-conf_287_1_r1061645559_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.137293
     * GNaL_b in INaL: 0.005868
     * Gto_b in Ito: 0.084105
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031858
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.040847
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.549336
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032136
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 5545719, states[0] = 18.117587, states[40]= 0.003909
Saving checkpoint... 
Iteration: 11603162, states[0] = -18.075600, states[40]= 0.001256
Saving checkpoint... 
Iteration: 14452673, states[0] = -91.719979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23645163, states[0] = -55.977231, states[40]= 0.000027
Saving checkpoint... 
Iteration: 29863203, states[0] = -91.236784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36014659, states[0] = 27.849098, states[40]= 0.010336
Saving checkpoint... 
Iteration: 41890648, states[0] = -91.232131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51279750, states[0] = -90.326131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60650567, states[0] = -58.368475, states[40]= 0.000019
Saving checkpoint... 
Iteration: 69891566, states[0] = -91.128189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79308986, states[0] = -90.659605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88616099, states[0] = -27.617498, states[40]= 0.001014
Saving checkpoint... 
Iteration: 98106730, states[0] = -18.416410, states[40]= 0.001305
Saving checkpoint... 
Iteration: 107379562, states[0] = -91.036343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116742061, states[0] = -88.309890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125985808, states[0] = -91.216216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135322668, states[0] = -90.726208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144689345, states[0] = -77.084015, states[40]= 0.000001
Saving checkpoint... 
Iteration: 151042426, states[0] = 20.715663, states[40]= 0.001983
Saving checkpoint... 
Iteration: 160288881, states[0] = -90.327423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169709618, states[0] = -82.983651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179021432, states[0] = 27.244433, states[40]= 0.002031
Saving checkpoint... 
Iteration: 188355359, states[0] = -90.912837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197601090, states[0] = -12.573015, states[40]= 0.002047
Saving checkpoint... 
Iteration: 206931647, states[0] = -91.136325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216211279, states[0] = -83.363040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225426940, states[0] = -91.127194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234839967, states[0] = -90.829517, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244013454, states[0] = 28.054851, states[40]= 0.015054
Saving checkpoint... 
Iteration: 253443655, states[0] = -91.153615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262823402, states[0] = -90.717312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271931664, states[0] = -91.134480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281308153, states[0] = -90.579491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290055531, states[0] = 15.627033, states[40]= 0.002921
Saving checkpoint... 
Iteration: 299446729, states[0] = -91.157358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308783716, states[0] = -90.220934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317803079, states[0] = -90.522371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327118964, states[0] = -30.060644, states[40]= 0.000898
Saving checkpoint... 
Iteration: 336127005, states[0] = -37.602315, states[40]= 0.000440
Saving checkpoint... 
Iteration: 344956950, states[0] = -91.170140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354266375, states[0] = -89.738822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363533399, states[0] = 23.943901, states[40]= 0.001528
Saving checkpoint... 
Iteration: 372598532, states[0] = -10.058924, states[40]= 0.002542
Saving checkpoint... 
Iteration: 381902926, states[0] = -91.073820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391345674, states[0] = -90.859956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400636765, states[0] = -46.533977, states[40]= 0.000132
Saving checkpoint... 
Iteration: 409817267, states[0] = -90.665813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419023537, states[0] = 26.802052, states[40]= 0.001613
Saving checkpoint... 
Iteration: 428402134, states[0] = -91.071591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437850270, states[0] = -90.883672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447082329, states[0] = 2.569329, states[40]= 0.004398
Saving checkpoint... 
Iteration: 456345635, states[0] = -90.859414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465664685, states[0] = -66.525011, states[40]= 0.000004
Saving checkpoint... 
Iteration: 475110608, states[0] = -22.038170, states[40]= 0.001151
Saving checkpoint... 
Iteration: 484292654, states[0] = -90.379494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493686027, states[0] = -75.867346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 502891866, states[0] = -91.043447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512026722, states[0] = 25.996056, states[40]= 0.001411
Saving checkpoint... 
Iteration: 521218253, states[0] = -84.860504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530471915, states[0] = -91.185079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539636079, states[0] = -45.919198, states[40]= 0.000145
Saving checkpoint... 
Iteration: 548973445, states[0] = -91.186411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558209296, states[0] = -82.882016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567256344, states[0] = -89.283563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576304582, states[0] = -90.538453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585655853, states[0] = -61.361439, states[40]= 0.000011
Saving checkpoint... 
Iteration: 595046464, states[0] = 19.203292, states[40]= 0.002248
Saving checkpoint... 
Iteration: 604417597, states[0] = -91.106118, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613499024, states[0] = -91.205052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622715931, states[0] = -84.385849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631940003, states[0] = -91.145859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641306081, states[0] = -90.554987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 650739153, states[0] = -87.964301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659688778, states[0] = -76.840900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669146074, states[0] = -54.394251, states[40]= 0.000038
Saving checkpoint... 
Iteration: 678319912, states[0] = -90.686867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 687829431, states[0] = -90.759002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 697141709, states[0] = -50.835861, states[40]= 0.000068
Saving checkpoint... 
Iteration: 706190304, states[0] = -77.363241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715473056, states[0] = -91.185248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724772060, states[0] = -89.927766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734217948, states[0] = -84.798205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743466794, states[0] = -91.179029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752741410, states[0] = -88.188343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761789282, states[0] = -90.322707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770834399, states[0] = -90.791780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780282414, states[0] = -90.191032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789607038, states[0] = -18.510591, states[40]= 0.001300
Saving checkpoint... 
Iteration: 798848411, states[0] = -90.872381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807759176, states[0] = -89.428147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817161131, states[0] = -64.561301, states[40]= 0.000006
Saving checkpoint... 
Iteration: 826314018, states[0] = -90.634467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835254966, states[0] = -89.204830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844219783, states[0] = -85.155457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853516918, states[0] = 27.903506, states[40]= 0.005329
Saving checkpoint... 
Iteration: 863029896, states[0] = 25.071094, states[40]= 0.001422
Saving checkpoint... 
Iteration: 872350348, states[0] = -90.881909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881612894, states[0] = -24.257616, states[40]= 0.001110
Saving checkpoint... 
Iteration: 890836586, states[0] = -90.804961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900286497, states[0] = -90.271935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909228070, states[0] = -86.564939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917945072, states[0] = -91.151905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927314158, states[0] = -90.635249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936627116, states[0] = -37.702683, states[40]= 0.000434
Saving checkpoint... 
Iteration: 946046453, states[0] = 19.207957, states[40]= 0.002247
Saving checkpoint... 
Iteration: 955302115, states[0] = -90.507357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 964526239, states[0] = 26.127647, states[40]= 0.001423
Saving checkpoint... 
Iteration: 973539035, states[0] = 21.975345, states[40]= 0.001791
Saving checkpoint... 
Iteration: 982496395, states[0] = -91.201708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991585573, states[0] = 0.497548, states[40]= 0.004326
Saving checkpoint... 
Iteration: 1000934781, states[0] = -91.135841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010011532, states[0] = 28.017195, states[40]= 0.028100
Saving checkpoint... 
Iteration: 1019116852, states[0] = -28.051415, states[40]= 0.001000
Saving checkpoint... 
Iteration: 1028140187, states[0] = -49.536305, states[40]= 0.000084
Saving checkpoint... 
Iteration: 1037523348, states[0] = 26.846052, states[40]= 0.001638
Saving checkpoint... 
Iteration: 1046761532, states[0] = -89.536780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056114378, states[0] = -25.685895, states[40]= 0.001080
Saving checkpoint... 
Iteration: 1065351953, states[0] = -90.888945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1074417062, states[0] = -91.102727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1083558359, states[0] = 14.459926, states[40]= 0.003142
Saving checkpoint... 
Iteration: 1092706593, states[0] = -82.201967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102140674, states[0] = -49.954229, states[40]= 0.000079
Saving checkpoint... 
Iteration: 1111333487, states[0] = -90.784182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1120792796, states[0] = -90.378301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1129909253, states[0] = -91.085362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139101070, states[0] = -12.536652, states[40]= 0.002053
Saving checkpoint... 
Iteration: 1148551494, states[0] = 17.248564, states[40]= 0.002610
Saving checkpoint... 
Iteration: 1157676601, states[0] = -72.173742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166994715, states[0] = -91.199775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1176357696, states[0] = -90.915559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185608832, states[0] = -20.289911, states[40]= 0.001204
Saving checkpoint... 
Iteration: 1194705125, states[0] = -81.818808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1203674798, states[0] = -71.397406, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1213130450, states[0] = -40.786081, states[40]= 0.000295
Saving checkpoint... 
Iteration: 1222471877, states[0] = -91.181699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231745513, states[0] = -88.549104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240637585, states[0] = -47.259818, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1246692820, states[0] = -78.194642, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256216651, states[0] = -84.530946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259382469, states[0] = -91.010863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268598261, states[0] = -9.795709, states[40]= 0.002597
Saving checkpoint... 
Iteration: 1274689166, states[0] = -76.971310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1280780745, states[0] = -90.151715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286969194, states[0] = -91.178806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1290124328, states[0] = -35.103684, states[40]= 0.000582
Saving checkpoint... 
Iteration: 1294418636, states[0] = -91.104896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302108573, states[0] = -20.033387, states[40]= 0.001215
Saving checkpoint... 
Iteration: 1306392309, states[0] = -91.040802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1310773616, states[0] = -89.970251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1316704151, states[0] = -81.558335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1322563141, states[0] = 12.407392, states[40]= 0.003509
Saving checkpoint... 
Iteration: 1328879418, states[0] = -91.000357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1331763894, states[0] = -89.636031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336182085, states[0] = -74.389396, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339060524, states[0] = 13.543709, states[40]= 0.003310
Saving checkpoint... 
Iteration: 1343769912, states[0] = -89.856490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346547317, states[0] = 18.877018, states[40]= 0.002307
Saving checkpoint... 
Iteration: 1349295897, states[0] = -90.423322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1354916778, states[0] = -91.100774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357573929, states[0] = 7.280547, states[40]= 0.004191
Saving checkpoint... 
Iteration: 1362262456, states[0] = -89.575425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366595953, states[0] = -7.639455, states[40]= 0.003063
Saving checkpoint... 
Iteration: 1372539979, states[0] = 21.632610, states[40]= 0.001843
Saving checkpoint... 
Iteration: 1381686316, states[0] = -75.966620, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387494051, states[0] = -91.198289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395128521, states[0] = -39.003643, states[40]= 0.000370
Saving checkpoint... 
Iteration: 1401236511, states[0] = -87.671744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410642512, states[0] = -51.506373, states[40]= 0.000061
Saving checkpoint... 
Iteration: 1419749890, states[0] = -88.879492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425812914, states[0] = -90.621014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435098995, states[0] = -10.501003, states[40]= 0.002450
Saving checkpoint... 
Iteration: 1441362384, states[0] = -90.934881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447357400, states[0] = -90.912874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453416690, states[0] = -91.100111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459513040, states[0] = 28.054091, states[40]= 0.017187
Saving checkpoint... 
Iteration: 1465091640, states[0] = -3.939744, states[40]= 0.003799
Saving checkpoint... 
Iteration: 1471350140, states[0] = -90.877892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475223545, states[0] = -85.832235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1484441148, states[0] = -91.143456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490025531, states[0] = 26.315031, states[40]= 0.001449
Saving checkpoint... 
Iteration: 1497388378, states[0] = -91.028278, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.077208
 - CaMKt in component CaMK (millimolar): 0.012371
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.599138
 - nass in component intracellular_ions (millimolar): 6.599231
 - ki in component intracellular_ions (millimolar): 145.287703
 - kss in component intracellular_ions (millimolar): 145.287683
 - cansr in component intracellular_ions (millimolar): 1.638600
 - cajsr in component intracellular_ions (millimolar): 1.596132
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005322
 - hf in component INa (dimensionless): 0.796409
 - hs in component INa (dimensionless): 0.796371
 - j in component INa (dimensionless): 0.796104
 - hsp in component INa (dimensionless): 0.585281
 - jp in component INa (dimensionless): 0.795891
 - mL in component INaL (dimensionless): 0.000103
 - hL in component INaL (dimensionless): 0.582598
 - hLp in component INaL (dimensionless): 0.306624
 - a in component Ito (dimensionless): 0.000807
 - iF in component Ito (dimensionless): 0.999745
 - iS in component Ito (dimensionless): 0.573499
 - ap in component Ito (dimensionless): 0.000411
 - iFp in component Ito (dimensionless): 0.999745
 - iSp in component Ito (dimensionless): 0.628100
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914916
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999831
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002923
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.443878
 - xs1 in component IKs (dimensionless): 0.271198
 - xs2 in component IKs (dimensionless): 0.000135
 - xk1 in component IK1 (dimensionless): 0.998177
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:43:01 (197941): called boinc_finish(0)

</stderr_txt>
]]>


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