𝕏

Task 56073582

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_587_1
Workunit 26629035
Created 4 Jul 2024, 18:53:22 UTC
Sent 4 Jul 2024, 20:16:10 UTC
Report deadline 7 Jul 2024, 20:16:10 UTC
Received 7 Jul 2024, 11:06:27 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 40 min 46 sec
CPU time 37 min 44 sec
Validate state Valid
Credit 45.06
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.69 MB
Peak swap size 391.75 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_587.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_587_1_r1567558854_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_750-conf_587_1_r1567558854_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.753369
     * GNaL_b in INaL: 0.005763
     * Gto_b in Ito: 0.084266
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031954
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.163715
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.325533
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033221
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4000.000000
     * CL_0 in membrane: 750.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499625000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10528994, states[0] = 27.850497, states[40]= 0.000099
Saving checkpoint... 
Iteration: 21226603, states[0] = -84.290449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29709005, states[0] = -0.519261, states[40]= 0.000328
Saving checkpoint... 
Iteration: 40709675, states[0] = -84.169394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49658054, states[0] = -80.362888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59841125, states[0] = -84.208746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70289970, states[0] = -83.112427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80070688, states[0] = -84.063211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87433845, states[0] = 14.616018, states[40]= 0.000056
Saving checkpoint... 
Iteration: 97401793, states[0] = -84.479335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106174707, states[0] = 19.236325, states[40]= 0.000025
Saving checkpoint... 
Iteration: 117706523, states[0] = -84.600604, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128787917, states[0] = -82.621684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136501528, states[0] = 36.701384, states[40]= 0.960696
Saving checkpoint... 
Iteration: 146255294, states[0] = 30.112034, states[40]= 0.318893
Saving checkpoint... 
Iteration: 155862961, states[0] = -84.326633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165977017, states[0] = -84.269294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176553694, states[0] = -84.547107, states[40]= 0.000001
Saving checkpoint... 
Iteration: 187756925, states[0] = -84.408682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 198467858, states[0] = -8.112694, states[40]= 0.000355
Saving checkpoint... 
Iteration: 209156788, states[0] = -84.491369, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219217442, states[0] = -84.211830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229424817, states[0] = -84.537347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 238856807, states[0] = -84.632712, states[40]= 0.000001
Saving checkpoint... 
Iteration: 249016359, states[0] = 31.629550, states[40]= 0.006347
Saving checkpoint... 
Iteration: 259549859, states[0] = 19.167266, states[40]= 0.000026
Saving checkpoint... 
Iteration: 269302422, states[0] = 17.901943, states[40]= 0.000032
Saving checkpoint... 
Iteration: 281208179, states[0] = -84.599824, states[40]= 0.000001
Saving checkpoint... 
Iteration: 292115041, states[0] = -84.640985, states[40]= 0.000001
Saving checkpoint... 
Iteration: 302867251, states[0] = -84.344152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312448709, states[0] = 6.367176, states[40]= 0.000173
Saving checkpoint... 
Iteration: 322704046, states[0] = -84.120092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331813930, states[0] = -84.565332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 339605557, states[0] = -84.285198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349401740, states[0] = -84.473799, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360880801, states[0] = -49.004446, states[40]= 0.000033
Saving checkpoint... 
Iteration: 372058376, states[0] = 14.871629, states[40]= 0.000054
Saving checkpoint... 
Iteration: 381379759, states[0] = 30.442987, states[40]= 0.384115
Saving checkpoint... 
Iteration: 391751672, states[0] = -84.383735, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401719456, states[0] = -9.759839, states[40]= 0.000337
Saving checkpoint... 
Iteration: 410433473, states[0] = -83.950753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420852220, states[0] = -18.373456, states[40]= 0.000223
Saving checkpoint... 
Iteration: 429499142, states[0] = -41.919503, states[40]= 0.000076
Saving checkpoint... 
Iteration: 438545765, states[0] = -83.684076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449201282, states[0] = -84.585512, states[40]= 0.000001
Saving checkpoint... 
Iteration: 460358101, states[0] = -84.296264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470739351, states[0] = -31.574021, states[40]= 0.000179
Saving checkpoint... 
Iteration: 479528895, states[0] = -84.477811, states[40]= 0.000001
Saving checkpoint... 
Iteration: 490098874, states[0] = -84.618188, states[40]= 0.000001
Saving checkpoint... 
Iteration: 496901212, states[0] = 29.396488, states[40]= 0.000198
Saving checkpoint... 
Iteration: 505460288, states[0] = -84.598850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 515387206, states[0] = -55.987031, states[40]= 0.000013
Saving checkpoint... 
Iteration: 524420813, states[0] = -83.684580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535424154, states[0] = -84.530038, states[40]= 0.000001
Saving checkpoint... 
Iteration: 546779661, states[0] = 28.156325, states[40]= 0.000062
Saving checkpoint... 
Iteration: 557440470, states[0] = -84.010797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 566259536, states[0] = 30.788950, states[40]= 0.071518
Saving checkpoint... 
Iteration: 576107095, states[0] = -23.768764, states[40]= 0.000207
Saving checkpoint... 
Iteration: 585561276, states[0] = -83.973922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594950690, states[0] = -84.090286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605467757, states[0] = -84.206336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 617223852, states[0] = -84.615777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 626841610, states[0] = -84.198767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637577893, states[0] = 3.784865, states[40]= 0.000228
Saving checkpoint... 
Iteration: 646787572, states[0] = -84.499074, states[40]= 0.000001
Saving checkpoint... 
Iteration: 654350889, states[0] = -84.617689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 664380625, states[0] = -84.394504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 674485649, states[0] = -84.305166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685021600, states[0] = -84.451296, states[40]= 0.000001
Saving checkpoint... 
Iteration: 695180270, states[0] = -84.540727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704798620, states[0] = -83.788156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714892328, states[0] = -61.867027, states[40]= 0.000006
Saving checkpoint... 
Iteration: 722289429, states[0] = 24.070005, states[40]= 0.000012
Saving checkpoint... 
Iteration: 731637622, states[0] = 31.510905, states[40]= 0.023905
Saving checkpoint... 
Iteration: 740372822, states[0] = -40.516920, states[40]= 0.000088
Saving checkpoint... 
Iteration: 749524994, states[0] = -84.460852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760944413, states[0] = 8.879790, states[40]= 0.000127
Saving checkpoint... 
Iteration: 772345257, states[0] = -84.218404, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782902287, states[0] = -84.467254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 792765229, states[0] = 31.676386, states[40]= 0.009474
Saving checkpoint... 
Iteration: 801073869, states[0] = 6.276646, states[40]= 0.000175
Saving checkpoint... 
Iteration: 811240182, states[0] = -32.447094, states[40]= 0.000171
Saving checkpoint... 
Iteration: 821583967, states[0] = -84.590899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 831773812, states[0] = 30.161020, states[40]= 0.000457
Saving checkpoint... 
Iteration: 843010162, states[0] = 30.978348, states[40]= 0.057267
Saving checkpoint... 
Iteration: 854069270, states[0] = -84.035923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 863682961, states[0] = 15.091246, states[40]= 0.000052
Saving checkpoint... 
Iteration: 872477734, states[0] = -84.259645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881387909, states[0] = -56.758879, states[40]= 0.000012
Saving checkpoint... 
Iteration: 891137530, states[0] = -56.333692, states[40]= 0.000013
Saving checkpoint... 
Iteration: 900219030, states[0] = -84.208496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909763740, states[0] = 31.631385, states[40]= 0.016070
Saving checkpoint... 
Iteration: 920703499, states[0] = 3.398613, states[40]= 0.000236
Saving checkpoint... 
Iteration: 931337947, states[0] = -84.169412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941670857, states[0] = 21.101586, states[40]= 0.000018
Saving checkpoint... 
Iteration: 950694269, states[0] = 8.963679, states[40]= 0.000126
Saving checkpoint... 
Iteration: 960891486, states[0] = -60.859268, states[40]= 0.000007
Saving checkpoint... 
Iteration: 970740568, states[0] = -84.323506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978824225, states[0] = 6.064414, states[40]= 0.000179
Saving checkpoint... 
Iteration: 987730927, states[0] = -84.617635, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997000817, states[0] = -84.368652, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005680046, states[0] = -84.534393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1016886535, states[0] = -84.410275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028554404, states[0] = -84.532566, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1038545024, states[0] = -83.629798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048268562, states[0] = -63.334364, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1058441070, states[0] = -84.006018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068517010, states[0] = -61.472398, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1078201975, states[0] = 4.372658, states[40]= 0.000215
Saving checkpoint... 
Iteration: 1089741400, states[0] = -84.627504, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1100355694, states[0] = -22.218271, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1109812999, states[0] = -83.978983, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117976761, states[0] = -17.837497, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1128132728, states[0] = -51.053334, states[40]= 0.000026
Saving checkpoint... 
Iteration: 1138908119, states[0] = 26.791438, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1148839768, states[0] = -84.177013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1159473826, states[0] = -84.605580, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1169970297, states[0] = -84.600713, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179097185, states[0] = -12.698774, states[40]= 0.000294
Saving checkpoint... 
Iteration: 1189370562, states[0] = -84.342288, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1199293095, states[0] = 22.400393, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1210720902, states[0] = -84.213843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1221326665, states[0] = -84.571651, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1231204516, states[0] = 2.737987, states[40]= 0.000251
Saving checkpoint... 
Iteration: 1241026637, states[0] = -73.569883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1251129628, states[0] = -47.717254, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1260950511, states[0] = -84.076036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271270692, states[0] = 30.981818, states[40]= 0.001370
Saving checkpoint... 
Iteration: 1280245120, states[0] = -84.627793, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1288720333, states[0] = -84.208925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299323648, states[0] = -84.565032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1310538512, states[0] = -84.489032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320458898, states[0] = -0.313657, states[40]= 0.000314
Saving checkpoint... 
Iteration: 1330126213, states[0] = 36.389412, states[40]= 0.763536
Saving checkpoint... 
Iteration: 1339741002, states[0] = -84.318505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350044389, states[0] = 21.797594, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1361066251, states[0] = -84.001617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371992614, states[0] = -84.325415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381872514, states[0] = -84.628286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1392165205, states[0] = -83.102386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1402097129, states[0] = -84.598809, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1410832979, states[0] = 0.357833, states[40]= 0.000301
Saving checkpoint... 
Iteration: 1419863237, states[0] = -30.359985, states[40]= 0.000189
Saving checkpoint... 
Iteration: 1425957993, states[0] = -84.126547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435687023, states[0] = -83.964016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447550818, states[0] = 18.705707, states[40]= 0.000028
Saving checkpoint... 
Iteration: 1456440244, states[0] = -84.546716, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1465852738, states[0] = -84.604796, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1476502760, states[0] = -45.718479, states[40]= 0.000049
Saving checkpoint... 
Iteration: 1484871755, states[0] = -84.341932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494364411, states[0] = -84.617799, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.504330
 - CaMKt in component CaMK (millimolar): 0.029710
 - cass in component intracellular_ions (millimolar): 0.000099
 - nai in component intracellular_ions (millimolar): 6.754555
 - nass in component intracellular_ions (millimolar): 6.754696
 - ki in component intracellular_ions (millimolar): 144.957412
 - kss in component intracellular_ions (millimolar): 144.957385
 - cansr in component intracellular_ions (millimolar): 1.946667
 - cajsr in component intracellular_ions (millimolar): 1.780551
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.010305
 - hf in component INa (dimensionless): 0.570527
 - hs in component INa (dimensionless): 0.570424
 - j in component INa (dimensionless): 0.569870
 - hsp in component INa (dimensionless): 0.323858
 - jp in component INa (dimensionless): 0.569457
 - mL in component INaL (dimensionless): 0.000357
 - hL in component INaL (dimensionless): 0.361571
 - hLp in component INaL (dimensionless): 0.161214
 - a in component Ito (dimensionless): 0.001257
 - iF in component Ito (dimensionless): 0.999195
 - iS in component Ito (dimensionless): 0.417147
 - ap in component Ito (dimensionless): 0.000640
 - iFp in component Ito (dimensionless): 0.999195
 - iSp in component Ito (dimensionless): 0.454002
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.864469
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.998004
 - jca in component ICaL (dimensionless): 0.999322
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004875
 - xrf in component IKr (dimensionless): 0.000101
 - xrs in component IKr (dimensionless): 0.628048
 - xs1 in component IKs (dimensionless): 0.354295
 - xs2 in component IKs (dimensionless): 0.000282
 - xk1 in component IK1 (dimensionless): 0.996799
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:06:12 (11393): called boinc_finish(0)

</stderr_txt>
]]>


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