𝕏

Task 56073569

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_887_0
Workunit 26629029
Created 4 Jul 2024, 18:53:17 UTC
Sent 4 Jul 2024, 20:18:23 UTC
Report deadline 7 Jul 2024, 20:18:27 UTC
Received 7 Jul 2024, 15:55:31 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 40 min 24 sec
CPU time 38 min 16 sec
Validate state Valid
Credit 44.72
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.20 MB
Peak swap size 391.75 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_887.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_887_0_r1532578866_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_887_0_r1532578866_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 104.304391
     * GNaL_b in INaL: 0.005836
     * Gto_b in Ito: 0.084087
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031993
     * GKs_b in IKs: 0.001936
     * GK1_b in IK1: 0.162769
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.443156
     * GKb_b in IKb: 0.003795
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032681
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 9569179, states[0] = -84.520092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 17424194, states[0] = -7.566886, states[40]= 0.000502
Saving checkpoint... 
Iteration: 27534426, states[0] = -84.230292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38191997, states[0] = -84.151610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47945333, states[0] = -84.599675, states[40]= 0.000001
Saving checkpoint... 
Iteration: 59693129, states[0] = 30.178865, states[40]= 0.000517
Saving checkpoint... 
Iteration: 69493284, states[0] = -81.923021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79950617, states[0] = -84.612361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89342637, states[0] = 30.447259, states[40]= 0.383940
Saving checkpoint... 
Iteration: 100096901, states[0] = -10.114657, states[40]= 0.000304
Saving checkpoint... 
Iteration: 111273562, states[0] = -84.577276, states[40]= 0.000001
Saving checkpoint... 
Iteration: 120953762, states[0] = -84.615559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 131048702, states[0] = 22.424969, states[40]= 0.000011
Saving checkpoint... 
Iteration: 141042158, states[0] = 25.671828, states[40]= 0.000013
Saving checkpoint... 
Iteration: 151079293, states[0] = 6.349198, states[40]= 0.000150
Saving checkpoint... 
Iteration: 161175810, states[0] = -83.843952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172665569, states[0] = -84.704432, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183421745, states[0] = 1.309593, states[40]= 0.000248
Saving checkpoint... 
Iteration: 193233744, states[0] = -84.387417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202609292, states[0] = -84.568711, states[40]= 0.000001
Saving checkpoint... 
Iteration: 212389614, states[0] = 20.718232, states[40]= 0.000015
Saving checkpoint... 
Iteration: 222045251, states[0] = 26.090707, states[40]= 0.000016
Saving checkpoint... 
Iteration: 231702955, states[0] = 29.772167, states[40]= 0.000336
Saving checkpoint... 
Iteration: 242301032, states[0] = -84.633673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 251081261, states[0] = 8.213463, states[40]= 0.000119
Saving checkpoint... 
Iteration: 259583200, states[0] = -84.452322, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269762826, states[0] = -1.316486, states[40]= 0.000295
Saving checkpoint... 
Iteration: 278402778, states[0] = 15.663506, states[40]= 0.000038
Saving checkpoint... 
Iteration: 288651052, states[0] = -84.664952, states[40]= 0.000001
Saving checkpoint... 
Iteration: 298563354, states[0] = -84.331927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309781117, states[0] = -18.251197, states[40]= 0.000209
Saving checkpoint... 
Iteration: 320548896, states[0] = -84.224979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 330049909, states[0] = 26.414140, states[40]= 0.000020
Saving checkpoint... 
Iteration: 339921218, states[0] = -84.453812, states[40]= 0.000001
Saving checkpoint... 
Iteration: 349862749, states[0] = -84.043827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358907943, states[0] = -84.379660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367269417, states[0] = -84.511541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 377924071, states[0] = -84.457241, states[40]= 0.000001
Saving checkpoint... 
Iteration: 388035828, states[0] = 31.615573, states[40]= 0.006282
Saving checkpoint... 
Iteration: 397693882, states[0] = 30.121595, states[40]= 0.160058
Saving checkpoint... 
Iteration: 407977352, states[0] = -84.633228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 417254280, states[0] = -84.431873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 426648099, states[0] = -84.640382, states[40]= 0.000001
Saving checkpoint... 
Iteration: 435836210, states[0] = -74.235306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444793571, states[0] = -24.747866, states[40]= 0.000193
Saving checkpoint... 
Iteration: 455732464, states[0] = 22.012080, states[40]= 0.000012
Saving checkpoint... 
Iteration: 467169113, states[0] = -71.660075, states[40]= 0.000001
Saving checkpoint... 
Iteration: 478007589, states[0] = -84.686659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489010488, states[0] = -84.690487, states[40]= 0.000001
Saving checkpoint... 
Iteration: 499631437, states[0] = -84.584896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 509995379, states[0] = -84.659912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 519006345, states[0] = -84.679968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 529494006, states[0] = -57.242488, states[40]= 0.000012
Saving checkpoint... 
Iteration: 540790653, states[0] = -15.901613, states[40]= 0.000229
Saving checkpoint... 
Iteration: 550731768, states[0] = 24.571465, states[40]= 0.000010
Saving checkpoint... 
Iteration: 561092947, states[0] = 10.467817, states[40]= 0.000087
Saving checkpoint... 
Iteration: 570290929, states[0] = -84.548965, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579387485, states[0] = 29.615731, states[40]= 0.000284
Saving checkpoint... 
Iteration: 588474521, states[0] = -32.584720, states[40]= 0.000161
Saving checkpoint... 
Iteration: 598348627, states[0] = -84.686994, states[40]= 0.000001
Saving checkpoint... 
Iteration: 608137478, states[0] = -27.425807, states[40]= 0.000191
Saving checkpoint... 
Iteration: 617896890, states[0] = -84.216510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 629336838, states[0] = -84.661698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 640075684, states[0] = 21.691780, states[40]= 0.000012
Saving checkpoint... 
Iteration: 650548548, states[0] = -84.077535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661104397, states[0] = 6.601101, states[40]= 0.000145
Saving checkpoint... 
Iteration: 670432306, states[0] = 10.146254, states[40]= 0.000091
Saving checkpoint... 
Iteration: 680052113, states[0] = 31.426510, states[40]= 0.003452
Saving checkpoint... 
Iteration: 689073880, states[0] = 23.712749, states[40]= 0.000010
Saving checkpoint... 
Iteration: 697792912, states[0] = -9.536266, states[40]= 0.000309
Saving checkpoint... 
Iteration: 708388301, states[0] = 31.172939, states[40]= 0.002072
Saving checkpoint... 
Iteration: 719231989, states[0] = -84.188782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728953997, states[0] = -84.502696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 738739890, states[0] = 25.150106, states[40]= 0.000011
Saving checkpoint... 
Iteration: 748148317, states[0] = -31.645114, states[40]= 0.000170
Saving checkpoint... 
Iteration: 756965483, states[0] = -84.539738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 766940531, states[0] = -84.434204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 777063241, states[0] = 29.881469, states[40]= 0.000375
Saving checkpoint... 
Iteration: 788493911, states[0] = -42.767628, states[40]= 0.000069
Saving checkpoint... 
Iteration: 799671228, states[0] = -84.642127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 809081273, states[0] = 23.060289, states[40]= 0.000010
Saving checkpoint... 
Iteration: 820002609, states[0] = -84.635035, states[40]= 0.000001
Saving checkpoint... 
Iteration: 830641408, states[0] = -84.556878, states[40]= 0.000001
Saving checkpoint... 
Iteration: 840131158, states[0] = -7.204684, states[40]= 0.000326
Saving checkpoint... 
Iteration: 850081716, states[0] = 23.813925, states[40]= 0.000009
Saving checkpoint... 
Iteration: 859262273, states[0] = -84.345092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869181969, states[0] = -62.337151, states[40]= 0.000006
Saving checkpoint... 
Iteration: 880355828, states[0] = -84.668404, states[40]= 0.000001
Saving checkpoint... 
Iteration: 890468767, states[0] = -9.047925, states[40]= 0.000311
Saving checkpoint... 
Iteration: 900725204, states[0] = 31.620348, states[40]= 0.017785
Saving checkpoint... 
Iteration: 911110696, states[0] = 10.328136, states[40]= 0.000089
Saving checkpoint... 
Iteration: 920751893, states[0] = 23.824726, states[40]= 0.000010
Saving checkpoint... 
Iteration: 930923640, states[0] = -84.287725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940360445, states[0] = -84.670032, states[40]= 0.000001
Saving checkpoint... 
Iteration: 951750205, states[0] = 25.301628, states[40]= 0.000012
Saving checkpoint... 
Iteration: 963141363, states[0] = -11.582334, states[40]= 0.000285
Saving checkpoint... 
Iteration: 975104626, states[0] = 15.482514, states[40]= 0.000039
Saving checkpoint... 
Iteration: 985859553, states[0] = -68.786036, states[40]= 0.000002
Saving checkpoint... 
Iteration: 996231797, states[0] = -84.063005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006393142, states[0] = 30.792926, states[40]= 0.074302
Saving checkpoint... 
Iteration: 1013092200, states[0] = 22.717938, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1022630614, states[0] = -84.476750, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1033277908, states[0] = -84.380547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043112767, states[0] = 12.899009, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1054328807, states[0] = -84.581238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1065110041, states[0] = 14.991754, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1074122736, states[0] = 8.028102, states[40]= 0.000121
Saving checkpoint... 
Iteration: 1083060908, states[0] = 30.006403, states[40]= 0.195947
Saving checkpoint... 
Iteration: 1092665193, states[0] = -84.583673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102752056, states[0] = 27.731995, states[40]= 0.000050
Saving checkpoint... 
Iteration: 1113599233, states[0] = -84.282065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124426703, states[0] = 24.762705, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1135327464, states[0] = -84.563332, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145768108, states[0] = 21.466102, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1154850674, states[0] = -48.333513, states[40]= 0.000037
Saving checkpoint... 
Iteration: 1164034786, states[0] = -84.658636, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1173753715, states[0] = 28.474696, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1182906110, states[0] = -84.042427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193416354, states[0] = 30.208108, states[40]= 0.000540
Saving checkpoint... 
Iteration: 1204512152, states[0] = -39.983827, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1214457985, states[0] = 11.028312, states[40]= 0.000080
Saving checkpoint... 
Iteration: 1224582197, states[0] = -84.108823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1234325547, states[0] = -84.538883, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1243923784, states[0] = -84.168300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253511602, states[0] = -36.728907, states[40]= 0.000122
Saving checkpoint... 
Iteration: 1264539858, states[0] = -68.384312, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1275895912, states[0] = -83.701650, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285085665, states[0] = 30.751169, states[40]= 0.001071
Saving checkpoint... 
Iteration: 1295096927, states[0] = 26.945984, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1303824415, states[0] = -10.845238, states[40]= 0.000294
Saving checkpoint... 
Iteration: 1311976581, states[0] = -84.462245, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1322026929, states[0] = -84.622034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332004298, states[0] = -84.559946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1342731312, states[0] = -84.689578, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1352915088, states[0] = -84.043238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362508051, states[0] = -26.868907, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1372465221, states[0] = 11.409809, states[40]= 0.000076
Saving checkpoint... 
Iteration: 1381122486, states[0] = 16.777690, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1391566890, states[0] = -83.590497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404076911, states[0] = 30.002464, states[40]= 0.199073
Saving checkpoint... 
Iteration: 1414198353, states[0] = -49.836120, states[40]= 0.000031
Saving checkpoint... 
Iteration: 1424722009, states[0] = -84.666302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433357505, states[0] = -84.599272, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1442748963, states[0] = 30.997289, states[40]= 0.058501
Saving checkpoint... 
Iteration: 1453567926, states[0] = -83.361034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463020351, states[0] = -84.584573, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472392738, states[0] = -84.668104, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481085890, states[0] = 31.399167, states[40]= 0.032179
Saving checkpoint... 
Iteration: 1489824959, states[0] = -2.223245, states[40]= 0.000306
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.565408
 - CaMKt in component CaMK (millimolar): 0.038828
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.817203
 - nass in component intracellular_ions (millimolar): 6.817358
 - ki in component intracellular_ions (millimolar): 144.847276
 - kss in component intracellular_ions (millimolar): 144.847248
 - cansr in component intracellular_ions (millimolar): 2.052051
 - cajsr in component intracellular_ions (millimolar): 1.807258
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010242
 - hf in component INa (dimensionless): 0.572984
 - hs in component INa (dimensionless): 0.572831
 - j in component INa (dimensionless): 0.571995
 - hsp in component INa (dimensionless): 0.325910
 - jp in component INa (dimensionless): 0.571306
 - mL in component INaL (dimensionless): 0.000353
 - hL in component INaL (dimensionless): 0.346499
 - hLp in component INaL (dimensionless): 0.151092
 - a in component Ito (dimensionless): 0.001252
 - iF in component Ito (dimensionless): 0.999203
 - iS in component Ito (dimensionless): 0.366016
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999203
 - iSp in component Ito (dimensionless): 0.400421
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.843105
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995756
 - jca in component ICaL (dimensionless): 0.998121
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005898
 - xrf in component IKr (dimensionless): 0.000403
 - xrs in component IKr (dimensionless): 0.673648
 - xs1 in component IKs (dimensionless): 0.385582
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996785
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
11:55:21 (15509): called boinc_finish(0)

</stderr_txt>
]]>


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