𝕏

Task 56073568

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_87_1
Workunit 26629028
Created 4 Jul 2024, 18:53:17 UTC
Sent 4 Jul 2024, 20:18:23 UTC
Report deadline 7 Jul 2024, 20:18:27 UTC
Received 7 Jul 2024, 13:06:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 8 sec
CPU time 38 min 4 sec
Validate state Valid
Credit 44.93
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.70 MB
Peak swap size 391.88 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_87.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_87_1_r1487039280_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_666-conf_87_1_r1487039280_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000150.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.767845
     * GNaL_b in INaL: 0.005918
     * Gto_b in Ito: 0.083651
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031838
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.164075
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.113922
     * GKb_b in IKb: 0.003806
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032321
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 4500.000000
     * CL_0 in membrane: 666.700000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499741650.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11325790, states[0] = -84.729660, states[40]= 0.000001
Saving checkpoint... 
Iteration: 19448176, states[0] = -34.149240, states[40]= 0.000179
Saving checkpoint... 
Iteration: 29099404, states[0] = -16.432579, states[40]= 0.000244
Saving checkpoint... 
Iteration: 37978998, states[0] = -84.675463, states[40]= 0.000001
Saving checkpoint... 
Iteration: 48800505, states[0] = -53.393993, states[40]= 0.000020
Saving checkpoint... 
Iteration: 60469804, states[0] = -55.783356, states[40]= 0.000014
Saving checkpoint... 
Iteration: 69651780, states[0] = -84.687379, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79698638, states[0] = 28.646493, states[40]= 0.000107
Saving checkpoint... 
Iteration: 89588795, states[0] = -84.514914, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98244231, states[0] = -84.465341, states[40]= 0.000001
Saving checkpoint... 
Iteration: 106773311, states[0] = -20.661221, states[40]= 0.000195
Saving checkpoint... 
Iteration: 116779415, states[0] = -26.941637, states[40]= 0.000192
Saving checkpoint... 
Iteration: 125877504, states[0] = -84.265229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136080592, states[0] = 5.115018, states[40]= 0.000166
Saving checkpoint... 
Iteration: 146425877, states[0] = -3.341977, states[40]= 0.000309
Saving checkpoint... 
Iteration: 154012588, states[0] = 30.420732, states[40]= 0.378298
Saving checkpoint... 
Iteration: 163896244, states[0] = -84.372555, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173598808, states[0] = -84.536525, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182299216, states[0] = -84.635973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192253978, states[0] = -84.486650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 203718273, states[0] = 22.799298, states[40]= 0.000010
Saving checkpoint... 
Iteration: 214695574, states[0] = 31.440149, states[40]= 0.003381
Saving checkpoint... 
Iteration: 225284339, states[0] = -84.589403, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235444621, states[0] = -18.639635, states[40]= 0.000203
Saving checkpoint... 
Iteration: 244372311, states[0] = 29.087857, states[40]= 0.000163
Saving checkpoint... 
Iteration: 253016944, states[0] = 31.015215, states[40]= 0.465275
Saving checkpoint... 
Iteration: 263695206, states[0] = 31.696695, states[40]= 0.009211
Saving checkpoint... 
Iteration: 273831068, states[0] = -77.356830, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284930520, states[0] = -84.506544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 295021755, states[0] = 30.072832, states[40]= 0.180114
Saving checkpoint... 
Iteration: 303461606, states[0] = -33.718369, states[40]= 0.000151
Saving checkpoint... 
Iteration: 312922228, states[0] = -84.464210, states[40]= 0.000001
Saving checkpoint... 
Iteration: 321572158, states[0] = -84.376859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331745601, states[0] = 11.967979, states[40]= 0.000067
Saving checkpoint... 
Iteration: 342468725, states[0] = -39.298417, states[40]= 0.000098
Saving checkpoint... 
Iteration: 351877256, states[0] = -84.173857, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362457285, states[0] = -25.762204, states[40]= 0.000192
Saving checkpoint... 
Iteration: 373842741, states[0] = -82.228333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382778572, states[0] = -10.900814, states[40]= 0.000287
Saving checkpoint... 
Iteration: 392937148, states[0] = -84.508741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 401661830, states[0] = -84.670564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411425843, states[0] = 6.288967, states[40]= 0.000146
Saving checkpoint... 
Iteration: 419512402, states[0] = -82.484904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 427862393, states[0] = -83.990247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435883579, states[0] = -84.188721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447015856, states[0] = -84.701166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 458245896, states[0] = -84.375005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469146384, states[0] = -44.321580, states[40]= 0.000058
Saving checkpoint... 
Iteration: 478591368, states[0] = -84.433039, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487835436, states[0] = -69.379787, states[40]= 0.000002
Saving checkpoint... 
Iteration: 497342832, states[0] = -84.685692, states[40]= 0.000001
Saving checkpoint... 
Iteration: 506403928, states[0] = 20.940089, states[40]= 0.000014
Saving checkpoint... 
Iteration: 515667242, states[0] = -84.667436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 525939769, states[0] = -84.489412, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536626998, states[0] = -84.563003, states[40]= 0.000001
Saving checkpoint... 
Iteration: 545950000, states[0] = -84.525340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 556709803, states[0] = 31.699896, states[40]= 0.009385
Saving checkpoint... 
Iteration: 567211261, states[0] = -84.082474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577684696, states[0] = -84.691471, states[40]= 0.000001
Saving checkpoint... 
Iteration: 586054113, states[0] = 29.764405, states[40]= 0.000323
Saving checkpoint... 
Iteration: 595179376, states[0] = -76.099484, states[40]= 0.000001
Saving checkpoint... 
Iteration: 604004645, states[0] = -84.664816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 614835360, states[0] = -61.221708, states[40]= 0.000007
Saving checkpoint... 
Iteration: 625447191, states[0] = -1.132891, states[40]= 0.000282
Saving checkpoint... 
Iteration: 634746402, states[0] = 19.589715, states[40]= 0.000018
Saving checkpoint... 
Iteration: 645413680, states[0] = 19.552616, states[40]= 0.000018
Saving checkpoint... 
Iteration: 654671536, states[0] = -84.659180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 663656285, states[0] = -84.624402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673095786, states[0] = 12.090520, states[40]= 0.000066
Saving checkpoint... 
Iteration: 682669541, states[0] = -84.651682, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693578116, states[0] = -84.290759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703575452, states[0] = -84.269215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713001449, states[0] = -84.644650, states[40]= 0.000001
Saving checkpoint... 
Iteration: 723241472, states[0] = -84.257459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732772975, states[0] = 7.693631, states[40]= 0.000123
Saving checkpoint... 
Iteration: 742432039, states[0] = 12.398995, states[40]= 0.000063
Saving checkpoint... 
Iteration: 751363264, states[0] = -84.692533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 760900248, states[0] = -84.184398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770354251, states[0] = -84.675647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 781754709, states[0] = 19.110149, states[40]= 0.000019
Saving checkpoint... 
Iteration: 792559242, states[0] = -84.107770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 803075634, states[0] = 25.535668, states[40]= 0.000012
Saving checkpoint... 
Iteration: 813102529, states[0] = 12.236966, states[40]= 0.000064
Saving checkpoint... 
Iteration: 823204592, states[0] = -83.539388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831833128, states[0] = -46.419038, states[40]= 0.000046
Saving checkpoint... 
Iteration: 841462609, states[0] = -5.134272, states[40]= 0.000321
Saving checkpoint... 
Iteration: 851625864, states[0] = -84.494955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 861846897, states[0] = -60.229552, states[40]= 0.000008
Saving checkpoint... 
Iteration: 872285965, states[0] = -84.462344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 882805625, states[0] = -13.204061, states[40]= 0.000258
Saving checkpoint... 
Iteration: 892867413, states[0] = -81.626927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 901077789, states[0] = 26.728476, states[40]= 0.000023
Saving checkpoint... 
Iteration: 909953302, states[0] = -84.456233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918799963, states[0] = -5.277612, states[40]= 0.000319
Saving checkpoint... 
Iteration: 928498566, states[0] = -39.858481, states[40]= 0.000093
Saving checkpoint... 
Iteration: 938710938, states[0] = -84.695884, states[40]= 0.000001
Saving checkpoint... 
Iteration: 949215905, states[0] = -83.846628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958547779, states[0] = -83.763881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968700682, states[0] = -84.676727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 978866595, states[0] = -77.599479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 988489088, states[0] = -26.298182, states[40]= 0.000192
Saving checkpoint... 
Iteration: 997326469, states[0] = -84.582162, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1007506550, states[0] = -44.211548, states[40]= 0.000059
Saving checkpoint... 
Iteration: 1016872034, states[0] = -80.686978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027730167, states[0] = 31.473746, states[40]= 0.029206
Saving checkpoint... 
Iteration: 1038032460, states[0] = -84.666433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1047918051, states[0] = -84.204232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057482504, states[0] = -14.897535, states[40]= 0.000236
Saving checkpoint... 
Iteration: 1067148895, states[0] = -14.024407, states[40]= 0.000248
Saving checkpoint... 
Iteration: 1076668137, states[0] = -84.592564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1085104807, states[0] = 18.299344, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1095613422, states[0] = -84.373346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106558932, states[0] = -83.896579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1117209723, states[0] = -80.214313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128189348, states[0] = -55.344195, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1138169738, states[0] = -33.403274, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1148416144, states[0] = 29.576685, states[40]= 0.000263
Saving checkpoint... 
Iteration: 1159745681, states[0] = 30.870235, states[40]= 0.001227
Saving checkpoint... 
Iteration: 1169070003, states[0] = 31.368070, states[40]= 0.035727
Saving checkpoint... 
Iteration: 1179259382, states[0] = -84.211684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188491408, states[0] = -17.614158, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1198395827, states[0] = 34.586783, states[40]= 0.836036
Saving checkpoint... 
Iteration: 1206616655, states[0] = -84.357916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216739904, states[0] = 31.521294, states[40]= 0.026371
Saving checkpoint... 
Iteration: 1226792101, states[0] = 10.984188, states[40]= 0.000077
Saving checkpoint... 
Iteration: 1238221160, states[0] = -82.804757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247506978, states[0] = -31.702721, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1256874504, states[0] = -70.144859, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1266901321, states[0] = -83.916947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276605178, states[0] = -84.263453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285434528, states[0] = 24.892273, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1294908190, states[0] = -84.002395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304826494, states[0] = -12.928223, states[40]= 0.000262
Saving checkpoint... 
Iteration: 1315735523, states[0] = 33.313794, states[40]= 0.707857
Saving checkpoint... 
Iteration: 1325809559, states[0] = 3.262715, states[40]= 0.000201
Saving checkpoint... 
Iteration: 1335330194, states[0] = -84.533615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1345013579, states[0] = -84.583044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1355224233, states[0] = -81.783773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366172579, states[0] = -23.999247, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1376020067, states[0] = -84.595442, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1386338518, states[0] = -84.551275, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1394517970, states[0] = -35.643275, states[40]= 0.000133
Saving checkpoint... 
Iteration: 1403761667, states[0] = 29.770979, states[40]= 0.000322
Saving checkpoint... 
Iteration: 1413974657, states[0] = -84.426997, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422877519, states[0] = -63.323248, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1430813514, states[0] = 4.133349, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1440804321, states[0] = 10.109778, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1452568166, states[0] = -83.373713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462622686, states[0] = -84.312010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471717603, states[0] = -84.650759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481152664, states[0] = 1.872986, states[40]= 0.000230
Saving checkpoint... 
Iteration: 1491196643, states[0] = -43.371016, states[40]= 0.000065
Total time: 3000150.000000
State Variables:
 - v in component membrane (millivolt): -84.562896
 - CaMKt in component CaMK (millimolar): 0.038975
 - cass in component intracellular_ions (millimolar): 0.000104
 - nai in component intracellular_ions (millimolar): 6.827341
 - nass in component intracellular_ions (millimolar): 6.827496
 - ki in component intracellular_ions (millimolar): 144.835438
 - kss in component intracellular_ions (millimolar): 144.835410
 - cansr in component intracellular_ions (millimolar): 2.054280
 - cajsr in component intracellular_ions (millimolar): 1.808672
 - cai in component intracellular_ions (millimolar): 0.000105
 - m in component INa (dimensionless): 0.010245
 - hf in component INa (dimensionless): 0.572883
 - hs in component INa (dimensionless): 0.572731
 - j in component INa (dimensionless): 0.571900
 - hsp in component INa (dimensionless): 0.325822
 - jp in component INa (dimensionless): 0.571213
 - mL in component INaL (dimensionless): 0.000353
 - hL in component INaL (dimensionless): 0.346267
 - hLp in component INaL (dimensionless): 0.150904
 - a in component Ito (dimensionless): 0.001252
 - iF in component Ito (dimensionless): 0.999203
 - iS in component Ito (dimensionless): 0.365534
 - ap in component Ito (dimensionless): 0.000638
 - iFp in component Ito (dimensionless): 0.999203
 - iSp in component Ito (dimensionless): 0.399851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.842702
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.995727
 - jca in component ICaL (dimensionless): 0.998108
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.005906
 - xrf in component IKr (dimensionless): 0.000408
 - xrs in component IKr (dimensionless): 0.674110
 - xs1 in component IKs (dimensionless): 0.386130
 - xs2 in component IKs (dimensionless): 0.000281
 - xk1 in component IK1 (dimensionless): 0.996786
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:06:13 (13039): called boinc_finish(0)

</stderr_txt>
]]>


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