𝕏

Task 56073495

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_400-conf_287_0
Workunit 26628992
Created 4 Jul 2024, 18:53:17 UTC
Sent 4 Jul 2024, 20:16:10 UTC
Report deadline 7 Jul 2024, 20:16:10 UTC
Received 7 Jul 2024, 11:25:07 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 11 sec
CPU time 37 min 50 sec
Validate state Valid
Credit 44.54
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.61 MB
Peak swap size 391.75 GB
Peak disk usage 0.15 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_400-conf_287.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_400-conf_287_0_r2090972258_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_400-conf_287_0_r2090972258_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.137293
     * GNaL_b in INaL: 0.005868
     * Gto_b in Ito: 0.084105
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031858
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163389
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.549336
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032136
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 7500.000000
     * CL_0 in membrane: 400.000000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499800000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 10567330, states[0] = -84.752021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20684126, states[0] = -14.471093, states[40]= 0.000525
Saving checkpoint... 
Iteration: 30308933, states[0] = -46.700535, states[40]= 0.000105
Saving checkpoint... 
Iteration: 41365411, states[0] = -84.672243, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51833986, states[0] = 24.361519, states[40]= 0.000013
Saving checkpoint... 
Iteration: 61282141, states[0] = -13.963336, states[40]= 0.000244
Saving checkpoint... 
Iteration: 71021061, states[0] = 29.741457, states[40]= 0.001176
Saving checkpoint... 
Iteration: 81451556, states[0] = 14.080796, states[40]= 0.000017
Saving checkpoint... 
Iteration: 90579494, states[0] = -84.846942, states[40]= 0.000001
Saving checkpoint... 
Iteration: 98946462, states[0] = -84.390094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 108519594, states[0] = -63.146064, states[40]= 0.000013
Saving checkpoint... 
Iteration: 118369968, states[0] = -84.764774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128065955, states[0] = 3.511174, states[40]= 0.000114
Saving checkpoint... 
Iteration: 138191116, states[0] = -84.942514, states[40]= 0.000001
Saving checkpoint... 
Iteration: 147694514, states[0] = -31.246200, states[40]= 0.000193
Saving checkpoint... 
Iteration: 158056487, states[0] = 10.679176, states[40]= 0.000033
Saving checkpoint... 
Iteration: 166216885, states[0] = 30.525283, states[40]= 0.005357
Saving checkpoint... 
Iteration: 175954909, states[0] = -84.590705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184648126, states[0] = 16.123382, states[40]= 0.000009
Saving checkpoint... 
Iteration: 195619288, states[0] = 30.102263, states[40]= 0.002224
Saving checkpoint... 
Iteration: 205360814, states[0] = -84.665741, states[40]= 0.000001
Saving checkpoint... 
Iteration: 215463747, states[0] = 5.293047, states[40]= 0.000087
Saving checkpoint... 
Iteration: 225275088, states[0] = -5.625768, states[40]= 0.000231
Saving checkpoint... 
Iteration: 233164560, states[0] = -84.706584, states[40]= 0.000001
Saving checkpoint... 
Iteration: 242012445, states[0] = 30.475237, states[40]= 0.027600
Saving checkpoint... 
Iteration: 251710771, states[0] = -51.717504, states[40]= 0.000046
Saving checkpoint... 
Iteration: 260591669, states[0] = -84.941945, states[40]= 0.000001
Saving checkpoint... 
Iteration: 268830490, states[0] = 25.853738, states[40]= 0.000040
Saving checkpoint... 
Iteration: 278976517, states[0] = -84.821596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 290056103, states[0] = 10.938629, states[40]= 0.000031
Saving checkpoint... 
Iteration: 301081589, states[0] = -14.067778, states[40]= 0.000209
Saving checkpoint... 
Iteration: 310537107, states[0] = -83.136355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317650939, states[0] = 14.359544, states[40]= 0.000014
Saving checkpoint... 
Iteration: 328303701, states[0] = -42.849909, states[40]= 0.000105
Saving checkpoint... 
Iteration: 336631138, states[0] = 25.542317, states[40]= 0.000032
Saving checkpoint... 
Iteration: 346728922, states[0] = -76.685973, states[40]= 0.000002
Saving checkpoint... 
Iteration: 355614979, states[0] = 30.652105, states[40]= 0.010800
Saving checkpoint... 
Iteration: 366472795, states[0] = -3.023774, states[40]= 0.000209
Saving checkpoint... 
Iteration: 376645408, states[0] = 17.770500, states[40]= 0.000006
Saving checkpoint... 
Iteration: 386647087, states[0] = 16.760610, states[40]= 0.000008
Saving checkpoint... 
Iteration: 396934125, states[0] = -81.719132, states[40]= 0.000001
Saving checkpoint... 
Iteration: 406166167, states[0] = -84.714837, states[40]= 0.000001
Saving checkpoint... 
Iteration: 415695513, states[0] = -32.546877, states[40]= 0.000187
Saving checkpoint... 
Iteration: 423034808, states[0] = 23.694230, states[40]= 0.000009
Saving checkpoint... 
Iteration: 432344092, states[0] = -84.265229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444015473, states[0] = 30.640532, states[40]= 0.009000
Saving checkpoint... 
Iteration: 453364149, states[0] = -84.690728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 463260439, states[0] = 7.845578, states[40]= 0.000057
Saving checkpoint... 
Iteration: 473243613, states[0] = 18.830127, states[40]= 0.000004
Saving checkpoint... 
Iteration: 482825484, states[0] = 28.084475, states[40]= 0.000236
Saving checkpoint... 
Iteration: 492642403, states[0] = 19.530857, states[40]= 0.000004
Saving checkpoint... 
Iteration: 501317135, states[0] = -59.958519, states[40]= 0.000019
Saving checkpoint... 
Iteration: 511690104, states[0] = -25.545598, states[40]= 0.000190
Saving checkpoint... 
Iteration: 522791781, states[0] = -84.929308, states[40]= 0.000001
Saving checkpoint... 
Iteration: 533056867, states[0] = 10.415641, states[40]= 0.000035
Saving checkpoint... 
Iteration: 543297898, states[0] = -35.563248, states[40]= 0.000168
Saving checkpoint... 
Iteration: 553349562, states[0] = -84.473547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562694503, states[0] = -31.245515, states[40]= 0.000192
Saving checkpoint... 
Iteration: 572490000, states[0] = -25.404730, states[40]= 0.000190
Saving checkpoint... 
Iteration: 580503838, states[0] = -43.001745, states[40]= 0.000103
Saving checkpoint... 
Iteration: 592483496, states[0] = -16.660872, states[40]= 0.000193
Saving checkpoint... 
Iteration: 601832140, states[0] = 25.055332, states[40]= 0.000022
Saving checkpoint... 
Iteration: 612313619, states[0] = -55.323620, states[40]= 0.000031
Saving checkpoint... 
Iteration: 621592260, states[0] = -84.927556, states[40]= 0.000001
Saving checkpoint... 
Iteration: 631274976, states[0] = -5.473587, states[40]= 0.000230
Saving checkpoint... 
Iteration: 640680741, states[0] = -12.888516, states[40]= 0.000217
Saving checkpoint... 
Iteration: 649339106, states[0] = -83.643091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659370881, states[0] = -84.749477, states[40]= 0.000001
Saving checkpoint... 
Iteration: 669774742, states[0] = -84.785418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 680072570, states[0] = -2.767235, states[40]= 0.000205
Saving checkpoint... 
Iteration: 688962193, states[0] = -84.656655, states[40]= 0.000001
Saving checkpoint... 
Iteration: 698601002, states[0] = 34.680968, states[40]= 0.612411
Saving checkpoint... 
Iteration: 707451942, states[0] = 13.723453, states[40]= 0.000017
Saving checkpoint... 
Iteration: 717326488, states[0] = -73.291123, states[40]= 0.000003
Saving checkpoint... 
Iteration: 725177810, states[0] = -84.809973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 736676391, states[0] = -7.179906, states[40]= 0.000237
Saving checkpoint... 
Iteration: 747388788, states[0] = -84.896499, states[40]= 0.000001
Saving checkpoint... 
Iteration: 757896749, states[0] = -34.094243, states[40]= 0.000178
Saving checkpoint... 
Iteration: 767894389, states[0] = -31.084949, states[40]= 0.000192
Saving checkpoint... 
Iteration: 778356073, states[0] = -84.576077, states[40]= 0.000001
Saving checkpoint... 
Iteration: 787132235, states[0] = -80.241110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796890608, states[0] = -26.186609, states[40]= 0.000192
Saving checkpoint... 
Iteration: 805779438, states[0] = -84.819827, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814250100, states[0] = 14.903609, states[40]= 0.000012
Saving checkpoint... 
Iteration: 823744656, states[0] = -84.276464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834825156, states[0] = 28.222854, states[40]= 0.000266
Saving checkpoint... 
Iteration: 844888752, states[0] = -23.738677, states[40]= 0.000185
Saving checkpoint... 
Iteration: 854448842, states[0] = 15.692458, states[40]= 0.000010
Saving checkpoint... 
Iteration: 865381163, states[0] = -84.831206, states[40]= 0.000001
Saving checkpoint... 
Iteration: 874881673, states[0] = -14.144249, states[40]= 0.000208
Saving checkpoint... 
Iteration: 885264006, states[0] = 5.104629, states[40]= 0.000089
Saving checkpoint... 
Iteration: 895313820, states[0] = -55.556372, states[40]= 0.000031
Saving checkpoint... 
Iteration: 904451608, states[0] = 13.943678, states[40]= 0.000016
Saving checkpoint... 
Iteration: 915965297, states[0] = -84.679123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 925540205, states[0] = -83.825847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935774489, states[0] = -84.769354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 945344883, states[0] = -84.282128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954864334, states[0] = 4.842192, states[40]= 0.000093
Saving checkpoint... 
Iteration: 965482815, states[0] = -15.702269, states[40]= 0.000198
Saving checkpoint... 
Iteration: 976185294, states[0] = -84.858517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 986147729, states[0] = -84.399295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995909407, states[0] = -49.933712, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1006002151, states[0] = 35.556471, states[40]= 1.112052
Saving checkpoint... 
Iteration: 1015511002, states[0] = -51.944515, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1025689089, states[0] = -24.172276, states[40]= 0.000186
Saving checkpoint... 
Iteration: 1035757106, states[0] = -84.576541, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1046537477, states[0] = -83.191632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056317340, states[0] = -60.174779, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1066764649, states[0] = -84.664299, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076315836, states[0] = -58.169056, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1085381618, states[0] = -84.823625, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1094333974, states[0] = -81.540551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1103809729, states[0] = 29.840376, states[40]= 0.075514
Saving checkpoint... 
Iteration: 1113726547, states[0] = -73.314342, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1125343748, states[0] = -84.200682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136426355, states[0] = 27.738409, states[40]= 0.000173
Saving checkpoint... 
Iteration: 1146388450, states[0] = -84.873548, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156513274, states[0] = -54.828375, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1166091533, states[0] = -27.368340, states[40]= 0.000194
Saving checkpoint... 
Iteration: 1175653877, states[0] = 12.465239, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1185964161, states[0] = -84.652781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1196074511, states[0] = -4.900999, states[40]= 0.000226
Saving checkpoint... 
Iteration: 1207162450, states[0] = -84.632602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216515637, states[0] = -57.892718, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1226446161, states[0] = 17.338300, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1234675544, states[0] = -6.117279, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1242354581, states[0] = -84.530211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250137296, states[0] = -83.116232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261530618, states[0] = -78.569615, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1270842462, states[0] = 19.513240, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1281350505, states[0] = -84.455784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291806617, states[0] = 29.003417, states[40]= 0.235739
Saving checkpoint... 
Iteration: 1301824590, states[0] = 28.453660, states[40]= 0.000326
Saving checkpoint... 
Iteration: 1313078734, states[0] = -10.150864, states[40]= 0.000232
Saving checkpoint... 
Iteration: 1322981104, states[0] = -84.807153, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1332755915, states[0] = -84.544779, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1340183246, states[0] = -84.823699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1348437402, states[0] = 22.337077, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1357766298, states[0] = -84.666826, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369549439, states[0] = -84.426409, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1380657204, states[0] = 10.201696, states[40]= 0.000036
Saving checkpoint... 
Iteration: 1391034583, states[0] = 23.830835, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1401604296, states[0] = 30.298062, states[40]= 0.536544
Saving checkpoint... 
Iteration: 1409872691, states[0] = -2.862712, states[40]= 0.000206
Saving checkpoint... 
Iteration: 1419566246, states[0] = -84.663069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1429585115, states[0] = -84.833825, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1439297882, states[0] = -35.478772, states[40]= 0.000168
Saving checkpoint... 
Iteration: 1450478913, states[0] = -10.378858, states[40]= 0.000231
Saving checkpoint... 
Iteration: 1460571986, states[0] = -84.718700, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1471972345, states[0] = -84.721545, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1481911554, states[0] = -52.603144, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1490861249, states[0] = 7.267629, states[40]= 0.000063
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -84.808400
 - CaMKt in component CaMK (millimolar): 0.148312
 - cass in component intracellular_ions (millimolar): 0.000143
 - nai in component intracellular_ions (millimolar): 7.143210
 - nass in component intracellular_ions (millimolar): 7.143477
 - ki in component intracellular_ions (millimolar): 144.129772
 - kss in component intracellular_ions (millimolar): 144.129738
 - cansr in component intracellular_ions (millimolar): 2.939070
 - cajsr in component intracellular_ions (millimolar): 1.952905
 - cai in component intracellular_ions (millimolar): 0.000137
 - m in component INa (dimensionless): 0.009996
 - hf in component INa (dimensionless): 0.582718
 - hs in component INa (dimensionless): 0.582061
 - j in component INa (dimensionless): 0.574246
 - hsp in component INa (dimensionless): 0.333114
 - jp in component INa (dimensionless): 0.557362
 - mL in component INaL (dimensionless): 0.000337
 - hL in component INaL (dimensionless): 0.236668
 - hLp in component INaL (dimensionless): 0.097308
 - a in component Ito (dimensionless): 0.001231
 - iF in component Ito (dimensionless): 0.999234
 - iS in component Ito (dimensionless): 0.180348
 - ap in component Ito (dimensionless): 0.000627
 - iFp in component Ito (dimensionless): 0.999234
 - iSp in component Ito (dimensionless): 0.200851
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.725114
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.957371
 - jca in component ICaL (dimensionless): 0.956777
 - ffp in component ICaL (dimensionless): 0.999936
 - fcafp in component ICaL (dimensionless): 0.999997
 - nca in component ICaL (dimensionless): 0.020388
 - xrf in component IKr (dimensionless): 0.036271
 - xrs in component IKr (dimensionless): 0.833346
 - xs1 in component IKs (dimensionless): 0.525102
 - xs2 in component IKs (dimensionless): 0.001507
 - xk1 in component IK1 (dimensionless): 0.996734
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
07:24:52 (11565): called boinc_finish(0)

</stderr_txt>
]]>


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