𝕏

Task 56073491

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_987_0
Workunit 26628990
Created 4 Jul 2024, 18:53:17 UTC
Sent 4 Jul 2024, 20:16:10 UTC
Report deadline 7 Jul 2024, 20:16:10 UTC
Received 7 Jul 2024, 7:20:03 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 223892
Run time 41 min 26 sec
CPU time 37 min 12 sec
Validate state Valid
Credit 44.24
Device peak FLOPS 5.05 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.47 MB
Peak swap size 391.75 GB
Peak disk usage 0.13 MB

Stderr output

<core_client_version>7.20.4</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_987.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_987_0_r1712215887_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_987_0_r1712215887_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.539952
     * GNaL_b in INaL: 0.005760
     * Gto_b in Ito: 0.083670
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031956
     * GKs_b in IKs: 0.001923
     * GK1_b in IK1: 0.163016
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.378912
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032556
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 8920734, states[0] = -29.579437, states[40]= 0.001036
Saving checkpoint... 
Iteration: 19017313, states[0] = 29.297557, states[40]= 0.002273
Saving checkpoint... 
Iteration: 27715882, states[0] = 11.949227, states[40]= 0.000079
Saving checkpoint... 
Iteration: 38926364, states[0] = -40.886254, states[40]= 0.000249
Saving checkpoint... 
Iteration: 49288076, states[0] = -81.188294, states[40]= 0.000002
Saving checkpoint... 
Iteration: 60042703, states[0] = 13.663412, states[40]= 0.000025
Saving checkpoint... 
Iteration: 69309650, states[0] = -84.838452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79307775, states[0] = -84.833756, states[40]= 0.000001
Saving checkpoint... 
Iteration: 89392069, states[0] = -2.741216, states[40]= 0.000301
Saving checkpoint... 
Iteration: 98837401, states[0] = 29.539581, states[40]= 0.015514
Saving checkpoint... 
Iteration: 109728060, states[0] = -8.870236, states[40]= 0.000342
Saving checkpoint... 
Iteration: 120934016, states[0] = -64.849743, states[40]= 0.000018
Saving checkpoint... 
Iteration: 131680456, states[0] = 26.024579, states[40]= 0.000138
Saving checkpoint... 
Iteration: 142359713, states[0] = 18.591044, states[40]= 0.000006
Saving checkpoint... 
Iteration: 151066617, states[0] = -22.558726, states[40]= 0.000260
Saving checkpoint... 
Iteration: 159907040, states[0] = -33.668114, states[40]= 0.000265
Saving checkpoint... 
Iteration: 167690754, states[0] = 18.440198, states[40]= 0.000006
Saving checkpoint... 
Iteration: 177240246, states[0] = -35.847156, states[40]= 0.000245
Saving checkpoint... 
Iteration: 184593895, states[0] = -64.364067, states[40]= 0.000019
Saving checkpoint... 
Iteration: 194995364, states[0] = 29.506285, states[40]= 0.011062
Saving checkpoint... 
Iteration: 205931062, states[0] = -73.427091, states[40]= 0.000006
Saving checkpoint... 
Iteration: 215908973, states[0] = -43.744926, states[40]= 0.000152
Saving checkpoint... 
Iteration: 226942987, states[0] = -84.163054, states[40]= 0.000001
Saving checkpoint... 
Iteration: 235552413, states[0] = -14.205527, states[40]= 0.000295
Saving checkpoint... 
Iteration: 243662069, states[0] = 28.730206, states[40]= 0.001833
Saving checkpoint... 
Iteration: 253416159, states[0] = -58.379591, states[40]= 0.000038
Saving checkpoint... 
Iteration: 263424524, states[0] = -72.244667, states[40]= 0.000007
Saving checkpoint... 
Iteration: 272753459, states[0] = -66.923774, states[40]= 0.000014
Saving checkpoint... 
Iteration: 282942321, states[0] = -84.569753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293236824, states[0] = -46.714489, states[40]= 0.000119
Saving checkpoint... 
Iteration: 304245342, states[0] = -59.684111, states[40]= 0.000033
Saving checkpoint... 
Iteration: 314164560, states[0] = 24.884913, states[40]= 0.000060
Saving checkpoint... 
Iteration: 324077785, states[0] = -61.221098, states[40]= 0.000028
Saving checkpoint... 
Iteration: 333348309, states[0] = 13.628149, states[40]= 0.000020
Saving checkpoint... 
Iteration: 343140684, states[0] = 28.472179, states[40]= 0.124751
Saving checkpoint... 
Iteration: 351281486, states[0] = -84.847947, states[40]= 0.000001
Saving checkpoint... 
Iteration: 360171159, states[0] = 18.648457, states[40]= 0.000005
Saving checkpoint... 
Iteration: 371540581, states[0] = -16.796463, states[40]= 0.000273
Saving checkpoint... 
Iteration: 381196263, states[0] = -3.022505, states[40]= 0.000287
Saving checkpoint... 
Iteration: 389606975, states[0] = -84.786543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 399118308, states[0] = -84.946611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 408484883, states[0] = 26.567071, states[40]= 0.000213
Saving checkpoint... 
Iteration: 415830121, states[0] = 19.930361, states[40]= 0.000005
Saving checkpoint... 
Iteration: 425466407, states[0] = 28.639792, states[40]= 0.099124
Saving checkpoint... 
Iteration: 433511126, states[0] = 9.197921, states[40]= 0.000055
Saving checkpoint... 
Iteration: 443771476, states[0] = -84.831695, states[40]= 0.000001
Saving checkpoint... 
Iteration: 453116998, states[0] = -84.987697, states[40]= 0.000001
Saving checkpoint... 
Iteration: 464455423, states[0] = 35.076410, states[40]= 1.182252
Saving checkpoint... 
Iteration: 475042416, states[0] = -33.972380, states[40]= 0.000261
Saving checkpoint... 
Iteration: 484620697, states[0] = 33.868130, states[40]= 0.987022
Saving checkpoint... 
Iteration: 493941806, states[0] = -84.936792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 503533022, states[0] = -24.924902, states[40]= 0.000267
Saving checkpoint... 
Iteration: 513576941, states[0] = -83.158390, states[40]= 0.000001
Saving checkpoint... 
Iteration: 524523723, states[0] = -14.492996, states[40]= 0.000292
Saving checkpoint... 
Iteration: 533915267, states[0] = -84.440602, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543598607, states[0] = -84.875478, states[40]= 0.000001
Saving checkpoint... 
Iteration: 554424635, states[0] = -84.789181, states[40]= 0.000001
Saving checkpoint... 
Iteration: 564782909, states[0] = 28.235028, states[40]= 0.285075
Saving checkpoint... 
Iteration: 574337448, states[0] = 3.332034, states[40]= 0.000152
Saving checkpoint... 
Iteration: 583777771, states[0] = 33.015124, states[40]= 0.884753
Saving checkpoint... 
Iteration: 592714349, states[0] = -56.674309, states[40]= 0.000045
Saving checkpoint... 
Iteration: 601474708, states[0] = 21.954512, states[40]= 0.000010
Saving checkpoint... 
Iteration: 611116025, states[0] = 29.037890, states[40]= 0.056414
Saving checkpoint... 
Iteration: 621894265, states[0] = -79.627231, states[40]= 0.000002
Saving checkpoint... 
Iteration: 631565013, states[0] = -83.095293, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641335171, states[0] = -1.051269, states[40]= 0.000249
Saving checkpoint... 
Iteration: 652140033, states[0] = 19.811164, states[40]= 0.000005
Saving checkpoint... 
Iteration: 662268859, states[0] = 35.145368, states[40]= 1.200365
Saving checkpoint... 
Iteration: 672248392, states[0] = -84.814240, states[40]= 0.000001
Saving checkpoint... 
Iteration: 682102719, states[0] = 29.643381, states[40]= 0.536357
Saving checkpoint... 
Iteration: 693694221, states[0] = -43.308366, states[40]= 0.000157
Saving checkpoint... 
Iteration: 704427907, states[0] = -85.000027, states[40]= 0.000001
Saving checkpoint... 
Iteration: 713886174, states[0] = -80.668083, states[40]= 0.000002
Saving checkpoint... 
Iteration: 723518264, states[0] = -34.896341, states[40]= 0.000253
Saving checkpoint... 
Iteration: 733441873, states[0] = 29.500817, states[40]= 0.009680
Saving checkpoint... 
Iteration: 743619046, states[0] = 26.121388, states[40]= 0.000148
Saving checkpoint... 
Iteration: 753347102, states[0] = -32.844025, states[40]= 0.000269
Saving checkpoint... 
Iteration: 763413965, states[0] = -84.910016, states[40]= 0.000001
Saving checkpoint... 
Iteration: 772862136, states[0] = -55.479913, states[40]= 0.000052
Saving checkpoint... 
Iteration: 782364271, states[0] = -59.730229, states[40]= 0.000033
Saving checkpoint... 
Iteration: 792312084, states[0] = 6.431038, states[40]= 0.000093
Saving checkpoint... 
Iteration: 803886360, states[0] = -84.252677, states[40]= 0.000001
Saving checkpoint... 
Iteration: 814211526, states[0] = -82.151794, states[40]= 0.000001
Saving checkpoint... 
Iteration: 823974141, states[0] = 7.602050, states[40]= 0.000075
Saving checkpoint... 
Iteration: 833752862, states[0] = 32.754765, states[40]= 0.857133
Saving checkpoint... 
Iteration: 842608222, states[0] = 26.538003, states[40]= 0.000206
Saving checkpoint... 
Iteration: 851296040, states[0] = 13.962607, states[40]= 0.000018
Saving checkpoint... 
Iteration: 859871568, states[0] = -80.640192, states[40]= 0.000002
Saving checkpoint... 
Iteration: 868858687, states[0] = -64.122823, states[40]= 0.000020
Saving checkpoint... 
Iteration: 877471156, states[0] = 5.664012, states[40]= 0.000106
Saving checkpoint... 
Iteration: 888696867, states[0] = -74.428279, states[40]= 0.000005
Saving checkpoint... 
Iteration: 899158325, states[0] = -22.337034, states[40]= 0.000258
Saving checkpoint... 
Iteration: 907941919, states[0] = 23.133573, states[40]= 0.000019
Saving checkpoint... 
Iteration: 915635218, states[0] = 4.623529, states[40]= 0.000126
Saving checkpoint... 
Iteration: 926294360, states[0] = 9.829380, states[40]= 0.000048
Saving checkpoint... 
Iteration: 935231406, states[0] = -84.914172, states[40]= 0.000001
Saving checkpoint... 
Iteration: 944103072, states[0] = 24.134709, states[40]= 0.000035
Saving checkpoint... 
Iteration: 952796455, states[0] = 6.087332, states[40]= 0.000099
Saving checkpoint... 
Iteration: 962475949, states[0] = -8.738537, states[40]= 0.000331
Saving checkpoint... 
Iteration: 973604712, states[0] = 21.651173, states[40]= 0.000008
Saving checkpoint... 
Iteration: 983373021, states[0] = -84.555800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992773917, states[0] = 19.053059, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1002964706, states[0] = -0.011507, states[40]= 0.000226
Saving checkpoint... 
Iteration: 1011740519, states[0] = 28.486074, states[40]= 0.123003
Saving checkpoint... 
Iteration: 1021211644, states[0] = -84.765495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1031547813, states[0] = -84.819543, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042230966, states[0] = 35.034579, states[40]= 1.182864
Saving checkpoint... 
Iteration: 1052337037, states[0] = -59.380528, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1062572843, states[0] = 29.404772, states[40]= 0.027106
Saving checkpoint... 
Iteration: 1072265066, states[0] = 19.590961, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1081899763, states[0] = 28.384640, states[40]= 0.142750
Saving checkpoint... 
Iteration: 1092485572, states[0] = -40.491304, states[40]= 0.000190
Saving checkpoint... 
Iteration: 1101484889, states[0] = -40.791961, states[40]= 0.000188
Saving checkpoint... 
Iteration: 1109671823, states[0] = -69.940362, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1121240307, states[0] = 28.918658, states[40]= 0.002328
Saving checkpoint... 
Iteration: 1130998020, states[0] = -62.469148, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1140793747, states[0] = -11.995713, states[40]= 0.000313
Saving checkpoint... 
Iteration: 1151026849, states[0] = -84.663850, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161113593, states[0] = 1.954278, states[40]= 0.000182
Saving checkpoint... 
Iteration: 1170841817, states[0] = -81.648571, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1181026348, states[0] = -84.712157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1190718462, states[0] = 29.723692, states[40]= 0.546695
Saving checkpoint... 
Iteration: 1201399390, states[0] = 28.809238, states[40]= 0.001989
Saving checkpoint... 
Iteration: 1212987971, states[0] = -59.814911, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1223686689, states[0] = -84.668681, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1233338711, states[0] = -83.235951, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1242736410, states[0] = 25.849385, states[40]= 0.000119
Saving checkpoint... 
Iteration: 1252446994, states[0] = -8.780566, states[40]= 0.000330
Saving checkpoint... 
Iteration: 1262153866, states[0] = -65.811241, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1272788809, states[0] = -23.995532, states[40]= 0.000262
Saving checkpoint... 
Iteration: 1282448750, states[0] = -15.649229, states[40]= 0.000280
Saving checkpoint... 
Iteration: 1290741529, states[0] = 20.591357, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1301310566, states[0] = -57.162979, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1311555237, states[0] = 28.761268, states[40]= 0.001851
Saving checkpoint... 
Iteration: 1318622211, states[0] = -30.485087, states[40]= 0.000277
Saving checkpoint... 
Iteration: 1327497094, states[0] = -83.575199, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1336740321, states[0] = 18.573035, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1345432605, states[0] = -2.325065, states[40]= 0.000273
Saving checkpoint... 
Iteration: 1354731828, states[0] = 22.457300, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1366736980, states[0] = 18.781941, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1374862826, states[0] = -44.484302, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1385209691, states[0] = 29.525186, states[40]= 0.010931
Saving checkpoint... 
Iteration: 1394521322, states[0] = -84.913717, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1402872631, states[0] = 29.463463, states[40]= 0.022595
Saving checkpoint... 
Iteration: 1412155244, states[0] = -83.554177, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1422424999, states[0] = -2.430139, states[40]= 0.000276
Saving checkpoint... 
Iteration: 1432695080, states[0] = 28.721309, states[40]= 0.410066
Saving checkpoint... 
Iteration: 1444407883, states[0] = 10.825639, states[40]= 0.000039
Saving checkpoint... 
Iteration: 1454127182, states[0] = -55.197631, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1463001111, states[0] = -84.742800, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472949182, states[0] = -42.657527, states[40]= 0.000164
Saving checkpoint... 
Iteration: 1482520614, states[0] = 34.442896, states[40]= 1.079828
Saving checkpoint... 
Iteration: 1490974355, states[0] = -79.831300, states[40]= 0.000002
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.843106
 - CaMKt in component CaMK (millimolar): 0.216641
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.282750
 - nass in component intracellular_ions (millimolar): 7.283103
 - ki in component intracellular_ions (millimolar): 143.837490
 - kss in component intracellular_ions (millimolar): 143.837455
 - cansr in component intracellular_ions (millimolar): 3.333452
 - cajsr in component intracellular_ions (millimolar): 1.924418
 - cai in component intracellular_ions (millimolar): 0.000161
 - m in component INa (dimensionless): 0.009961
 - hf in component INa (dimensionless): 0.584098
 - hs in component INa (dimensionless): 0.583043
 - j in component INa (dimensionless): 0.553536
 - hsp in component INa (dimensionless): 0.331557
 - jp in component INa (dimensionless): 0.511902
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.183215
 - hLp in component INaL (dimensionless): 0.074737
 - a in component Ito (dimensionless): 0.001229
 - iF in component Ito (dimensionless): 0.999237
 - iS in component Ito (dimensionless): 0.131359
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999237
 - iSp in component Ito (dimensionless): 0.146878
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677833
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928957
 - jca in component ICaL (dimensionless): 0.911598
 - ffp in component ICaL (dimensionless): 0.998939
 - fcafp in component ICaL (dimensionless): 0.999940
 - nca in component ICaL (dimensionless): 0.041901
 - xrf in component IKr (dimensionless): 0.100561
 - xrs in component IKr (dimensionless): 0.872619
 - xs1 in component IKs (dimensionless): 0.570287
 - xs2 in component IKs (dimensionless): 0.007157
 - xk1 in component IK1 (dimensionless): 0.996737
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
03:19:52 (8058): called boinc_finish(0)

</stderr_txt>
]]>


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