𝕏

Task 56072640

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_686_0
Workunit 26628566
Created 4 Jul 2024, 18:52:51 UTC
Sent 4 Jul 2024, 20:11:01 UTC
Report deadline 7 Jul 2024, 20:11:01 UTC
Received 5 Jul 2024, 8:19:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239650
Run time 1 hours 40 min 41 sec
CPU time 1 hours 38 min 9 sec
Validate state Valid
Credit 43.13
Device peak FLOPS 4.09 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.68 MB
Peak disk usage 0.04 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_686.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_686_0_r743656684_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-TESZT_Block_Ks_95-conf_686_0_r743656684_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.949654
     * GNaL_b in INaL: 0.005783
     * Gto_b in Ito: 0.084315
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031898
     * GKs_b in IKs: 0.000096
     * GK1_b in IK1: 0.162831
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.312559
     * GKb_b in IKb: 0.003809
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032244
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 3924853, states[0] = -94.995772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 9555682, states[0] = 15.271054, states[40]= 0.004153
Saving checkpoint... 
Iteration: 15789118, states[0] = -94.796436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21781254, states[0] = -94.760439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27812076, states[0] = -94.797372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33573528, states[0] = 8.165717, states[40]= 0.004591
Saving checkpoint... 
Iteration: 37946984, states[0] = -94.887615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 41973301, states[0] = -94.893522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50772706, states[0] = -94.713018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56932944, states[0] = -94.875704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 62969182, states[0] = -94.886706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68842783, states[0] = -94.814439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77728542, states[0] = -94.586579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87129646, states[0] = -36.418834, states[40]= 0.000624
Saving checkpoint... 
Iteration: 96161795, states[0] = -70.997357, states[40]= 0.000003
Saving checkpoint... 
Iteration: 105561656, states[0] = 13.715425, states[40]= 0.003807
Saving checkpoint... 
Iteration: 114516127, states[0] = 27.819403, states[40]= 0.007139
Saving checkpoint... 
Iteration: 123918902, states[0] = -94.864104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 132683920, states[0] = -94.079135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141847239, states[0] = -94.814868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 151021191, states[0] = 27.175630, states[40]= 0.002381
Saving checkpoint... 
Iteration: 160308776, states[0] = -94.768909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169729385, states[0] = -94.586129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175886147, states[0] = -94.845300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185183860, states[0] = -94.068473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194578757, states[0] = 5.797174, states[40]= 0.004786
Saving checkpoint... 
Iteration: 203921167, states[0] = -94.864103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212975955, states[0] = -94.882994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222179668, states[0] = -93.229993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 231324162, states[0] = -94.788926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240751745, states[0] = -94.653837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249650947, states[0] = -57.916167, states[40]= 0.000029
Saving checkpoint... 
Iteration: 259048294, states[0] = 18.916616, states[40]= 0.002744
Saving checkpoint... 
Iteration: 268050026, states[0] = 18.278132, states[40]= 0.002878
Saving checkpoint... 
Iteration: 277137610, states[0] = -44.019822, states[40]= 0.000240
Saving checkpoint... 
Iteration: 286289248, states[0] = -94.736670, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295205691, states[0] = -94.495120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 304598016, states[0] = -7.002549, states[40]= 0.003419
Saving checkpoint... 
Iteration: 313512599, states[0] = 27.953579, states[40]= 0.020905
Saving checkpoint... 
Iteration: 322601939, states[0] = -10.462143, states[40]= 0.002616
Saving checkpoint... 
Iteration: 331420172, states[0] = -94.863081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340625073, states[0] = -31.987885, states[40]= 0.000965
Saving checkpoint... 
Iteration: 349889971, states[0] = -94.846871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359080508, states[0] = 4.859104, states[40]= 0.004822
Saving checkpoint... 
Iteration: 367847033, states[0] = -94.813317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376756463, states[0] = -94.665697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386148066, states[0] = -54.826766, states[40]= 0.000048
Saving checkpoint... 
Iteration: 395565963, states[0] = 11.912855, states[40]= 0.004132
Saving checkpoint... 
Iteration: 404701768, states[0] = -94.477318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414166560, states[0] = -77.881040, states[40]= 0.000001
Saving checkpoint... 
Iteration: 423408109, states[0] = -94.856863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 432893401, states[0] = -94.848639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442275676, states[0] = -94.709869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451405166, states[0] = -94.855212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460592471, states[0] = -2.632899, states[40]= 0.004320
Saving checkpoint... 
Iteration: 469716112, states[0] = -94.536493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479133091, states[0] = -39.571078, states[40]= 0.000430
Saving checkpoint... 
Iteration: 488168373, states[0] = -80.839534, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497165136, states[0] = -75.644235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 506194087, states[0] = -94.430628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 515380187, states[0] = -94.839839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 524517236, states[0] = 27.732664, states[40]= 0.005296
Saving checkpoint... 
Iteration: 533666627, states[0] = -77.986863, states[40]= 0.000001
Saving checkpoint... 
Iteration: 542065236, states[0] = 12.227941, states[40]= 0.004081
Saving checkpoint... 
Iteration: 551336822, states[0] = -94.802196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560361784, states[0] = -94.825771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569684138, states[0] = -94.093493, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579096962, states[0] = -6.120271, states[40]= 0.003622
Saving checkpoint... 
Iteration: 588247248, states[0] = -94.640000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597476276, states[0] = -94.881524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606933270, states[0] = -94.867606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615958159, states[0] = -94.876346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 625020971, states[0] = 27.218072, states[40]= 0.002459
Saving checkpoint... 
Iteration: 633647569, states[0] = -54.298464, states[40]= 0.000052
Saving checkpoint... 
Iteration: 642537464, states[0] = 22.724425, states[40]= 0.002016
Saving checkpoint... 
Iteration: 651678570, states[0] = -92.797702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 660868002, states[0] = -94.830371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670229047, states[0] = -94.582792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 679348602, states[0] = -94.813604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688760454, states[0] = -94.674489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698131967, states[0] = -38.486896, states[40]= 0.000491
Saving checkpoint... 
Iteration: 706729211, states[0] = -94.583210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715854732, states[0] = -94.819104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724559521, states[0] = 14.611745, states[40]= 0.003644
Saving checkpoint... 
Iteration: 733962796, states[0] = -94.877288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743102030, states[0] = -10.543599, states[40]= 0.002598
Saving checkpoint... 
Iteration: 752267284, states[0] = -94.690397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761144871, states[0] = -51.460386, states[40]= 0.000081
Saving checkpoint... 
Iteration: 770328205, states[0] = -94.791649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779459659, states[0] = -94.876171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788555165, states[0] = 16.333236, states[40]= 0.003292
Saving checkpoint... 
Iteration: 797780702, states[0] = -94.718631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 806667971, states[0] = -80.171689, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815662695, states[0] = -72.050501, states[40]= 0.000003
Saving checkpoint... 
Iteration: 824802058, states[0] = -94.755951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834115377, states[0] = -23.038850, states[40]= 0.001340
Saving checkpoint... 
Iteration: 842853516, states[0] = -94.817518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852184223, states[0] = -94.100262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861432911, states[0] = -94.866472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870865882, states[0] = -94.827887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879873527, states[0] = -94.833692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 889140293, states[0] = -46.728808, states[40]= 0.000164
Saving checkpoint... 
Iteration: 898383206, states[0] = -94.840387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907658404, states[0] = -66.423718, states[40]= 0.000007
Saving checkpoint... 
Iteration: 916785974, states[0] = -94.728232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925997812, states[0] = -94.885172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935447695, states[0] = -94.871686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944653903, states[0] = -61.163331, states[40]= 0.000017
Saving checkpoint... 
Iteration: 954161430, states[0] = -70.308198, states[40]= 0.000004
Saving checkpoint... 
Iteration: 963640873, states[0] = -47.321258, states[40]= 0.000151
Saving checkpoint... 
Iteration: 972829207, states[0] = -94.792032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981960133, states[0] = -94.875528, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990838786, states[0] = -94.802571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1000095103, states[0] = -4.622231, states[40]= 0.003948
Saving checkpoint... 
Iteration: 1009389613, states[0] = -94.844080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018544726, states[0] = 20.208658, states[40]= 0.002480
Saving checkpoint... 
Iteration: 1027840996, states[0] = -94.804726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036858864, states[0] = -94.821459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046258984, states[0] = -94.669447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1055308183, states[0] = -94.764277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064535085, states[0] = 23.506336, states[40]= 0.001891
Saving checkpoint... 
Iteration: 1073600656, states[0] = -9.300519, states[40]= 0.002879
Saving checkpoint... 
Iteration: 1082863080, states[0] = -94.824803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1092040634, states[0] = 21.647356, states[40]= 0.002205
Saving checkpoint... 
Iteration: 1101219055, states[0] = -94.545201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109986672, states[0] = -94.882052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119154566, states[0] = -61.909093, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1128620314, states[0] = -27.584397, states[40]= 0.001251
Saving checkpoint... 
Iteration: 1137487625, states[0] = -94.882163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1146643564, states[0] = -50.096432, states[40]= 0.000100
Saving checkpoint... 
Iteration: 1155613836, states[0] = -21.609933, states[40]= 0.001349
Saving checkpoint... 
Iteration: 1165063790, states[0] = 12.846752, states[40]= 0.003975
Saving checkpoint... 
Iteration: 1174453011, states[0] = -94.872540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183354243, states[0] = -94.816845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1192409836, states[0] = -94.854755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201696835, states[0] = -94.448163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210874061, states[0] = -94.832795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219622285, states[0] = -29.401263, states[40]= 0.001153
Saving checkpoint... 
Iteration: 1228687568, states[0] = -94.304947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237734422, states[0] = -94.598483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246919522, states[0] = -94.859221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255792103, states[0] = -94.737901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264712521, states[0] = -94.519304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1270836300, states[0] = -94.798827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277019761, states[0] = 27.416246, states[40]= 0.003008
Saving checkpoint... 
Iteration: 1284659794, states[0] = -68.160710, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1290438902, states[0] = -94.867135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296815684, states[0] = -94.773835, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301156816, states[0] = -64.508230, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1304221486, states[0] = -94.553439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1308544342, states[0] = 20.345997, states[40]= 0.002453
Saving checkpoint... 
Iteration: 1316011106, states[0] = 27.961028, states[40]= 0.033974
Saving checkpoint... 
Iteration: 1320064601, states[0] = 12.501777, states[40]= 0.004035
Saving checkpoint... 
Iteration: 1323701148, states[0] = -94.470766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1329620072, states[0] = -27.360840, states[40]= 0.001261
Saving checkpoint... 
Iteration: 1335413935, states[0] = -94.856235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341243852, states[0] = -94.627232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343824882, states[0] = -94.785431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348166155, states[0] = -77.223007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351033966, states[0] = 23.864298, states[40]= 0.001838
Saving checkpoint... 
Iteration: 1355648670, states[0] = -55.463145, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1358668084, states[0] = -80.349730, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1361446060, states[0] = -94.869462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367402163, states[0] = -94.850027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1370116239, states[0] = -23.832593, states[40]= 0.001336
Saving checkpoint... 
Iteration: 1376004426, states[0] = 32.600011, states[40]= 0.307314
Saving checkpoint... 
Iteration: 1381884700, states[0] = -94.839492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387888158, states[0] = -94.841694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393579127, states[0] = 5.605368, states[40]= 0.004796
Saving checkpoint... 
Iteration: 1399418954, states[0] = -94.858367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406398967, states[0] = -94.848094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412795457, states[0] = -94.743000, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422256166, states[0] = -94.660829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1431481448, states[0] = -94.879572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437390408, states[0] = -94.842908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446465089, states[0] = -94.875187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452598747, states[0] = -7.622979, states[40]= 0.003273
Saving checkpoint... 
Iteration: 1458666536, states[0] = -77.828354, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464921908, states[0] = -94.859457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471126254, states[0] = -33.083520, states[40]= 0.000879
Saving checkpoint... 
Iteration: 1477346454, states[0] = -94.808430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482633933, states[0] = -40.383708, states[40]= 0.000388
Saving checkpoint... 
Iteration: 1486620847, states[0] = -28.073909, states[40]= 0.001228
Saving checkpoint... 
Iteration: 1495539535, states[0] = 22.025580, states[40]= 0.002138
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.759258
 - CaMKt in component CaMK (millimolar): 0.012919
 - cass in component intracellular_ions (millimolar): 0.000087
 - nai in component intracellular_ions (millimolar): 6.733821
 - nass in component intracellular_ions (millimolar): 6.733917
 - ki in component intracellular_ions (millimolar): 145.147327
 - kss in component intracellular_ions (millimolar): 145.147307
 - cansr in component intracellular_ions (millimolar): 1.669772
 - cajsr in component intracellular_ions (millimolar): 1.627411
 - cai in component intracellular_ions (millimolar): 0.000089
 - m in component INa (dimensionless): 0.003671
 - hf in component INa (dimensionless): 0.877504
 - hs in component INa (dimensionless): 0.877496
 - j in component INa (dimensionless): 0.877445
 - hsp in component INa (dimensionless): 0.721123
 - jp in component INa (dimensionless): 0.877409
 - mL in component INaL (dimensionless): 0.000051
 - hL in component INaL (dimensionless): 0.702265
 - hLp in component INaL (dimensionless): 0.437078
 - a in component Ito (dimensionless): 0.000629
 - iF in component Ito (dimensionless): 0.999866
 - iS in component Ito (dimensionless): 0.606054
 - ap in component Ito (dimensionless): 0.000321
 - iFp in component Ito (dimensionless): 0.999866
 - iSp in component Ito (dimensionless): 0.675936
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.911874
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999813
 - jca in component ICaL (dimensionless): 0.999969
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003079
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.373099
 - xs1 in component IKs (dimensionless): 0.275971
 - xs2 in component IKs (dimensionless): 0.000089
 - xk1 in component IK1 (dimensionless): 0.997375
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
03:40:44 (197909): called boinc_finish(0)

</stderr_txt>
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