𝕏

Task 56067070

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_781_1
Workunit 26625807
Created 4 Jul 2024, 18:50:09 UTC
Sent 4 Jul 2024, 19:45:45 UTC
Report deadline 7 Jul 2024, 19:45:45 UTC
Received 5 Jul 2024, 1:32:54 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 239498
Run time 2 hours 7 min 28 sec
CPU time 2 hours 6 min 43 sec
Validate state Valid
Credit 45.19
Device peak FLOPS 2.71 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.24 MB
Peak swap size 6.32 MB
Peak disk usage 0.12 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_781_1_r1772719499_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Schmidt_333-conf_781_1_r1772719499_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000033.300000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.907402
     * GNaL_b in INaL: 0.005921
     * Gto_b in Ito: 0.084184
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031831
     * GKs_b in IKs: 0.001928
     * GK1_b in IK1: 0.163885
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.144059
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031821
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 9001.000000
     * CL_0 in membrane: 333.300000
     * cao in extracellular: 2.500000
     * ko in extracellular: 5.900000
     * nao in extracellular: 126.200000
Starting output configuration...
Output starts at iteration 1499850000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 6625054, states[0] = -82.624476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 16068002, states[0] = -2.544734, states[40]= 0.001377
Saving checkpoint... 
Iteration: 25471714, states[0] = -84.568205, states[40]= 0.000001
Saving checkpoint... 
Iteration: 34875021, states[0] = 16.410409, states[40]= 0.000019
Saving checkpoint... 
Iteration: 44253749, states[0] = -33.837542, states[40]= 0.000351
Saving checkpoint... 
Iteration: 53626484, states[0] = -83.784080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 63124393, states[0] = -83.599252, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72672996, states[0] = 29.572707, states[40]= 0.017702
Saving checkpoint... 
Iteration: 82114410, states[0] = -78.398388, states[40]= 0.000003
Saving checkpoint... 
Iteration: 91725324, states[0] = -2.805811, states[40]= 0.000301
Saving checkpoint... 
Iteration: 101185919, states[0] = 24.927705, states[40]= 0.000059
Saving checkpoint... 
Iteration: 110665344, states[0] = 28.844130, states[40]= 0.074145
Saving checkpoint... 
Iteration: 120273891, states[0] = -74.340559, states[40]= 0.000006
Saving checkpoint... 
Iteration: 129722227, states[0] = -3.805958, states[40]= 0.000304
Saving checkpoint... 
Iteration: 139262351, states[0] = -60.009962, states[40]= 0.000033
Saving checkpoint... 
Iteration: 148765077, states[0] = -65.378009, states[40]= 0.000018
Saving checkpoint... 
Iteration: 158294641, states[0] = -84.759617, states[40]= 0.000001
Saving checkpoint... 
Iteration: 167778648, states[0] = -83.291110, states[40]= 0.000001
Saving checkpoint... 
Iteration: 177365657, states[0] = 12.477662, states[40]= 0.000026
Saving checkpoint... 
Iteration: 186879827, states[0] = -0.111135, states[40]= 0.000229
Saving checkpoint... 
Iteration: 196305032, states[0] = -84.952704, states[40]= 0.000001
Saving checkpoint... 
Iteration: 205928327, states[0] = -68.908131, states[40]= 0.000011
Saving checkpoint... 
Iteration: 215505325, states[0] = 26.074543, states[40]= 0.000141
Saving checkpoint... 
Iteration: 224941403, states[0] = -83.811597, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234501006, states[0] = 27.125466, states[40]= 0.000336
Saving checkpoint... 
Iteration: 243999031, states[0] = 27.532279, states[40]= 0.000486
Saving checkpoint... 
Iteration: 250686798, states[0] = 15.747434, states[40]= 0.000011
Saving checkpoint... 
Iteration: 260117995, states[0] = -84.757815, states[40]= 0.000001
Saving checkpoint... 
Iteration: 269570902, states[0] = -44.277906, states[40]= 0.000149
Saving checkpoint... 
Iteration: 279015801, states[0] = 16.711112, states[40]= 0.000008
Saving checkpoint... 
Iteration: 288565276, states[0] = -39.354160, states[40]= 0.000210
Saving checkpoint... 
Iteration: 298049975, states[0] = -19.569758, states[40]= 0.000262
Saving checkpoint... 
Iteration: 307526242, states[0] = 7.295120, states[40]= 0.000079
Saving checkpoint... 
Iteration: 317080048, states[0] = -63.139461, states[40]= 0.000023
Saving checkpoint... 
Iteration: 326510464, states[0] = 17.080970, states[40]= 0.000007
Saving checkpoint... 
Iteration: 336053103, states[0] = -29.335880, states[40]= 0.000284
Saving checkpoint... 
Iteration: 345564325, states[0] = -45.623177, states[40]= 0.000134
Saving checkpoint... 
Iteration: 355051061, states[0] = -29.139553, states[40]= 0.000284
Saving checkpoint... 
Iteration: 364611588, states[0] = -84.816948, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374207619, states[0] = -17.513325, states[40]= 0.000269
Saving checkpoint... 
Iteration: 383595914, states[0] = -84.355007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 393053761, states[0] = -37.929602, states[40]= 0.000227
Saving checkpoint... 
Iteration: 402520836, states[0] = 3.833428, states[40]= 0.000141
Saving checkpoint... 
Iteration: 412011582, states[0] = 10.528421, states[40]= 0.000041
Saving checkpoint... 
Iteration: 421459216, states[0] = 34.953578, states[40]= 1.075061
Saving checkpoint... 
Iteration: 430968649, states[0] = 29.278408, states[40]= 0.035167
Saving checkpoint... 
Iteration: 440425583, states[0] = -84.500044, states[40]= 0.000001
Saving checkpoint... 
Iteration: 449912179, states[0] = -80.172904, states[40]= 0.000002
Saving checkpoint... 
Iteration: 459380301, states[0] = -37.710534, states[40]= 0.000230
Saving checkpoint... 
Iteration: 468897065, states[0] = -61.484896, states[40]= 0.000028
Saving checkpoint... 
Iteration: 478438077, states[0] = -84.871033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 487917059, states[0] = -84.144991, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497494575, states[0] = 16.316199, states[40]= 0.000009
Saving checkpoint... 
Iteration: 506989921, states[0] = 18.626398, states[40]= 0.000005
Saving checkpoint... 
Iteration: 516462177, states[0] = 29.499103, states[40]= 0.016232
Saving checkpoint... 
Iteration: 526094130, states[0] = -84.787173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 535665203, states[0] = 11.027582, states[40]= 0.000036
Saving checkpoint... 
Iteration: 545156068, states[0] = 16.576648, states[40]= 0.000009
Saving checkpoint... 
Iteration: 554787380, states[0] = 28.769644, states[40]= 0.080337
Saving checkpoint... 
Iteration: 564258804, states[0] = -84.812225, states[40]= 0.000001
Saving checkpoint... 
Iteration: 573892977, states[0] = -71.087360, states[40]= 0.000009
Saving checkpoint... 
Iteration: 583435634, states[0] = -84.958470, states[40]= 0.000001
Saving checkpoint... 
Iteration: 592978684, states[0] = 20.201144, states[40]= 0.000005
Saving checkpoint... 
Iteration: 602564461, states[0] = -80.944421, states[40]= 0.000002
Saving checkpoint... 
Iteration: 612198105, states[0] = -37.370434, states[40]= 0.000233
Saving checkpoint... 
Iteration: 621799893, states[0] = 25.200254, states[40]= 0.000073
Saving checkpoint... 
Iteration: 631502193, states[0] = -0.266392, states[40]= 0.000230
Saving checkpoint... 
Iteration: 641075278, states[0] = -84.621899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650567587, states[0] = -84.149928, states[40]= 0.000001
Saving checkpoint... 
Iteration: 660107968, states[0] = 28.213716, states[40]= 0.181422
Saving checkpoint... 
Iteration: 669695268, states[0] = -41.231090, states[40]= 0.000186
Saving checkpoint... 
Iteration: 679170736, states[0] = -8.295318, states[40]= 0.000333
Saving checkpoint... 
Iteration: 688693482, states[0] = -41.381636, states[40]= 0.000184
Saving checkpoint... 
Iteration: 698238395, states[0] = -84.678727, states[40]= 0.000001
Saving checkpoint... 
Iteration: 707806368, states[0] = 16.644830, states[40]= 0.000008
Saving checkpoint... 
Iteration: 717419414, states[0] = -84.918781, states[40]= 0.000001
Saving checkpoint... 
Iteration: 726944762, states[0] = 29.255172, states[40]= 0.004245
Saving checkpoint... 
Iteration: 736510323, states[0] = -25.510800, states[40]= 0.000273
Saving checkpoint... 
Iteration: 746098710, states[0] = 28.147485, states[40]= 0.230231
Saving checkpoint... 
Iteration: 755715905, states[0] = -80.992909, states[40]= 0.000002
Saving checkpoint... 
Iteration: 765385245, states[0] = -83.124842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 775009533, states[0] = -29.753365, states[40]= 0.000284
Saving checkpoint... 
Iteration: 784584650, states[0] = -84.971744, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794088280, states[0] = 33.548011, states[40]= 0.670341
Saving checkpoint... 
Iteration: 803561338, states[0] = -84.675317, states[40]= 0.000001
Saving checkpoint... 
Iteration: 813130744, states[0] = 15.634740, states[40]= 0.000011
Saving checkpoint... 
Iteration: 822706468, states[0] = -78.204378, states[40]= 0.000003
Saving checkpoint... 
Iteration: 832292339, states[0] = 17.640506, states[40]= 0.000007
Saving checkpoint... 
Iteration: 841931453, states[0] = 29.474391, states[40]= 0.008255
Saving checkpoint... 
Iteration: 851488012, states[0] = -9.914154, states[40]= 0.000328
Saving checkpoint... 
Iteration: 861038812, states[0] = -81.064260, states[40]= 0.000002
Saving checkpoint... 
Iteration: 870655740, states[0] = -14.210949, states[40]= 0.000295
Saving checkpoint... 
Iteration: 880252433, states[0] = 28.187010, states[40]= 0.193926
Saving checkpoint... 
Iteration: 889780299, states[0] = 21.381248, states[40]= 0.000007
Saving checkpoint... 
Iteration: 896613532, states[0] = 21.049106, states[40]= 0.000006
Saving checkpoint... 
Iteration: 906187177, states[0] = -62.163852, states[40]= 0.000025
Saving checkpoint... 
Iteration: 915765617, states[0] = 27.377340, states[40]= 0.000415
Saving checkpoint... 
Iteration: 925473693, states[0] = -1.212596, states[40]= 0.000252
Saving checkpoint... 
Iteration: 935077355, states[0] = 29.695451, states[40]= 0.549985
Saving checkpoint... 
Iteration: 944813938, states[0] = -12.670704, states[40]= 0.000309
Saving checkpoint... 
Iteration: 954406624, states[0] = 34.739354, states[40]= 1.130346
Saving checkpoint... 
Iteration: 964140647, states[0] = -6.151303, states[40]= 0.000324
Saving checkpoint... 
Iteration: 973717752, states[0] = -84.784823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 983360107, states[0] = -81.201043, states[40]= 0.000002
Saving checkpoint... 
Iteration: 993055536, states[0] = -84.866906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002671798, states[0] = -54.208202, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1012387803, states[0] = -84.876048, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1021983367, states[0] = -27.709849, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1031579796, states[0] = 29.420865, states[40]= 0.006512
Saving checkpoint... 
Iteration: 1041259625, states[0] = 24.370154, states[40]= 0.000040
Saving checkpoint... 
Iteration: 1050895453, states[0] = 24.976649, states[40]= 0.033957
Saving checkpoint... 
Iteration: 1060482385, states[0] = -31.641500, states[40]= 0.000278
Saving checkpoint... 
Iteration: 1070091959, states[0] = 23.389013, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1079791559, states[0] = -1.173907, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1088716122, states[0] = -84.901757, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098446514, states[0] = 7.823371, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1108102224, states[0] = 14.996672, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1117744701, states[0] = 27.656589, states[40]= 0.000537
Saving checkpoint... 
Iteration: 1127406684, states[0] = 28.845778, states[40]= 0.002064
Saving checkpoint... 
Iteration: 1136991726, states[0] = -54.233330, states[40]= 0.000060
Saving checkpoint... 
Iteration: 1146696239, states[0] = -84.706233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1156366052, states[0] = -84.771899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1166053120, states[0] = 32.276288, states[40]= 0.814472
Saving checkpoint... 
Iteration: 1175727802, states[0] = 29.338047, states[40]= 0.031375
Saving checkpoint... 
Iteration: 1185288298, states[0] = -10.366406, states[40]= 0.000325
Saving checkpoint... 
Iteration: 1194998008, states[0] = -71.714801, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1204648661, states[0] = -50.269640, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1214336496, states[0] = -80.754532, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1223957930, states[0] = -20.297870, states[40]= 0.000260
Saving checkpoint... 
Iteration: 1233553879, states[0] = 29.048341, states[40]= 0.054316
Saving checkpoint... 
Iteration: 1243213457, states[0] = 29.302426, states[40]= 0.503516
Saving checkpoint... 
Iteration: 1252784565, states[0] = -14.730709, states[40]= 0.000290
Saving checkpoint... 
Iteration: 1262395184, states[0] = 28.266221, states[40]= 0.000998
Saving checkpoint... 
Iteration: 1271984548, states[0] = -63.014676, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1281676261, states[0] = -84.517911, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1291333221, states[0] = -83.277579, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1300883005, states[0] = 29.465662, states[40]= 0.021196
Saving checkpoint... 
Iteration: 1310508036, states[0] = -84.568026, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1320157969, states[0] = -79.529749, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1329826707, states[0] = -82.029451, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1339432348, states[0] = -1.251911, states[40]= 0.000252
Saving checkpoint... 
Iteration: 1349032584, states[0] = 31.885687, states[40]= 0.371585
Saving checkpoint... 
Iteration: 1358712503, states[0] = 29.515865, states[40]= 0.010293
Saving checkpoint... 
Iteration: 1368391345, states[0] = 25.481770, states[40]= 0.000088
Saving checkpoint... 
Iteration: 1378076917, states[0] = 13.876039, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1387609767, states[0] = -22.482617, states[40]= 0.000261
Saving checkpoint... 
Iteration: 1397279251, states[0] = -27.796504, states[40]= 0.000281
Saving checkpoint... 
Iteration: 1406883182, states[0] = 27.382390, states[40]= 0.000412
Saving checkpoint... 
Iteration: 1416467703, states[0] = -59.579538, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1426137413, states[0] = -65.370653, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1435685150, states[0] = -84.920606, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445133393, states[0] = -62.260352, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1454678755, states[0] = -84.870151, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1464079792, states[0] = 5.225336, states[40]= 0.000113
Saving checkpoint... 
Iteration: 1473512262, states[0] = -84.892036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1482961821, states[0] = -60.652646, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1492504015, states[0] = -84.816632, states[40]= 0.000001
Total time: 3000033.300000
State Variables:
 - v in component membrane (millivolt): -84.838778
 - CaMKt in component CaMK (millimolar): 0.217500
 - cass in component intracellular_ions (millimolar): 0.000172
 - nai in component intracellular_ions (millimolar): 7.290616
 - nass in component intracellular_ions (millimolar): 7.290970
 - ki in component intracellular_ions (millimolar): 143.824987
 - kss in component intracellular_ions (millimolar): 143.824952
 - cansr in component intracellular_ions (millimolar): 3.341519
 - cajsr in component intracellular_ions (millimolar): 1.928558
 - cai in component intracellular_ions (millimolar): 0.000162
 - m in component INa (dimensionless): 0.009965
 - hf in component INa (dimensionless): 0.583926
 - hs in component INa (dimensionless): 0.582872
 - j in component INa (dimensionless): 0.553061
 - hsp in component INa (dimensionless): 0.331369
 - jp in component INa (dimensionless): 0.511172
 - mL in component INaL (dimensionless): 0.000335
 - hL in component INaL (dimensionless): 0.182549
 - hLp in component INaL (dimensionless): 0.074415
 - a in component Ito (dimensionless): 0.001229
 - iF in component Ito (dimensionless): 0.999236
 - iS in component Ito (dimensionless): 0.130926
 - ap in component Ito (dimensionless): 0.000626
 - iFp in component Ito (dimensionless): 0.999237
 - iSp in component Ito (dimensionless): 0.146340
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.677006
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.928607
 - jca in component ICaL (dimensionless): 0.911173
 - ffp in component ICaL (dimensionless): 0.998913
 - fcafp in component ICaL (dimensionless): 0.999939
 - nca in component ICaL (dimensionless): 0.042206
 - xrf in component IKr (dimensionless): 0.101431
 - xrs in component IKr (dimensionless): 0.872990
 - xs1 in component IKs (dimensionless): 0.570939
 - xs2 in component IKs (dimensionless): 0.007266
 - xk1 in component IK1 (dimensionless): 0.996738
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000001
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
02:29:29 (4152): called boinc_finish(0)

</stderr_txt>
]]>


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