𝕏

Task 56060005

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1
Workunit 26622276
Created 4 Jul 2024, 18:46:36 UTC
Sent 4 Jul 2024, 19:10:52 UTC
Report deadline 7 Jul 2024, 22:03:40 UTC
Received 4 Jul 2024, 22:54:30 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 231681
Run time 1 hours 8 min 16 sec
CPU time 1 hours 1 min 14 sec
Validate state Valid
Credit 50.28
Device peak FLOPS 5.60 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-apple-darwin
Peak working set size 1.72 MB
Peak swap size 32.57 GB
Peak disk usage 0.06 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.317322
     * GNaL_b in INaL: 0.005813
     * Gto_b in Ito: 0.085070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009533
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.162949
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.607826
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032101
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 23001709, states[0] = 47.192459, states[40]= 0.315330
Saving checkpoint... 
Iteration: 41686095, states[0] = -27.277325, states[40]= 0.004405
Saving checkpoint... 
Iteration: 60517960, states[0] = 30.611992, states[40]= 0.005258
Saving checkpoint... 
Iteration: 79272807, states[0] = -60.704101, states[40]= 0.000039
Saving checkpoint... 
Iteration: 101188737, states[0] = -26.161523, states[40]= 0.004660
Saving checkpoint... 
Iteration: 124055999, states[0] = 21.643461, states[40]= 0.003937
Saving checkpoint... 
Iteration: 146440095, states[0] = -94.750106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170759241, states[0] = -51.222326, states[40]= 0.000189
Saving checkpoint... 
Iteration: 197075169, states[0] = 15.833638, states[40]= 0.004834
Saving checkpoint... 
Iteration: 223583994, states[0] = 12.935027, states[40]= 0.005051


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.317322
     * GNaL_b in INaL: 0.005813
     * Gto_b in Ito: 0.085070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009533
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.162949
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.607826
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032101
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 223583994
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 12.935027 (After loading)
 - states[40]: 0.005051 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.317322
     * GNaL_b in INaL: 0.005813
     * Gto_b in Ito: 0.085070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009533
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.162949
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.607826
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032101
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 223583994
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 12.935027 (After loading)
 - states[40]: 0.005051 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 249630869, states[0] = -4.378643, states[40]= 0.003976
Saving checkpoint... 
Iteration: 275564795, states[0] = 19.104761, states[40]= 0.004428
Saving checkpoint... 
Iteration: 301464387, states[0] = -94.758790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326920320, states[0] = -94.733005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353129650, states[0] = -3.856539, states[40]= 0.004081
Saving checkpoint... 
Iteration: 379836252, states[0] = -94.635900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406553907, states[0] = 22.352417, states[40]= 0.003846
Saving checkpoint... 
Iteration: 433085301, states[0] = 12.506671, states[40]= 0.005073
Saving checkpoint... 
Iteration: 460150732, states[0] = -13.000734, states[40]= 0.002634
Saving checkpoint... 
Iteration: 487727736, states[0] = -38.097134, states[40]= 0.001342
Saving checkpoint... 
Iteration: 513723410, states[0] = -36.546573, states[40]= 0.001640
Saving checkpoint... 
Iteration: 539358042, states[0] = -94.669304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564522564, states[0] = 30.475058, states[40]= 0.003262
Saving checkpoint... 
Iteration: 589856689, states[0] = -94.667312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615408360, states[0] = -94.723051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641474839, states[0] = -94.762463, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667732932, states[0] = -40.023556, states[40]= 0.001036
Saving checkpoint... 
Iteration: 694305774, states[0] = -90.321109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 721239717, states[0] = -42.651140, states[40]= 0.000716
Saving checkpoint... 
Iteration: 747797777, states[0] = -79.332816, states[40]= 0.000002
Saving checkpoint... 
Iteration: 774625904, states[0] = -2.314179, states[40]= 0.004372
Saving checkpoint... 
Iteration: 801810155, states[0] = -93.200573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828620566, states[0] = -0.190956, states[40]= 0.004699
Saving checkpoint... 
Iteration: 855178969, states[0] = -22.790357, states[40]= 0.005148
Saving checkpoint... 
Iteration: 881427774, states[0] = -94.736796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908315323, states[0] = -94.282768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 934542958, states[0] = 25.521261, states[40]= 0.003238
Saving checkpoint... 
Iteration: 960059523, states[0] = 20.696541, states[40]= 0.004162
Saving checkpoint... 
Iteration: 985102109, states[0] = 6.666020, states[40]= 0.005167
Saving checkpoint... 
Iteration: 1012284145, states[0] = -64.936136, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1039951424, states[0] = -94.750498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065878183, states[0] = -94.693001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093161358, states[0] = -17.207647, states[40]= 0.003556
Saving checkpoint... 
Iteration: 1120626903, states[0] = -2.720423, states[40]= 0.004299
Saving checkpoint... 
Iteration: 1147791208, states[0] = -71.172260, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1175158149, states[0] = -16.012574, states[40]= 0.003109
Saving checkpoint... 
Iteration: 1202077776, states[0] = 15.007736, states[40]= 0.004910
Saving checkpoint... 
Iteration: 1229256976, states[0] = -49.944078, states[40]= 0.000233
Saving checkpoint... 
Iteration: 1256899518, states[0] = -94.713919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1284603336, states[0] = 6.227000, states[40]= 0.005159
Saving checkpoint... 
Iteration: 1311540789, states[0] = 26.138546, states[40]= 0.003134
Saving checkpoint... 
Iteration: 1339014083, states[0] = 30.954112, states[40]= 0.013749


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.317322
     * GNaL_b in INaL: 0.005813
     * Gto_b in Ito: 0.085070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009533
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.162949
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.607826
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032101
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1339014083
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 30.954112 (After loading)
 - states[40]: 0.013749 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1366444751, states[0] = -94.746065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394041253, states[0] = 26.007147, states[40]= 0.003156


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-CLVPET_Block_Kr_70-conf_675_1_r1536184317_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3360000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 103.317322
     * GNaL_b in INaL: 0.005813
     * Gto_b in Ito: 0.085070
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.009533
     * GKs_b in IKs: 0.001940
     * GK1_b in IK1: 0.162949
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.607826
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032101
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1394041253
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: 26.007147 (After loading)
 - states[40]: 0.003156 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1421939554, states[0] = -94.742921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449617898, states[0] = 0.841952, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1476954137, states[0] = -94.750847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1503991858, states[0] = 21.066946, states[40]= 0.005305
Saving checkpoint... 
Iteration: 1529998461, states[0] = -44.343238, states[40]= 0.000816
Saving checkpoint... 
Iteration: 1554203727, states[0] = -94.651863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577556901, states[0] = -94.537407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1600715127, states[0] = -94.488072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624215577, states[0] = -94.416319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1648206662, states[0] = -94.403219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673583127, states[0] = -94.421069, states[40]= 0.000000
Total time: 3360000.000000
State Variables:
 - v in component membrane (millivolt): -94.278692
 - CaMKt in component CaMK (millimolar): 0.001267
 - cass in component intracellular_ions (millimolar): 0.000083
 - nai in component intracellular_ions (millimolar): 6.151874
 - nass in component intracellular_ions (millimolar): 6.151948
 - ki in component intracellular_ions (millimolar): 145.774656
 - kss in component intracellular_ions (millimolar): 145.774649
 - cansr in component intracellular_ions (millimolar): 1.481989
 - cajsr in component intracellular_ions (millimolar): 1.481457
 - cai in component intracellular_ions (millimolar): 0.000085
 - m in component INa (dimensionless): 0.003853
 - hf in component INa (dimensionless): 0.868759
 - hs in component INa (dimensionless): 0.868759
 - j in component INa (dimensionless): 0.868761
 - hsp in component INa (dimensionless): 0.705017
 - jp in component INa (dimensionless): 0.868762
 - mL in component INaL (dimensionless): 0.000056
 - hL in component INaL (dimensionless): 0.712436
 - hLp in component INaL (dimensionless): 0.519405
 - a in component Ito (dimensionless): 0.000650
 - iF in component Ito (dimensionless): 0.999855
 - iS in component Ito (dimensionless): 0.995863
 - ap in component Ito (dimensionless): 0.000331
 - iFp in component Ito (dimensionless): 0.999855
 - iSp in component Ito (dimensionless): 0.998502
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.997524
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002461
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.003579
 - xs1 in component IKs (dimensionless): 0.036672
 - xs2 in component IKs (dimensionless): 0.000094
 - xk1 in component IK1 (dimensionless): 0.997496
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
19:37:43 (91344): called boinc_finish(0)

</stderr_txt>
]]>