𝕏

Task 56058382

Name HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_MID_6000-conf_573_0
Workunit 26621465
Created 4 Jul 2024, 18:45:49 UTC
Sent 4 Jul 2024, 19:07:08 UTC
Report deadline 7 Jul 2024, 19:07:08 UTC
Received 5 Jul 2024, 1:32:56 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 237908
Run time 2 hours 46 min 45 sec
CPU time 1 hours 55 min 11 sec
Validate state Valid
Credit 45.95
Device peak FLOPS 1.88 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 9.63 MB
Peak swap size 5.15 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_MID_6000-conf_573.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_MID_6000-conf_573_0_r463120935_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704204347457747_ORdGradInc_k_27-Drouin_MID_6000-conf_573_0_r463120935_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.941852
     * GNaL_b in INaL: 0.005910
     * Gto_b in Ito: 0.085173
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031774
     * GKs_b in IKs: 0.001924
     * GK1_b in IK1: 0.162961
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.500012
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033847
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 500.000000
     * CL_0 in membrane: 6000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10424767, states[0] = -94.193930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 20850926, states[0] = -94.153607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29991440, states[0] = -94.153736, states[40]= 0.000001
Saving checkpoint... 
Iteration: 40691342, states[0] = -94.178680, states[40]= 0.000001
Saving checkpoint... 
Iteration: 51346620, states[0] = -93.799024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61744426, states[0] = -94.193213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71973629, states[0] = -94.188816, states[40]= 0.000001
Saving checkpoint... 
Iteration: 82017394, states[0] = -94.221899, states[40]= 0.000001
Saving checkpoint... 
Iteration: 90539507, states[0] = -94.175183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 98865453, states[0] = -94.199250, states[40]= 0.000001
Saving checkpoint... 
Iteration: 109349640, states[0] = -94.219808, states[40]= 0.000001
Saving checkpoint... 
Iteration: 118463865, states[0] = -94.218559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 128323538, states[0] = -94.207586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 138347860, states[0] = -93.882232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148713953, states[0] = -94.216897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 158743173, states[0] = -94.208224, states[40]= 0.000001
Saving checkpoint... 
Iteration: 169739208, states[0] = -94.217690, states[40]= 0.000001
Saving checkpoint... 
Iteration: 181339052, states[0] = -94.226916, states[40]= 0.000001
Saving checkpoint... 
Iteration: 192712659, states[0] = -94.234309, states[40]= 0.000001
Saving checkpoint... 
Iteration: 203251092, states[0] = -94.212402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 213533310, states[0] = -94.186182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 223989144, states[0] = -94.215214, states[40]= 0.000001
Saving checkpoint... 
Iteration: 234582430, states[0] = -94.208671, states[40]= 0.000001
Saving checkpoint... 
Iteration: 244839455, states[0] = -94.217274, states[40]= 0.000001
Saving checkpoint... 
Iteration: 255129163, states[0] = 5.904120, states[40]= 0.000091
Saving checkpoint... 
Iteration: 266069890, states[0] = -94.214347, states[40]= 0.000001
Saving checkpoint... 
Iteration: 276699495, states[0] = -94.233408, states[40]= 0.000001
Saving checkpoint... 
Iteration: 284736757, states[0] = -94.209932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293849595, states[0] = -94.209561, states[40]= 0.000001
Saving checkpoint... 
Iteration: 304187026, states[0] = -94.231909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 314533303, states[0] = -94.210629, states[40]= 0.000001
Saving checkpoint... 
Iteration: 324594067, states[0] = -94.212358, states[40]= 0.000001
Saving checkpoint... 
Iteration: 333702647, states[0] = -94.233456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 343021057, states[0] = -94.236696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 353509773, states[0] = -94.210517, states[40]= 0.000001
Saving checkpoint... 
Iteration: 364003835, states[0] = -94.237034, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374604085, states[0] = -94.209929, states[40]= 0.000001
Saving checkpoint... 
Iteration: 384864076, states[0] = -94.239344, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394838172, states[0] = -94.216564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 404066202, states[0] = -94.213618, states[40]= 0.000001
Saving checkpoint... 
Iteration: 414390265, states[0] = -94.010950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424558489, states[0] = -94.221377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 434816218, states[0] = -94.208777, states[40]= 0.000001
Saving checkpoint... 
Iteration: 445426491, states[0] = -94.224291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 455435869, states[0] = -94.210255, states[40]= 0.000001
Saving checkpoint... 
Iteration: 465903261, states[0] = -94.238475, states[40]= 0.000001
Saving checkpoint... 
Iteration: 476134181, states[0] = -94.212441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 486710147, states[0] = -94.233192, states[40]= 0.000001
Saving checkpoint... 
Iteration: 497190349, states[0] = -94.211778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 507422930, states[0] = -94.073881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517775292, states[0] = -94.216707, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528047847, states[0] = 32.691281, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538093334, states[0] = -94.233270, states[40]= 0.000001
Saving checkpoint... 
Iteration: 548151089, states[0] = -94.211792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 558519522, states[0] = -94.176220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569167905, states[0] = -94.211492, states[40]= 0.000001
Saving checkpoint... 
Iteration: 579804714, states[0] = -94.237567, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589802315, states[0] = -94.215792, states[40]= 0.000001
Saving checkpoint... 
Iteration: 600412997, states[0] = -94.056086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610934033, states[0] = -94.213778, states[40]= 0.000001
Saving checkpoint... 
Iteration: 621184868, states[0] = -19.325043, states[40]= 0.002101
Saving checkpoint... 
Iteration: 631445967, states[0] = -94.222551, states[40]= 0.000001
Saving checkpoint... 
Iteration: 641641791, states[0] = -94.207968, states[40]= 0.000001
Saving checkpoint... 
Iteration: 652269909, states[0] = -94.227135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 662868725, states[0] = -94.207094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 672753597, states[0] = -94.235099, states[40]= 0.000001
Saving checkpoint... 
Iteration: 683101005, states[0] = -94.211366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 693633919, states[0] = -94.220438, states[40]= 0.000001
Saving checkpoint... 
Iteration: 703678585, states[0] = -94.217108, states[40]= 0.000001
Saving checkpoint... 
Iteration: 714006733, states[0] = 25.789077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723899146, states[0] = -94.236780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 733459710, states[0] = -94.221526, states[40]= 0.000001
Saving checkpoint... 
Iteration: 743824037, states[0] = -94.206659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 754276678, states[0] = -94.226247, states[40]= 0.000001
Saving checkpoint... 
Iteration: 764279082, states[0] = -94.209228, states[40]= 0.000001
Saving checkpoint... 
Iteration: 774131079, states[0] = 5.203878, states[40]= 0.000105
Saving checkpoint... 
Iteration: 784439327, states[0] = -94.221676, states[40]= 0.000001
Saving checkpoint... 
Iteration: 794466874, states[0] = -94.207774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 804587808, states[0] = -94.207082, states[40]= 0.000001
Saving checkpoint... 
Iteration: 815202753, states[0] = -94.209510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826057158, states[0] = -94.232407, states[40]= 0.000001
Saving checkpoint... 
Iteration: 836505377, states[0] = -94.207279, states[40]= 0.000001
Saving checkpoint... 
Iteration: 847205689, states[0] = -94.227725, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857927579, states[0] = -94.205637, states[40]= 0.000001
Saving checkpoint... 
Iteration: 868649547, states[0] = -94.216531, states[40]= 0.000001
Saving checkpoint... 
Iteration: 879103506, states[0] = 15.139918, states[40]= 0.000010
Saving checkpoint... 
Iteration: 889036093, states[0] = -94.232595, states[40]= 0.000001
Saving checkpoint... 
Iteration: 898989032, states[0] = -94.211138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 909220601, states[0] = -31.231225, states[40]= 0.004786
Saving checkpoint... 
Iteration: 920049807, states[0] = -94.210298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 930596328, states[0] = -94.208998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 940774981, states[0] = -94.213842, states[40]= 0.000001
Saving checkpoint... 
Iteration: 950603445, states[0] = -94.206031, states[40]= 0.000001
Saving checkpoint... 
Iteration: 961002704, states[0] = -94.233033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971351081, states[0] = -94.207297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 981820136, states[0] = -94.235105, states[40]= 0.000001
Saving checkpoint... 
Iteration: 992574618, states[0] = -94.205876, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1002885466, states[0] = -94.235036, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1013227351, states[0] = -94.207955, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1024143348, states[0] = -94.228437, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1034562658, states[0] = -94.205647, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1042312015, states[0] = -94.223285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1051080946, states[0] = -94.230170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1059392116, states[0] = -94.010697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1067464829, states[0] = -94.205932, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1076517403, states[0] = -94.205586, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1084744399, states[0] = -94.213368, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1093455092, states[0] = -94.219195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1102259337, states[0] = -94.224393, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1110731925, states[0] = -94.230775, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1119310662, states[0] = -93.725632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127230096, states[0] = -94.207158, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1136156421, states[0] = -94.207749, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1145001099, states[0] = -94.209324, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1152919062, states[0] = -94.233589, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1161743633, states[0] = -94.231213, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170539027, states[0] = -94.183570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179634050, states[0] = -94.217170, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1188420214, states[0] = -94.064679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197354115, states[0] = -93.905241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205934140, states[0] = -94.203260, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1213739560, states[0] = -94.212574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1221884200, states[0] = -94.233564, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1230351903, states[0] = -93.897573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1238660090, states[0] = -94.203840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1247008634, states[0] = -94.208544, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1255870485, states[0] = -94.210261, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1264046271, states[0] = -94.229760, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1272815692, states[0] = -94.233070, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1281238380, states[0] = -41.679318, states[40]= 0.001597
Saving checkpoint... 
Iteration: 1289398626, states[0] = -94.204823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1298431480, states[0] = -94.204559, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1307889598, states[0] = -94.202664, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1317498360, states[0] = -94.155906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328002449, states[0] = -94.208066, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338148038, states[0] = -1.251553, states[40]= 0.000315
Saving checkpoint... 
Iteration: 1348349956, states[0] = -94.220163, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1358779680, states[0] = -94.202610, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369558771, states[0] = -94.214964, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1380150833, states[0] = -2.434394, states[40]= 0.000362
Saving checkpoint... 
Iteration: 1390933896, states[0] = -94.208485, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400163934, states[0] = -94.205887, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1409120826, states[0] = -94.206238, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1420099956, states[0] = -94.227090, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1430762909, states[0] = -94.202173, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1441282595, states[0] = -94.221418, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1452083966, states[0] = 22.150325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1463069413, states[0] = -94.206400, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1472985619, states[0] = -94.201348, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1483730468, states[0] = -94.210897, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1494457659, states[0] = -94.115399, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.077120
 - CaMKt in component CaMK (millimolar): 0.001353
 - cass in component intracellular_ions (millimolar): 0.000095
 - nai in component intracellular_ions (millimolar): 7.718494
 - nass in component intracellular_ions (millimolar): 7.718642
 - ki in component intracellular_ions (millimolar): 144.119862
 - kss in component intracellular_ions (millimolar): 144.119848
 - cansr in component intracellular_ions (millimolar): 1.761974
 - cajsr in component intracellular_ions (millimolar): 1.763199
 - cai in component intracellular_ions (millimolar): 0.000100
 - m in component INa (dimensionless): 0.003933
 - hf in component INa (dimensionless): 0.864936
 - hs in component INa (dimensionless): 0.864936
 - j in component INa (dimensionless): 0.864937
 - hsp in component INa (dimensionless): 0.698081
 - jp in component INa (dimensionless): 0.864937
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.706876
 - hLp in component INaL (dimensionless): 0.513059
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999849
 - iS in component Ito (dimensionless): 0.999131
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999849
 - iSp in component Ito (dimensionless): 0.999679
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.999267
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004209
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.000652
 - xs1 in component IKs (dimensionless): 0.019833
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997545
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
01:32:38 (9148): called boinc_finish(0)

</stderr_txt>
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