𝕏

Task 56038292

Name HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384_1
Workunit 26611443
Created 4 Jul 2024, 18:34:35 UTC
Sent 4 Jul 2024, 18:34:41 UTC
Report deadline 7 Jul 2024, 18:34:41 UTC
Received 6 Jul 2024, 9:04:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238328
Run time 2 hours 46 min 15 sec
CPU time 1 hours 28 min 45 sec
Validate state Valid
Credit 49.23
Device peak FLOPS 4.44 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.67 MB
Peak swap size 5.31 MB
Peak disk usage 0.03 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384_1_r93126853_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384_1_r93126853_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.937978
     * GNaL_b in INaL: 0.005886
     * Gto_b in Ito: 0.084096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031886
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163558
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.258056
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032041
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 10918449, states[0] = -94.212229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 18611531, states[0] = -94.188259, states[40]= 0.000001
Saving checkpoint... 
Iteration: 26201358, states[0] = -94.189415, states[40]= 0.000001
Saving checkpoint... 
Iteration: 33813054, states[0] = -94.191702, states[40]= 0.000001
Saving checkpoint... 
Iteration: 41452613, states[0] = -94.193823, states[40]= 0.000001
Saving checkpoint... 
Iteration: 49136894, states[0] = -94.195402, states[40]= 0.000001
Saving checkpoint... 
Iteration: 56795383, states[0] = -94.197867, states[40]= 0.000001
Saving checkpoint... 
Iteration: 64465925, states[0] = -94.200195, states[40]= 0.000001
Saving checkpoint... 
Iteration: 72206412, states[0] = -94.201840, states[40]= 0.000001
Saving checkpoint... 
Iteration: 79816221, states[0] = -94.204575, states[40]= 0.000001
Saving checkpoint... 
Iteration: 87471460, states[0] = -94.206672, states[40]= 0.000001
Saving checkpoint... 
Iteration: 95079656, states[0] = 23.698979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 102674801, states[0] = -14.984976, states[40]= 0.000903
Saving checkpoint... 
Iteration: 110316695, states[0] = -93.762331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 117848670, states[0] = -93.898606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125220833, states[0] = -32.520492, states[40]= 0.004576
Saving checkpoint... 
Iteration: 133121250, states[0] = -94.228306, states[40]= 0.000001
Saving checkpoint... 
Iteration: 140930753, states[0] = -94.247123, states[40]= 0.000001
Saving checkpoint... 
Iteration: 148547421, states[0] = -94.244654, states[40]= 0.000001
Saving checkpoint... 
Iteration: 156200693, states[0] = -94.240297, states[40]= 0.000001
Saving checkpoint... 
Iteration: 163848829, states[0] = -94.236286, states[40]= 0.000001
Saving checkpoint... 
Iteration: 171511531, states[0] = -94.232453, states[40]= 0.000001
Saving checkpoint... 
Iteration: 179163105, states[0] = -94.229510, states[40]= 0.000001
Saving checkpoint... 
Iteration: 186762100, states[0] = -94.227943, states[40]= 0.000001
Saving checkpoint... 
Iteration: 194400030, states[0] = -94.225998, states[40]= 0.000001
Saving checkpoint... 
Iteration: 202060102, states[0] = -94.224143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 209660882, states[0] = -94.223211, states[40]= 0.000001
Saving checkpoint... 
Iteration: 217307270, states[0] = -94.222052, states[40]= 0.000001
Saving checkpoint... 
Iteration: 224942277, states[0] = -94.221204, states[40]= 0.000001
Saving checkpoint... 
Iteration: 232603966, states[0] = 14.582700, states[40]= 0.000014
Saving checkpoint... 
Iteration: 240128105, states[0] = 5.721979, states[40]= 0.000106
Saving checkpoint... 
Iteration: 247807330, states[0] = -93.734826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255483825, states[0] = -94.164298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263143345, states[0] = -94.237014, states[40]= 0.000001
Saving checkpoint... 
Iteration: 270767567, states[0] = -94.249592, states[40]= 0.000001
Saving checkpoint... 
Iteration: 278362863, states[0] = -94.250873, states[40]= 0.000001
Saving checkpoint... 
Iteration: 285981480, states[0] = -94.248683, states[40]= 0.000001
Saving checkpoint... 
Iteration: 293693976, states[0] = -94.242047, states[40]= 0.000001
Saving checkpoint... 
Iteration: 301343391, states[0] = -94.237501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309378220, states[0] = -94.226325, states[40]= 0.000001
Saving checkpoint... 
Iteration: 318839723, states[0] = -94.237476, states[40]= 0.000001
Saving checkpoint... 
Iteration: 328254064, states[0] = -94.248611, states[40]= 0.000001
Saving checkpoint... 
Iteration: 336538157, states[0] = -94.232298, states[40]= 0.000001
Saving checkpoint... 
Iteration: 344189371, states[0] = -94.229138, states[40]= 0.000001
Saving checkpoint... 
Iteration: 351797942, states[0] = -94.227203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 359441327, states[0] = -94.225063, states[40]= 0.000001
Saving checkpoint... 
Iteration: 367092138, states[0] = -94.223233, states[40]= 0.000001
Saving checkpoint... 
Iteration: 374683882, states[0] = -94.222277, states[40]= 0.000001
Saving checkpoint... 
Iteration: 382350846, states[0] = -94.220892, states[40]= 0.000001
Saving checkpoint... 
Iteration: 390010578, states[0] = 29.502754, states[40]= -0.000000
Saving checkpoint... 
Iteration: 397653165, states[0] = -4.466738, states[40]= 0.000474
Saving checkpoint... 
Iteration: 405255981, states[0] = -58.496688, states[40]= 0.000153
Saving checkpoint... 
Iteration: 414064802, states[0] = -94.231051, states[40]= 0.000001
Saving checkpoint... 
Iteration: 421770303, states[0] = -94.227056, states[40]= 0.000001
Saving checkpoint... 
Iteration: 429396997, states[0] = -94.225060, states[40]= 0.000001
Saving checkpoint... 
Iteration: 437008735, states[0] = -94.223558, states[40]= 0.000001
Saving checkpoint... 
Iteration: 444651116, states[0] = -94.221976, states[40]= 0.000001
Saving checkpoint... 
Iteration: 452237138, states[0] = -94.221144, states[40]= 0.000001
Saving checkpoint... 
Iteration: 459923209, states[0] = -94.219753, states[40]= 0.000001
Saving checkpoint... 
Iteration: 467563160, states[0] = 28.752962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475254792, states[0] = -57.522347, states[40]= 0.000178
Saving checkpoint... 
Iteration: 482909398, states[0] = -94.065481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 490531394, states[0] = -94.196448, states[40]= 0.000001
Saving checkpoint... 
Iteration: 498119387, states[0] = -94.229996, states[40]= 0.000001
Saving checkpoint... 
Iteration: 505764355, states[0] = -94.247554, states[40]= 0.000001
Saving checkpoint... 
Iteration: 513423912, states[0] = -94.248139, states[40]= 0.000001
Saving checkpoint... 
Iteration: 521076157, states[0] = -94.243909, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528677601, states[0] = -94.240591, states[40]= 0.000001
Saving checkpoint... 
Iteration: 536320033, states[0] = -94.236175, states[40]= 0.000001
Saving checkpoint... 
Iteration: 543944669, states[0] = -94.232738, states[40]= 0.000001
Saving checkpoint... 
Iteration: 551533100, states[0] = -94.230555, states[40]= 0.000001
Saving checkpoint... 
Iteration: 559156619, states[0] = -94.227896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 566825737, states[0] = -94.224900, states[40]= 0.000001
Saving checkpoint... 
Iteration: 574484544, states[0] = -94.222645, states[40]= 0.000001
Saving checkpoint... 
Iteration: 582126870, states[0] = -94.221007, states[40]= 0.000001
Saving checkpoint... 
Iteration: 589775245, states[0] = -94.219633, states[40]= 0.000001
Saving checkpoint... 
Iteration: 597458730, states[0] = -94.218340, states[40]= 0.000001
Saving checkpoint... 
Iteration: 605119062, states[0] = 9.031132, states[40]= 0.000052
Saving checkpoint... 
Iteration: 612693921, states[0] = -23.126395, states[40]= 0.004890
Saving checkpoint... 
Iteration: 620325099, states[0] = -93.816565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627927467, states[0] = -94.094686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635516721, states[0] = -94.186287, states[40]= 0.000001
Saving checkpoint... 
Iteration: 643149549, states[0] = -94.235013, states[40]= 0.000001
Saving checkpoint... 
Iteration: 650800464, states[0] = -94.247366, states[40]= 0.000001
Saving checkpoint... 
Iteration: 658433695, states[0] = -94.246673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 666048776, states[0] = -94.243496, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673688994, states[0] = -94.238958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 681377162, states[0] = -94.233303, states[40]= 0.000001
Saving checkpoint... 
Iteration: 688960607, states[0] = -94.231069, states[40]= 0.000001
Saving checkpoint... 
Iteration: 696595641, states[0] = -94.227919, states[40]= 0.000001
Saving checkpoint... 
Iteration: 704282236, states[0] = -94.224384, states[40]= 0.000001
Saving checkpoint... 
Iteration: 712007871, states[0] = -94.221157, states[40]= 0.000001
Saving checkpoint... 
Iteration: 719655061, states[0] = -94.219527, states[40]= 0.000001
Saving checkpoint... 
Iteration: 727287584, states[0] = -94.218330, states[40]= 0.000001
Saving checkpoint... 
Iteration: 734991652, states[0] = -94.216953, states[40]= 0.000001
Saving checkpoint... 
Iteration: 742652051, states[0] = -3.935668, states[40]= 0.000455
Saving checkpoint... 
Iteration: 750342947, states[0] = -93.887011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 757965573, states[0] = -94.142420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765546867, states[0] = -94.202161, states[40]= 0.000001
Saving checkpoint... 
Iteration: 773178358, states[0] = -94.238285, states[40]= 0.000001
Saving checkpoint... 
Iteration: 780818101, states[0] = -94.246495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 788434887, states[0] = -94.245509, states[40]= 0.000001
Saving checkpoint... 
Iteration: 796033318, states[0] = -94.242829, states[40]= 0.000001
Saving checkpoint... 
Iteration: 803687923, states[0] = -94.237852, states[40]= 0.000001
Saving checkpoint... 
Iteration: 811352029, states[0] = -94.232856, states[40]= 0.000001
Saving checkpoint... 
Iteration: 818993250, states[0] = -94.229135, states[40]= 0.000001
Saving checkpoint... 
Iteration: 826622035, states[0] = -94.226234, states[40]= 0.000001
Saving checkpoint... 
Iteration: 834296675, states[0] = -94.223009, states[40]= 0.000001
Saving checkpoint... 
Iteration: 841965596, states[0] = -94.220533, states[40]= 0.000001
Saving checkpoint... 
Iteration: 849593945, states[0] = -94.218992, states[40]= 0.000001
Saving checkpoint... 
Iteration: 857217966, states[0] = -94.217752, states[40]= 0.000001
Saving checkpoint... 
Iteration: 864844727, states[0] = -94.216706, states[40]= 0.000001
Saving checkpoint... 
Iteration: 872520736, states[0] = 33.172760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880134091, states[0] = 3.478748, states[40]= 0.000164
Saving checkpoint... 
Iteration: 887774055, states[0] = -79.163423, states[40]= 0.000007
Saving checkpoint... 
Iteration: 895411241, states[0] = -94.065189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903045560, states[0] = -94.200310, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910714216, states[0] = -94.240906, states[40]= 0.000001
Saving checkpoint... 
Iteration: 918369516, states[0] = -94.245349, states[40]= 0.000001
Saving checkpoint... 
Iteration: 926007537, states[0] = -94.242452, states[40]= 0.000001
Saving checkpoint... 
Iteration: 933614139, states[0] = -94.239080, states[40]= 0.000001
Saving checkpoint... 
Iteration: 941215057, states[0] = -94.235790, states[40]= 0.000001
Saving checkpoint... 
Iteration: 948828609, states[0] = -94.232312, states[40]= 0.000001
Saving checkpoint... 
Iteration: 956537074, states[0] = -94.226912, states[40]= 0.000001
Saving checkpoint... 
Iteration: 964446821, states[0] = -94.219698, states[40]= 0.000001
Saving checkpoint... 
Iteration: 971935939, states[0] = -94.219774, states[40]= 0.000001
Saving checkpoint... 
Iteration: 980993685, states[0] = -94.242362, states[40]= 0.000001
Saving checkpoint... 
Iteration: 989304270, states[0] = -94.221528, states[40]= 0.000001
Saving checkpoint... 
Iteration: 997373054, states[0] = -94.215351, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1005008335, states[0] = 27.808823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012580166, states[0] = 23.184583, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1020831624, states[0] = -94.244501, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1028227882, states[0] = -94.240946, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1035654480, states[0] = -94.232425, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1043296411, states[0] = -94.243843, states[40]= 0.000001


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384_1_r93126853_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704202618136010_ORdGradInc_k_27-Drouin_MID_5000-conf_384_1_r93126853_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 102.937978
     * GNaL_b in INaL: 0.005886
     * Gto_b in Ito: 0.084096
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031886
     * GKs_b in IKs: 0.001918
     * GK1_b in IK1: 0.163558
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.258056
     * GKb_b in IKb: 0.003810
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032041
     * celltype in environment: 2.000000
     * nCL_0 in membrane: 600.000000
     * CL_0 in membrane: 5000.000000
     * cao in extracellular: 2.700000
     * ko in extracellular: 4.000000
     * nao in extracellular: 150.800000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1043296411
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.243843 (After loading)
 - states[40]: 0.000001 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1073090249, states[0] = -94.216786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1098971515, states[0] = -94.227203, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1124780451, states[0] = -94.214893, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1153716749, states[0] = -94.233874, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1179543368, states[0] = -94.216643, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1200513408, states[0] = -94.179127, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1228603995, states[0] = -94.236821, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1256564463, states[0] = -94.223673, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1282382734, states[0] = -94.212787, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1311322995, states[0] = -94.229295, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1338765236, states[0] = -94.230759, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1364191069, states[0] = -94.220180, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1387391911, states[0] = -94.211805, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1417224582, states[0] = -94.212780, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1445062183, states[0] = 29.043883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473226474, states[0] = -94.236945, states[40]= 0.000001
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.086166
 - CaMKt in component CaMK (millimolar): 0.001790
 - cass in component intracellular_ions (millimolar): 0.000096
 - nai in component intracellular_ions (millimolar): 7.778615
 - nass in component intracellular_ions (millimolar): 7.778767
 - ki in component intracellular_ions (millimolar): 144.037371
 - kss in component intracellular_ions (millimolar): 144.037357
 - cansr in component intracellular_ions (millimolar): 1.796660
 - cajsr in component intracellular_ions (millimolar): 1.798127
 - cai in component intracellular_ions (millimolar): 0.000101
 - m in component INa (dimensionless): 0.003929
 - hf in component INa (dimensionless): 0.865110
 - hs in component INa (dimensionless): 0.865110
 - j in component INa (dimensionless): 0.865111
 - hsp in component INa (dimensionless): 0.698396
 - jp in component INa (dimensionless): 0.865112
 - mL in component INaL (dimensionless): 0.000058
 - hL in component INaL (dimensionless): 0.707137
 - hLp in component INaL (dimensionless): 0.513257
 - a in component Ito (dimensionless): 0.000659
 - iF in component Ito (dimensionless): 0.999850
 - iS in component Ito (dimensionless): 0.997198
 - ap in component Ito (dimensionless): 0.000336
 - iFp in component Ito (dimensionless): 0.999850
 - iSp in component Ito (dimensionless): 0.999031
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.998037
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.004387
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.002441
 - xs1 in component IKs (dimensionless): 0.032574
 - xs2 in component IKs (dimensionless): 0.000096
 - xk1 in component IK1 (dimensionless): 0.997543
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000001
09:08:15 (13396): called boinc_finish(0)

</stderr_txt>
]]>


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