Task 56021329

Name	HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965_2
Workunit	26531252
Created	4 Jul 2024, 16:33:20 UTC
Sent	4 Jul 2024, 16:33:23 UTC
Report deadline	7 Jul 2024, 16:33:23 UTC
Received	5 Jul 2024, 19:32:47 UTC
Server state	Over
Outcome	Success
Client state	Done
Exit status	0 (0x00000000)
Computer ID	222620
Run time	1 hours 17 min 15 sec
CPU time	1 hours 13 min 10 sec
Validate state	Invalid
Credit	0.00
Device peak FLOPS	4.41 GFLOPS
Application version	Human ventricular cell models optimization v0.02 arm64-apple-darwin
Peak working set size	5.27 MB
Peak swap size	32.99 GB
Peak disk usage	0.33 MB
Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965_2_r1018183283_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965_2_r1018183283_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 100.317377
     * GNaL_b in INaL: 0.005523
     * Gto_b in Ito: 0.082192
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032155
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.167987
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.987779
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037137
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 13705822, states[0] = -73.687580, states[40]= 0.000002
Saving checkpoint... 
Iteration: 33103826, states[0] = 6.508491, states[40]= 0.000023
Saving checkpoint... 
Iteration: 52306933, states[0] = -86.759383, states[40]= 0.000001
Saving checkpoint... 
Iteration: 71242454, states[0] = -86.505916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 90590247, states[0] = 10.791933, states[40]= 0.000013
Saving checkpoint... 
Iteration: 108908007, states[0] = -86.962647, states[40]= 0.000002
Saving checkpoint... 
Iteration: 123385814, states[0] = -86.943574, states[40]= 0.000002
Saving checkpoint... 
Iteration: 142563598, states[0] = 22.053973, states[40]= 0.000001
Saving checkpoint... 
Iteration: 162773811, states[0] = -86.690257, states[40]= 0.000001
Saving checkpoint... 
Iteration: 182190907, states[0] = -80.172326, states[40]= 0.000001
Saving checkpoint... 
Iteration: 200758263, states[0] = -86.618143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 219953352, states[0] = -86.996831, states[40]= 0.000002
Saving checkpoint... 
Iteration: 239382970, states[0] = -86.940247, states[40]= 0.000002
Saving checkpoint... 
Iteration: 258186432, states[0] = -73.239369, states[40]= 0.000004
Saving checkpoint... 
Iteration: 277220077, states[0] = -86.369806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 297259093, states[0] = -86.617433, states[40]= 0.000001
Saving checkpoint... 
Iteration: 317137022, states[0] = -21.402782, states[40]= 0.000236
Saving checkpoint... 
Iteration: 336223190, states[0] = -86.390741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355171475, states[0] = -53.076408, states[40]= 0.000059
Saving checkpoint... 
Iteration: 374250807, states[0] = -86.569441, states[40]= 0.000001
Saving checkpoint... 
Iteration: 394155793, states[0] = -37.211632, states[40]= 0.000307
Saving checkpoint... 
Iteration: 412775279, states[0] = -86.684174, states[40]= 0.000001
Saving checkpoint... 
Iteration: 431855714, states[0] = -86.893086, states[40]= 0.000002
Saving checkpoint... 
Iteration: 451136902, states[0] = -21.294804, states[40]= 0.000233
Saving checkpoint... 
Iteration: 470587563, states[0] = 11.638851, states[40]= 0.000011
Saving checkpoint... 
Iteration: 489746621, states[0] = -86.539033, states[40]= 0.000001
Saving checkpoint... 
Iteration: 508809473, states[0] = -86.792979, states[40]= 0.000001
Saving checkpoint... 
Iteration: 528372415, states[0] = -86.911391, states[40]= 0.000002
Saving checkpoint... 
Iteration: 547366032, states[0] = -86.901780, states[40]= 0.000002
Saving checkpoint... 
Iteration: 566537411, states[0] = 30.171504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585714825, states[0] = -86.307798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604918197, states[0] = -86.953235, states[40]= 0.000002
Saving checkpoint... 
Iteration: 624033626, states[0] = 30.886286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642060407, states[0] = 23.218126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 659757115, states[0] = -86.586663, states[40]= 0.000001
Saving checkpoint... 
Iteration: 673869903, states[0] = -86.899927, states[40]= 0.000002
Saving checkpoint... 
Iteration: 693837095, states[0] = -86.845913, states[40]= 0.000002
Saving checkpoint... 
Iteration: 713163993, states[0] = -45.114589, states[40]= 0.000148
Saving checkpoint... 
Iteration: 732145302, states[0] = -28.055091, states[40]= 0.000407
Saving checkpoint... 
Iteration: 750866825, states[0] = -86.891454, states[40]= 0.000002
Saving checkpoint... 
Iteration: 770340299, states[0] = -86.847685, states[40]= 0.000002
Saving checkpoint... 
Iteration: 789826642, states[0] = -86.818896, states[40]= 0.000002
Saving checkpoint... 
Iteration: 809451782, states[0] = -86.963424, states[40]= 0.000002
Saving checkpoint... 
Iteration: 829620608, states[0] = -7.477130, states[40]= 0.000146
Saving checkpoint... 
Iteration: 843513471, states[0] = 29.896708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 864140390, states[0] = -24.075379, states[40]= 0.000314
Saving checkpoint... 
Iteration: 883960141, states[0] = -86.963474, states[40]= 0.000002
Saving checkpoint... 
Iteration: 903767701, states[0] = -86.623632, states[40]= 0.000001
Saving checkpoint... 
Iteration: 923733214, states[0] = -86.429266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943568902, states[0] = 19.898267, states[40]= 0.000001
Saving checkpoint... 
Iteration: 963617507, states[0] = -5.100684, states[40]= 0.000134
Saving checkpoint... 
Iteration: 976683875, states[0] = -68.918994, states[40]= 0.000007
Saving checkpoint... 
Iteration: 997205627, states[0] = -86.153418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1016846202, states[0] = -86.844507, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1036591278, states[0] = 9.879512, states[40]= 0.000016
Saving checkpoint... 
Iteration: 1057259976, states[0] = -86.578346, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1077694471, states[0] = -83.791742, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1097275600, states[0] = -86.646495, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1117812212, states[0] = -86.765806, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1137696640, states[0] = -84.942107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157873004, states[0] = -86.876847, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1177613587, states[0] = -2.357129, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1197193240, states[0] = -82.767783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1216551818, states[0] = 26.246556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236510958, states[0] = 28.518852, states[40]= -0.000000
Saving checkpoint... 
Iteration: 1255671638, states[0] = -53.130264, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1275024862, states[0] = 31.786776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294658117, states[0] = -39.288134, states[40]= 0.000257
Saving checkpoint... 
Iteration: 1314451431, states[0] = -86.935035, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1334493269, states[0] = -86.951675, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1354323187, states[0] = -86.779359, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1374129300, states[0] = -14.773982, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1393551253, states[0] = 26.434349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1411549890, states[0] = 26.869520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1433233855, states[0] = -86.404228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1453494329, states[0] = -86.945421, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1473355109, states[0] = -86.833654, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1493713674, states[0] = -86.244134, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.820486
 - CaMKt in component CaMK (millimolar): 0.024928
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 8.072427
 - nass in component intracellular_ions (millimolar): 8.072579
 - ki in component intracellular_ions (millimolar): 143.319740
 - kss in component intracellular_ions (millimolar): 143.319702
 - cansr in component intracellular_ions (millimolar): 2.039781
 - cajsr in component intracellular_ions (millimolar): 1.974213
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008168
 - hf in component INa (dimensionless): 0.660287
 - hs in component INa (dimensionless): 0.660258
 - j in component INa (dimensionless): 0.660089
 - hsp in component INa (dimensionless): 0.412272
 - jp in component INa (dimensionless): 0.659969
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.456880
 - hLp in component INaL (dimensionless): 0.223213
 - a in component Ito (dimensionless): 0.001075
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.535486
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999464
 - iSp in component Ito (dimensionless): 0.579327
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877740
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999621
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003797
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507189
 - xs1 in component IKs (dimensionless): 0.332724
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997026
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
14:24:07 (78920): called boinc_finish(0)


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965_2_r1018183283_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703071643700359_ORdGradInc_k_26-BASE_MID-conf_965_2_r1018183283_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 14
     * GNa in INa: 100.317377
     * GNaL_b in INaL: 0.005523
     * Gto_b in Ito: 0.082192
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032155
     * GKs_b in IKs: 0.001925
     * GK1_b in IK1: 0.167987
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.987779
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037137
     * celltype in environment: 2.000000
Starting output configuration...
Output starts at iteration 1499500000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1493713674
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -86.244134 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -86.820486
 - CaMKt in component CaMK (millimolar): 0.024928
 - cass in component intracellular_ions (millimolar): 0.000092
 - nai in component intracellular_ions (millimolar): 8.072427
 - nass in component intracellular_ions (millimolar): 8.072579
 - ki in component intracellular_ions (millimolar): 143.319740
 - kss in component intracellular_ions (millimolar): 143.319702
 - cansr in component intracellular_ions (millimolar): 2.039781
 - cajsr in component intracellular_ions (millimolar): 1.974213
 - cai in component intracellular_ions (millimolar): 0.000096
 - m in component INa (dimensionless): 0.008168
 - hf in component INa (dimensionless): 0.660287
 - hs in component INa (dimensionless): 0.660258
 - j in component INa (dimensionless): 0.660089
 - hsp in component INa (dimensionless): 0.412272
 - jp in component INa (dimensionless): 0.659969
 - mL in component INaL (dimensionless): 0.000230
 - hL in component INaL (dimensionless): 0.456880
 - hLp in component INaL (dimensionless): 0.223213
 - a in component Ito (dimensionless): 0.001075
 - iF in component Ito (dimensionless): 0.999464
 - iS in component Ito (dimensionless): 0.535486
 - ap in component Ito (dimensionless): 0.000548
 - iFp in component Ito (dimensionless): 0.999464
 - iSp in component Ito (dimensionless): 0.579327
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.877740
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999621
 - jca in component ICaL (dimensionless): 0.999941
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.003797
 - xrf in component IKr (dimensionless): 0.000010
 - xrs in component IKr (dimensionless): 0.507189
 - xs1 in component IKs (dimensionless): 0.332724
 - xs2 in component IKs (dimensionless): 0.000217
 - xk1 in component IK1 (dimensionless): 0.997026
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000002
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000002
14:31:52 (80879): called boinc_finish(0)

</stderr_txt>
]]>