𝕏

Task 56020608

Name HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_594_2
Workunit 26345383
Created 4 Jul 2024, 14:37:44 UTC
Sent 4 Jul 2024, 14:37:46 UTC
Report deadline 7 Jul 2024, 14:37:46 UTC
Received 4 Jul 2024, 23:08:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236767
Run time 1 hours 37 min 6 sec
CPU time 1 hours 37 min 6 sec
Validate state Valid
Credit 41.46
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.23 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_594.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_594_2_r487941408_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_594_2_r487941408_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 103.338723
     * GNaL_b in INaL: 0.005827
     * Gto_b in Ito: 0.086327
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031722
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.164898
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.570236
     * GKb_b in IKb: 0.003797
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029643
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 11034291, states[0] = 23.083299, states[40]= 0.002652
Saving checkpoint... 
Iteration: 19527931, states[0] = -94.711496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28063662, states[0] = 14.258414, states[40]= 0.003479
Saving checkpoint... 
Iteration: 34456482, states[0] = -94.649429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 43020859, states[0] = 26.413862, states[40]= 0.002411
Saving checkpoint... 
Iteration: 51539907, states[0] = -94.653855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60002354, states[0] = 40.911133, states[40]= 0.467522
Saving checkpoint... 
Iteration: 68494807, states[0] = -94.633541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76917725, states[0] = -94.654705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85446183, states[0] = -94.610028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93941123, states[0] = -94.649892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102323828, states[0] = -94.500058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 110776987, states[0] = -94.649947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 116858992, states[0] = -94.648380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125256057, states[0] = -94.352302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 133744235, states[0] = -94.647771, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142261444, states[0] = -94.366631, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148131010, states[0] = -28.555476, states[40]= 0.001274
Saving checkpoint... 
Iteration: 157740619, states[0] = -94.646560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 168627981, states[0] = -94.642025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 177168806, states[0] = -63.051806, states[40]= 0.000011
Saving checkpoint... 
Iteration: 185535212, states[0] = -94.629603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193944715, states[0] = -94.643065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202305426, states[0] = -94.464503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 210904029, states[0] = -94.643824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219393981, states[0] = -94.570091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227880559, states[0] = -94.644179, states[40]= 0.000000
Saving checkpoint... 
Iteration: 236348155, states[0] = -94.526589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244813932, states[0] = -94.645130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253339631, states[0] = -94.516078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 261744659, states[0] = -94.645213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267694919, states[0] = -94.644314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276612535, states[0] = -94.639656, states[40]= 0.000000
Saving checkpoint... 
Iteration: 285283429, states[0] = -94.419738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293955897, states[0] = -94.642143, states[40]= 0.000000
Saving checkpoint... 
Iteration: 302544343, states[0] = -94.630557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 311141659, states[0] = -37.525128, states[40]= 0.000562
Saving checkpoint... 
Iteration: 319639835, states[0] = -94.641644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 328116386, states[0] = -16.027336, states[40]= 0.001558
Saving checkpoint... 
Iteration: 336736904, states[0] = -94.644930, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345324872, states[0] = -94.495549, states[40]= 0.000000
Saving checkpoint... 
Iteration: 353797886, states[0] = -94.644946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362236455, states[0] = -94.285525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370732143, states[0] = -94.644804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379266673, states[0] = -94.378505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 387791227, states[0] = -94.644920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396153152, states[0] = -47.848831, states[40]= 0.000137
Saving checkpoint... 
Iteration: 402807268, states[0] = -94.644770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408929437, states[0] = -94.642547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417556965, states[0] = -94.632485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426300397, states[0] = -94.454419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 434946303, states[0] = -94.642081, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443615567, states[0] = -94.639550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452220277, states[0] = -94.225145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460746397, states[0] = -94.644763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469307614, states[0] = -94.467483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477807873, states[0] = -94.644617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486296630, states[0] = -94.447044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494809022, states[0] = -94.644573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 500642122, states[0] = -94.641424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509168539, states[0] = -62.710045, states[40]= 0.000012
Saving checkpoint... 
Iteration: 517696460, states[0] = -94.643808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526090866, states[0] = 2.844400, states[40]= 0.004501
Saving checkpoint... 
Iteration: 534608729, states[0] = -94.638754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 540423358, states[0] = -94.588580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 548910787, states[0] = -94.642713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555096761, states[0] = -0.632318, states[40]= 0.004282
Saving checkpoint... 
Iteration: 563605309, states[0] = -94.638370, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572095517, states[0] = 0.140272, states[40]= 0.004356
Saving checkpoint... 
Iteration: 580529421, states[0] = -94.627050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 589102149, states[0] = -4.271959, states[40]= 0.003738
Saving checkpoint... 
Iteration: 597485245, states[0] = -94.615389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605906782, states[0] = -94.642694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614437048, states[0] = -94.595791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622909763, states[0] = -94.642593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631398590, states[0] = -94.572452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637268177, states[0] = -94.381965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645780701, states[0] = -94.644465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654261487, states[0] = -94.363811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662786748, states[0] = -94.644408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671311796, states[0] = -94.474280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677478679, states[0] = -94.613056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685927259, states[0] = -94.642062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694341118, states[0] = -94.517004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702745010, states[0] = -94.644285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711155746, states[0] = -50.269650, states[40]= 0.000095
Saving checkpoint... 
Iteration: 721094597, states[0] = 0.697421, states[40]= 0.004401
Saving checkpoint... 
Iteration: 729570677, states[0] = -94.633954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 738100062, states[0] = -2.801658, states[40]= 0.003994
Saving checkpoint... 
Iteration: 746687700, states[0] = -94.643098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 755098616, states[0] = -1.828795, states[40]= 0.004137
Saving checkpoint... 
Iteration: 763504833, states[0] = -94.620825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772139455, states[0] = -35.621096, states[40]= 0.000702
Saving checkpoint... 
Iteration: 780590567, states[0] = -94.636389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789329583, states[0] = -94.501469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 798015788, states[0] = 26.863904, states[40]= 0.007815
Saving checkpoint... 
Iteration: 806743565, states[0] = -94.644072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815489283, states[0] = -94.616242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 822171523, states[0] = -65.906113, states[40]= 0.000007
Saving checkpoint... 
Iteration: 830493155, states[0] = -94.617391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 836435638, states[0] = -94.594646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 844920367, states[0] = -94.641918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853411354, states[0] = -94.580704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862305391, states[0] = -94.462768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871026933, states[0] = 25.811728, states[40]= 0.001566
Saving checkpoint... 
Iteration: 879727206, states[0] = -94.643750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887720279, states[0] = -94.643627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896197193, states[0] = -93.640205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904696410, states[0] = -94.643058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913174584, states[0] = -69.453275, states[40]= 0.000004
Saving checkpoint... 
Iteration: 921583749, states[0] = -94.635306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 930109140, states[0] = -9.759870, states[40]= 0.002572
Saving checkpoint... 
Iteration: 939125306, states[0] = -23.683412, states[40]= 0.001390
Saving checkpoint... 
Iteration: 945237193, states[0] = -94.286949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953837265, states[0] = -94.643342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 962304054, states[0] = -94.460155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970798604, states[0] = -94.643741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979295427, states[0] = -94.443705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987728891, states[0] = -94.643565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996214534, states[0] = -94.199478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004977965, states[0] = -94.640162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013691108, states[0] = -94.642691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022395114, states[0] = -94.569142, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031111228, states[0] = -11.533678, states[40]= 0.002213
Saving checkpoint... 
Iteration: 1039600419, states[0] = -94.636959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048120590, states[0] = -19.676461, states[40]= 0.001364
Saving checkpoint... 
Iteration: 1056581125, states[0] = -94.634717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062414451, states[0] = -94.582254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070953872, states[0] = -94.640659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079398451, states[0] = -94.571482, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1087872779, states[0] = -94.642476, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096404243, states[0] = -94.575525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104985653, states[0] = -94.639765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113520517, states[0] = -94.624049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119411942, states[0] = -94.580564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127872463, states[0] = -94.642405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1136355808, states[0] = -94.533329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144896671, states[0] = -94.641875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153285203, states[0] = -94.421947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161828074, states[0] = -94.643067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170489959, states[0] = -94.615763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179250660, states[0] = -94.330845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187976576, states[0] = -94.639844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196728360, states[0] = -94.643154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205207426, states[0] = -94.150265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1213695582, states[0] = -94.642437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222170614, states[0] = -64.907806, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1230659968, states[0] = -94.641021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236809877, states[0] = -94.643130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1245410270, states[0] = -94.579247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253903418, states[0] = -94.641516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259806610, states[0] = -94.643117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1268359715, states[0] = -94.537243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277743920, states[0] = -94.643165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286501718, states[0] = -94.618966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1295252171, states[0] = -94.335273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1303990382, states[0] = -94.639254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312688460, states[0] = -94.642028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318650168, states[0] = -94.640327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327123819, states[0] = -22.428849, states[40]= 0.001374
Saving checkpoint... 
Iteration: 1335571354, states[0] = -94.632877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343996624, states[0] = -94.639009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349925316, states[0] = -94.640824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358511440, states[0] = -94.621388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1366970154, states[0] = -94.639667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375550024, states[0] = -94.629468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1384057906, states[0] = 17.126585, states[40]= 0.003011
Saving checkpoint... 
Iteration: 1392597696, states[0] = -94.635992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401129466, states[0] = -27.169941, states[40]= 0.001347
Saving checkpoint... 
Iteration: 1409553016, states[0] = -94.629914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418064992, states[0] = 14.574498, states[40]= 0.003496
Saving checkpoint... 
Iteration: 1426622969, states[0] = -94.638266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1435160390, states[0] = -54.661867, states[40]= 0.000047
Saving checkpoint... 
Iteration: 1443889715, states[0] = -94.641445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1452478711, states[0] = -94.611566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458549419, states[0] = -94.629203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1467040569, states[0] = 22.559030, states[40]= 0.001939
Saving checkpoint... 
Iteration: 1474948922, states[0] = -94.640003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1483283258, states[0] = -94.416968, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1491750225, states[0] = -94.642794, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.514554
 - CaMKt in component CaMK (millimolar): 0.004264
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.502348
 - nass in component intracellular_ions (millimolar): 6.502435
 - ki in component intracellular_ions (millimolar): 145.406898
 - kss in component intracellular_ions (millimolar): 145.406882
 - cansr in component intracellular_ions (millimolar): 1.601152
 - cajsr in component intracellular_ions (millimolar): 1.600475
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.003763
 - hf in component INa (dimensionless): 0.873115
 - hs in component INa (dimensionless): 0.873117
 - j in component INa (dimensionless): 0.873122
 - hsp in component INa (dimensionless): 0.713018
 - jp in component INa (dimensionless): 0.873126
 - mL in component INaL (dimensionless): 0.000053
 - hL in component INaL (dimensionless): 0.718688
 - hLp in component INaL (dimensionless): 0.510421
 - a in component Ito (dimensionless): 0.000640
 - iF in component Ito (dimensionless): 0.999861
 - iS in component Ito (dimensionless): 0.891609
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999861
 - iSp in component Ito (dimensionless): 0.931431
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975425
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002776
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097919
 - xs1 in component IKs (dimensionless): 0.125607
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997437
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:32:51 (10604): called boinc_finish(0)

</stderr_txt>
]]>


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