𝕏

Task 56020607

Name HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_494_2
Workunit 26345382
Created 4 Jul 2024, 14:37:44 UTC
Sent 4 Jul 2024, 14:37:46 UTC
Report deadline 7 Jul 2024, 14:37:46 UTC
Received 4 Jul 2024, 23:08:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236767
Run time 1 hours 36 min 22 sec
CPU time 1 hours 36 min 22 sec
Validate state Valid
Credit 41.21
Device peak FLOPS 3.23 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 11.15 MB
Peak swap size 6.23 MB
Peak disk usage 0.64 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_494.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_494_2_r1889010943_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162915467275_ORdGradInc_k_26-Coppini_2000-conf_494_2_r1889010943_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 19
     * GNa in INa: 105.643445
     * GNaL_b in INaL: 0.005949
     * Gto_b in Ito: 0.084233
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032291
     * GKs_b in IKs: 0.001960
     * GK1_b in IK1: 0.160288
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.762296
     * GKb_b in IKb: 0.003782
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034491
     * celltype in environment: 0.000000
     * nCL_0 in membrane: 1500.000000
     * CL_0 in membrane: 2000.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 132.000000
Starting output configuration...
Output starts at iteration 1499000000.
Num states to save: 1.
Num rates to save: 0.
Num algebraics to save: 0.
Saving checkpoint... 
Iteration: 5950073, states[0] = -94.805292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 14536960, states[0] = -94.723859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23013759, states[0] = 26.577917, states[40]= 0.014477
Saving checkpoint... 
Iteration: 31487066, states[0] = -94.651604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39890087, states[0] = -94.664646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48431595, states[0] = -94.605677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 56949474, states[0] = -94.647543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65357717, states[0] = -94.538112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 73789419, states[0] = -94.642252, states[40]= 0.000000
Saving checkpoint... 
Iteration: 79923705, states[0] = -94.637953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 88413817, states[0] = -94.576450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96744478, states[0] = -94.636167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105327302, states[0] = -94.489207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113849883, states[0] = -94.632890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119645716, states[0] = -94.630014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 131811749, states[0] = -94.631736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140211004, states[0] = -94.170021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 148736783, states[0] = -94.630845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156997854, states[0] = -94.626345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 165408193, states[0] = -94.565216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 173811747, states[0] = -94.629847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 182306027, states[0] = -94.450145, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190697196, states[0] = -94.628905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199126266, states[0] = -25.585266, states[40]= 0.001339
Saving checkpoint... 
Iteration: 207514892, states[0] = -94.608870, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215999218, states[0] = -94.625105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224478890, states[0] = -94.598310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230442019, states[0] = -94.583288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 239150491, states[0] = -46.998854, states[40]= 0.000148
Saving checkpoint... 
Iteration: 247855057, states[0] = -94.628324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 256600181, states[0] = -94.622516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265255273, states[0] = -94.330894, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273909321, states[0] = -94.627087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282404135, states[0] = -94.561230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290870469, states[0] = -94.627873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 299415591, states[0] = -94.568613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307932777, states[0] = -94.626423, states[40]= 0.000000
Saving checkpoint... 
Iteration: 316383651, states[0] = -94.545669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324846171, states[0] = -94.628228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333369168, states[0] = -94.532719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 341882151, states[0] = -94.627513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350327356, states[0] = -94.483375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358765904, states[0] = -94.628891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367262861, states[0] = -94.352397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370691733, states[0] = -94.627863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379343330, states[0] = -94.504578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 388034278, states[0] = 24.190773, states[40]= 0.001879
Saving checkpoint... 
Iteration: 396783894, states[0] = -94.628777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 405344122, states[0] = -94.505498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413904931, states[0] = -94.626873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422419471, states[0] = -94.570699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430901485, states[0] = -94.626920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439488105, states[0] = -94.600695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447973446, states[0] = -94.625092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456453208, states[0] = -94.587781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462425661, states[0] = -94.574189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470895156, states[0] = -94.626989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479385495, states[0] = -94.546871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487838171, states[0] = -94.628044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496381951, states[0] = -94.543896, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504152982, states[0] = -49.341526, states[40]= 0.000104
Saving checkpoint... 
Iteration: 512595852, states[0] = -94.621498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 518746037, states[0] = -94.628529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 527207277, states[0] = -94.140125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535753031, states[0] = -94.628535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544297678, states[0] = -94.433224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552867984, states[0] = -94.627405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561327638, states[0] = -94.483386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 569790493, states[0] = -94.628424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578274685, states[0] = -94.382826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 586638734, states[0] = -94.625012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595138656, states[0] = -36.242117, states[40]= 0.000628
Saving checkpoint... 
Iteration: 601041516, states[0] = 22.216257, states[40]= 0.002202
Saving checkpoint... 
Iteration: 609565714, states[0] = -94.617508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618052391, states[0] = 18.844790, states[40]= 0.002859
Saving checkpoint... 
Iteration: 626525438, states[0] = -94.610180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635030911, states[0] = 24.997962, states[40]= 0.001780
Saving checkpoint... 
Iteration: 642535246, states[0] = -94.612202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651097612, states[0] = -1.714179, states[40]= 0.004190
Saving checkpoint... 
Iteration: 659513773, states[0] = -94.607415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 667920002, states[0] = -94.626056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676344963, states[0] = -94.506022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686423441, states[0] = -94.572526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694868568, states[0] = -94.627136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 703353959, states[0] = -94.516381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711971581, states[0] = -94.624661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720371527, states[0] = -94.534227, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728830373, states[0] = -94.627721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737316771, states[0] = -94.466585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745653283, states[0] = -94.625588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754098187, states[0] = -2.099071, states[40]= 0.004135
Saving checkpoint... 
Iteration: 762792268, states[0] = -94.628062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 771766936, states[0] = -94.628134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780483980, states[0] = -94.598761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788479442, states[0] = -94.597242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796764155, states[0] = -94.628087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802573279, states[0] = -94.618230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811019376, states[0] = 26.843120, states[40]= 0.003382
Saving checkpoint... 
Iteration: 819458247, states[0] = -94.589249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828299960, states[0] = -94.437084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837008871, states[0] = 26.797021, states[40]= 0.070327
Saving checkpoint... 
Iteration: 845612191, states[0] = -94.622498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853542721, states[0] = -94.613255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861997959, states[0] = -94.623675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 870457675, states[0] = -94.588919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878912616, states[0] = -94.625848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887268695, states[0] = -94.367098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895730167, states[0] = -94.627696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904769307, states[0] = -94.627891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 910830598, states[0] = -94.627387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919300690, states[0] = -94.438298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 927787287, states[0] = -94.627792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936237653, states[0] = -94.272716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944649573, states[0] = -94.625022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953138728, states[0] = -36.304639, states[40]= 0.000623
Saving checkpoint... 
Iteration: 961601696, states[0] = -94.621290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970328561, states[0] = -94.483957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 979068267, states[0] = 13.100750, states[40]= 0.003901
Saving checkpoint... 
Iteration: 987813761, states[0] = -94.627460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 996530441, states[0] = -94.610577, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005076739, states[0] = 9.516485, states[40]= 0.004330
Saving checkpoint... 
Iteration: 1013641340, states[0] = -94.624403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022086429, states[0] = 4.834050, states[40]= 0.004580
Saving checkpoint... 
Iteration: 1027913045, states[0] = -94.625567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036471982, states[0] = -94.594174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044847352, states[0] = -94.626884, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1053222339, states[0] = -94.216107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061718580, states[0] = -94.627225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070250404, states[0] = -94.314507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078797526, states[0] = -94.627450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084746914, states[0] = -94.627506, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093263562, states[0] = -94.352984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101709331, states[0] = -94.626977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110190305, states[0] = -91.858844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118691768, states[0] = -94.626500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127183992, states[0] = -85.403272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1135901332, states[0] = -94.625641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1144658405, states[0] = -94.625130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1153270118, states[0] = -94.370293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162021716, states[0] = 26.620217, states[40]= 0.002363
Saving checkpoint... 
Iteration: 1170505366, states[0] = -94.604340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178978926, states[0] = -94.623615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187437655, states[0] = -94.579212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196006026, states[0] = 28.065192, states[40]= 0.180171
Saving checkpoint... 
Iteration: 1202162849, states[0] = -58.872449, states[40]= 0.000022
Saving checkpoint... 
Iteration: 1210709925, states[0] = -94.626791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1219186265, states[0] = -88.374072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225134402, states[0] = -32.537797, states[40]= 0.000924
Saving checkpoint... 
Iteration: 1233655936, states[0] = -94.624842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243031347, states[0] = 24.898840, states[40]= 0.001790
Saving checkpoint... 
Iteration: 1251736846, states[0] = -94.627123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260523216, states[0] = -94.608535, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1269235304, states[0] = -94.263856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278003022, states[0] = 37.017499, states[40]= 0.427653
Saving checkpoint... 
Iteration: 1283972110, states[0] = -94.623607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292484306, states[0] = -94.597935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300999399, states[0] = -94.622837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309413238, states[0] = -94.565279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1315323740, states[0] = -94.476301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323861455, states[0] = -94.626128, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332354008, states[0] = -94.515287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1340956498, states[0] = -94.623915, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349502512, states[0] = -94.603247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358072025, states[0] = 11.562516, states[40]= 0.004109
Saving checkpoint... 
Iteration: 1366614403, states[0] = -94.621747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375182742, states[0] = -83.563668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383675112, states[0] = -94.625443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392180762, states[0] = -80.543357, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1400710630, states[0] = -94.626460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409458422, states[0] = -94.588247, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418042398, states[0] = 21.959093, states[40]= 0.002249
Saving checkpoint... 
Iteration: 1424133573, states[0] = -31.821568, states[40]= 0.000984
Saving checkpoint... 
Iteration: 1432709307, states[0] = -94.626375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440549670, states[0] = -94.613433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1448915453, states[0] = -94.624745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457445187, states[0] = -94.582357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465919520, states[0] = -94.624617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1474310774, states[0] = -94.455338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486813415, states[0] = -94.626557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499644627, states[0] = -94.623723, states[40]= 0.000000
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -94.498397
 - CaMKt in component CaMK (millimolar): 0.004192
 - cass in component intracellular_ions (millimolar): 0.000085
 - nai in component intracellular_ions (millimolar): 6.508083
 - nass in component intracellular_ions (millimolar): 6.508169
 - ki in component intracellular_ions (millimolar): 145.404646
 - kss in component intracellular_ions (millimolar): 145.404631
 - cansr in component intracellular_ions (millimolar): 1.588609
 - cajsr in component intracellular_ions (millimolar): 1.587924
 - cai in component intracellular_ions (millimolar): 0.000087
 - m in component INa (dimensionless): 0.003769
 - hf in component INa (dimensionless): 0.872821
 - hs in component INa (dimensionless): 0.872822
 - j in component INa (dimensionless): 0.872828
 - hsp in component INa (dimensionless): 0.712475
 - jp in component INa (dimensionless): 0.872831
 - mL in component INaL (dimensionless): 0.000054
 - hL in component INaL (dimensionless): 0.718257
 - hLp in component INaL (dimensionless): 0.510097
 - a in component Ito (dimensionless): 0.000641
 - iF in component Ito (dimensionless): 0.999860
 - iS in component Ito (dimensionless): 0.892033
 - ap in component Ito (dimensionless): 0.000326
 - iFp in component Ito (dimensionless): 0.999860
 - iSp in component Ito (dimensionless): 0.931774
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.975662
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 1.000000
 - jca in component ICaL (dimensionless): 1.000000
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002701
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.097905
 - xs1 in component IKs (dimensionless): 0.124618
 - xs2 in component IKs (dimensionless): 0.000092
 - xk1 in component IK1 (dimensionless): 0.997441
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:36:15 (7828): called boinc_finish(0)

</stderr_txt>
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