𝕏

Task 56020297

Name HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2
Workunit 26337614
Created 4 Jul 2024, 14:25:07 UTC
Sent 4 Jul 2024, 14:25:10 UTC
Report deadline 7 Jul 2024, 14:25:10 UTC
Received 5 Jul 2024, 14:40:22 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241949
Run time 1 hours 3 min 49 sec
CPU time 1 hours 3 min 45 sec
Validate state Valid
Credit 48.15
Device peak FLOPS 4.24 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.30 MB
Peak swap size 6.14 MB
Peak disk usage 0.02 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2_r1331357084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2_r1331357084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.500597
     * GNaL_b in INaL: 0.006130
     * Gto_b in Ito: 0.083110
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031835
     * GKs_b in IKs: 0.001903
     * GK1_b in IK1: 0.041580
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.609697
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037696
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 8856718, states[0] = -91.752533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 21492081, states[0] = -91.641357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34125996, states[0] = -37.941476, states[40]= 0.000414
Saving checkpoint... 
Iteration: 46896785, states[0] = -91.297235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59548787, states[0] = 18.118755, states[40]= 0.002544
Saving checkpoint... 
Iteration: 72472195, states[0] = -91.344942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85067253, states[0] = 10.390066, states[40]= 0.003940
Saving checkpoint... 
Iteration: 97249896, states[0] = -89.219925, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109931385, states[0] = -91.251008, states[40]= 0.000000
Saving checkpoint... 
Iteration: 123031020, states[0] = 24.682374, states[40]= 0.001574
Saving checkpoint... 
Iteration: 136096820, states[0] = -8.591253, states[40]= 0.002886
Saving checkpoint... 
Iteration: 149072846, states[0] = 7.747990, states[40]= 0.004267
Saving checkpoint... 
Iteration: 158249959, states[0] = -89.167157, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2_r1331357084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2_r1331357084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.500597
     * GNaL_b in INaL: 0.006130
     * Gto_b in Ito: 0.083110
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031835
     * GKs_b in IKs: 0.001903
     * GK1_b in IK1: 0.041580
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.609697
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037696
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 158249959
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -89.167157 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 170678666, states[0] = -73.224581, states[40]= 0.000001
Saving checkpoint... 
Iteration: 183177279, states[0] = -72.635576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 196166683, states[0] = -67.666697, states[40]= 0.000003
Saving checkpoint... 
Iteration: 208436320, states[0] = -91.236126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 220955645, states[0] = -91.261302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233391433, states[0] = -91.141655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245930583, states[0] = -91.225865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255494532, states[0] = -91.293833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267765427, states[0] = -89.907647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280787970, states[0] = -90.454049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293013628, states[0] = 28.130643, states[40]= 0.014316
Saving checkpoint... 
Iteration: 305172940, states[0] = -70.703767, states[40]= 0.000002
Saving checkpoint... 
Iteration: 317553297, states[0] = 16.492594, states[40]= 0.002914
Saving checkpoint... 
Iteration: 330191732, states[0] = -78.099659, states[40]= 0.000001
Saving checkpoint... 
Iteration: 342742448, states[0] = -88.582730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355064599, states[0] = 11.706138, states[40]= 0.003772
Saving checkpoint... 
Iteration: 367574054, states[0] = 7.146197, states[40]= 0.004323
Saving checkpoint... 
Iteration: 380096483, states[0] = -8.222500, states[40]= 0.002968
Saving checkpoint... 
Iteration: 392517414, states[0] = 27.895286, states[40]= 0.004774
Saving checkpoint... 
Iteration: 405313561, states[0] = -90.755663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417626377, states[0] = -36.967320, states[40]= 0.000478
Saving checkpoint... 
Iteration: 427809490, states[0] = -90.718814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440094770, states[0] = -6.677746, states[40]= 0.003306
Saving checkpoint... 
Iteration: 452341289, states[0] = -90.944287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 464709643, states[0] = -83.315903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 477191670, states[0] = -78.077601, states[40]= 0.000001
Saving checkpoint... 
Iteration: 489046889, states[0] = 19.007266, states[40]= 0.002437
Saving checkpoint... 
Iteration: 501234007, states[0] = -87.709534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513850803, states[0] = -90.991945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526803208, states[0] = -90.654865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539497822, states[0] = -91.294006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 552123429, states[0] = -34.226414, states[40]= 0.000644
Saving checkpoint... 
Iteration: 564692682, states[0] = -78.416333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577573940, states[0] = 7.205754, states[40]= 0.004319
Saving checkpoint... 
Iteration: 590089923, states[0] = -2.693715, states[40]= 0.004053
Saving checkpoint... 
Iteration: 598312177, states[0] = -90.742570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 611109814, states[0] = -21.294475, states[40]= 0.001185
Saving checkpoint... 
Iteration: 623730390, states[0] = -87.244716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 636119016, states[0] = -30.090683, states[40]= 0.000909
Saving checkpoint... 
Iteration: 648400761, states[0] = -91.163147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661128687, states[0] = -39.102847, states[40]= 0.000369
Saving checkpoint... 
Iteration: 673348544, states[0] = -90.980385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685947529, states[0] = -91.248106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698693496, states[0] = -78.684503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711386257, states[0] = -91.123875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723964937, states[0] = -91.267842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 736260866, states[0] = -89.727739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748717800, states[0] = -85.130448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761100116, states[0] = -11.681574, states[40]= 0.002234
Saving checkpoint... 
Iteration: 770524673, states[0] = 26.533156, states[40]= 0.001623
Saving checkpoint... 
Iteration: 783138269, states[0] = -47.807496, states[40]= 0.000110
Saving checkpoint... 
Iteration: 795515393, states[0] = 28.067953, states[40]= 0.008351
Saving checkpoint... 
Iteration: 807912130, states[0] = -91.188226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820294224, states[0] = -90.544224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 831481347, states[0] = -91.281761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843715803, states[0] = -84.718184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 856422672, states[0] = -91.208729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868903645, states[0] = -91.169036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881071641, states[0] = 8.374851, states[40]= 0.004209
Saving checkpoint... 
Iteration: 893427107, states[0] = -91.216442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905908055, states[0] = -91.178951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918640423, states[0] = -49.687311, states[40]= 0.000083
Saving checkpoint... 
Iteration: 931236010, states[0] = -87.938906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 943224916, states[0] = -86.422951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955836412, states[0] = -90.914586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968527191, states[0] = 25.860137, states[40]= 0.001529
Saving checkpoint... 
Iteration: 981236352, states[0] = -87.976570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993827863, states[0] = -90.861242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006324934, states[0] = -90.841181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018953765, states[0] = -91.254297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031522031, states[0] = 27.143432, states[40]= 0.001994
Saving checkpoint... 
Iteration: 1044333823, states[0] = -90.898820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1057063939, states[0] = 12.003208, states[40]= 0.003725
Saving checkpoint... 
Iteration: 1069366452, states[0] = -91.055671, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081749788, states[0] = -89.137230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094243310, states[0] = -88.652013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106802440, states[0] = -90.643579, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118507943, states[0] = 28.283216, states[40]= 0.092643
Saving checkpoint... 
Iteration: 1131238214, states[0] = -88.174258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143343387, states[0] = -90.952147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1155604696, states[0] = -16.228539, states[40]= 0.001522
Saving checkpoint... 
Iteration: 1168174154, states[0] = -71.250411, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1180699753, states[0] = -80.634888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193370006, states[0] = -91.068324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205868778, states[0] = -91.063761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218983243, states[0] = -91.281393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232109366, states[0] = -20.854193, states[40]= 0.001198
Saving checkpoint... 
Iteration: 1245021488, states[0] = 27.254680, states[40]= 0.002133
Saving checkpoint... 
Iteration: 1258216435, states[0] = -84.847746, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2_r1331357084_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240701162112100363_ORdGradInc_k_26-TESZT_Block_K1_75-conf_992_2_r1331357084_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 3000000.000000
 - dt: 0.002000
 - Constants to change: 17
     * GNa in INa: 105.500597
     * GNaL_b in INaL: 0.006130
     * Gto_b in Ito: 0.083110
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031835
     * GKs_b in IKs: 0.001903
     * GK1_b in IK1: 0.041580
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.609697
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037696
     * celltype in environment: 0.000000
     * cao in extracellular: 1.800000
     * ko in extracellular: 4.000000
     * nao in extracellular: 135.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 1258216435
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -84.847746 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 1270968444, states[0] = -91.268720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1283508882, states[0] = 28.145735, states[40]= 0.067678
Saving checkpoint... 
Iteration: 1292039386, states[0] = 21.820416, states[40]= 0.001957
Saving checkpoint... 
Iteration: 1304470635, states[0] = -91.270602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1317281237, states[0] = -90.326393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330392529, states[0] = -91.138738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343014103, states[0] = 28.122602, states[40]= 0.012341
Saving checkpoint... 
Iteration: 1355743116, states[0] = -88.633772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368731038, states[0] = -87.326912, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381296548, states[0] = -90.572110, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1393767460, states[0] = -89.970161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406056774, states[0] = 15.078208, states[40]= 0.003184
Saving checkpoint... 
Iteration: 1418668914, states[0] = -68.778971, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1431348963, states[0] = -90.978824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444100008, states[0] = -11.573434, states[40]= 0.002256
Saving checkpoint... 
Iteration: 1456723600, states[0] = -86.199902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464989918, states[0] = -91.284908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1477414084, states[0] = -91.189174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1490032859, states[0] = 24.105109, states[40]= 0.001643
Total time: 3000000.000000
State Variables:
 - v in component membrane (millivolt): -91.166642
 - CaMKt in component CaMK (millimolar): 0.012299
 - cass in component intracellular_ions (millimolar): 0.000086
 - nai in component intracellular_ions (millimolar): 6.630964
 - nass in component intracellular_ions (millimolar): 6.631056
 - ki in component intracellular_ions (millimolar): 145.258146
 - kss in component intracellular_ions (millimolar): 145.258126
 - cansr in component intracellular_ions (millimolar): 1.633216
 - cajsr in component intracellular_ions (millimolar): 1.590870
 - cai in component intracellular_ions (millimolar): 0.000088
 - m in component INa (dimensionless): 0.005274
 - hf in component INa (dimensionless): 0.798782
 - hs in component INa (dimensionless): 0.798746
 - j in component INa (dimensionless): 0.798494
 - hsp in component INa (dimensionless): 0.588853
 - jp in component INa (dimensionless): 0.798293
 - mL in component INaL (dimensionless): 0.000101
 - hL in component INaL (dimensionless): 0.585945
 - hLp in component INaL (dimensionless): 0.309882
 - a in component Ito (dimensionless): 0.000802
 - iF in component Ito (dimensionless): 0.999749
 - iS in component Ito (dimensionless): 0.574361
 - ap in component Ito (dimensionless): 0.000409
 - iFp in component Ito (dimensionless): 0.999749
 - iSp in component Ito (dimensionless): 0.629399
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.914964
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999830
 - jca in component ICaL (dimensionless): 0.999972
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.002891
 - xrf in component IKr (dimensionless): 0.000005
 - xrs in component IKr (dimensionless): 0.442725
 - xs1 in component IKs (dimensionless): 0.270954
 - xs2 in component IKs (dimensionless): 0.000134
 - xk1 in component IK1 (dimensionless): 0.998160
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:38:15 (5192): called boinc_finish(0)

</stderr_txt>
]]>


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