𝕏

Task 56019483

Name HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_421_2
Workunit 26576079
Created 4 Jul 2024, 7:06:42 UTC
Sent 4 Jul 2024, 7:06:45 UTC
Report deadline 7 Jul 2024, 16:42:45 UTC
Received 4 Jul 2024, 13:40:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241597
Run time 2 hours 24 min 58 sec
CPU time 2 hours 23 min 18 sec
Validate state Valid
Credit 61.72
Device peak FLOPS 5.16 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.38 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.16.17</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_421.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_421_2_r1415995072_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240703201714455279_ORdGradInc_k_26-Pueyo_APDR-conf_421_2_r1415995072_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.723711
     * GNaL_b in INaL: 0.005901
     * Gto_b in Ito: 0.084746
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031426
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 71.458818
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031822
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15064337, states[0] = 4.494725, states[40]= 0.004670
Saving checkpoint... 
Iteration: 30828150, states[0] = -95.029707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 47104381, states[0] = -23.717960, states[40]= 0.000773
Saving checkpoint... 
Iteration: 62823815, states[0] = -94.996714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78350627, states[0] = -95.004713, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93521830, states[0] = 20.944727, states[40]= 0.008269
Saving checkpoint... 
Iteration: 108638931, states[0] = -56.721686, states[40]= 0.000009
Saving checkpoint... 
Iteration: 122546246, states[0] = 13.358375, states[40]= 0.005012
Saving checkpoint... 
Iteration: 135473838, states[0] = -95.030430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146027440, states[0] = 19.634380, states[40]= 0.006420
Saving checkpoint... 
Iteration: 159442881, states[0] = -95.024031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169800509, states[0] = -94.963791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 185314044, states[0] = -94.973353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 200534039, states[0] = 17.681808, states[40]= 0.005569
Saving checkpoint... 
Iteration: 215605421, states[0] = -23.100726, states[40]= 0.000805
Saving checkpoint... 
Iteration: 230659529, states[0] = -85.333267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 245691248, states[0] = -94.809992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260701792, states[0] = -94.832240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275724741, states[0] = -94.874399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290824085, states[0] = -94.979336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 306253519, states[0] = -94.916187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321238694, states[0] = -94.896111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336206951, states[0] = -94.842295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 351225225, states[0] = -94.875124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366181901, states[0] = -94.776672, states[40]= 0.000000
Saving checkpoint... 
Iteration: 381083549, states[0] = -4.162887, states[40]= 0.003544
Saving checkpoint... 
Iteration: 396227290, states[0] = -94.878484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411903131, states[0] = -95.013272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 426812011, states[0] = -94.971341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441849263, states[0] = -94.992948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456437480, states[0] = -95.021751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470868637, states[0] = -95.001446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 485468665, states[0] = -95.027422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499876194, states[0] = -95.004346, states[40]= 0.000000
Saving checkpoint... 
Iteration: 514493279, states[0] = -95.030854, states[40]= 0.000000
Saving checkpoint... 
Iteration: 529200530, states[0] = -94.829474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544010612, states[0] = 23.003424, states[40]= 0.045355
Saving checkpoint... 
Iteration: 558384741, states[0] = -95.007368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572677850, states[0] = -94.730704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587026892, states[0] = 19.797905, states[40]= 0.006533
Saving checkpoint... 
Iteration: 601358010, states[0] = -94.996885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 615954383, states[0] = -95.024935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630703510, states[0] = -94.835367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645033612, states[0] = 17.822456, states[40]= 0.005606
Saving checkpoint... 
Iteration: 659454385, states[0] = -95.024907, states[40]= 0.000000
Saving checkpoint... 
Iteration: 674080446, states[0] = -2.128297, states[40]= 0.003913
Saving checkpoint... 
Iteration: 688526337, states[0] = 19.943853, states[40]= 0.006657
Saving checkpoint... 
Iteration: 703266925, states[0] = -94.931624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 719477035, states[0] = -95.028534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734872204, states[0] = -95.002677, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750248449, states[0] = -94.909357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765370110, states[0] = -95.001839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779790916, states[0] = -94.954837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794255266, states[0] = -94.918025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809029380, states[0] = 19.109046, states[40]= 0.006092
Saving checkpoint... 
Iteration: 823626088, states[0] = -42.756312, states[40]= 0.000088
Saving checkpoint... 
Iteration: 838074286, states[0] = 1.401001, states[40]= 0.004397
Saving checkpoint... 
Iteration: 852889653, states[0] = -95.008826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867288956, states[0] = -94.953085, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881752862, states[0] = -94.914970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896712986, states[0] = -94.853319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911168944, states[0] = -93.920198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925563479, states[0] = 6.542329, states[40]= 0.004775
Saving checkpoint... 
Iteration: 939985793, states[0] = -95.029611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954482223, states[0] = -95.029116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969016635, states[0] = 21.970515, states[40]= 0.014084
Saving checkpoint... 
Iteration: 983372870, states[0] = -95.002772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998275129, states[0] = -94.940034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1012791323, states[0] = -94.955032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027112343, states[0] = -29.536779, states[40]= 0.000500
Saving checkpoint... 
Iteration: 1041788542, states[0] = -94.952608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1056279434, states[0] = -94.944230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070814988, states[0] = -94.972952, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085349762, states[0] = -94.992768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099623402, states[0] = -40.081158, states[40]= 0.000131
Saving checkpoint... 
Iteration: 1114290468, states[0] = -94.954234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128776036, states[0] = -94.940856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143278102, states[0] = -94.942883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1157694755, states[0] = -94.817086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171921326, states[0] = -95.017620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187013059, states[0] = 22.520286, states[40]= 0.026428
Saving checkpoint... 
Iteration: 1201564089, states[0] = 6.276095, states[40]= 0.004763
Saving checkpoint... 
Iteration: 1216249659, states[0] = -94.910640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231069489, states[0] = 3.808041, states[40]= 0.004615
Saving checkpoint... 
Iteration: 1245751163, states[0] = -94.912567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260132278, states[0] = -49.165248, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1274733056, states[0] = -94.887033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289147470, states[0] = -66.427034, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1303722488, states[0] = -94.869899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318357967, states[0] = -94.996398, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1332577761, states[0] = -0.516475, states[40]= 0.004160
Saving checkpoint... 
Iteration: 1347106708, states[0] = -24.285397, states[40]= 0.000750
Saving checkpoint... 
Iteration: 1358974668, states[0] = -95.027770, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1368714916, states[0] = -94.856542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1377700087, states[0] = -94.828018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1388569882, states[0] = 3.619512, states[40]= 0.004601
Saving checkpoint... 
Iteration: 1402037334, states[0] = 16.594650, states[40]= 0.005337
Saving checkpoint... 
Iteration: 1413943556, states[0] = -95.022369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420566721, states[0] = 5.099843, states[40]= 0.004701
Saving checkpoint... 
Iteration: 1434996313, states[0] = -95.030627, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1449718453, states[0] = -94.862817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464287289, states[0] = -94.951226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1478704665, states[0] = -94.837087, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493066064, states[0] = 5.397879, states[40]= 0.004718
Saving checkpoint... 
Iteration: 1507532912, states[0] = 16.818115, states[40]= 0.006675
Saving checkpoint... 
Iteration: 1522126727, states[0] = -95.201232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536679868, states[0] = -13.671266, states[40]= 0.001867
Saving checkpoint... 
Iteration: 1551398100, states[0] = -33.623007, states[40]= 0.000312
Saving checkpoint... 
Iteration: 1565753216, states[0] = 6.289960, states[40]= 0.005448
Saving checkpoint... 
Iteration: 1579894124, states[0] = -29.818769, states[40]= 0.000475
Saving checkpoint... 
Iteration: 1594209360, states[0] = 24.233048, states[40]= 0.060467
Saving checkpoint... 
Iteration: 1608633827, states[0] = 15.771290, states[40]= 0.006528
Saving checkpoint... 
Iteration: 1622835689, states[0] = -84.821199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1637183203, states[0] = -18.316733, states[40]= 0.001211
Saving checkpoint... 
Iteration: 1651339159, states[0] = -90.258773, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665487525, states[0] = -95.166867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679753931, states[0] = 5.722116, states[40]= 0.005412
Saving checkpoint... 
Iteration: 1693860629, states[0] = 1.735172, states[40]= 0.005020
Saving checkpoint... 
Iteration: 1707844110, states[0] = -95.258430, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721778896, states[0] = -13.744614, states[40]= 0.001862
Saving checkpoint... 
Iteration: 1735806350, states[0] = 26.844369, states[40]= 0.110708
Saving checkpoint... 
Iteration: 1749742930, states[0] = -93.413804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1763797482, states[0] = -33.738439, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1778047712, states[0] = -95.262545, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792982833, states[0] = -95.156721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807703167, states[0] = -94.878412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822325318, states[0] = -95.014102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836353320, states[0] = -95.017453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850681637, states[0] = -94.793906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865013592, states[0] = 22.361712, states[40]= 0.023662
Saving checkpoint... 
Iteration: 1879018449, states[0] = 21.609664, states[40]= 0.011133
Saving checkpoint... 
Iteration: 1893272300, states[0] = -94.940902, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1907862245, states[0] = -95.000633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923260054, states[0] = -94.924800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938619375, states[0] = -36.247846, states[40]= 0.000225
Saving checkpoint... 
Iteration: 1952727772, states[0] = -94.878951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967005021, states[0] = 28.210576, states[40]= 0.148516
Saving checkpoint... 
Iteration: 1981495492, states[0] = -95.030433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995628927, states[0] = -45.669128, states[40]= 0.000056
Saving checkpoint... 
Iteration: 2009969109, states[0] = -95.026578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024043236, states[0] = 14.511861, states[40]= 0.005086
Saving checkpoint... 
Iteration: 2038369531, states[0] = -95.000781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2052446023, states[0] = -95.022419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066532145, states[0] = 18.283152, states[40]= 0.005748
Saving checkpoint... 
Iteration: 2080920578, states[0] = -95.016803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095014575, states[0] = 22.286419, states[40]= 0.019698
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.906459
 - CaMKt in component CaMK (millimolar): 0.007044
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.547129
 - nass in component intracellular_ions (millimolar): 6.547189
 - ki in component intracellular_ions (millimolar): 145.429748
 - kss in component intracellular_ions (millimolar): 145.429729
 - cansr in component intracellular_ions (millimolar): 1.314513
 - cajsr in component intracellular_ions (millimolar): 1.276275
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003617
 - hf in component INa (dimensionless): 0.880081
 - hs in component INa (dimensionless): 0.880076
 - j in component INa (dimensionless): 0.880047
 - hsp in component INa (dimensionless): 0.725981
 - jp in component INa (dimensionless): 0.880027
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709556
 - hLp in component INaL (dimensionless): 0.450706
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619184
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.693651
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933882
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001612
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332179
 - xs1 in component IKs (dimensionless): 0.244753
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:34:04 (961980): called boinc_finish(0)

</stderr_txt>
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