𝕏

Task 56018056

Name HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0
Workunit 26603273
Created 4 Jul 2024, 2:50:49 UTC
Sent 4 Jul 2024, 3:07:42 UTC
Report deadline 7 Jul 2024, 12:43:42 UTC
Received 8 Jul 2024, 0:35:01 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215737
Run time 1 hours 6 min 49 sec
CPU time 52 min 34 sec
Validate state Valid
Credit 60.66
Device peak FLOPS 4.76 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.72 MB
Peak swap size 391.76 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 33247218, states[0] = -94.935239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59652167, states[0] = -79.526792, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86278944, states[0] = -94.938158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112584954, states[0] = -6.862900, states[40]= 0.003014
Saving checkpoint... 
Iteration: 151094226, states[0] = -14.842364, states[40]= 0.001493
Saving checkpoint... 
Iteration: 189576226, states[0] = -0.781037, states[40]= 0.004156
Saving checkpoint... 
Iteration: 231623237, states[0] = -42.650342, states[40]= 0.000087


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 231623237
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -42.650342 (After loading)
 - states[40]: 0.000087 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 269410187, states[0] = -95.000965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307188505, states[0] = -94.789570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340757227, states[0] = -94.906518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 368088063, states[0] = -9.238155, states[40]= 0.002501
Saving checkpoint... 
Iteration: 397924008, states[0] = -95.004361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428776380, states[0] = -94.927388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451700278, states[0] = -94.814853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475160343, states[0] = -90.212217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 503920183, states[0] = -95.003365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528484662, states[0] = -95.015319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554243182, states[0] = -94.888202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583845168, states[0] = -94.976456, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 583845168
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.976456 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 593535894, states[0] = 16.642425, states[40]= 0.005519
Saving checkpoint... 
Iteration: 626080481, states[0] = -3.454923, states[40]= 0.003709
Saving checkpoint... 
Iteration: 643836754, states[0] = -94.972033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 670143854, states[0] = -65.381102, states[40]= 0.000002
Saving checkpoint... 
Iteration: 684051398, states[0] = 10.829930, states[40]= 0.004978
Saving checkpoint... 
Iteration: 715358572, states[0] = -94.982664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750994478, states[0] = -95.016444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 788720152, states[0] = -94.852155, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823016530, states[0] = 21.854325, states[40]= 0.014541
Saving checkpoint... 
Iteration: 860187851, states[0] = -94.787613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 895254325, states[0] = -94.902613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932082071, states[0] = -4.555968, states[40]= 0.003495
Saving checkpoint... 
Iteration: 967883674, states[0] = -94.992333, states[40]= 0.000000


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704045044104027_ORdGradInc_k_26-Pueyo_APDR-conf_377_0_r1259085298_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.999785
     * GNaL_b in INaL: 0.005568
     * Gto_b in Ito: 0.083066
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031801
     * GKs_b in IKs: 0.001894
     * GK1_b in IK1: 0.162768
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.821232
     * GKb_b in IKb: 0.003832
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030344
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Loading checkpoint...
Loading iteration number...
 - Iteration number: 967883674
Loading states...
 - states[0]: -87.000000 (Before loading)
 - states[40]: 0.000000 (Before loading)
 - states[0]: -94.992333 (After loading)
 - states[40]: 0.000000 (After loading)
Loading output...
Loading postprocessing...
Loading startTime...
Loading startAP...
Loading num AP...
Loading last results...
Postprocessing loaded.
Simulation loaded.
Checkpoint loaded.
Saving checkpoint... 
Iteration: 970073544, states[0] = 0.760088, states[40]= 0.004360
Saving checkpoint... 
Iteration: 1005185534, states[0] = -94.781458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017277708, states[0] = -94.928315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1020463419, states[0] = -95.011826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028409425, states[0] = -95.000237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052940876, states[0] = -95.007663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078231433, states[0] = -94.870556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103823108, states[0] = -94.963822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1123198665, states[0] = -94.811121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147730256, states[0] = -94.868664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174992577, states[0] = -95.015938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1200444010, states[0] = -95.008198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1225187216, states[0] = -94.785793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249114339, states[0] = -33.877426, states[40]= 0.000299
Saving checkpoint... 
Iteration: 1274972909, states[0] = -95.013163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309001475, states[0] = 48.210540, states[40]= 0.059455
Saving checkpoint... 
Iteration: 1340309731, states[0] = -94.954809, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1364433540, states[0] = -95.005918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383066940, states[0] = 4.134248, states[40]= 0.004679
Saving checkpoint... 
Iteration: 1411417847, states[0] = -95.002203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434320282, states[0] = -94.961834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1454602955, states[0] = -23.037396, states[40]= 0.000797
Saving checkpoint... 
Iteration: 1487077522, states[0] = -1.549787, states[40]= 0.004039
Saving checkpoint... 
Iteration: 1516943728, states[0] = -93.461845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1540486457, states[0] = -95.267163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562102280, states[0] = 43.239610, states[40]= 0.083154
Saving checkpoint... 
Iteration: 1596347933, states[0] = 8.410992, states[40]= 0.005677
Saving checkpoint... 
Iteration: 1629313129, states[0] = 22.840452, states[40]= 0.027935
Saving checkpoint... 
Iteration: 1660799956, states[0] = -95.296406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697525236, states[0] = -70.383549, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1732046881, states[0] = -94.801523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776715152, states[0] = -56.718212, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1817060262, states[0] = 6.279125, states[40]= 0.004857
Saving checkpoint... 
Iteration: 1856720597, states[0] = -94.865766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897573387, states[0] = 0.733646, states[40]= 0.004361
Saving checkpoint... 
Iteration: 1938490522, states[0] = -95.016333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976097581, states[0] = -17.961774, states[40]= 0.001132
Saving checkpoint... 
Iteration: 2009514601, states[0] = 22.193476, states[40]= 0.019885
Saving checkpoint... 
Iteration: 2050053894, states[0] = 9.827079, states[40]= 0.004942
Saving checkpoint... 
Iteration: 2088909462, states[0] = -94.999529, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.892077
 - CaMKt in component CaMK (millimolar): 0.006963
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.592156
 - nass in component intracellular_ions (millimolar): 6.592216
 - ki in component intracellular_ions (millimolar): 145.385265
 - kss in component intracellular_ions (millimolar): 145.385246
 - cansr in component intracellular_ions (millimolar): 1.312657
 - cajsr in component intracellular_ions (millimolar): 1.274801
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003622
 - hf in component INa (dimensionless): 0.879831
 - hs in component INa (dimensionless): 0.879826
 - j in component INa (dimensionless): 0.879797
 - hsp in component INa (dimensionless): 0.725510
 - jp in component INa (dimensionless): 0.879778
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709816
 - hLp in component INaL (dimensionless): 0.452179
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.622017
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.697050
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936066
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001606
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330145
 - xs1 in component IKs (dimensionless): 0.239624
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997340
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:34:50 (902): called boinc_finish(0)

</stderr_txt>
]]>


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