𝕏

Task 56017572

Name HuVeMOp_20240704043545061620_ORdGradInc_k_26-Pueyo_APDR-conf_476_1
Workunit 26603035
Created 4 Jul 2024, 2:35:48 UTC
Sent 4 Jul 2024, 3:01:28 UTC
Report deadline 7 Jul 2024, 12:37:28 UTC
Received 4 Jul 2024, 7:25:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215734
Run time 2 hours 50 min 13 sec
CPU time 2 hours 42 min 5 sec
Validate state Valid
Credit 61.16
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 5.25 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704043545061620_ORdGradInc_k_26-Pueyo_APDR-conf_476.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704043545061620_ORdGradInc_k_26-Pueyo_APDR-conf_476_1_r1261485142_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704043545061620_ORdGradInc_k_26-Pueyo_APDR-conf_476_1_r1261485142_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.733543
     * GNaL_b in INaL: 0.005647
     * Gto_b in Ito: 0.087343
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032072
     * GKs_b in IKs: 0.001895
     * GK1_b in IK1: 0.166402
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.324268
     * GKb_b in IKb: 0.003829
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030646
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9495428, states[0] = -95.170467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23195964, states[0] = -94.925242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36930009, states[0] = -95.096598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50617855, states[0] = -38.314559, states[40]= 0.000165
Saving checkpoint... 
Iteration: 64272048, states[0] = -94.993435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 78005097, states[0] = 27.535743, states[40]= 0.150524
Saving checkpoint... 
Iteration: 91827829, states[0] = -95.027780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105638022, states[0] = -58.449412, states[40]= 0.000007
Saving checkpoint... 
Iteration: 119519644, states[0] = 21.002744, states[40]= 0.009770
Saving checkpoint... 
Iteration: 133429535, states[0] = -95.060824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147348994, states[0] = -95.033225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161252872, states[0] = -94.956249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175033410, states[0] = 17.445234, states[40]= 0.005583
Saving checkpoint... 
Iteration: 188897145, states[0] = -95.050667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 202630053, states[0] = -49.276864, states[40]= 0.000031
Saving checkpoint... 
Iteration: 216261620, states[0] = -94.965897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229994988, states[0] = -95.069814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243527110, states[0] = 19.316797, states[40]= 0.006428
Saving checkpoint... 
Iteration: 257133062, states[0] = -52.531039, states[40]= 0.000018
Saving checkpoint... 
Iteration: 270911572, states[0] = -95.054336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 280527807, states[0] = 19.127702, states[40]= 0.006295
Saving checkpoint... 
Iteration: 294203047, states[0] = -94.875203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 307918509, states[0] = -95.056066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321788874, states[0] = -94.992738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335561505, states[0] = 6.821266, states[40]= 0.004780
Saving checkpoint... 
Iteration: 349142519, states[0] = -63.366556, states[40]= 0.000003
Saving checkpoint... 
Iteration: 362821582, states[0] = -95.016749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 376428792, states[0] = -95.058445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 390202103, states[0] = -94.873239, states[40]= 0.000000
Saving checkpoint... 
Iteration: 403955814, states[0] = -95.063820, states[40]= 0.000000
Saving checkpoint... 
Iteration: 417916736, states[0] = -95.055538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 431775912, states[0] = -94.980712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 445778959, states[0] = -94.983654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 459708765, states[0] = -94.886195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 473426107, states[0] = -95.057765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 487166229, states[0] = -93.982900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501052837, states[0] = 10.394077, states[40]= 0.004891
Saving checkpoint... 
Iteration: 514962981, states[0] = -95.064963, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528839428, states[0] = -95.026827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 542466647, states[0] = -95.065537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551874242, states[0] = -95.042293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565773365, states[0] = -94.978084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579502503, states[0] = 40.222295, states[40]= 0.119574
Saving checkpoint... 
Iteration: 592760688, states[0] = -94.964397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606082974, states[0] = -4.807256, states[40]= 0.003423
Saving checkpoint... 
Iteration: 619967131, states[0] = -95.065562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 633799193, states[0] = -95.000971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647654266, states[0] = -80.837942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661479340, states[0] = -95.067357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671228880, states[0] = -94.921140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685046762, states[0] = 12.735977, states[40]= 0.004976
Saving checkpoint... 
Iteration: 698930674, states[0] = -95.058649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712559904, states[0] = 7.507576, states[40]= 0.004805
Saving checkpoint... 
Iteration: 726654796, states[0] = -81.781693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740744785, states[0] = -94.944436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 754351661, states[0] = -95.032711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767530597, states[0] = 18.325336, states[40]= 0.005877
Saving checkpoint... 
Iteration: 781039885, states[0] = 15.259680, states[40]= 0.005176
Saving checkpoint... 
Iteration: 794425841, states[0] = -95.057489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807661184, states[0] = -91.231204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 820825199, states[0] = -95.018652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834447546, states[0] = -95.062023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848128953, states[0] = -48.076604, states[40]= 0.000038
Saving checkpoint... 
Iteration: 862185173, states[0] = -94.835618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875577956, states[0] = -1.482719, states[40]= 0.004022
Saving checkpoint... 
Iteration: 889010972, states[0] = 22.474245, states[40]= 0.041935
Saving checkpoint... 
Iteration: 902833738, states[0] = -95.023518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916810131, states[0] = -95.008833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926442831, states[0] = -95.061047, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940382960, states[0] = -95.045174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954241681, states[0] = -94.940025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968030614, states[0] = 18.320285, states[40]= 0.005875
Saving checkpoint... 
Iteration: 981717667, states[0] = -94.902159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 995229066, states[0] = -94.921217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1008950269, states[0] = -95.062417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022472718, states[0] = -95.066154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031871704, states[0] = -95.041009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045024502, states[0] = 19.985301, states[40]= 0.007088
Saving checkpoint... 
Iteration: 1058394861, states[0] = -95.048989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071652156, states[0] = -77.155383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085305525, states[0] = -95.005437, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1098026652, states[0] = 19.440022, states[40]= 0.006524
Saving checkpoint... 
Iteration: 1111476023, states[0] = -95.066583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1124608645, states[0] = -27.895706, states[40]= 0.000568
Saving checkpoint... 
Iteration: 1137224790, states[0] = -94.914209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150263547, states[0] = -94.967263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1163981138, states[0] = -95.067274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177208626, states[0] = -94.885448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190998716, states[0] = -95.069500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204942717, states[0] = -95.060839, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218517638, states[0] = 21.386255, states[40]= 0.012213
Saving checkpoint... 
Iteration: 1232555036, states[0] = 9.517664, states[40]= 0.004866
Saving checkpoint... 
Iteration: 1246625568, states[0] = -44.506567, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1260101881, states[0] = -21.480787, states[40]= 0.000875
Saving checkpoint... 
Iteration: 1272856826, states[0] = -95.034708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286368551, states[0] = -95.039609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300439780, states[0] = -95.060185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314392229, states[0] = -95.047994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1327586536, states[0] = -7.515905, states[40]= 0.002853
Saving checkpoint... 
Iteration: 1339689517, states[0] = -94.846049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1344191426, states[0] = -94.850321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358011063, states[0] = 22.453845, states[40]= 0.041061
Saving checkpoint... 
Iteration: 1371543313, states[0] = 14.020171, states[40]= 0.005056
Saving checkpoint... 
Iteration: 1385548170, states[0] = 12.202794, states[40]= 0.004952
Saving checkpoint... 
Iteration: 1399322418, states[0] = -95.016572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412980980, states[0] = -95.067086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1426490076, states[0] = -95.068287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1440001412, states[0] = 48.344867, states[40]= 0.056556
Saving checkpoint... 
Iteration: 1453215414, states[0] = -94.897831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466451899, states[0] = -95.062411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475843540, states[0] = -95.028302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488915995, states[0] = -95.054635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502160879, states[0] = 2.567019, states[40]= 0.004936
Saving checkpoint... 
Iteration: 1514905456, states[0] = -95.197186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528386481, states[0] = -95.173140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1541651002, states[0] = -95.283292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554860988, states[0] = -95.300066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1568426756, states[0] = 18.340790, states[40]= 0.007591
Saving checkpoint... 
Iteration: 1581138433, states[0] = -91.767335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1594141130, states[0] = -95.288147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607239532, states[0] = -92.802481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620263851, states[0] = -95.313957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633283470, states[0] = -20.231765, states[40]= 0.001026
Saving checkpoint... 
Iteration: 1646516647, states[0] = -58.461490, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1659733334, states[0] = -84.949989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1673248664, states[0] = -94.989529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686073929, states[0] = -10.001101, states[40]= 0.002640
Saving checkpoint... 
Iteration: 1698862211, states[0] = -95.313757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712330548, states[0] = -95.278253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725232881, states[0] = -95.281333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738407371, states[0] = -95.243059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751498079, states[0] = -36.345213, states[40]= 0.000217
Saving checkpoint... 
Iteration: 1764488419, states[0] = -95.206721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1777512929, states[0] = 22.517740, states[40]= 0.028721
Saving checkpoint... 
Iteration: 1791050966, states[0] = 6.790935, states[40]= 0.005492
Saving checkpoint... 
Iteration: 1805060423, states[0] = 6.015309, states[40]= 0.004851
Saving checkpoint... 
Iteration: 1818794946, states[0] = -95.035446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831745035, states[0] = -94.971313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845520299, states[0] = 20.736353, states[40]= 0.009149
Saving checkpoint... 
Iteration: 1858735127, states[0] = -94.942327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871964782, states[0] = -95.072479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885019396, states[0] = 21.026818, states[40]= 0.009997
Saving checkpoint... 
Iteration: 1897970941, states[0] = -95.069025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911343809, states[0] = -95.030644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1924385300, states[0] = -95.046993, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1937804340, states[0] = -95.005113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951277595, states[0] = -94.982070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964023572, states[0] = 20.200709, states[40]= 0.007410
Saving checkpoint... 
Iteration: 1977083310, states[0] = -5.064313, states[40]= 0.003371
Saving checkpoint... 
Iteration: 1990299325, states[0] = -95.000357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003582770, states[0] = -4.667362, states[40]= 0.003451
Saving checkpoint... 
Iteration: 2016885887, states[0] = -95.045508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2029951758, states[0] = -95.062027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2043327619, states[0] = -95.019264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057287039, states[0] = -94.989947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070442218, states[0] = -95.060127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083469458, states[0] = -95.064906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096629025, states[0] = -48.153319, states[40]= 0.000038
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.944870
 - CaMKt in component CaMK (millimolar): 0.007048
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.548240
 - nass in component intracellular_ions (millimolar): 6.548301
 - ki in component intracellular_ions (millimolar): 145.428097
 - kss in component intracellular_ions (millimolar): 145.428077
 - cansr in component intracellular_ions (millimolar): 1.316158
 - cajsr in component intracellular_ions (millimolar): 1.278098
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880745
 - hs in component INa (dimensionless): 0.880741
 - j in component INa (dimensionless): 0.880712
 - hsp in component INa (dimensionless): 0.727235
 - jp in component INa (dimensionless): 0.880693
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711178
 - hLp in component INaL (dimensionless): 0.453678
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.621986
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.697150
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936001
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.327168
 - xs1 in component IKs (dimensionless): 0.240706
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:37:49 (7388): called boinc_finish(0)

</stderr_txt>
]]>


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