𝕏

Task 56016906

Name HuVeMOp_20240704042042026004_ORdGradInc_k_26-Pueyo_APDR-conf_393_0
Workunit 26602712
Created 4 Jul 2024, 2:20:47 UTC
Sent 4 Jul 2024, 2:57:30 UTC
Report deadline 7 Jul 2024, 12:33:30 UTC
Received 4 Jul 2024, 7:28:08 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241770
Run time 2 hours 35 min 41 sec
CPU time 2 hours 15 min 5 sec
Validate state Valid
Credit 63.37
Device peak FLOPS 3.50 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.63 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.18.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704042042026004_ORdGradInc_k_26-Pueyo_APDR-conf_393.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704042042026004_ORdGradInc_k_26-Pueyo_APDR-conf_393_0_r1535984368_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704042042026004_ORdGradInc_k_26-Pueyo_APDR-conf_393_0_r1535984368_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.793632
     * GNaL_b in INaL: 0.006008
     * Gto_b in Ito: 0.084383
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031468
     * GKs_b in IKs: 0.001893
     * GK1_b in IK1: 0.161575
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.655673
     * GKb_b in IKb: 0.003804
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.031089
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14292062, states[0] = -95.033225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 28545090, states[0] = 13.056396, states[40]= 0.005066
Saving checkpoint... 
Iteration: 42816611, states[0] = -94.997052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57174048, states[0] = -94.660829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71452586, states[0] = -95.029617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85671351, states[0] = -94.399985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99978618, states[0] = -95.026363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114102646, states[0] = -20.831785, states[40]= 0.000923
Saving checkpoint... 
Iteration: 128307288, states[0] = -94.961013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142384632, states[0] = -95.000357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156599844, states[0] = -18.075666, states[40]= 0.001121
Saving checkpoint... 
Iteration: 170744392, states[0] = -94.894104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184894211, states[0] = -95.002388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 199049286, states[0] = 12.226612, states[40]= 0.004980
Saving checkpoint... 
Iteration: 213233867, states[0] = -94.878005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227334515, states[0] = -94.976290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 241558219, states[0] = 8.711290, states[40]= 0.004871
Saving checkpoint... 
Iteration: 255664720, states[0] = -91.681217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269812617, states[0] = -94.962335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284070169, states[0] = 3.420543, states[40]= 0.004598
Saving checkpoint... 
Iteration: 298283145, states[0] = -94.938218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312446500, states[0] = -95.015125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 326614309, states[0] = -31.486505, states[40]= 0.000409
Saving checkpoint... 
Iteration: 340862303, states[0] = -94.989890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355054127, states[0] = 10.357119, states[40]= 0.004918
Saving checkpoint... 
Iteration: 369203362, states[0] = -94.823097, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383466179, states[0] = -95.018611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 397648995, states[0] = -68.468094, states[40]= 0.000001
Saving checkpoint... 
Iteration: 411755812, states[0] = -94.908350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425945620, states[0] = -95.014867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440157718, states[0] = -82.029979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454316305, states[0] = -94.964720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468551725, states[0] = 11.295746, states[40]= 0.004946
Saving checkpoint... 
Iteration: 482764293, states[0] = -94.918448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496907590, states[0] = -95.005755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511101971, states[0] = -19.994754, states[40]= 0.000975
Saving checkpoint... 
Iteration: 525292951, states[0] = -94.946869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539550670, states[0] = 11.702611, states[40]= 0.004960
Saving checkpoint... 
Iteration: 553781053, states[0] = -94.936038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567955212, states[0] = -95.016597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582150293, states[0] = -70.238520, states[40]= 0.000001
Saving checkpoint... 
Iteration: 596308491, states[0] = -94.959126, states[40]= 0.000000
Saving checkpoint... 
Iteration: 610454711, states[0] = -95.016478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624734337, states[0] = -94.878260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638891957, states[0] = -95.000898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653111159, states[0] = -28.538447, states[40]= 0.000551
Saving checkpoint... 
Iteration: 667363581, states[0] = -94.990223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 681667368, states[0] = -93.279871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 695889389, states[0] = -95.000010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 710245625, states[0] = -94.894751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724531786, states[0] = 18.384240, states[40]= 0.005822
Saving checkpoint... 
Iteration: 738864092, states[0] = -94.990395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 753182255, states[0] = -94.763462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767496223, states[0] = -95.022649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 781866551, states[0] = -94.991403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 796166611, states[0] = -92.922351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 810470754, states[0] = -95.019067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824703404, states[0] = -94.822882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839023714, states[0] = 20.598052, states[40]= 0.007484
Saving checkpoint... 
Iteration: 853312861, states[0] = -94.962088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867569860, states[0] = 3.570997, states[40]= 0.004610
Saving checkpoint... 
Iteration: 881871872, states[0] = -94.993499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896150707, states[0] = -70.819783, states[40]= 0.000001
Saving checkpoint... 
Iteration: 910398996, states[0] = -95.002954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 924566839, states[0] = 4.991427, states[40]= 0.004708
Saving checkpoint... 
Iteration: 938831791, states[0] = -94.974130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 953122892, states[0] = -39.685494, states[40]= 0.000139
Saving checkpoint... 
Iteration: 967348581, states[0] = -94.983123, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981613263, states[0] = -30.504935, states[40]= 0.000455
Saving checkpoint... 
Iteration: 995799577, states[0] = -94.952044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010011022, states[0] = 22.968705, states[40]= 0.041496
Saving checkpoint... 
Iteration: 1024291699, states[0] = -94.945467, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038403048, states[0] = -95.004090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052636970, states[0] = -54.320583, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1066722389, states[0] = -94.858368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080758407, states[0] = -94.911112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094938074, states[0] = -95.012880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1109043969, states[0] = 14.219828, states[40]= 0.005089
Saving checkpoint... 
Iteration: 1123183736, states[0] = -94.771979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137354333, states[0] = -94.985778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151607758, states[0] = -25.371820, states[40]= 0.000702
Saving checkpoint... 
Iteration: 1165788796, states[0] = -94.942824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1179953574, states[0] = -95.015901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194197372, states[0] = -94.810199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208354058, states[0] = -94.985604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1222448081, states[0] = -95.014833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236681125, states[0] = -94.754336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250789625, states[0] = -94.943505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264846746, states[0] = -94.982014, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278839749, states[0] = -94.978363, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1292839412, states[0] = -94.978173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306880025, states[0] = -94.996329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320924889, states[0] = -95.009743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334938577, states[0] = -95.012831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348927147, states[0] = -95.010263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362834149, states[0] = -94.975211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376755197, states[0] = -94.906951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390653515, states[0] = -75.008708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404480280, states[0] = -95.020113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418357294, states[0] = -94.986962, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432181824, states[0] = -94.759914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446064686, states[0] = 5.961896, states[40]= 0.004762
Saving checkpoint... 
Iteration: 1459931881, states[0] = -95.011284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473844048, states[0] = -94.980504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487743362, states[0] = -94.891074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501596254, states[0] = -28.469903, states[40]= 0.000509
Saving checkpoint... 
Iteration: 1515519584, states[0] = -95.178965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529271798, states[0] = -95.095619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543118714, states[0] = -95.201639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556990934, states[0] = -95.286719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570828253, states[0] = 18.148308, states[40]= 0.007370
Saving checkpoint... 
Iteration: 1584643468, states[0] = 11.250838, states[40]= 0.005875
Saving checkpoint... 
Iteration: 1598607472, states[0] = -95.198961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612311051, states[0] = -49.047748, states[40]= 0.000035
Saving checkpoint... 
Iteration: 1626030204, states[0] = 17.283513, states[40]= 0.007022
Saving checkpoint... 
Iteration: 1639723151, states[0] = -95.226888, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653371383, states[0] = -6.421122, states[40]= 0.003492
Saving checkpoint... 
Iteration: 1667174822, states[0] = -9.670728, states[40]= 0.002716
Saving checkpoint... 
Iteration: 1680897140, states[0] = -95.302975, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694541522, states[0] = -92.402626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1708224361, states[0] = 19.530577, states[40]= 0.008411
Saving checkpoint... 
Iteration: 1721988495, states[0] = -95.297065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735624990, states[0] = -66.868350, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1749254185, states[0] = -95.266778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762977394, states[0] = -95.139076, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776596904, states[0] = -95.302945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1790222203, states[0] = -63.052844, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1803861918, states[0] = -95.045474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1817554793, states[0] = 9.327139, states[40]= 0.004934
Saving checkpoint... 
Iteration: 1831255214, states[0] = -94.935217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1844949942, states[0] = -95.033715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858589068, states[0] = -8.996866, states[40]= 0.002544
Saving checkpoint... 
Iteration: 1872238929, states[0] = -94.892988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885811656, states[0] = -94.966211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899031297, states[0] = 18.488230, states[40]= 0.005875
Saving checkpoint... 
Iteration: 1912606596, states[0] = -24.438543, states[40]= 0.000745
Saving checkpoint... 
Iteration: 1926240866, states[0] = -94.888908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939873937, states[0] = -94.994719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953596659, states[0] = -15.108935, states[40]= 0.001449
Saving checkpoint... 
Iteration: 1967263246, states[0] = -94.916743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980902662, states[0] = -95.003653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1994518216, states[0] = 21.729507, states[40]= 0.011552
Saving checkpoint... 
Iteration: 2008293909, states[0] = -94.946819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022104724, states[0] = -22.558820, states[40]= 0.000833
Saving checkpoint... 
Iteration: 2035854259, states[0] = -94.985172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2049579243, states[0] = -1.469029, states[40]= 0.004029
Saving checkpoint... 
Iteration: 2063307589, states[0] = -94.957483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2077070218, states[0] = 3.397357, states[40]= 0.004597
Saving checkpoint... 
Iteration: 2090834025, states[0] = -94.974624, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.898072
 - CaMKt in component CaMK (millimolar): 0.007046
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.566259
 - nass in component intracellular_ions (millimolar): 6.566319
 - ki in component intracellular_ions (millimolar): 145.410492
 - kss in component intracellular_ions (millimolar): 145.410472
 - cansr in component intracellular_ions (millimolar): 1.315336
 - cajsr in component intracellular_ions (millimolar): 1.277123
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879935
 - hs in component INa (dimensionless): 0.879930
 - j in component INa (dimensionless): 0.879901
 - hsp in component INa (dimensionless): 0.725706
 - jp in component INa (dimensionless): 0.879881
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709299
 - hLp in component INaL (dimensionless): 0.450344
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.619157
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.693586
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933941
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001616
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333603
 - xs1 in component IKs (dimensionless): 0.244492
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:31:37 (1886973): called boinc_finish(0)

</stderr_txt>
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