𝕏

Task 56016728

Name HuVeMOp_20240704041544791018_ORdGradInc_k_26-Pueyo_APDR-conf_360_1
Workunit 26602623
Created 4 Jul 2024, 2:15:50 UTC
Sent 4 Jul 2024, 2:59:24 UTC
Report deadline 7 Jul 2024, 12:35:24 UTC
Received 4 Jul 2024, 12:35:19 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 229984
Run time 1 hours 14 min 32 sec
CPU time 1 hours 10 min 54 sec
Validate state Valid
Credit 63.67
Device peak FLOPS 3.84 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.26 MB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704041544791018_ORdGradInc_k_26-Pueyo_APDR-conf_360.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704041544791018_ORdGradInc_k_26-Pueyo_APDR-conf_360_1_r695976335_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704041544791018_ORdGradInc_k_26-Pueyo_APDR-conf_360_1_r695976335_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.791177
     * GNaL_b in INaL: 0.006167
     * Gto_b in Ito: 0.087397
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031715
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.167171
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.236720
     * GKb_b in IKb: 0.003779
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030293
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12982991, states[0] = -95.153889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 31333451, states[0] = -95.071328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 49837965, states[0] = -95.055246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68428751, states[0] = -95.077755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 86788095, states[0] = -95.005542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105481744, states[0] = -95.078589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 124212722, states[0] = -94.901608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143036089, states[0] = 16.949041, states[40]= 0.005394
Saving checkpoint... 
Iteration: 161366091, states[0] = -95.046261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 179699888, states[0] = -94.874639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198164945, states[0] = -92.665573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 216699191, states[0] = -94.872866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235248487, states[0] = -94.955274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253499092, states[0] = -95.076459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271721980, states[0] = -94.915411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290066968, states[0] = 5.004877, states[40]= 0.004699
Saving checkpoint... 
Iteration: 308810562, states[0] = -95.015419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327440309, states[0] = -95.067129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345917175, states[0] = -95.061851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 364645023, states[0] = -63.914861, states[40]= 0.000003
Saving checkpoint... 
Iteration: 383143303, states[0] = -61.811570, states[40]= 0.000004
Saving checkpoint... 
Iteration: 401364611, states[0] = -95.044661, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419975872, states[0] = -95.073240, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438697407, states[0] = -94.868881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 457517325, states[0] = 21.700678, states[40]= 0.012821
Saving checkpoint... 
Iteration: 476026977, states[0] = 19.682497, states[40]= 0.006482
Saving checkpoint... 
Iteration: 494534256, states[0] = 17.562564, states[40]= 0.005529
Saving checkpoint... 
Iteration: 512781012, states[0] = -94.991261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531455476, states[0] = -95.069874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 550181625, states[0] = -94.824830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568888131, states[0] = -95.053269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587550299, states[0] = 11.880743, states[40]= 0.004938
Saving checkpoint... 
Iteration: 606112751, states[0] = -29.966098, states[40]= 0.000484
Saving checkpoint... 
Iteration: 624684756, states[0] = -94.838323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 642993260, states[0] = -95.075440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661468321, states[0] = -95.071933, states[40]= 0.000000
Saving checkpoint... 
Iteration: 680048599, states[0] = 12.522357, states[40]= 0.004961
Saving checkpoint... 
Iteration: 698768886, states[0] = -94.979004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717300074, states[0] = -95.007416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735619911, states[0] = -36.768981, states[40]= 0.000212
Saving checkpoint... 
Iteration: 753939991, states[0] = -95.066774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 772416267, states[0] = -95.061333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791063742, states[0] = 6.446196, states[40]= 0.004773
Saving checkpoint... 
Iteration: 809779046, states[0] = -94.989196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828384990, states[0] = -95.052040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846751225, states[0] = -94.958308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 862288092, states[0] = -94.997448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 880705100, states[0] = -94.884066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899348344, states[0] = -95.037054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917918897, states[0] = -95.061898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 936354893, states[0] = -95.040094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 954691518, states[0] = -94.855919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 973038600, states[0] = 16.126501, states[40]= 0.005250
Saving checkpoint... 
Iteration: 991745326, states[0] = -94.950460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010184379, states[0] = -94.836751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028666222, states[0] = -93.328520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047362712, states[0] = -95.043438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065879808, states[0] = -95.050071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084736855, states[0] = -94.938426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1103204409, states[0] = -94.882561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1121793273, states[0] = -95.001690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140326541, states[0] = -95.025174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1158831320, states[0] = -95.027946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1177270893, states[0] = -94.980798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1195779238, states[0] = -94.989122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214428414, states[0] = -95.063967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232980317, states[0] = -95.073336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251564447, states[0] = 6.137358, states[40]= 0.004759
Saving checkpoint... 
Iteration: 1270206487, states[0] = -94.886505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288547877, states[0] = 12.792608, states[40]= 0.004972
Saving checkpoint... 
Iteration: 1301444440, states[0] = -95.067302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1319969495, states[0] = -95.071678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1338658842, states[0] = -85.397860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1357318262, states[0] = -95.019885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376041623, states[0] = 15.073130, states[40]= 0.005124
Saving checkpoint... 
Iteration: 1394626515, states[0] = -43.325860, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1413112251, states[0] = -29.496340, states[40]= 0.000506
Saving checkpoint... 
Iteration: 1431834239, states[0] = -95.029403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1450300124, states[0] = -95.006966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1468692735, states[0] = -94.858271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1487046453, states[0] = 13.321431, states[40]= 0.004997
Saving checkpoint... 
Iteration: 1505655819, states[0] = -95.259624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1524144947, states[0] = -93.755691, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1542655763, states[0] = 5.029353, states[40]= 0.005344
Saving checkpoint... 
Iteration: 1561071367, states[0] = -95.160302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579620013, states[0] = -60.231874, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1597950716, states[0] = -95.007887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616396761, states[0] = -95.343543, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1634974056, states[0] = -95.327589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653560881, states[0] = -95.316262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1672028915, states[0] = -73.789479, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1690599101, states[0] = -35.683609, states[40]= 0.000244
Saving checkpoint... 
Iteration: 1708981981, states[0] = -95.196190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727537359, states[0] = -88.975900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1746241341, states[0] = -95.295833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1764752874, states[0] = -95.073519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783149768, states[0] = -95.305356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1801595012, states[0] = -17.667043, states[40]= 0.001221
Saving checkpoint... 
Iteration: 1820249808, states[0] = -94.992633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838964276, states[0] = -95.092174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857688896, states[0] = -94.861958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1876117572, states[0] = -34.992275, states[40]= 0.000269
Saving checkpoint... 
Iteration: 1894671119, states[0] = -94.529514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913101935, states[0] = -20.017463, states[40]= 0.000975
Saving checkpoint... 
Iteration: 1931509021, states[0] = 23.317590, states[40]= 0.067207
Saving checkpoint... 
Iteration: 1949898443, states[0] = -95.056371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968633207, states[0] = -50.430065, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1987293988, states[0] = -95.001921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2005525135, states[0] = 20.143874, states[40]= 0.006931
Saving checkpoint... 
Iteration: 2023977911, states[0] = -95.072502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2042477406, states[0] = -95.072378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060863056, states[0] = -95.042879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073665534, states[0] = -92.990878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092123889, states[0] = -40.671745, states[40]= 0.000122
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.951109
 - CaMKt in component CaMK (millimolar): 0.007120
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.582035
 - nass in component intracellular_ions (millimolar): 6.582096
 - ki in component intracellular_ions (millimolar): 145.393500
 - kss in component intracellular_ions (millimolar): 145.393480
 - cansr in component intracellular_ions (millimolar): 1.320088
 - cajsr in component intracellular_ions (millimolar): 1.281777
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003601
 - hf in component INa (dimensionless): 0.880853
 - hs in component INa (dimensionless): 0.880848
 - j in component INa (dimensionless): 0.880819
 - hsp in component INa (dimensionless): 0.727438
 - jp in component INa (dimensionless): 0.880800
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710870
 - hLp in component INaL (dimensionless): 0.452459
 - a in component Ito (dimensionless): 0.000621
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.619836
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.694510
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934064
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001634
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332726
 - xs1 in component IKs (dimensionless): 0.244662
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997324
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:34:08 (7972): called boinc_finish(0)

</stderr_txt>
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