𝕏

Task 56016058

Name HuVeMOp_20240704040045698732_ORdGradInc_k_26-Pueyo_APDR-conf_281_0
Workunit 26602301
Created 4 Jul 2024, 2:00:50 UTC
Sent 4 Jul 2024, 2:45:45 UTC
Report deadline 7 Jul 2024, 12:21:45 UTC
Received 4 Jul 2024, 6:54:23 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224060
Run time 3 hours 2 min 38 sec
CPU time 58 min 1 sec
Validate state Valid
Credit 63.29
Device peak FLOPS 6.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.20 MB
Peak swap size 5.60 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704040045698732_ORdGradInc_k_26-Pueyo_APDR-conf_281.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704040045698732_ORdGradInc_k_26-Pueyo_APDR-conf_281_0_r1879093393_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704040045698732_ORdGradInc_k_26-Pueyo_APDR-conf_281_0_r1879093393_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.778766
     * GNaL_b in INaL: 0.005729
     * Gto_b in Ito: 0.087385
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031652
     * GKs_b in IKs: 0.001951
     * GK1_b in IK1: 0.167507
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 71.112738
     * GKb_b in IKb: 0.003801
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029368
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12021437, states[0] = 19.890454, states[40]= 0.008522
Saving checkpoint... 
Iteration: 24868213, states[0] = -95.057905, states[40]= 0.000000
Saving checkpoint... 
Iteration: 33408012, states[0] = -95.057495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 46150510, states[0] = -75.703066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58948134, states[0] = -95.044693, states[40]= 0.000000
Saving checkpoint... 
Iteration: 71740980, states[0] = -94.915914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84245715, states[0] = -94.918551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 96944382, states[0] = -95.031869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 109668385, states[0] = -94.226426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 118252094, states[0] = -94.921446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 130848154, states[0] = -94.997783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143593765, states[0] = -13.411922, states[40]= 0.001702
Saving checkpoint... 
Iteration: 156338743, states[0] = -94.991919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169137795, states[0] = -56.612290, states[40]= 0.000009
Saving checkpoint... 
Iteration: 181797825, states[0] = -94.964810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 194121309, states[0] = -39.283757, states[40]= 0.000146
Saving checkpoint... 
Iteration: 207001835, states[0] = 45.740104, states[40]= 0.083843
Saving checkpoint... 
Iteration: 219787810, states[0] = -94.956146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 232635329, states[0] = -53.846700, states[40]= 0.000015
Saving checkpoint... 
Iteration: 245332762, states[0] = -94.987704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258024491, states[0] = 20.032550, states[40]= 0.007082
Saving checkpoint... 
Iteration: 270536561, states[0] = 16.484441, states[40]= 0.005348
Saving checkpoint... 
Iteration: 283374319, states[0] = -95.006796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295809800, states[0] = -94.973207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308425643, states[0] = -95.022084, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320929011, states[0] = -95.022844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333200488, states[0] = -94.833997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345879001, states[0] = -95.008456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358447980, states[0] = -95.026737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370835901, states[0] = -94.989280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383214299, states[0] = -94.860446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396030961, states[0] = 18.274130, states[40]= 0.005830
Saving checkpoint... 
Iteration: 408569092, states[0] = 3.511053, states[40]= 0.004597
Saving checkpoint... 
Iteration: 421246392, states[0] = -94.910787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433989392, states[0] = -95.033178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 446511594, states[0] = 22.372769, states[40]= 0.036413
Saving checkpoint... 
Iteration: 459250565, states[0] = -94.916215, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471907775, states[0] = -95.017438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484297457, states[0] = -94.963853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 496859173, states[0] = -95.000507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 509574420, states[0] = 0.779606, states[40]= 0.004335
Saving checkpoint... 
Iteration: 522182980, states[0] = -94.791784, states[40]= 0.000000
Saving checkpoint... 
Iteration: 535081646, states[0] = -3.585494, states[40]= 0.003664
Saving checkpoint... 
Iteration: 547786953, states[0] = -94.955021, states[40]= 0.000000
Saving checkpoint... 
Iteration: 560326615, states[0] = -94.983876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 567480669, states[0] = -95.031922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 576226536, states[0] = -94.881361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 588963798, states[0] = -95.029361, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601839741, states[0] = -94.991168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 614727069, states[0] = -94.882199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 627686159, states[0] = -94.802025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640416228, states[0] = -95.019559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 653048203, states[0] = 12.289090, states[40]= 0.004956
Saving checkpoint... 
Iteration: 665582566, states[0] = -4.213991, states[40]= 0.003544
Saving checkpoint... 
Iteration: 678183230, states[0] = -94.792638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690571372, states[0] = 2.381234, states[40]= 0.004502
Saving checkpoint... 
Iteration: 703194845, states[0] = -94.822111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 715463748, states[0] = -95.029268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727688863, states[0] = -94.808847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740138798, states[0] = -57.680961, states[40]= 0.000008
Saving checkpoint... 
Iteration: 752911051, states[0] = -95.018135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765141356, states[0] = -60.605883, states[40]= 0.000005
Saving checkpoint... 
Iteration: 777612946, states[0] = -31.249674, states[40]= 0.000416
Saving checkpoint... 
Iteration: 790182239, states[0] = -94.788529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802780372, states[0] = -94.948845, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815386484, states[0] = -95.010734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828014543, states[0] = 21.894836, states[40]= 0.019766
Saving checkpoint... 
Iteration: 840544042, states[0] = 13.840298, states[40]= 0.005039
Saving checkpoint... 
Iteration: 853174365, states[0] = -94.689958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865770572, states[0] = -94.939083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 878426106, states[0] = -95.021796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890879566, states[0] = -95.008287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 903513004, states[0] = 22.126915, states[40]= 0.026764
Saving checkpoint... 
Iteration: 916063804, states[0] = 5.957130, states[40]= 0.004747
Saving checkpoint... 
Iteration: 928830452, states[0] = -94.985864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941511304, states[0] = 22.431774, states[40]= 0.038904
Saving checkpoint... 
Iteration: 954262261, states[0] = -94.929981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967006257, states[0] = 25.406381, states[40]= 0.124510
Saving checkpoint... 
Iteration: 979475270, states[0] = -95.030873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992112959, states[0] = -31.261806, states[40]= 0.000416
Saving checkpoint... 
Iteration: 1004922800, states[0] = -95.020932, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017455753, states[0] = -95.027708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1025928711, states[0] = -95.022293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1038445987, states[0] = -95.025895, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050995422, states[0] = -95.033513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1063785818, states[0] = -94.953664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1076372133, states[0] = -95.005407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1089094527, states[0] = -14.029683, states[40]= 0.001604
Saving checkpoint... 
Iteration: 1101791256, states[0] = -94.958359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114296241, states[0] = -94.962456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127105187, states[0] = -23.973852, states[40]= 0.000761
Saving checkpoint... 
Iteration: 1139716949, states[0] = -94.864686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152418240, states[0] = -95.019719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165016743, states[0] = 21.564224, states[40]= 0.013774
Saving checkpoint... 
Iteration: 1173558798, states[0] = 8.102724, states[40]= 0.004831
Saving checkpoint... 
Iteration: 1186097585, states[0] = -16.863067, states[40]= 0.001239
Saving checkpoint... 
Iteration: 1198925275, states[0] = -95.021386, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1211598350, states[0] = -17.577670, states[40]= 0.001166
Saving checkpoint... 
Iteration: 1224311539, states[0] = -94.973772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236785194, states[0] = -94.952989, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249370028, states[0] = -95.004474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261861802, states[0] = -95.001117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274765556, states[0] = -94.933441, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1287390435, states[0] = -95.011716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1300229321, states[0] = -94.885334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312968505, states[0] = -95.029624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325518141, states[0] = 21.336287, states[40]= 0.011465
Saving checkpoint... 
Iteration: 1338372526, states[0] = -95.005380, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1350938771, states[0] = -95.024246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363391397, states[0] = -95.011974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376048401, states[0] = 12.214292, states[40]= 0.004953
Saving checkpoint... 
Iteration: 1388711797, states[0] = -94.855172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401502206, states[0] = 42.708888, states[40]= 0.105150
Saving checkpoint... 
Iteration: 1409840019, states[0] = -94.990767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422426717, states[0] = -95.021570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1434669467, states[0] = -94.342090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447348356, states[0] = -94.994920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1459913538, states[0] = -95.018313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472692971, states[0] = -94.817588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1485120319, states[0] = -38.294218, states[40]= 0.000169
Saving checkpoint... 
Iteration: 1497836323, states[0] = -94.988745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1510289453, states[0] = -23.402359, states[40]= 0.000793
Saving checkpoint... 
Iteration: 1523037377, states[0] = -95.215562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1535464634, states[0] = -0.878236, states[40]= 0.004628
Saving checkpoint... 
Iteration: 1547952647, states[0] = -95.250988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1560433119, states[0] = -81.482924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1573329505, states[0] = -75.242562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585823879, states[0] = 19.410274, states[40]= 0.008474
Saving checkpoint... 
Iteration: 1598589234, states[0] = -95.167442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607225736, states[0] = -69.531143, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1619652539, states[0] = -95.264885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1632168946, states[0] = -95.121999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1644606952, states[0] = 25.684329, states[40]= 0.101329
Saving checkpoint... 
Iteration: 1657307418, states[0] = -46.080076, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1669950995, states[0] = -95.000603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682563654, states[0] = -95.108042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1695372867, states[0] = -8.542013, states[40]= 0.002983
Saving checkpoint... 
Iteration: 1707858750, states[0] = -95.272497, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720427212, states[0] = -95.235695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732826892, states[0] = 18.260563, states[40]= 0.007548
Saving checkpoint... 
Iteration: 1745578029, states[0] = -95.145366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1758046123, states[0] = 9.495585, states[40]= 0.005707
Saving checkpoint... 
Iteration: 1770653609, states[0] = 5.461838, states[40]= 0.005393
Saving checkpoint... 
Iteration: 1782950771, states[0] = 7.037794, states[40]= 0.005516
Saving checkpoint... 
Iteration: 1795453011, states[0] = -95.266717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808186201, states[0] = -94.844003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820689947, states[0] = -94.845468, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1833201968, states[0] = -94.861342, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845583887, states[0] = -5.887624, states[40]= 0.003218
Saving checkpoint... 
Iteration: 1856556329, states[0] = 8.868466, states[40]= 0.004862
Saving checkpoint... 
Iteration: 1866923946, states[0] = -95.029829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1879404504, states[0] = -95.021904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887895731, states[0] = -95.017882, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900374745, states[0] = -95.009208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913097719, states[0] = -17.122833, states[40]= 0.001212
Saving checkpoint... 
Iteration: 1925600588, states[0] = -19.766764, states[40]= 0.000988
Saving checkpoint... 
Iteration: 1938138530, states[0] = -57.469966, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1950886763, states[0] = -95.010768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1963510902, states[0] = 22.517159, states[40]= 0.042693
Saving checkpoint... 
Iteration: 1975865575, states[0] = -95.002510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988482634, states[0] = -95.031427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001109776, states[0] = -28.278423, states[40]= 0.000558
Saving checkpoint... 
Iteration: 2013573759, states[0] = 1.133862, states[40]= 0.004375
Saving checkpoint... 
Iteration: 2026133373, states[0] = -51.719601, states[40]= 0.000021
Saving checkpoint... 
Iteration: 2038771123, states[0] = -94.938859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051298587, states[0] = -94.963664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2063731236, states[0] = -94.887785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076111068, states[0] = -29.481982, states[40]= 0.000500
Saving checkpoint... 
Iteration: 2083869695, states[0] = -95.003735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090242398, states[0] = -94.904165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2097674728, states[0] = -94.699579, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909173
 - CaMKt in component CaMK (millimolar): 0.007100
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.572924
 - nass in component intracellular_ions (millimolar): 6.572985
 - ki in component intracellular_ions (millimolar): 145.402589
 - kss in component intracellular_ions (millimolar): 145.402570
 - cansr in component intracellular_ions (millimolar): 1.319724
 - cajsr in component intracellular_ions (millimolar): 1.281561
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880128
 - hs in component INa (dimensionless): 0.880123
 - j in component INa (dimensionless): 0.880094
 - hsp in component INa (dimensionless): 0.726070
 - jp in component INa (dimensionless): 0.880075
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709982
 - hLp in component INaL (dimensionless): 0.451852
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620677
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695576
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935484
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329346
 - xs1 in component IKs (dimensionless): 0.241894
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:53:26 (28864): called boinc_finish(0)

</stderr_txt>
]]>


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