𝕏

Task 56015543

Name HuVeMOp_20240704035045497193_ORdGradInc_k_26-Pueyo_APDR-conf_80_0
Workunit 26602050
Created 4 Jul 2024, 1:50:50 UTC
Sent 4 Jul 2024, 2:42:22 UTC
Report deadline 7 Jul 2024, 12:18:22 UTC
Received 4 Jul 2024, 6:00:02 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241714
Run time 1 hours 46 min 9 sec
CPU time 1 hours 45 min 39 sec
Validate state Valid
Credit 58.47
Device peak FLOPS 4.33 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.30 MB
Peak swap size 1.44 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704035045497193_ORdGradInc_k_26-Pueyo_APDR-conf_80.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704035045497193_ORdGradInc_k_26-Pueyo_APDR-conf_80_0_r10214518_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704035045497193_ORdGradInc_k_26-Pueyo_APDR-conf_80_0_r10214518_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.258338
     * GNaL_b in INaL: 0.006175
     * Gto_b in Ito: 0.084124
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031911
     * GKs_b in IKs: 0.001900
     * GK1_b in IK1: 0.161896
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.490098
     * GKb_b in IKb: 0.003802
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033749
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12904624, states[0] = -95.114067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 25721290, states[0] = -94.939102, states[40]= 0.000000
Saving checkpoint... 
Iteration: 38535125, states[0] = 16.826522, states[40]= 0.005563
Saving checkpoint... 
Iteration: 51284548, states[0] = -94.986949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 64240649, states[0] = -94.928628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76968209, states[0] = -95.051564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89702888, states[0] = -94.855121, states[40]= 0.000000
Saving checkpoint... 
Iteration: 102615494, states[0] = -33.649322, states[40]= 0.000311
Saving checkpoint... 
Iteration: 115441152, states[0] = -95.039172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128388667, states[0] = -95.024307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141299086, states[0] = -94.976578, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154069689, states[0] = 3.464983, states[40]= 0.004611
Saving checkpoint... 
Iteration: 166964906, states[0] = -95.040703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180190114, states[0] = -94.820805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192975049, states[0] = -95.041844, states[40]= 0.000000
Saving checkpoint... 
Iteration: 205625785, states[0] = -43.509806, states[40]= 0.000078
Saving checkpoint... 
Iteration: 218603911, states[0] = -22.393798, states[40]= 0.000833
Saving checkpoint... 
Iteration: 231618594, states[0] = -36.325410, states[40]= 0.000220
Saving checkpoint... 
Iteration: 244519072, states[0] = 21.596562, states[40]= 0.010718
Saving checkpoint... 
Iteration: 257234524, states[0] = -94.902973, states[40]= 0.000000
Saving checkpoint... 
Iteration: 269867851, states[0] = -95.014221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 282765162, states[0] = -94.942944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 295484915, states[0] = -95.042827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308129027, states[0] = -46.884197, states[40]= 0.000046
Saving checkpoint... 
Iteration: 320914746, states[0] = -95.029438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333794587, states[0] = -94.971168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 346740850, states[0] = -94.912171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359606151, states[0] = -24.490307, states[40]= 0.000734
Saving checkpoint... 
Iteration: 371519735, states[0] = 21.468948, states[40]= 0.010045
Saving checkpoint... 
Iteration: 380380548, states[0] = -95.018937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393049351, states[0] = 12.132359, states[40]= 0.005002
Saving checkpoint... 
Iteration: 405815639, states[0] = -94.986766, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418400272, states[0] = -95.025347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 430990825, states[0] = -95.043498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 443668641, states[0] = -94.118734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 456284632, states[0] = -94.962450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 468844135, states[0] = -95.003333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481546258, states[0] = 13.307757, states[40]= 0.005062
Saving checkpoint... 
Iteration: 494335535, states[0] = -94.998782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507025311, states[0] = 20.205683, states[40]= 0.007075
Saving checkpoint... 
Iteration: 519664205, states[0] = -92.359242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 532493964, states[0] = -95.043828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 545447508, states[0] = -95.036617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558412142, states[0] = -95.028597, states[40]= 0.000000
Saving checkpoint... 
Iteration: 571217897, states[0] = -94.875375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583967188, states[0] = -95.040032, states[40]= 0.000000
Saving checkpoint... 
Iteration: 597029104, states[0] = 19.169163, states[40]= 0.006256
Saving checkpoint... 
Iteration: 609966020, states[0] = -95.039828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 622896787, states[0] = -95.024167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 635496342, states[0] = -95.044054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648381915, states[0] = -95.019253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661187598, states[0] = -94.813673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673858549, states[0] = -95.010011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686453614, states[0] = -95.037664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699092739, states[0] = -11.977273, states[40]= 0.001947
Saving checkpoint... 
Iteration: 711801403, states[0] = -94.976357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 724656549, states[0] = -82.381926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737537414, states[0] = 16.512018, states[40]= 0.005410
Saving checkpoint... 
Iteration: 750534109, states[0] = 17.621970, states[40]= 0.005656
Saving checkpoint... 
Iteration: 763454519, states[0] = -95.037779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 776324486, states[0] = -94.992193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 789288239, states[0] = -94.965471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802202811, states[0] = -94.846776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 815000772, states[0] = 44.814582, states[40]= 0.011120
Saving checkpoint... 
Iteration: 827915602, states[0] = -95.029334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840896975, states[0] = -95.024088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853961955, states[0] = -95.039010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867005324, states[0] = 27.871185, states[40]= 0.141213
Saving checkpoint... 
Iteration: 879946473, states[0] = -95.036209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892796553, states[0] = -94.972417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 905773552, states[0] = -94.951472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 918789838, states[0] = -94.966785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931770606, states[0] = -94.948401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944783931, states[0] = -94.961502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 957891845, states[0] = -95.022405, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970993350, states[0] = -95.043478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 984033204, states[0] = 17.914793, states[40]= 0.005740
Saving checkpoint... 
Iteration: 996947613, states[0] = -95.036355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1009892290, states[0] = -95.022515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022937768, states[0] = -95.034368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035833126, states[0] = -94.997103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1048826167, states[0] = -94.993043, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061981155, states[0] = -95.041815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075139532, states[0] = -58.432337, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1088412525, states[0] = -95.028367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1101684034, states[0] = -94.802176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114818911, states[0] = -94.988472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127896538, states[0] = -95.023775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1141112425, states[0] = -30.410423, states[40]= 0.000452
Saving checkpoint... 
Iteration: 1154468348, states[0] = -95.039859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167674240, states[0] = -94.670411, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180826466, states[0] = -94.993140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193908718, states[0] = -95.027274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207131573, states[0] = -49.609449, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1220403274, states[0] = -95.025725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1233299386, states[0] = -94.974461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1246154549, states[0] = -78.919986, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1259352262, states[0] = -95.006791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272654924, states[0] = -79.562838, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285759546, states[0] = -94.935855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298970383, states[0] = -95.040086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312419789, states[0] = -95.030088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325775216, states[0] = -94.952893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339077493, states[0] = -0.655982, states[40]= 0.004156
Saving checkpoint... 
Iteration: 1352428967, states[0] = -95.032241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1365962153, states[0] = -95.038723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1379481972, states[0] = -95.041731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392834106, states[0] = -94.997428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1406081165, states[0] = -2.926712, states[40]= 0.003789
Saving checkpoint... 
Iteration: 1419572347, states[0] = 2.162968, states[40]= 0.004494
Saving checkpoint... 
Iteration: 1432804473, states[0] = -94.978233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1446008587, states[0] = 23.958085, states[40]= 0.073808
Saving checkpoint... 
Iteration: 1459488691, states[0] = -95.042581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472792033, states[0] = -94.968315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486353804, states[0] = -95.007365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499676118, states[0] = -94.725802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1512998990, states[0] = -33.401933, states[40]= 0.000312
Saving checkpoint... 
Iteration: 1526346984, states[0] = -95.248958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539593802, states[0] = -95.301140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552796607, states[0] = -95.310387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1566196614, states[0] = -95.196219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1579747790, states[0] = -95.276355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1593287157, states[0] = -95.314147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607086149, states[0] = -95.314781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620479585, states[0] = -95.167356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633978039, states[0] = -95.164269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647616675, states[0] = 21.989257, states[40]= 0.015937
Saving checkpoint... 
Iteration: 1661110828, states[0] = 23.743774, states[40]= 0.044708
Saving checkpoint... 
Iteration: 1674474898, states[0] = -95.157400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688091147, states[0] = -95.320556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1701712347, states[0] = -51.715856, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1715321898, states[0] = -95.248738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728834554, states[0] = -95.266282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742304328, states[0] = -95.219939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755808477, states[0] = -95.227259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769546588, states[0] = -94.686519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1783285915, states[0] = -21.939919, states[40]= 0.000899
Saving checkpoint... 
Iteration: 1796909860, states[0] = -95.229606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810529093, states[0] = 18.597954, states[40]= 0.006120
Saving checkpoint... 
Iteration: 1824245749, states[0] = -94.952926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838129591, states[0] = -49.170398, states[40]= 0.000032
Saving checkpoint... 
Iteration: 1851878491, states[0] = -95.032797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1865517031, states[0] = 21.879622, states[40]= 0.013615
Saving checkpoint... 
Iteration: 1879338164, states[0] = -95.006211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1893589923, states[0] = -9.735299, states[40]= 0.002388
Saving checkpoint... 
Iteration: 1907159538, states[0] = -87.639588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920871687, states[0] = -95.016645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934661112, states[0] = -89.575892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1948258647, states[0] = -94.935242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1961940676, states[0] = -95.034935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1975519066, states[0] = 21.595099, states[40]= 0.010723
Saving checkpoint... 
Iteration: 1989318315, states[0] = -94.987756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003065671, states[0] = 5.379516, states[40]= 0.004741
Saving checkpoint... 
Iteration: 2016552280, states[0] = 10.994109, states[40]= 0.004959
Saving checkpoint... 
Iteration: 2030293556, states[0] = -94.969272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2044082383, states[0] = -3.740739, states[40]= 0.003638
Saving checkpoint... 
Iteration: 2057643407, states[0] = -62.980520, states[40]= 0.000003
Saving checkpoint... 
Iteration: 2071326645, states[0] = -94.992660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084931037, states[0] = -95.032211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2099156819, states[0] = -82.847686, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.919405
 - CaMKt in component CaMK (millimolar): 0.006968
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.569994
 - nass in component intracellular_ions (millimolar): 6.570054
 - ki in component intracellular_ions (millimolar): 145.407991
 - kss in component intracellular_ions (millimolar): 145.407971
 - cansr in component intracellular_ions (millimolar): 1.310697
 - cajsr in component intracellular_ions (millimolar): 1.272634
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880305
 - hs in component INa (dimensionless): 0.880300
 - j in component INa (dimensionless): 0.880271
 - hsp in component INa (dimensionless): 0.726404
 - jp in component INa (dimensionless): 0.880252
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710182
 - hLp in component INaL (dimensionless): 0.451928
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620447
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695093
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934307
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999882
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001598
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334124
 - xs1 in component IKs (dimensionless): 0.243421
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997333
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:41:49 (11752): called boinc_finish(0)

</stderr_txt>
]]>