𝕏

Task 56012260

Name HuVeMOp_20240704030042216496_ORdGradInc_k_26-Pueyo_APDR-conf_777_0
Workunit 26600474
Created 4 Jul 2024, 1:00:53 UTC
Sent 4 Jul 2024, 2:17:35 UTC
Report deadline 7 Jul 2024, 11:53:35 UTC
Received 5 Jul 2024, 2:31:28 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 230332
Run time 2 hours 14 min 44 sec
CPU time 2 hours 12 min 57 sec
Validate state Valid
Credit 61.57
Device peak FLOPS 3.58 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 6.91 MB
Peak swap size 1.43 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704030042216496_ORdGradInc_k_26-Pueyo_APDR-conf_777.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704030042216496_ORdGradInc_k_26-Pueyo_APDR-conf_777_0_r1084938885_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704030042216496_ORdGradInc_k_26-Pueyo_APDR-conf_777_0_r1084938885_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.782453
     * GNaL_b in INaL: 0.006229
     * Gto_b in Ito: 0.087916
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031359
     * GKs_b in IKs: 0.001901
     * GK1_b in IK1: 0.165624
     * Gncx_b in INaCa_i: 0.000964
     * Pnak_b in INaK: 69.283214
     * GKb_b in IKb: 0.003772
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030046
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 17502591, states[0] = 39.415788, states[40]= 0.125250
Saving checkpoint... 
Iteration: 34995582, states[0] = -95.061007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52473184, states[0] = -95.043923, states[40]= 0.000000
Saving checkpoint... 
Iteration: 69907689, states[0] = -95.022322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 87384898, states[0] = -95.010593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104846731, states[0] = -94.991920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122305990, states[0] = -94.965356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139793098, states[0] = -94.954139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157283740, states[0] = -94.945237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174762801, states[0] = -94.923158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 192246985, states[0] = -94.903156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209735193, states[0] = -94.886071, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227164097, states[0] = -90.283687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 244667398, states[0] = -92.934401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262031106, states[0] = 18.579197, states[40]= 0.005787
Saving checkpoint... 
Iteration: 279474138, states[0] = -95.024727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296990614, states[0] = -95.027005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314476268, states[0] = -95.025005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331937080, states[0] = -95.017992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 349272051, states[0] = -94.932685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366721343, states[0] = -94.863232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384273419, states[0] = -94.934083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401697364, states[0] = -94.817353, states[40]= 0.000000
Saving checkpoint... 
Iteration: 419174760, states[0] = -94.582029, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435317470, states[0] = -94.970775, states[40]= 0.000000
Saving checkpoint... 
Iteration: 452180143, states[0] = -94.747462, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469482768, states[0] = -95.025823, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486922846, states[0] = -95.014637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504390021, states[0] = -95.005282, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521899105, states[0] = -95.008148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539376016, states[0] = -95.000310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 556786181, states[0] = -94.946333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574235853, states[0] = -94.886633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591731434, states[0] = -94.879790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609207223, states[0] = -94.837077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626644830, states[0] = -61.785448, states[40]= 0.000004
Saving checkpoint... 
Iteration: 643980274, states[0] = -95.025354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661487912, states[0] = -95.026390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 678948523, states[0] = -95.020065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 696284325, states[0] = -94.944537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 713793033, states[0] = -94.952234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 731314244, states[0] = -94.968399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 748812689, states[0] = -94.967314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766276580, states[0] = -94.937036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783643567, states[0] = -60.310939, states[40]= 0.000005
Saving checkpoint... 
Iteration: 801155482, states[0] = -76.455728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818624878, states[0] = -40.442202, states[40]= 0.000128
Saving checkpoint... 
Iteration: 836076162, states[0] = 0.710510, states[40]= 0.004315
Saving checkpoint... 
Iteration: 853570688, states[0] = 3.498465, states[40]= 0.004585
Saving checkpoint... 
Iteration: 871058959, states[0] = 8.641268, states[40]= 0.004835
Saving checkpoint... 
Iteration: 888548909, states[0] = 12.529228, states[40]= 0.004936
Saving checkpoint... 
Iteration: 906039137, states[0] = 16.023578, states[40]= 0.005191
Saving checkpoint... 
Iteration: 923535860, states[0] = 17.112342, states[40]= 0.005371
Saving checkpoint... 
Iteration: 940935135, states[0] = -95.017154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958400103, states[0] = -95.008153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975885853, states[0] = -95.003556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993331556, states[0] = -94.979119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1010801411, states[0] = -94.958834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027932041, states[0] = -95.016414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045435039, states[0] = -95.017062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1062955482, states[0] = -95.021095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080366359, states[0] = -94.996129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097876612, states[0] = -95.000154, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1115418885, states[0] = -95.013228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1132843828, states[0] = -94.985705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150359359, states[0] = -94.993090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167788307, states[0] = -94.947825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1185179189, states[0] = -94.732880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202637847, states[0] = -53.915421, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1220112965, states[0] = -29.200694, states[40]= 0.000530
Saving checkpoint... 
Iteration: 1237629664, states[0] = -45.241888, states[40]= 0.000062
Saving checkpoint... 
Iteration: 1255064109, states[0] = 6.489299, states[40]= 0.004761
Saving checkpoint... 
Iteration: 1272534623, states[0] = 17.508355, states[40]= 0.005458
Saving checkpoint... 
Iteration: 1290008388, states[0] = 23.549927, states[40]= 0.077990
Saving checkpoint... 
Iteration: 1307532214, states[0] = 18.251690, states[40]= 0.005668
Saving checkpoint... 
Iteration: 1325026879, states[0] = 19.739635, states[40]= 0.006439
Saving checkpoint... 
Iteration: 1342539027, states[0] = 16.061059, states[40]= 0.005196
Saving checkpoint... 
Iteration: 1360048594, states[0] = 12.646201, states[40]= 0.004940
Saving checkpoint... 
Iteration: 1377586204, states[0] = -5.581734, states[40]= 0.003256
Saving checkpoint... 
Iteration: 1394988055, states[0] = -95.025910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412407095, states[0] = -95.009880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429867434, states[0] = -94.996333, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447291913, states[0] = -94.950779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1464758651, states[0] = -94.916864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482236269, states[0] = -94.886639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1499748246, states[0] = -94.903641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517184894, states[0] = -17.425181, states[40]= 0.001301
Saving checkpoint... 
Iteration: 1534619929, states[0] = -57.219700, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1552014461, states[0] = -51.282513, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1569417314, states[0] = -55.170689, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1586805960, states[0] = -41.988766, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1604199923, states[0] = -35.483358, states[40]= 0.000254
Saving checkpoint... 
Iteration: 1621334986, states[0] = -82.188695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638661399, states[0] = 1.457070, states[40]= 0.004990
Saving checkpoint... 
Iteration: 1656055808, states[0] = 4.812169, states[40]= 0.005336
Saving checkpoint... 
Iteration: 1673410140, states[0] = 23.612917, states[40]= 0.051717
Saving checkpoint... 
Iteration: 1690801786, states[0] = 46.796111, states[40]= 0.065329
Saving checkpoint... 
Iteration: 1708247637, states[0] = 9.201349, states[40]= 0.005664
Saving checkpoint... 
Iteration: 1725667128, states[0] = -2.534866, states[40]= 0.004350
Saving checkpoint... 
Iteration: 1743064908, states[0] = -0.915434, states[40]= 0.004644
Saving checkpoint... 
Iteration: 1760476061, states[0] = -10.382369, states[40]= 0.002551
Saving checkpoint... 
Iteration: 1777881275, states[0] = -15.770763, states[40]= 0.001535
Saving checkpoint... 
Iteration: 1795270826, states[0] = -5.516846, states[40]= 0.003705
Saving checkpoint... 
Iteration: 1812666302, states[0] = -93.944877, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1830052863, states[0] = 10.522498, states[40]= 0.004904
Saving checkpoint... 
Iteration: 1847327465, states[0] = -94.993283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1864654647, states[0] = -76.381652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1882039947, states[0] = 15.656419, states[40]= 0.005156
Saving checkpoint... 
Iteration: 1899451668, states[0] = -95.023439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916818706, states[0] = -94.972736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934186560, states[0] = -94.790890, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1951569149, states[0] = 4.208586, states[40]= 0.004637
Saving checkpoint... 
Iteration: 1968876843, states[0] = -95.000065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1986334820, states[0] = -94.980523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003733886, states[0] = -94.882763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021100919, states[0] = -18.145932, states[40]= 0.001117
Saving checkpoint... 
Iteration: 2038529320, states[0] = 19.088188, states[40]= 0.006017
Saving checkpoint... 
Iteration: 2055912504, states[0] = -95.010903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073219398, states[0] = -94.858619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090650520, states[0] = -68.972252, states[40]= 0.000001
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.902747
 - CaMKt in component CaMK (millimolar): 0.007180
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.623294
 - nass in component intracellular_ions (millimolar): 6.623354
 - ki in component intracellular_ions (millimolar): 145.351485
 - kss in component intracellular_ions (millimolar): 145.351465
 - cansr in component intracellular_ions (millimolar): 1.322979
 - cajsr in component intracellular_ions (millimolar): 1.284528
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003618
 - hf in component INa (dimensionless): 0.880016
 - hs in component INa (dimensionless): 0.880012
 - j in component INa (dimensionless): 0.879982
 - hsp in component INa (dimensionless): 0.725859
 - jp in component INa (dimensionless): 0.879963
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709194
 - hLp in component INaL (dimensionless): 0.449830
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.618005
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.692312
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933449
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999976
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001643
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333982
 - xs1 in component IKs (dimensionless): 0.246308
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997337
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:31:07 (6600): called boinc_finish(0)

</stderr_txt>
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