𝕏

Task 56010385

Name HuVeMOp_20240704024040640595_ORdGradInc_k_26-Pueyo_APDR-conf_860_1
Workunit 26599567
Created 4 Jul 2024, 0:40:44 UTC
Sent 4 Jul 2024, 2:01:44 UTC
Report deadline 7 Jul 2024, 11:37:44 UTC
Received 4 Jul 2024, 5:34:26 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 224060
Run time 3 hours 1 min 41 sec
CPU time 57 min 52 sec
Validate state Valid
Credit 62.93
Device peak FLOPS 6.18 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.17 MB
Peak swap size 5.55 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704024040640595_ORdGradInc_k_26-Pueyo_APDR-conf_860.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704024040640595_ORdGradInc_k_26-Pueyo_APDR-conf_860_1_r837123822_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704024040640595_ORdGradInc_k_26-Pueyo_APDR-conf_860_1_r837123822_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.077812
     * GNaL_b in INaL: 0.006042
     * Gto_b in Ito: 0.086562
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032328
     * GKs_b in IKs: 0.001961
     * GK1_b in IK1: 0.159376
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 70.282729
     * GKb_b in IKb: 0.003774
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035740
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12156455, states[0] = -91.193321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 24515256, states[0] = 21.518308, states[40]= 0.017464
Saving checkpoint... 
Iteration: 37380564, states[0] = -95.014141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 48685968, states[0] = -94.792711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61346228, states[0] = -94.980480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 74030165, states[0] = 18.471481, states[40]= 0.005982
Saving checkpoint... 
Iteration: 86698456, states[0] = -94.803189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 99428830, states[0] = -94.997264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 112140960, states[0] = -61.451281, states[40]= 0.000004
Saving checkpoint... 
Iteration: 124966778, states[0] = -95.001623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 137459590, states[0] = -94.999622, states[40]= 0.000000
Saving checkpoint... 
Iteration: 150088055, states[0] = -8.627527, states[40]= 0.002616
Saving checkpoint... 
Iteration: 162694743, states[0] = -94.787904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 175176496, states[0] = -94.697483, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187515492, states[0] = 21.889478, states[40]= 0.016945
Saving checkpoint... 
Iteration: 200172078, states[0] = -94.539374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213049038, states[0] = 12.009283, states[40]= 0.004960
Saving checkpoint... 
Iteration: 225755245, states[0] = -94.889196, states[40]= 0.000000
Saving checkpoint... 
Iteration: 238435909, states[0] = -94.993304, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250736400, states[0] = -94.863216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263203602, states[0] = -94.805418, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271889974, states[0] = -94.980929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 284191291, states[0] = -94.779316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296982370, states[0] = -95.001253, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309312685, states[0] = -94.943159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 322203264, states[0] = -94.804662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335120779, states[0] = -39.412137, states[40]= 0.000141
Saving checkpoint... 
Iteration: 347965038, states[0] = -94.998604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 360455369, states[0] = -94.996945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 372896949, states[0] = -94.983055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385299152, states[0] = -94.933027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 398126462, states[0] = -45.212969, states[40]= 0.000059
Saving checkpoint... 
Iteration: 410886466, states[0] = -94.979630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423325391, states[0] = -94.951371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 435928252, states[0] = -94.991384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448606643, states[0] = -25.790382, states[40]= 0.000666
Saving checkpoint... 
Iteration: 461384736, states[0] = -94.979002, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474109783, states[0] = -28.773008, states[40]= 0.000525
Saving checkpoint... 
Iteration: 486701419, states[0] = -94.800806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498917996, states[0] = -94.988865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 507657052, states[0] = -84.392828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520521035, states[0] = 20.917537, states[40]= 0.008814
Saving checkpoint... 
Iteration: 529263986, states[0] = -94.899283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 541688138, states[0] = -94.771487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554032171, states[0] = 17.995000, states[40]= 0.005754
Saving checkpoint... 
Iteration: 566710771, states[0] = -94.819210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579529978, states[0] = 18.660565, states[40]= 0.006018
Saving checkpoint... 
Iteration: 592313606, states[0] = -94.943601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604923561, states[0] = -94.990170, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613217555, states[0] = -94.831753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 626010914, states[0] = 22.680451, states[40]= 0.042747
Saving checkpoint... 
Iteration: 638694218, states[0] = -94.785585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 651130786, states[0] = -49.814033, states[40]= 0.000029
Saving checkpoint... 
Iteration: 663673630, states[0] = -94.616658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676692070, states[0] = -94.780807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689424914, states[0] = -94.990439, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702039179, states[0] = 15.657006, states[40]= 0.005242
Saving checkpoint... 
Iteration: 714460975, states[0] = -94.997688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 727107948, states[0] = -27.028560, states[40]= 0.000608
Saving checkpoint... 
Iteration: 739794811, states[0] = -94.929263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 752563767, states[0] = 5.960965, states[40]= 0.004750
Saving checkpoint... 
Iteration: 765223367, states[0] = -94.841856, states[40]= 0.000000
Saving checkpoint... 
Iteration: 777986066, states[0] = -95.001426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 790515595, states[0] = 21.876907, states[40]= 0.016662
Saving checkpoint... 
Iteration: 803239569, states[0] = -94.867495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 816051396, states[0] = 11.099264, states[40]= 0.004927
Saving checkpoint... 
Iteration: 828518499, states[0] = 21.401408, states[40]= 0.011171
Saving checkpoint... 
Iteration: 841153291, states[0] = -78.044947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 853898544, states[0] = -94.983230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 866766654, states[0] = -94.902062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879169966, states[0] = -94.352104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 891785697, states[0] = -94.921224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 904509770, states[0] = 23.005038, states[40]= 0.055863
Saving checkpoint... 
Iteration: 917145561, states[0] = -66.760220, states[40]= 0.000002
Saving checkpoint... 
Iteration: 929673340, states[0] = -94.604246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942200971, states[0] = -94.799592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 955215709, states[0] = -94.828178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 967824980, states[0] = -94.950765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980794728, states[0] = -94.929037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993727231, states[0] = -94.848195, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1006565025, states[0] = 5.393360, states[40]= 0.004721
Saving checkpoint... 
Iteration: 1019144689, states[0] = -65.653323, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1031898527, states[0] = -94.983109, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1044521912, states[0] = 20.733522, states[40]= 0.008279
Saving checkpoint... 
Iteration: 1057280335, states[0] = -94.916088, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064091582, states[0] = -11.630304, states[40]= 0.002010
Saving checkpoint... 
Iteration: 1072415626, states[0] = -94.987886, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1084997352, states[0] = -95.002653, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1097717550, states[0] = -94.831427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110520267, states[0] = 21.071734, states[40]= 0.009380
Saving checkpoint... 
Iteration: 1123101028, states[0] = -20.467028, states[40]= 0.000934
Saving checkpoint... 
Iteration: 1135788923, states[0] = -94.923960, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148512094, states[0] = 22.434268, states[40]= 0.032776
Saving checkpoint... 
Iteration: 1161088968, states[0] = -9.340665, states[40]= 0.002465
Saving checkpoint... 
Iteration: 1173406751, states[0] = -94.985424, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186024522, states[0] = 20.135010, states[40]= 0.007173
Saving checkpoint... 
Iteration: 1198603698, states[0] = -22.998632, states[40]= 0.000797
Saving checkpoint... 
Iteration: 1210884624, states[0] = -94.978477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1223222892, states[0] = -94.840742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236061785, states[0] = 6.834666, states[40]= 0.004790
Saving checkpoint... 
Iteration: 1248769104, states[0] = -94.904495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1261649919, states[0] = -72.749776, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1274254050, states[0] = -94.886878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1286883177, states[0] = -94.977922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1299496783, states[0] = -95.002445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1312194160, states[0] = -94.785017, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1324708687, states[0] = -94.814711, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337221739, states[0] = -94.838678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349812710, states[0] = -94.942488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1362702047, states[0] = -94.801511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1375228269, states[0] = -94.849649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387806488, states[0] = -94.938003, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400287251, states[0] = -94.922299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1412774821, states[0] = -94.910391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1425465718, states[0] = -94.998012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438303204, states[0] = -94.935501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451157955, states[0] = -85.850692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1463943505, states[0] = -94.993987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1476608292, states[0] = -27.354835, states[40]= 0.000593
Saving checkpoint... 
Iteration: 1489321073, states[0] = -94.947974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1502185181, states[0] = -18.209681, states[40]= 0.001170
Saving checkpoint... 
Iteration: 1515110048, states[0] = -47.051397, states[40]= 0.000045
Saving checkpoint... 
Iteration: 1523471003, states[0] = -5.643107, states[40]= 0.003645
Saving checkpoint... 
Iteration: 1536115620, states[0] = -55.253876, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1549026413, states[0] = -70.286356, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1561533606, states[0] = 15.664511, states[40]= 0.006558
Saving checkpoint... 
Iteration: 1574137906, states[0] = 13.653417, states[40]= 0.006177
Saving checkpoint... 
Iteration: 1586894529, states[0] = -95.160730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599542048, states[0] = -95.237632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1612007185, states[0] = -46.432316, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1624807019, states[0] = 25.793796, states[40]= 0.099099
Saving checkpoint... 
Iteration: 1637564839, states[0] = -95.093396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650420629, states[0] = -63.320429, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1663121443, states[0] = -95.212572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1671620644, states[0] = 20.516732, states[40]= 0.010406
Saving checkpoint... 
Iteration: 1684065381, states[0] = -95.095718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696624328, states[0] = -68.525502, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1709302435, states[0] = -95.180852, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1721796046, states[0] = -33.871865, states[40]= 0.000297
Saving checkpoint... 
Iteration: 1734379361, states[0] = -15.578958, states[40]= 0.001563
Saving checkpoint... 
Iteration: 1746829777, states[0] = -95.224904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1759447701, states[0] = -95.247271, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771899644, states[0] = -37.860411, states[40]= 0.000177
Saving checkpoint... 
Iteration: 1784706865, states[0] = 25.967643, states[40]= 0.101993
Saving checkpoint... 
Iteration: 1797344453, states[0] = 10.342862, states[40]= 0.005795
Saving checkpoint... 
Iteration: 1810356441, states[0] = -95.018206, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822810880, states[0] = -94.978315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835219951, states[0] = -94.861834, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1847964611, states[0] = -95.015537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1860720667, states[0] = -94.849042, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873263092, states[0] = -94.905957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885651364, states[0] = -75.588621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1898126689, states[0] = -45.719153, states[40]= 0.000055
Saving checkpoint... 
Iteration: 1906444225, states[0] = -94.996965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1919128372, states[0] = -47.374476, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1931274504, states[0] = -94.911220, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943982784, states[0] = -95.001218, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956576859, states[0] = -0.696336, states[40]= 0.004142
Saving checkpoint... 
Iteration: 1969305964, states[0] = -94.937680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981643296, states[0] = -63.960338, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1994433940, states[0] = -94.991827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006889097, states[0] = -94.979585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2019518720, states[0] = 21.361325, states[40]= 0.010900
Saving checkpoint... 
Iteration: 2032417898, states[0] = -94.987865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045341919, states[0] = -94.959664, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058064595, states[0] = 5.588126, states[40]= 0.004731
Saving checkpoint... 
Iteration: 2070835678, states[0] = -94.956264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083179623, states[0] = -94.733680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2095647443, states[0] = -69.242676, states[40]= 0.000001
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.878136
 - CaMKt in component CaMK (millimolar): 0.007002
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.591302
 - nass in component intracellular_ions (millimolar): 6.591362
 - ki in component intracellular_ions (millimolar): 145.385927
 - kss in component intracellular_ions (millimolar): 145.385907
 - cansr in component intracellular_ions (millimolar): 1.313028
 - cajsr in component intracellular_ions (millimolar): 1.275019
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003627
 - hf in component INa (dimensionless): 0.879589
 - hs in component INa (dimensionless): 0.879584
 - j in component INa (dimensionless): 0.879555
 - hsp in component INa (dimensionless): 0.725054
 - jp in component INa (dimensionless): 0.879535
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709275
 - hLp in component INaL (dimensionless): 0.451229
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621141
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695966
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935467
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001605
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330733
 - xs1 in component IKs (dimensionless): 0.241461
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997343
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
07:07:28 (7116): called boinc_finish(0)

</stderr_txt>
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