𝕏

Task 56010255

Name HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_725_2
Workunit 26331125
Created 4 Jul 2024, 0:33:41 UTC
Sent 4 Jul 2024, 2:10:45 UTC
Report deadline 7 Jul 2024, 11:46:45 UTC
Received 5 Jul 2024, 8:24:04 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 218836
Run time 1 hours 43 min 49 sec
CPU time 58 min 46 sec
Validate state Valid
Credit 62.63
Device peak FLOPS 5.93 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.29 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_725.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_725_2_r193785496_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630154541927258_ORdGradInc_k_25-Pueyo_APDR-conf_725_2_r193785496_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 118.713696
     * GNaL_b in INaL: 0.007022
     * Gto_b in Ito: 0.071210
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032677
     * GKs_b in IKs: 0.001948
     * GK1_b in IK1: 0.179855
     * Gncx_b in INaCa_i: 0.000976
     * Pnak_b in INaK: 69.777246
     * GKb_b in IKb: 0.003756
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.025717
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14196344, states[0] = -95.091611, states[40]= 0.000000
Saving checkpoint... 
Iteration: 27282061, states[0] = -95.169729, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40690943, states[0] = -95.035182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54204858, states[0] = -95.050608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 67641780, states[0] = -66.633466, states[40]= 0.000002
Saving checkpoint... 
Iteration: 80953291, states[0] = -95.202243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 94116822, states[0] = -36.393569, states[40]= 0.000214
Saving checkpoint... 
Iteration: 107394283, states[0] = -95.185141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 120808882, states[0] = -95.147692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134009885, states[0] = 25.703831, states[40]= 0.055659
Saving checkpoint... 
Iteration: 147461070, states[0] = -95.196365, states[40]= 0.000000
Saving checkpoint... 
Iteration: 160829645, states[0] = -95.157562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 174174645, states[0] = -94.965641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 187543939, states[0] = 14.671969, states[40]= 0.005483
Saving checkpoint... 
Iteration: 200641680, states[0] = -64.933246, states[40]= 0.000002
Saving checkpoint... 
Iteration: 214273927, states[0] = -95.119305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 227571377, states[0] = 2.627277, states[40]= 0.004661
Saving checkpoint... 
Iteration: 240976505, states[0] = -95.197387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254436832, states[0] = -95.191094, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267903209, states[0] = -95.183675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 281283037, states[0] = -95.126776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294540266, states[0] = 16.103881, states[40]= 0.005679
Saving checkpoint... 
Iteration: 307751706, states[0] = -95.097191, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321209125, states[0] = -95.038831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 334442368, states[0] = -95.192023, states[40]= 0.000000
Saving checkpoint... 
Iteration: 343829309, states[0] = -95.156500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357271170, states[0] = -95.116609, states[40]= 0.000000
Saving checkpoint... 
Iteration: 370671013, states[0] = -94.931796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384113439, states[0] = -32.542641, states[40]= 0.000350
Saving checkpoint... 
Iteration: 397553422, states[0] = 10.841736, states[40]= 0.005193
Saving checkpoint... 
Iteration: 410702652, states[0] = -95.027731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 423918988, states[0] = -95.187317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437310830, states[0] = -95.146149, states[40]= 0.000000
Saving checkpoint... 
Iteration: 449675007, states[0] = -94.966690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 462866791, states[0] = -95.172496, states[40]= 0.000000
Saving checkpoint... 
Iteration: 476216237, states[0] = -95.050211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489415612, states[0] = -95.186526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 498520634, states[0] = 22.572058, states[40]= 0.010601
Saving checkpoint... 
Iteration: 511955933, states[0] = -95.194214, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525286808, states[0] = -95.129601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538459201, states[0] = -95.194710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 551888393, states[0] = -95.179448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 565387775, states[0] = -95.179260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578711161, states[0] = -95.042052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 591950755, states[0] = -95.193337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 604993992, states[0] = -95.199246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618403780, states[0] = -95.183614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631782807, states[0] = -95.126396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 645014433, states[0] = 24.140642, states[40]= 0.022770
Saving checkpoint... 
Iteration: 658428425, states[0] = -95.189203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 671781494, states[0] = -95.125315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 685244211, states[0] = -95.088419, states[40]= 0.000000
Saving checkpoint... 
Iteration: 698385933, states[0] = -95.178649, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711816257, states[0] = -95.149235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 725070514, states[0] = 3.076715, states[40]= 0.004704
Saving checkpoint... 
Iteration: 738236110, states[0] = -95.078362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751591483, states[0] = -11.345161, states[40]= 0.002103
Saving checkpoint... 
Iteration: 764967907, states[0] = -95.195883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 778354843, states[0] = -95.167826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791698036, states[0] = -95.019322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 805456659, states[0] = -95.194186, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819258664, states[0] = -95.104329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832417497, states[0] = -95.186786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846184459, states[0] = -94.993440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860052079, states[0] = 11.398475, states[40]= 0.005223
Saving checkpoint... 
Iteration: 873419130, states[0] = -95.187130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886955229, states[0] = -95.193920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898440921, states[0] = -95.191484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 911671630, states[0] = -94.939744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 925095830, states[0] = -15.408094, states[40]= 0.001433
Saving checkpoint... 
Iteration: 938324450, states[0] = -95.153675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 951552189, states[0] = 11.353080, states[40]= 0.005221
Saving checkpoint... 
Iteration: 964951892, states[0] = -95.193344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978352787, states[0] = -95.166900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 991538136, states[0] = 16.909529, states[40]= 0.005829
Saving checkpoint... 
Iteration: 1004752266, states[0] = -95.097455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018417351, states[0] = -95.186663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031911532, states[0] = -95.185315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045442252, states[0] = -95.191652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058851881, states[0] = -95.166490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072504601, states[0] = 33.232904, states[40]= 0.130153
Saving checkpoint... 
Iteration: 1086031398, states[0] = 19.321674, states[40]= 0.006580
Saving checkpoint... 
Iteration: 1099733399, states[0] = -95.074643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113043493, states[0] = 14.854643, states[40]= 0.005503
Saving checkpoint... 
Iteration: 1126410797, states[0] = -95.185095, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1140108673, states[0] = -27.855498, states[40]= 0.000566
Saving checkpoint... 
Iteration: 1153890026, states[0] = -95.179630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1167222523, states[0] = -95.059408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180689669, states[0] = -95.003546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1190058131, states[0] = 8.846119, states[40]= 0.005092
Saving checkpoint... 
Iteration: 1203276986, states[0] = -95.121300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216540526, states[0] = 16.004896, states[40]= 0.005662
Saving checkpoint... 
Iteration: 1230078653, states[0] = -1.500609, states[40]= 0.004118
Saving checkpoint... 
Iteration: 1243369870, states[0] = -95.173202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1256508605, states[0] = 26.512274, states[40]= 0.072889
Saving checkpoint... 
Iteration: 1269670169, states[0] = -94.917246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1282833638, states[0] = -95.158200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296136804, states[0] = -58.462101, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1309276130, states[0] = -95.120515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323211501, states[0] = -95.042243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336593132, states[0] = -12.860331, states[40]= 0.001825
Saving checkpoint... 
Iteration: 1350660313, states[0] = -93.472064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1363976495, states[0] = -95.196763, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1373854929, states[0] = -95.167572, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1387245727, states[0] = -95.089865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1400899772, states[0] = -95.182197, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1414154579, states[0] = -87.336539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427628752, states[0] = -48.776823, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1437114656, states[0] = -33.751766, states[40]= 0.000302
Saving checkpoint... 
Iteration: 1450593262, states[0] = -12.981325, states[40]= 0.001804
Saving checkpoint... 
Iteration: 1464137445, states[0] = -59.273249, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1477516992, states[0] = 23.495301, states[40]= 0.015496
Saving checkpoint... 
Iteration: 1490909803, states[0] = -95.184680, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504334457, states[0] = -83.100785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1517295401, states[0] = -95.303864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1530727269, states[0] = -73.038813, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1544139097, states[0] = 14.027210, states[40]= 0.006562
Saving checkpoint... 
Iteration: 1557444041, states[0] = -94.953311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570482534, states[0] = -95.428510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583751405, states[0] = 7.317683, states[40]= 0.005750
Saving checkpoint... 
Iteration: 1597016311, states[0] = -58.316117, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1610074323, states[0] = -95.427581, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1623459278, states[0] = -95.260807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636758586, states[0] = -95.416120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1650023137, states[0] = 20.982529, states[40]= 0.010147
Saving checkpoint... 
Iteration: 1663261071, states[0] = 1.345939, states[40]= 0.005095
Saving checkpoint... 
Iteration: 1676574252, states[0] = -95.297140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689875823, states[0] = -95.430355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703251818, states[0] = -95.231998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1716300486, states[0] = -28.620078, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1729709329, states[0] = -95.360460, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743094895, states[0] = -32.125569, states[40]= 0.000365
Saving checkpoint... 
Iteration: 1752302346, states[0] = 46.103051, states[40]= 0.066425
Saving checkpoint... 
Iteration: 1765464817, states[0] = -95.422033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1778647802, states[0] = -95.406929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1792171507, states[0] = -95.427248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805291332, states[0] = -95.176553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1818478666, states[0] = -95.230324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1831977082, states[0] = -95.219542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1845162494, states[0] = -94.541662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858476115, states[0] = -95.207001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871565433, states[0] = 5.353759, states[40]= 0.004901
Saving checkpoint... 
Iteration: 1885105540, states[0] = -25.174769, states[40]= 0.000695
Saving checkpoint... 
Iteration: 1898311195, states[0] = -95.148937, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912101445, states[0] = -20.994666, states[40]= 0.000911
Saving checkpoint... 
Iteration: 1925799797, states[0] = -95.139780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1939509555, states[0] = 25.888736, states[40]= 0.059696
Saving checkpoint... 
Iteration: 1953028645, states[0] = 20.222470, states[40]= 0.007085
Saving checkpoint... 
Iteration: 1966361184, states[0] = -95.170125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1979839159, states[0] = -95.160757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993454262, states[0] = -95.193396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006796713, states[0] = -95.136266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020113798, states[0] = -32.905676, states[40]= 0.000335
Saving checkpoint... 
Iteration: 2033549600, states[0] = 12.412531, states[40]= 0.005286
Saving checkpoint... 
Iteration: 2046905729, states[0] = -95.183416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060132590, states[0] = -53.296190, states[40]= 0.000016
Saving checkpoint... 
Iteration: 2073497370, states[0] = -95.198885, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2083624874, states[0] = -44.397271, states[40]= 0.000067
Saving checkpoint... 
Iteration: 2096753469, states[0] = -95.098203, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -95.075017
 - CaMKt in component CaMK (millimolar): 0.006576
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.567855
 - nass in component intracellular_ions (millimolar): 6.567915
 - ki in component intracellular_ions (millimolar): 145.415901
 - kss in component intracellular_ions (millimolar): 145.415881
 - cansr in component intracellular_ions (millimolar): 1.290583
 - cajsr in component intracellular_ions (millimolar): 1.253160
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003556
 - hf in component INa (dimensionless): 0.882973
 - hs in component INa (dimensionless): 0.882969
 - j in component INa (dimensionless): 0.882943
 - hsp in component INa (dimensionless): 0.731458
 - jp in component INa (dimensionless): 0.882927
 - mL in component INaL (dimensionless): 0.000048
 - hL in component INaL (dimensionless): 0.715311
 - hLp in component INaL (dimensionless): 0.459805
 - a in component Ito (dimensionless): 0.000616
 - iF in component Ito (dimensionless): 0.999874
 - iS in component Ito (dimensionless): 0.624333
 - ap in component Ito (dimensionless): 0.000314
 - iFp in component Ito (dimensionless): 0.999874
 - iSp in component Ito (dimensionless): 0.699339
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.932423
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001533
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.343248
 - xs1 in component IKs (dimensionless): 0.243453
 - xs2 in component IKs (dimensionless): 0.000086
 - xk1 in component IK1 (dimensionless): 0.997291
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:24:02 (18360): called boinc_finish(0)

</stderr_txt>
]]>


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