𝕏

Task 56010034

Name HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_734_1
Workunit 26599408
Created 4 Jul 2024, 0:30:55 UTC
Sent 4 Jul 2024, 1:54:23 UTC
Report deadline 7 Jul 2024, 11:30:23 UTC
Received 6 Jul 2024, 0:09:15 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217971
Run time 1 hours 18 min 58 sec
CPU time 51 min 31 sec
Validate state Valid
Credit 61.85
Device peak FLOPS 5.38 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.21 MB
Peak swap size 5.26 MB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_734.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_734_1_r1170681536_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_734_1_r1170681536_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.791033
     * GNaL_b in INaL: 0.006169
     * Gto_b in Ito: 0.084231
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031354
     * GKs_b in IKs: 0.001979
     * GK1_b in IK1: 0.161641
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 71.444217
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030278
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 12127818, states[0] = -49.559326, states[40]= 0.000029
Saving checkpoint... 
Iteration: 24375606, states[0] = -95.041318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35508811, states[0] = 23.554620, states[40]= 0.069608
Saving checkpoint... 
Iteration: 47809977, states[0] = -94.973967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59732422, states[0] = -94.879951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 72114058, states[0] = -31.324801, states[40]= 0.000420
Saving checkpoint... 
Iteration: 81698644, states[0] = -94.807851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92458795, states[0] = -95.010486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103259456, states[0] = -94.903161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 114410297, states[0] = -94.996159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 125315491, states[0] = -94.952399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136403647, states[0] = -94.992436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 147038721, states[0] = 16.265959, states[40]= 0.005276
Saving checkpoint... 
Iteration: 158199272, states[0] = -94.800028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 169360716, states[0] = -94.975540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 180412448, states[0] = -94.993481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190958601, states[0] = -95.003557, states[40]= 0.000000
Saving checkpoint... 
Iteration: 201884424, states[0] = -94.984481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 213199806, states[0] = -94.800267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 224420235, states[0] = -94.995112, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235258496, states[0] = -94.896686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 246584376, states[0] = -4.419943, states[40]= 0.003498
Saving checkpoint... 
Iteration: 257523164, states[0] = 20.872047, states[40]= 0.007670
Saving checkpoint... 
Iteration: 268603380, states[0] = -20.679239, states[40]= 0.000935
Saving checkpoint... 
Iteration: 279419259, states[0] = -94.994710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 290553036, states[0] = 11.003299, states[40]= 0.004928
Saving checkpoint... 
Iteration: 301683847, states[0] = -94.754171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312137438, states[0] = -53.903532, states[40]= 0.000015
Saving checkpoint... 
Iteration: 322806986, states[0] = -94.943427, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333955473, states[0] = -95.002516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344464142, states[0] = -95.004028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 355438917, states[0] = -94.999231, states[40]= 0.000000
Saving checkpoint... 
Iteration: 366143190, states[0] = -60.287061, states[40]= 0.000005
Saving checkpoint... 
Iteration: 377648229, states[0] = -66.324007, states[40]= 0.000002
Saving checkpoint... 
Iteration: 388532345, states[0] = 18.382251, states[40]= 0.005743
Saving checkpoint... 
Iteration: 399697473, states[0] = -94.795026, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410676727, states[0] = -94.638607, states[40]= 0.000000
Saving checkpoint... 
Iteration: 421808537, states[0] = -94.944508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433003723, states[0] = 33.008922, states[40]= 0.154786
Saving checkpoint... 
Iteration: 444449597, states[0] = -95.001336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 455366251, states[0] = -94.977004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 466623275, states[0] = -39.278963, states[40]= 0.000149
Saving checkpoint... 
Iteration: 477540003, states[0] = 15.839234, states[40]= 0.005216
Saving checkpoint... 
Iteration: 488995949, states[0] = -95.008552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 499962636, states[0] = -95.003667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511062813, states[0] = 7.026661, states[40]= 0.004806
Saving checkpoint... 
Iteration: 521780648, states[0] = -94.920690, states[40]= 0.000000
Saving checkpoint... 
Iteration: 533283315, states[0] = -94.923255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 543819702, states[0] = -94.952226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 555065731, states[0] = 5.750400, states[40]= 0.004747
Saving checkpoint... 
Iteration: 565934319, states[0] = -94.998090, states[40]= 0.000000
Saving checkpoint... 
Iteration: 577189320, states[0] = -94.775688, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587913452, states[0] = -94.992953, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599608485, states[0] = -25.389921, states[40]= 0.000707
Saving checkpoint... 
Iteration: 610236463, states[0] = -94.866074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 621812513, states[0] = -94.947254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632349645, states[0] = -94.969313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 643568567, states[0] = 4.456086, states[40]= 0.004670
Saving checkpoint... 
Iteration: 654387501, states[0] = -94.984977, states[40]= 0.000000
Saving checkpoint... 
Iteration: 665789683, states[0] = -94.929034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677828768, states[0] = -94.957868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690056322, states[0] = 9.709155, states[40]= 0.004893
Saving checkpoint... 
Iteration: 702343118, states[0] = -94.965943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714530834, states[0] = 18.841806, states[40]= 0.005913
Saving checkpoint... 
Iteration: 726849657, states[0] = -94.969257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 739343471, states[0] = -94.966104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751236607, states[0] = -94.866202, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763616724, states[0] = -33.042234, states[40]= 0.000344
Saving checkpoint... 
Iteration: 775420312, states[0] = -94.994626, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787827676, states[0] = -94.957132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799733113, states[0] = -94.860741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 812305178, states[0] = -94.941732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824064121, states[0] = 6.460959, states[40]= 0.004782
Saving checkpoint... 
Iteration: 836368282, states[0] = -94.977602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 848269345, states[0] = -94.908765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860715322, states[0] = -94.830148, states[40]= 0.000000
Saving checkpoint... 
Iteration: 872400490, states[0] = -94.989046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884415626, states[0] = -94.993341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896210728, states[0] = -94.821450, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907757240, states[0] = -94.894588, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919912571, states[0] = -94.992498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932589636, states[0] = -8.380148, states[40]= 0.002663
Saving checkpoint... 
Iteration: 944466829, states[0] = -95.004079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956694416, states[0] = -94.787991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968722776, states[0] = -94.843473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 980899925, states[0] = -94.988802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 993276438, states[0] = -94.916176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005587059, states[0] = -6.361234, states[40]= 0.003097
Saving checkpoint... 
Iteration: 1017489988, states[0] = -95.007444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1029720208, states[0] = -94.838914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041886188, states[0] = -94.984269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054454547, states[0] = -95.001871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066433299, states[0] = -94.997536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1077563225, states[0] = 6.849633, states[40]= 0.004799
Saving checkpoint... 
Iteration: 1087787439, states[0] = -94.926734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099743818, states[0] = -94.876606, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110981258, states[0] = -95.006183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122803427, states[0] = -94.940181, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134597194, states[0] = -14.970904, states[40]= 0.001466
Saving checkpoint... 
Iteration: 1146539780, states[0] = 15.917518, states[40]= 0.005226
Saving checkpoint... 
Iteration: 1158209928, states[0] = -94.819736, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170019637, states[0] = 21.604518, states[40]= 0.009906
Saving checkpoint... 
Iteration: 1181687955, states[0] = -94.771200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1193327520, states[0] = -94.956772, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1204992546, states[0] = -95.007654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216814501, states[0] = -94.948261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228233665, states[0] = -94.861329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1240413582, states[0] = -94.992563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252447548, states[0] = -95.000410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264725780, states[0] = -94.848435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276765173, states[0] = -94.903807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1289263263, states[0] = -94.901591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301049768, states[0] = 12.258806, states[40]= 0.004967
Saving checkpoint... 
Iteration: 1313469114, states[0] = -95.004209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1325248045, states[0] = -94.882345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1337587287, states[0] = -6.533801, states[40]= 0.003060
Saving checkpoint... 
Iteration: 1349143583, states[0] = -60.736777, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1361497531, states[0] = -95.008178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372949613, states[0] = -95.000733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1385145317, states[0] = -62.760136, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1396868999, states[0] = -94.977531, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1409229853, states[0] = -94.855107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1421151448, states[0] = -70.610335, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1433447375, states[0] = -95.000258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445718710, states[0] = -94.835957, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457913115, states[0] = -94.992295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469220870, states[0] = -94.839800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1480843310, states[0] = -94.965536, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1492087591, states[0] = -6.765833, states[40]= 0.003010
Saving checkpoint... 
Iteration: 1504442083, states[0] = -95.183246, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1516066002, states[0] = -95.050046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528478187, states[0] = -95.244868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1539993619, states[0] = -27.956116, states[40]= 0.000570
Saving checkpoint... 
Iteration: 1552447438, states[0] = -95.230657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564673583, states[0] = -95.104410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577267131, states[0] = -95.089940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588735807, states[0] = -95.226163, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1601392082, states[0] = -95.282519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1613514475, states[0] = -52.319473, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1626070487, states[0] = -5.202451, states[40]= 0.003777
Saving checkpoint... 
Iteration: 1637704787, states[0] = 30.303338, states[40]= 0.132259
Saving checkpoint... 
Iteration: 1650264874, states[0] = -95.262379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662208017, states[0] = -95.187512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674820578, states[0] = -95.208505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686736712, states[0] = -85.222510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1699431737, states[0] = -95.224876, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711688526, states[0] = -95.149189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1724163743, states[0] = -0.104388, states[40]= 0.004776
Saving checkpoint... 
Iteration: 1735758645, states[0] = -95.256733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1748436686, states[0] = 14.596108, states[40]= 0.006291
Saving checkpoint... 
Iteration: 1760577245, states[0] = -95.123039, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1772927301, states[0] = -95.218701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784539130, states[0] = -89.058315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1795863321, states[0] = 0.181248, states[40]= 0.004820
Saving checkpoint... 
Iteration: 1807121960, states[0] = -41.667754, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1818025424, states[0] = 19.911829, states[40]= 0.006769
Saving checkpoint... 
Iteration: 1829626799, states[0] = -44.735282, states[40]= 0.000067
Saving checkpoint... 
Iteration: 1841455713, states[0] = -95.022379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1852598080, states[0] = -16.587331, states[40]= 0.001273
Saving checkpoint... 
Iteration: 1864610155, states[0] = -27.529518, states[40]= 0.000605
Saving checkpoint... 
Iteration: 1876261810, states[0] = -94.906955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888506871, states[0] = 25.195863, states[40]= 0.108198
Saving checkpoint... 
Iteration: 1899880397, states[0] = -94.985248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1911586509, states[0] = -6.055028, states[40]= 0.003164
Saving checkpoint... 
Iteration: 1922502599, states[0] = 39.809220, states[40]= 0.123304
Saving checkpoint... 
Iteration: 1934127238, states[0] = -43.286561, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1944839053, states[0] = -94.963868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956231137, states[0] = -94.857479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967503669, states[0] = 33.265290, states[40]= 0.154213
Saving checkpoint... 
Iteration: 1978844615, states[0] = -94.966189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1989824632, states[0] = -94.954660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2001431319, states[0] = -94.996602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012571542, states[0] = 3.026201, states[40]= 0.004562
Saving checkpoint... 
Iteration: 2024365636, states[0] = -94.975755, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2035730082, states[0] = -94.855079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047284735, states[0] = -94.923595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2058808706, states[0] = -94.943538, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070746004, states[0] = -94.879011, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2081871584, states[0] = -94.978091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093863200, states[0] = -94.974585, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883824
 - CaMKt in component CaMK (millimolar): 0.007071
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.553178
 - nass in component intracellular_ions (millimolar): 6.553239
 - ki in component intracellular_ions (millimolar): 145.423323
 - kss in component intracellular_ions (millimolar): 145.423303
 - cansr in component intracellular_ions (millimolar): 1.316335
 - cajsr in component intracellular_ions (millimolar): 1.278009
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879688
 - hs in component INa (dimensionless): 0.879683
 - j in component INa (dimensionless): 0.879653
 - hsp in component INa (dimensionless): 0.725239
 - jp in component INa (dimensionless): 0.879633
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708712
 - hLp in component INaL (dimensionless): 0.449304
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.618159
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.692353
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933137
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999878
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001621
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334929
 - xs1 in component IKs (dimensionless): 0.246060
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:09:00 (45896): called boinc_finish(0)

</stderr_txt>
]]>


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