𝕏

Task 56010024

Name HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_932_1
Workunit 26599403
Created 4 Jul 2024, 0:30:55 UTC
Sent 4 Jul 2024, 1:54:23 UTC
Report deadline 7 Jul 2024, 11:30:23 UTC
Received 6 Jul 2024, 1:36:11 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217971
Run time 1 hours 19 min 27 sec
CPU time 53 min 27 sec
Validate state Valid
Credit 61.78
Device peak FLOPS 5.38 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.22 MB
Peak swap size 5.27 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_932.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_932_1_r809787954_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023049631416_ORdGradInc_k_26-Pueyo_APDR-conf_932_1_r809787954_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.312418
     * GNaL_b in INaL: 0.005619
     * Gto_b in Ito: 0.081566
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032121
     * GKs_b in IKs: 0.001914
     * GK1_b in IK1: 0.160329
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.269010
     * GKb_b in IKb: 0.003773
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.034405
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11801068, states[0] = -95.046336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23721535, states[0] = -94.922086, states[40]= 0.000000
Saving checkpoint... 
Iteration: 35549075, states[0] = 11.236110, states[40]= 0.005027
Saving checkpoint... 
Iteration: 47389979, states[0] = -95.028359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58939554, states[0] = -95.033499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70377423, states[0] = -95.010956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81785172, states[0] = -94.952841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93335773, states[0] = -94.985805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104369763, states[0] = -94.999727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115514652, states[0] = 22.344912, states[40]= 0.019663
Saving checkpoint... 
Iteration: 127077208, states[0] = -1.410577, states[40]= 0.004061
Saving checkpoint... 
Iteration: 138324898, states[0] = -94.974628, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149938011, states[0] = -95.015954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 161318140, states[0] = -94.969501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172883030, states[0] = -95.000401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184273683, states[0] = -94.932799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195908141, states[0] = -95.007827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207286687, states[0] = -94.944879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 219021321, states[0] = 21.060287, states[40]= 0.008803
Saving checkpoint... 
Iteration: 230857727, states[0] = -94.989910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 242421761, states[0] = -95.011056, states[40]= 0.000000
Saving checkpoint... 
Iteration: 254199265, states[0] = -94.820900, states[40]= 0.000000
Saving checkpoint... 
Iteration: 265959614, states[0] = -95.018706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 277734522, states[0] = -94.883539, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289548555, states[0] = 12.051592, states[40]= 0.005032
Saving checkpoint... 
Iteration: 301241363, states[0] = -94.893480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312842764, states[0] = -94.982652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 324241221, states[0] = -94.893258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335903452, states[0] = -95.006093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347756195, states[0] = -94.912832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 359653709, states[0] = -80.828871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371317482, states[0] = -94.968016, states[40]= 0.000000
Saving checkpoint... 
Iteration: 383187848, states[0] = -94.795948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 394737111, states[0] = -94.887289, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406690114, states[0] = -94.801251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418109560, states[0] = -29.548865, states[40]= 0.000481
Saving checkpoint... 
Iteration: 429939222, states[0] = -95.014746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 441353814, states[0] = -94.987897, states[40]= 0.000000
Saving checkpoint... 
Iteration: 453379119, states[0] = -94.998183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 465020220, states[0] = 21.305461, states[40]= 0.009598
Saving checkpoint... 
Iteration: 476940256, states[0] = -95.014928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488549464, states[0] = 11.694465, states[40]= 0.005016
Saving checkpoint... 
Iteration: 500331231, states[0] = -94.976312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 511848360, states[0] = -94.985290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523612923, states[0] = -32.797532, states[40]= 0.000337
Saving checkpoint... 
Iteration: 535326191, states[0] = -94.973349, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547082535, states[0] = -4.884918, states[40]= 0.003427
Saving checkpoint... 
Iteration: 558926325, states[0] = -95.011851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570565296, states[0] = 4.970361, states[40]= 0.004734
Saving checkpoint... 
Iteration: 582385014, states[0] = -95.000167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594295560, states[0] = -94.951916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 605965899, states[0] = -95.019486, states[40]= 0.000000
Saving checkpoint... 
Iteration: 618109075, states[0] = -29.081755, states[40]= 0.000503
Saving checkpoint... 
Iteration: 629678083, states[0] = -94.755199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641470470, states[0] = -95.020180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652753402, states[0] = -94.909205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664380137, states[0] = -94.998416, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676056543, states[0] = 8.823569, states[40]= 0.004911
Saving checkpoint... 
Iteration: 687995636, states[0] = -95.023583, states[40]= 0.000000
Saving checkpoint... 
Iteration: 699658007, states[0] = -87.833058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 711425271, states[0] = -95.011510, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723268076, states[0] = -94.926139, states[40]= 0.000000
Saving checkpoint... 
Iteration: 734886951, states[0] = -95.000725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746768888, states[0] = -94.926991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758343413, states[0] = -94.982692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 770247470, states[0] = -94.901511, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782055842, states[0] = 9.115710, states[40]= 0.004921
Saving checkpoint... 
Iteration: 794028601, states[0] = 19.142859, states[40]= 0.006361
Saving checkpoint... 
Iteration: 806033079, states[0] = 17.732284, states[40]= 0.005776
Saving checkpoint... 
Iteration: 817698987, states[0] = -94.819913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829369052, states[0] = -94.994147, states[40]= 0.000000
Saving checkpoint... 
Iteration: 840796155, states[0] = -94.952242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852568637, states[0] = 3.363733, states[40]= 0.004619
Saving checkpoint... 
Iteration: 864212696, states[0] = -94.846568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 875901994, states[0] = -95.005329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887111691, states[0] = -31.604639, states[40]= 0.000387
Saving checkpoint... 
Iteration: 898694803, states[0] = -94.811166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909852204, states[0] = -94.986862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 921709263, states[0] = -94.840107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932774428, states[0] = -94.932601, states[40]= 0.000000
Saving checkpoint... 
Iteration: 944632092, states[0] = -52.487004, states[40]= 0.000018
Saving checkpoint... 
Iteration: 956038056, states[0] = 16.012786, states[40]= 0.005394
Saving checkpoint... 
Iteration: 967745233, states[0] = -94.898391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978965037, states[0] = -95.019114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990485639, states[0] = -95.022129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002013776, states[0] = 22.529127, states[40]= 0.023137
Saving checkpoint... 
Iteration: 1013539374, states[0] = 15.536482, states[40]= 0.005323
Saving checkpoint... 
Iteration: 1025069799, states[0] = 2.781049, states[40]= 0.004569
Saving checkpoint... 
Iteration: 1036575225, states[0] = -0.151130, states[40]= 0.004242
Saving checkpoint... 
Iteration: 1047905717, states[0] = -95.006285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1058984568, states[0] = -95.021943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1070380919, states[0] = -94.998440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1081869001, states[0] = -94.993969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093354789, states[0] = -94.987934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104503006, states[0] = 37.136302, states[40]= 0.134897
Saving checkpoint... 
Iteration: 1115816922, states[0] = -94.967182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127164822, states[0] = -93.553999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1138641949, states[0] = -63.713758, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1150584446, states[0] = -6.318188, states[40]= 0.003127
Saving checkpoint... 
Iteration: 1161771193, states[0] = -94.929153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1173531372, states[0] = 18.287511, states[40]= 0.005963
Saving checkpoint... 
Iteration: 1184890666, states[0] = -95.001665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196750472, states[0] = -94.905157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1208366892, states[0] = -94.993046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220171908, states[0] = -94.622753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231694408, states[0] = -94.810119, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1243403384, states[0] = -95.005501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255041553, states[0] = 14.733327, states[40]= 0.005226
Saving checkpoint... 
Iteration: 1266488021, states[0] = -95.022269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1278083493, states[0] = -5.592147, states[40]= 0.003281
Saving checkpoint... 
Iteration: 1289483670, states[0] = -95.021678, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1301114194, states[0] = -34.031569, states[40]= 0.000289
Saving checkpoint... 
Iteration: 1312242720, states[0] = -94.894728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1323912874, states[0] = -95.008055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335228659, states[0] = -94.873743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1346930092, states[0] = -95.012216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358172819, states[0] = -94.658780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1369603810, states[0] = -24.027760, states[40]= 0.000742
Saving checkpoint... 
Iteration: 1380923415, states[0] = -95.010655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392820047, states[0] = -94.969025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404062298, states[0] = 6.339889, states[40]= 0.004810
Saving checkpoint... 
Iteration: 1415704610, states[0] = -94.830810, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1427217165, states[0] = -94.854305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439042718, states[0] = 14.296756, states[40]= 0.005182
Saving checkpoint... 
Iteration: 1450716971, states[0] = -94.853945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1462246137, states[0] = -94.899300, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1473605843, states[0] = -25.976475, states[40]= 0.000651
Saving checkpoint... 
Iteration: 1485290229, states[0] = -94.946918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496662363, states[0] = -92.344978, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1508443678, states[0] = 11.513524, states[40]= 0.005854
Saving checkpoint... 
Iteration: 1519527099, states[0] = 18.781146, states[40]= 0.007778
Saving checkpoint... 
Iteration: 1531276940, states[0] = -12.157623, states[40]= 0.002166
Saving checkpoint... 
Iteration: 1542435608, states[0] = -86.937372, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1554109178, states[0] = -48.929450, states[40]= 0.000034
Saving checkpoint... 
Iteration: 1565058101, states[0] = -95.265739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1576665589, states[0] = -95.109530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588087549, states[0] = -95.164903, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599620888, states[0] = 20.656468, states[40]= 0.010389
Saving checkpoint... 
Iteration: 1610878755, states[0] = -95.147556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1622186395, states[0] = -23.835511, states[40]= 0.000772
Saving checkpoint... 
Iteration: 1633793958, states[0] = -95.303850, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1645283163, states[0] = -20.294289, states[40]= 0.001021
Saving checkpoint... 
Iteration: 1657130369, states[0] = -95.242790, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668397392, states[0] = -36.070489, states[40]= 0.000223
Saving checkpoint... 
Iteration: 1680132201, states[0] = -83.045702, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691501803, states[0] = -41.067015, states[40]= 0.000112
Saving checkpoint... 
Iteration: 1702996935, states[0] = -95.188652, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714381628, states[0] = -95.156321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1725977942, states[0] = -14.560105, states[40]= 0.001730
Saving checkpoint... 
Iteration: 1737403627, states[0] = -43.183838, states[40]= 0.000082
Saving checkpoint... 
Iteration: 1748938570, states[0] = -95.253741, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1760058736, states[0] = -95.275949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1771419401, states[0] = -95.227490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1782483369, states[0] = -95.160280, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793891972, states[0] = -95.178759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1805177815, states[0] = -94.811724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1816553969, states[0] = 9.094461, states[40]= 0.004969
Saving checkpoint... 
Iteration: 1827727779, states[0] = -94.903934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839413757, states[0] = -95.030617, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1850324008, states[0] = -94.987732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861979119, states[0] = -95.032358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873271720, states[0] = -94.937733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884934225, states[0] = -95.018716, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1896060400, states[0] = 7.090290, states[40]= 0.004847
Saving checkpoint... 
Iteration: 1907425476, states[0] = -95.013862, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918836035, states[0] = -94.980279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1930262446, states[0] = -94.920737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1941632929, states[0] = -53.488631, states[40]= 0.000015
Saving checkpoint... 
Iteration: 1952986871, states[0] = -95.022461, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1964635255, states[0] = -56.021725, states[40]= 0.000010
Saving checkpoint... 
Iteration: 1975999988, states[0] = -95.023662, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1987811241, states[0] = -94.963055, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999046074, states[0] = 13.013668, states[40]= 0.005085
Saving checkpoint... 
Iteration: 2010727761, states[0] = -94.871981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2022282109, states[0] = -94.939397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033874444, states[0] = -94.995499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2045306694, states[0] = -94.959550, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2056831461, states[0] = -94.975455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2068183071, states[0] = -94.781234, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079513733, states[0] = 22.537035, states[40]= 0.023328
Saving checkpoint... 
Iteration: 2090871312, states[0] = -94.994204, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.899051
 - CaMKt in component CaMK (millimolar): 0.006901
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.591488
 - nass in component intracellular_ions (millimolar): 6.591548
 - ki in component intracellular_ions (millimolar): 145.386981
 - kss in component intracellular_ions (millimolar): 145.386962
 - cansr in component intracellular_ions (millimolar): 1.308381
 - cajsr in component intracellular_ions (millimolar): 1.270616
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003620
 - hf in component INa (dimensionless): 0.879952
 - hs in component INa (dimensionless): 0.879948
 - j in component INa (dimensionless): 0.879919
 - hsp in component INa (dimensionless): 0.725739
 - jp in component INa (dimensionless): 0.879899
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710111
 - hLp in component INaL (dimensionless): 0.452707
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622493
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697533
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935799
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001590
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329553
 - xs1 in component IKs (dimensionless): 0.239704
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997338
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:35:58 (38032): called boinc_finish(0)

</stderr_txt>
]]>


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