𝕏

Task 56009782

Name HuVeMOp_20240704023042083776_ORdGradInc_k_26-Pueyo_APDR-conf_740_0
Workunit 26599283
Created 4 Jul 2024, 0:30:45 UTC
Sent 4 Jul 2024, 1:53:11 UTC
Report deadline 7 Jul 2024, 11:29:11 UTC
Received 4 Jul 2024, 5:59:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215734
Run time 2 hours 47 min 52 sec
CPU time 2 hours 41 min 32 sec
Validate state Valid
Credit 61.72
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.70 MB
Peak swap size 5.24 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023042083776_ORdGradInc_k_26-Pueyo_APDR-conf_740.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023042083776_ORdGradInc_k_26-Pueyo_APDR-conf_740_0_r687214795_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704023042083776_ORdGradInc_k_26-Pueyo_APDR-conf_740_0_r687214795_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.691544
     * GNaL_b in INaL: 0.005671
     * Gto_b in Ito: 0.085512
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031480
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.165177
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.024289
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029928
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9524012, states[0] = 19.297003, states[40]= 0.007462
Saving checkpoint... 
Iteration: 23036819, states[0] = 15.713985, states[40]= 0.005377
Saving checkpoint... 
Iteration: 36649597, states[0] = -75.261329, states[40]= 0.000000
Saving checkpoint... 
Iteration: 50598203, states[0] = -18.691956, states[40]= 0.001070
Saving checkpoint... 
Iteration: 64601429, states[0] = -21.263017, states[40]= 0.000894
Saving checkpoint... 
Iteration: 78377637, states[0] = -95.029464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 92116827, states[0] = -35.291998, states[40]= 0.000253
Saving checkpoint... 
Iteration: 105818872, states[0] = -94.994598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119589133, states[0] = -9.288090, states[40]= 0.002478
Saving checkpoint... 
Iteration: 133353912, states[0] = -95.011157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 142666533, states[0] = -93.637322, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156283647, states[0] = -94.963645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170233189, states[0] = -94.902570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 184210355, states[0] = -94.863216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 193840644, states[0] = -95.002875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 207563704, states[0] = 6.076074, states[40]= 0.004762
Saving checkpoint... 
Iteration: 221353749, states[0] = -95.009103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 235155635, states[0] = -80.784785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 248800630, states[0] = -94.976944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 262284826, states[0] = -94.963634, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276170646, states[0] = -94.449789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289986470, states[0] = -95.043929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 303939278, states[0] = -95.036001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317970788, states[0] = -95.041646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331749718, states[0] = -94.925162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 345564461, states[0] = 5.744351, states[40]= 0.004745
Saving checkpoint... 
Iteration: 355076142, states[0] = -0.088756, states[40]= 0.004228
Saving checkpoint... 
Iteration: 368893794, states[0] = -95.024222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 382857421, states[0] = -95.010507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 396518877, states[0] = 21.395061, states[40]= 0.010678
Saving checkpoint... 
Iteration: 410290545, states[0] = -94.968541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424066699, states[0] = 4.725561, states[40]= 0.004687
Saving checkpoint... 
Iteration: 437821339, states[0] = -94.991258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 451617196, states[0] = -35.202613, states[40]= 0.000256
Saving checkpoint... 
Iteration: 465368665, states[0] = -95.015201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 479160562, states[0] = -88.827213, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492893644, states[0] = -95.024092, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506652924, states[0] = -76.136127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520056582, states[0] = 9.095426, states[40]= 0.004874
Saving checkpoint... 
Iteration: 533701629, states[0] = -94.845464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547572042, states[0] = 2.123539, states[40]= 0.004481
Saving checkpoint... 
Iteration: 561280232, states[0] = -94.959115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 575132247, states[0] = -50.426890, states[40]= 0.000026
Saving checkpoint... 
Iteration: 589057469, states[0] = 8.733173, states[40]= 0.004863
Saving checkpoint... 
Iteration: 602980239, states[0] = -95.042848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616852319, states[0] = -95.008024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 630785332, states[0] = -94.963803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 644483871, states[0] = -95.043326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 658336531, states[0] = -95.000025, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672431196, states[0] = -95.034007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 686653055, states[0] = -76.351356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700836423, states[0] = -94.999939, states[40]= 0.000000
Saving checkpoint... 
Iteration: 714709863, states[0] = -94.861458, states[40]= 0.000000
Saving checkpoint... 
Iteration: 728464823, states[0] = -95.040421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742018520, states[0] = 21.459913, states[40]= 0.011101
Saving checkpoint... 
Iteration: 755866966, states[0] = -95.014325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 765389604, states[0] = -95.022610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779344672, states[0] = -95.004207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 793395355, states[0] = -95.024432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 807398541, states[0] = -95.025401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821468397, states[0] = -95.040934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 835344935, states[0] = -95.004303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 849078268, states[0] = -1.332903, states[40]= 0.004050
Saving checkpoint... 
Iteration: 862932097, states[0] = -95.034082, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876731527, states[0] = -94.898814, states[40]= 0.000000
Saving checkpoint... 
Iteration: 890617978, states[0] = -35.952989, states[40]= 0.000231
Saving checkpoint... 
Iteration: 904376131, states[0] = -95.017798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 917972920, states[0] = -95.041571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 931734973, states[0] = -94.904068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 945613985, states[0] = -32.143747, states[40]= 0.000374
Saving checkpoint... 
Iteration: 959367745, states[0] = -95.014507, states[40]= 0.000000
Saving checkpoint... 
Iteration: 972985984, states[0] = -95.043396, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986575916, states[0] = 0.039555, states[40]= 0.004245
Saving checkpoint... 
Iteration: 1000198198, states[0] = -94.838151, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014082348, states[0] = -3.956269, states[40]= 0.003593
Saving checkpoint... 
Iteration: 1027953629, states[0] = -95.038297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1041315340, states[0] = -94.986961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1054967847, states[0] = -95.040694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068751522, states[0] = -94.926997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1082430803, states[0] = -95.033651, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1096219135, states[0] = -94.878135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1110024401, states[0] = 20.214854, states[40]= 0.007201
Saving checkpoint... 
Iteration: 1123686697, states[0] = -94.811927, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137339502, states[0] = -95.001306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1150941459, states[0] = -95.035880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1164660231, states[0] = -88.372722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178614007, states[0] = -32.164461, states[40]= 0.000373
Saving checkpoint... 
Iteration: 1192445874, states[0] = -95.036731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206242566, states[0] = -94.914926, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220143766, states[0] = -63.348300, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1233854473, states[0] = -95.008616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247620961, states[0] = -38.846313, states[40]= 0.000155
Saving checkpoint... 
Iteration: 1261320386, states[0] = -94.990113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275167096, states[0] = -93.777338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288980167, states[0] = -95.042389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1302680556, states[0] = -94.786428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1314233298, states[0] = -94.901267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328052940, states[0] = 10.552004, states[40]= 0.004916
Saving checkpoint... 
Iteration: 1341915775, states[0] = -95.029867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355647125, states[0] = -67.590436, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1369455060, states[0] = -95.038331, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1383031525, states[0] = 18.237824, states[40]= 0.005824
Saving checkpoint... 
Iteration: 1396456408, states[0] = -95.038553, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410230939, states[0] = -94.897542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424148437, states[0] = -69.365802, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1434167200, states[0] = -93.808351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1447824325, states[0] = -94.992453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1461045918, states[0] = 13.245045, states[40]= 0.005024
Saving checkpoint... 
Iteration: 1474747267, states[0] = -94.921174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488240277, states[0] = -94.911501, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501949606, states[0] = -94.487826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1515206908, states[0] = -95.175969, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528261185, states[0] = 1.705652, states[40]= 0.004993
Saving checkpoint... 
Iteration: 1541792133, states[0] = -27.901233, states[40]= 0.000564
Saving checkpoint... 
Iteration: 1555733565, states[0] = -95.246060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1569684981, states[0] = -20.777567, states[40]= 0.000984
Saving checkpoint... 
Iteration: 1583456498, states[0] = 3.994993, states[40]= 0.005266
Saving checkpoint... 
Iteration: 1597334715, states[0] = -84.817176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611152765, states[0] = -95.040357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624870527, states[0] = -6.164592, states[40]= 0.003551
Saving checkpoint... 
Iteration: 1638645698, states[0] = 9.829052, states[40]= 0.005747
Saving checkpoint... 
Iteration: 1652324307, states[0] = -95.245235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1665858628, states[0] = -95.286586, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679613953, states[0] = -95.229692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1689195891, states[0] = -95.197366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702684639, states[0] = -95.173807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1715872871, states[0] = -95.146033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729719984, states[0] = -95.239273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1743557665, states[0] = -95.285880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1757230264, states[0] = -76.940091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1770853199, states[0] = -95.281309, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784283320, states[0] = -95.170883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1793786772, states[0] = -23.134025, states[40]= 0.000821
Saving checkpoint... 
Iteration: 1807725673, states[0] = -94.935470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821608866, states[0] = -29.546853, states[40]= 0.000496
Saving checkpoint... 
Iteration: 1835396453, states[0] = -95.048287, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1848404344, states[0] = -95.042893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861031981, states[0] = 17.954286, states[40]= 0.005766
Saving checkpoint... 
Iteration: 1874340383, states[0] = -95.008904, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887352433, states[0] = -95.012402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1899844513, states[0] = -95.006943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1912640119, states[0] = -59.281486, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1926123436, states[0] = -41.405466, states[40]= 0.000106
Saving checkpoint... 
Iteration: 1939809015, states[0] = -94.983057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953288265, states[0] = -94.966243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1966723426, states[0] = -94.885399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1980284777, states[0] = -94.962696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993540207, states[0] = 15.332286, states[40]= 0.005201
Saving checkpoint... 
Iteration: 2006824795, states[0] = -94.992471, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2020158205, states[0] = -85.245505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2033806305, states[0] = -94.979992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046788787, states[0] = -94.965934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060587254, states[0] = -7.597362, states[40]= 0.002836
Saving checkpoint... 
Iteration: 2073692765, states[0] = -94.825869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2087586290, states[0] = -6.837204, states[40]= 0.003000
Saving checkpoint... 
Iteration: 2099919217, states[0] = -95.030195, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.920245
 - CaMKt in component CaMK (millimolar): 0.007036
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.556092
 - nass in component intracellular_ions (millimolar): 6.556152
 - ki in component intracellular_ions (millimolar): 145.420599
 - kss in component intracellular_ions (millimolar): 145.420579
 - cansr in component intracellular_ions (millimolar): 1.315221
 - cajsr in component intracellular_ions (millimolar): 1.277104
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003612
 - hf in component INa (dimensionless): 0.880320
 - hs in component INa (dimensionless): 0.880315
 - j in component INa (dimensionless): 0.880286
 - hsp in component INa (dimensionless): 0.726431
 - jp in component INa (dimensionless): 0.880266
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710209
 - hLp in component INaL (dimensionless): 0.451980
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620578
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695386
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935051
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001615
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330490
 - xs1 in component IKs (dimensionless): 0.242384
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997332
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
15:33:43 (6832): called boinc_finish(0)

</stderr_txt>
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