𝕏

Task 56009606

Name HuVeMOp_20240704022552772307_ORdGradInc_k_26-Pueyo_APDR-conf_773_1
Workunit 26599200
Created 4 Jul 2024, 0:26:03 UTC
Sent 4 Jul 2024, 1:49:35 UTC
Report deadline 7 Jul 2024, 11:25:35 UTC
Received 5 Jul 2024, 9:32:24 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241447
Run time 1 hours 46 min 7 sec
CPU time 1 hours 25 min 22 sec
Validate state Valid
Credit 64.34
Device peak FLOPS 2.97 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.71 MB
Peak swap size 5.31 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704022552772307_ORdGradInc_k_26-Pueyo_APDR-conf_773.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704022552772307_ORdGradInc_k_26-Pueyo_APDR-conf_773_1_r799590077_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704022552772307_ORdGradInc_k_26-Pueyo_APDR-conf_773_1_r799590077_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.259655
     * GNaL_b in INaL: 0.005505
     * Gto_b in Ito: 0.086746
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031984
     * GKs_b in IKs: 0.001931
     * GK1_b in IK1: 0.164612
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.604201
     * GKb_b in IKb: 0.003833
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032850
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19602790, states[0] = -26.226397, states[40]= 0.000621
Saving checkpoint... 
Iteration: 38906502, states[0] = -95.039822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57867699, states[0] = -95.010722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 77659846, states[0] = -90.329173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97366416, states[0] = -94.996266, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115751968, states[0] = -94.908261, states[40]= 0.000000
Saving checkpoint... 
Iteration: 135228508, states[0] = -94.873305, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154299931, states[0] = -94.953573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172716328, states[0] = -94.851347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 191915770, states[0] = -95.006456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209994130, states[0] = -95.020433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229855560, states[0] = -94.985603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250956947, states[0] = -95.014816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 270921262, states[0] = -95.007435, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289791068, states[0] = -94.945212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 308346014, states[0] = -94.980961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 327512108, states[0] = 22.209238, states[40]= 0.032249
Saving checkpoint... 
Iteration: 347014682, states[0] = 21.801031, states[40]= 0.019220
Saving checkpoint... 
Iteration: 366393645, states[0] = -94.999725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 384167604, states[0] = -94.145639, states[40]= 0.000000
Saving checkpoint... 
Iteration: 400247532, states[0] = -94.898778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 413818933, states[0] = -94.965658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433962264, states[0] = -95.015532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454093069, states[0] = -13.436843, states[40]= 0.001692
Saving checkpoint... 
Iteration: 474154577, states[0] = -80.961768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494586253, states[0] = -7.515036, states[40]= 0.002846
Saving checkpoint... 
Iteration: 514217073, states[0] = -94.851782, states[40]= 0.000000
Saving checkpoint... 
Iteration: 534636115, states[0] = -55.969415, states[40]= 0.000010
Saving checkpoint... 
Iteration: 554424586, states[0] = -95.008004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 573876352, states[0] = -94.993714, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594335871, states[0] = -94.975524, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613900097, states[0] = -95.001519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631476400, states[0] = -95.017585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648528207, states[0] = 18.934200, states[40]= 0.006232
Saving checkpoint... 
Iteration: 665556594, states[0] = 8.743249, states[40]= 0.004837
Saving checkpoint... 
Iteration: 683019308, states[0] = 21.038985, states[40]= 0.010113
Saving checkpoint... 
Iteration: 699166932, states[0] = -94.004987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 716524817, states[0] = 19.835858, states[40]= 0.007001
Saving checkpoint... 
Iteration: 734247305, states[0] = -94.898256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 751745232, states[0] = -94.895474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769288491, states[0] = -94.942667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 786205319, states[0] = -94.829695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802467670, states[0] = -95.016158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 819662187, states[0] = -91.765739, states[40]= 0.000000
Saving checkpoint... 
Iteration: 837091809, states[0] = -12.285337, states[40]= 0.001886
Saving checkpoint... 
Iteration: 854501540, states[0] = 47.278560, states[40]= 0.065013
Saving checkpoint... 
Iteration: 872060213, states[0] = 7.229784, states[40]= 0.004786
Saving checkpoint... 
Iteration: 888562701, states[0] = 6.150024, states[40]= 0.004741
Saving checkpoint... 
Iteration: 905863859, states[0] = -94.988615, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923257489, states[0] = -94.910921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940703209, states[0] = -94.825443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958249958, states[0] = -94.901569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 974988795, states[0] = -95.019048, states[40]= 0.000000
Saving checkpoint... 
Iteration: 992555609, states[0] = 9.145258, states[40]= 0.004849
Saving checkpoint... 
Iteration: 1010174529, states[0] = -94.696338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1027530767, states[0] = 18.183718, states[40]= 0.005861
Saving checkpoint... 
Iteration: 1044701620, states[0] = -94.822207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1061968890, states[0] = -95.016178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1078619870, states[0] = -38.939134, states[40]= 0.000149
Saving checkpoint... 
Iteration: 1096290672, states[0] = -94.944323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113584931, states[0] = -6.475527, states[40]= 0.003068
Saving checkpoint... 
Iteration: 1131248987, states[0] = -94.900199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148883286, states[0] = -94.995805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1165326715, states[0] = -94.969955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183055434, states[0] = 9.216308, states[40]= 0.004851
Saving checkpoint... 
Iteration: 1200543335, states[0] = 13.889690, states[40]= 0.005051
Saving checkpoint... 
Iteration: 1218248401, states[0] = -94.899377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235717009, states[0] = -94.851190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252575474, states[0] = -0.193324, states[40]= 0.004198
Saving checkpoint... 
Iteration: 1269149189, states[0] = -72.160361, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1286477684, states[0] = -95.017338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1304117264, states[0] = -36.390257, states[40]= 0.000213
Saving checkpoint... 
Iteration: 1321774775, states[0] = -94.929530, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339356165, states[0] = -94.985022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356047911, states[0] = 12.171100, states[40]= 0.004949
Saving checkpoint... 
Iteration: 1373541403, states[0] = 14.597891, states[40]= 0.005113
Saving checkpoint... 
Iteration: 1391122773, states[0] = -41.833123, states[40]= 0.000097
Saving checkpoint... 
Iteration: 1407936199, states[0] = -95.010022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1422780996, states[0] = -94.935478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436486253, states[0] = -95.018414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1451433897, states[0] = -95.009504, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1466451795, states[0] = -95.013038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481126229, states[0] = -45.369355, states[40]= 0.000057
Saving checkpoint... 
Iteration: 1495412521, states[0] = -95.004392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1509133705, states[0] = -79.304388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523570571, states[0] = -95.085692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538331755, states[0] = -95.212719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1553093003, states[0] = -95.279769, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1567833762, states[0] = 15.362127, states[40]= 0.006485
Saving checkpoint... 
Iteration: 1582812249, states[0] = 22.701420, states[40]= 0.032727
Saving checkpoint... 
Iteration: 1596878147, states[0] = -95.279079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611589967, states[0] = -95.289108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1626721739, states[0] = -65.131921, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1642738911, states[0] = -95.242778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1660185413, states[0] = -95.287389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1676713391, states[0] = 22.349521, states[40]= 0.026190
Saving checkpoint... 
Iteration: 1693802727, states[0] = 39.260746, states[40]= 0.104388
Saving checkpoint... 
Iteration: 1711116636, states[0] = -95.212598, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1728105952, states[0] = -45.486326, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1745603802, states[0] = -95.191098, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762169616, states[0] = -95.275067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1779629749, states[0] = 16.981130, states[40]= 0.006994
Saving checkpoint... 
Iteration: 1797212453, states[0] = -95.205916, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1814841260, states[0] = -95.020669, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1832349642, states[0] = -95.008371, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849503695, states[0] = 32.368844, states[40]= 0.158201
Saving checkpoint... 
Iteration: 1866262012, states[0] = -94.925388, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1883358577, states[0] = -94.991516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900626622, states[0] = -46.018866, states[40]= 0.000051
Saving checkpoint... 
Iteration: 1917845338, states[0] = -94.981595, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934710582, states[0] = -94.840243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1950459431, states[0] = -95.014796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1967349687, states[0] = -94.982054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984552608, states[0] = 10.342490, states[40]= 0.004884
Saving checkpoint... 
Iteration: 2001615659, states[0] = -34.848226, states[40]= 0.000261
Saving checkpoint... 
Iteration: 2018576303, states[0] = -0.676142, states[40]= 0.004132
Saving checkpoint... 
Iteration: 2034939383, states[0] = -95.010276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2051623135, states[0] = -42.200895, states[40]= 0.000092
Saving checkpoint... 
Iteration: 2068227397, states[0] = -94.868193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084717019, states[0] = -94.850600, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.895498
 - CaMKt in component CaMK (millimolar): 0.006986
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.553373
 - nass in component intracellular_ions (millimolar): 6.553433
 - ki in component intracellular_ions (millimolar): 145.424008
 - kss in component intracellular_ions (millimolar): 145.423989
 - cansr in component intracellular_ions (millimolar): 1.311743
 - cajsr in component intracellular_ions (millimolar): 1.273774
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879890
 - hs in component INa (dimensionless): 0.879886
 - j in component INa (dimensionless): 0.879857
 - hsp in component INa (dimensionless): 0.725623
 - jp in component INa (dimensionless): 0.879838
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709851
 - hLp in component INaL (dimensionless): 0.452115
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621727
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696821
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936393
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001598
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326121
 - xs1 in component IKs (dimensionless): 0.239968
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
02:32:16 (18660): called boinc_finish(0)

</stderr_txt>
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