𝕏

Task 56009047

Name HuVeMOp_20240704022051822265_ORdGradInc_k_26-Pueyo_APDR-conf_679_1
Workunit 26598952
Created 4 Jul 2024, 0:21:00 UTC
Sent 4 Jul 2024, 1:54:23 UTC
Report deadline 7 Jul 2024, 11:30:23 UTC
Received 6 Jul 2024, 2:16:00 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 217971
Run time 1 hours 18 min 52 sec
CPU time 57 min 4 sec
Validate state Valid
Credit 60.90
Device peak FLOPS 5.38 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.20 MB
Peak swap size 5.26 MB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704022051822265_ORdGradInc_k_26-Pueyo_APDR-conf_679.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704022051822265_ORdGradInc_k_26-Pueyo_APDR-conf_679_1_r607066609_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704022051822265_ORdGradInc_k_26-Pueyo_APDR-conf_679_1_r607066609_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.613198
     * GNaL_b in INaL: 0.005895
     * Gto_b in Ito: 0.083043
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031983
     * GKs_b in IKs: 0.001884
     * GK1_b in IK1: 0.160652
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 70.707145
     * GKb_b in IKb: 0.003816
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029350
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 11510880, states[0] = 22.468915, states[40]= 0.043015
Saving checkpoint... 
Iteration: 22652017, states[0] = -82.794260, states[40]= 0.000000
Saving checkpoint... 
Iteration: 34511769, states[0] = 22.572823, states[40]= 0.035168
Saving checkpoint... 
Iteration: 45705540, states[0] = -94.821526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 57552745, states[0] = 10.141601, states[40]= 0.004969
Saving checkpoint... 
Iteration: 68748069, states[0] = -94.877150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80529004, states[0] = 18.897303, states[40]= 0.006282
Saving checkpoint... 
Iteration: 91982811, states[0] = -94.992091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 103683324, states[0] = -94.745330, states[40]= 0.000000
Saving checkpoint... 
Iteration: 115212960, states[0] = -94.810152, states[40]= 0.000000
Saving checkpoint... 
Iteration: 126829936, states[0] = -94.940063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 138168354, states[0] = -94.124187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 149608643, states[0] = -27.927644, states[40]= 0.000567
Saving checkpoint... 
Iteration: 161105008, states[0] = -24.471522, states[40]= 0.000731
Saving checkpoint... 
Iteration: 172600451, states[0] = -20.153481, states[40]= 0.000960
Saving checkpoint... 
Iteration: 183741819, states[0] = -94.854592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195007047, states[0] = 25.151616, states[40]= 0.103725
Saving checkpoint... 
Iteration: 206371717, states[0] = -94.958028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217741325, states[0] = -94.853562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 229201035, states[0] = -94.783250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240254692, states[0] = -94.871456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251799401, states[0] = -94.916542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 263575968, states[0] = -0.327147, states[40]= 0.004217
Saving checkpoint... 
Iteration: 275119056, states[0] = -37.828774, states[40]= 0.000177
Saving checkpoint... 
Iteration: 286921115, states[0] = -94.973362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 298148359, states[0] = -70.425500, states[40]= 0.000001
Saving checkpoint... 
Iteration: 309794341, states[0] = -94.912313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 321458494, states[0] = -94.981167, states[40]= 0.000000
Saving checkpoint... 
Iteration: 333162947, states[0] = -91.802881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 344533328, states[0] = 17.654758, states[40]= 0.005749
Saving checkpoint... 
Iteration: 356360562, states[0] = -94.953053, states[40]= 0.000000
Saving checkpoint... 
Iteration: 367755634, states[0] = -94.872466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379414324, states[0] = -94.971541, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391066793, states[0] = 4.435403, states[40]= 0.004698
Saving checkpoint... 
Iteration: 402422241, states[0] = -94.973546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 414134228, states[0] = -53.574049, states[40]= 0.000015
Saving checkpoint... 
Iteration: 425415480, states[0] = -94.971815, states[40]= 0.000000
Saving checkpoint... 
Iteration: 436928916, states[0] = -94.975115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448043395, states[0] = 14.091531, states[40]= 0.005158
Saving checkpoint... 
Iteration: 459682374, states[0] = -94.735389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 471027366, states[0] = 19.481671, states[40]= 0.006592
Saving checkpoint... 
Iteration: 482454873, states[0] = -94.980412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493743123, states[0] = -94.855778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 505346291, states[0] = -94.946245, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516609618, states[0] = -28.777909, states[40]= 0.000526
Saving checkpoint... 
Iteration: 528158366, states[0] = -86.428748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 539546238, states[0] = 13.016925, states[40]= 0.005080
Saving checkpoint... 
Iteration: 551326955, states[0] = -94.935515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562725038, states[0] = -94.827761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 574200782, states[0] = -94.782390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 585505666, states[0] = 27.158561, states[40]= 0.134308
Saving checkpoint... 
Iteration: 597317058, states[0] = -94.929175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 608644209, states[0] = -64.992293, states[40]= 0.000002
Saving checkpoint... 
Iteration: 620433604, states[0] = -94.976059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631574004, states[0] = 0.779978, states[40]= 0.004360
Saving checkpoint... 
Iteration: 643315068, states[0] = -94.927801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 654550861, states[0] = 11.225317, states[40]= 0.004993
Saving checkpoint... 
Iteration: 666340060, states[0] = -94.942911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677497745, states[0] = -94.986682, states[40]= 0.000000
Saving checkpoint... 
Iteration: 689194379, states[0] = -94.768881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 700471764, states[0] = -94.983107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 712032064, states[0] = 18.064249, states[40]= 0.005880
Saving checkpoint... 
Iteration: 723635651, states[0] = -55.132889, states[40]= 0.000012
Saving checkpoint... 
Iteration: 735050363, states[0] = 11.421099, states[40]= 0.005000
Saving checkpoint... 
Iteration: 746571981, states[0] = 1.863269, states[40]= 0.004481
Saving checkpoint... 
Iteration: 758394677, states[0] = -94.965593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769587118, states[0] = -8.012079, states[40]= 0.002760
Saving checkpoint... 
Iteration: 781294369, states[0] = -94.912028, states[40]= 0.000000
Saving checkpoint... 
Iteration: 792924895, states[0] = -94.973944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804511527, states[0] = 22.894862, states[40]= 0.037303
Saving checkpoint... 
Iteration: 815812548, states[0] = -94.925951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 827506372, states[0] = 25.980811, states[40]= 0.118805
Saving checkpoint... 
Iteration: 838810136, states[0] = -94.924228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850366841, states[0] = -94.955414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861810851, states[0] = -94.924725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 873251790, states[0] = -94.867265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884964267, states[0] = -94.981789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 896207186, states[0] = -94.795006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 907699315, states[0] = -94.779161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 919094696, states[0] = -14.700629, states[40]= 0.001511
Saving checkpoint... 
Iteration: 930601258, states[0] = -20.880046, states[40]= 0.000914
Saving checkpoint... 
Iteration: 942025171, states[0] = 20.079138, states[40]= 0.007133
Saving checkpoint... 
Iteration: 953596766, states[0] = -16.638663, states[40]= 0.001266
Saving checkpoint... 
Iteration: 965027377, states[0] = 19.478660, states[40]= 0.006590
Saving checkpoint... 
Iteration: 976759267, states[0] = -94.876519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987896376, states[0] = -94.965984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999584575, states[0] = -6.013998, states[40]= 0.003190
Saving checkpoint... 
Iteration: 1010791057, states[0] = -94.909057, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1022653175, states[0] = -77.760503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033923694, states[0] = -94.973503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1045575439, states[0] = -0.022070, states[40]= 0.004259
Saving checkpoint... 
Iteration: 1056761745, states[0] = -94.879403, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1068462104, states[0] = -94.981311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079595158, states[0] = -15.131083, states[40]= 0.001451
Saving checkpoint... 
Iteration: 1090975668, states[0] = -94.983454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102203289, states[0] = -94.787141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114216009, states[0] = -94.811562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1125600305, states[0] = -19.979401, states[40]= 0.000971
Saving checkpoint... 
Iteration: 1137337175, states[0] = -94.941051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1148669146, states[0] = -94.230070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1160794493, states[0] = -94.911892, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171919582, states[0] = -94.972399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183562129, states[0] = 6.558452, states[40]= 0.004819
Saving checkpoint... 
Iteration: 1194825659, states[0] = -94.934317, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1206168599, states[0] = -94.141791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1217489938, states[0] = -94.985364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1229145613, states[0] = -66.756486, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1240915996, states[0] = -94.971436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252135327, states[0] = -54.776278, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1263691741, states[0] = -94.762695, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1275023727, states[0] = 20.446805, states[40]= 0.007619
Saving checkpoint... 
Iteration: 1286768347, states[0] = -94.886723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298103569, states[0] = -23.061950, states[40]= 0.000798
Saving checkpoint... 
Iteration: 1310022672, states[0] = 20.702004, states[40]= 0.008071
Saving checkpoint... 
Iteration: 1321708256, states[0] = -94.796821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1333893305, states[0] = -94.964791, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1345589903, states[0] = -10.362488, states[40]= 0.002266
Saving checkpoint... 
Iteration: 1357538386, states[0] = 15.922473, states[40]= 0.005373
Saving checkpoint... 
Iteration: 1369311589, states[0] = -94.924928, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381539809, states[0] = 15.412276, states[40]= 0.005300
Saving checkpoint... 
Iteration: 1393361824, states[0] = -94.952948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405402811, states[0] = -94.967676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1417494778, states[0] = -94.985853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1429689485, states[0] = -94.757335, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1441531674, states[0] = 18.188499, states[40]= 0.005925
Saving checkpoint... 
Iteration: 1453465847, states[0] = -94.981692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1465592939, states[0] = -13.078489, states[40]= 0.001762
Saving checkpoint... 
Iteration: 1477405243, states[0] = -94.968340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1489490222, states[0] = -94.985229, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501505683, states[0] = 28.557928, states[40]= 0.103480
Saving checkpoint... 
Iteration: 1513641457, states[0] = -91.076392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1525181274, states[0] = -95.225115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537383956, states[0] = -95.098754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1549110468, states[0] = -95.158457, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1561034516, states[0] = -84.272414, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1572293003, states[0] = -95.259715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1583959509, states[0] = -95.234075, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595708625, states[0] = 24.857707, states[40]= 0.071040
Saving checkpoint... 
Iteration: 1607872502, states[0] = -95.092157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1619455920, states[0] = 4.060702, states[40]= 0.005303
Saving checkpoint... 
Iteration: 1631417134, states[0] = 21.774476, states[40]= 0.015011
Saving checkpoint... 
Iteration: 1643055382, states[0] = -95.234232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1655092163, states[0] = -95.266054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667017103, states[0] = -95.185052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1679381675, states[0] = -95.258529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1691257870, states[0] = -95.045503, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1703327595, states[0] = -95.200999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1714979154, states[0] = -95.110732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727049062, states[0] = -95.228052, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1738984983, states[0] = -95.124205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1751157353, states[0] = 3.160859, states[40]= 0.005212
Saving checkpoint... 
Iteration: 1762835571, states[0] = 14.670448, states[40]= 0.006455
Saving checkpoint... 
Iteration: 1774768903, states[0] = -95.247944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786663284, states[0] = -95.068637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1798635099, states[0] = -86.365730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1810472539, states[0] = -95.032570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1822134739, states[0] = -56.917052, states[40]= 0.000009
Saving checkpoint... 
Iteration: 1834062711, states[0] = 5.749236, states[40]= 0.004802
Saving checkpoint... 
Iteration: 1845812783, states[0] = -94.944101, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1857715746, states[0] = -94.823911, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1869463703, states[0] = -94.990211, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881618098, states[0] = -37.282420, states[40]= 0.000191
Saving checkpoint... 
Iteration: 1893313813, states[0] = -94.930654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905626349, states[0] = -45.379337, states[40]= 0.000058
Saving checkpoint... 
Iteration: 1917330556, states[0] = -94.938982, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1929451742, states[0] = -94.980426, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1940796234, states[0] = -94.913914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1953064950, states[0] = 5.275760, states[40]= 0.004752
Saving checkpoint... 
Iteration: 1964843690, states[0] = -94.944494, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976989755, states[0] = -94.985190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1988843295, states[0] = -94.943996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2000756189, states[0] = -94.872259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2012756991, states[0] = -94.873182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2024929845, states[0] = -94.974368, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036541421, states[0] = 14.823556, states[40]= 0.005229
Saving checkpoint... 
Iteration: 2048667432, states[0] = -93.900006, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2060245344, states[0] = -94.857869, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2072356673, states[0] = -94.950199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084182655, states[0] = -94.735603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096029892, states[0] = 18.741460, states[40]= 0.006156
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.861888
 - CaMKt in component CaMK (millimolar): 0.006951
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.583237
 - nass in component intracellular_ions (millimolar): 6.583297
 - ki in component intracellular_ions (millimolar): 145.394577
 - kss in component intracellular_ions (millimolar): 145.394557
 - cansr in component intracellular_ions (millimolar): 1.311352
 - cajsr in component intracellular_ions (millimolar): 1.273444
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003633
 - hf in component INa (dimensionless): 0.879306
 - hs in component INa (dimensionless): 0.879301
 - j in component INa (dimensionless): 0.879271
 - hsp in component INa (dimensionless): 0.724521
 - jp in component INa (dimensionless): 0.879251
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708843
 - hLp in component INaL (dimensionless): 0.450748
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.621084
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695842
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935389
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999886
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001602
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332782
 - xs1 in component IKs (dimensionless): 0.240994
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997348
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
16:15:51 (23952): called boinc_finish(0)

</stderr_txt>
]]>


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