𝕏

Task 56008195

Name HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_781_0
Workunit 26598537
Created 4 Jul 2024, 0:15:52 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 6 Jul 2024, 23:54:46 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 43 min 45 sec
CPU time 1 hours 5 min 49 sec
Validate state Valid
Credit 63.65
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 391.76 GB
Peak disk usage 0.26 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_781.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_781_0_r1933106999_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_781_0_r1933106999_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.996588
     * GNaL_b in INaL: 0.006228
     * Gto_b in Ito: 0.083104
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031761
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.164617
     * Gncx_b in INaCa_i: 0.000965
     * Pnak_b in INaK: 69.386597
     * GKb_b in IKb: 0.003780
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.028896
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19054043, states[0] = 9.339206, states[40]= 0.004941
Saving checkpoint... 
Iteration: 41715294, states[0] = -94.867420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 61771190, states[0] = -94.932614, states[40]= 0.000000
Saving checkpoint... 
Iteration: 80804870, states[0] = -94.955906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 100220126, states[0] = -94.852340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 122964842, states[0] = -95.010635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 141224869, states[0] = -94.856987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 156806527, states[0] = -94.949516, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178584685, states[0] = -5.307437, states[40]= 0.003342
Saving checkpoint... 
Iteration: 197490849, states[0] = -95.012203, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214113449, states[0] = -31.091807, states[40]= 0.000430
Saving checkpoint... 
Iteration: 232403159, states[0] = -94.994621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 253423491, states[0] = -94.999938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 276107220, states[0] = -25.254715, states[40]= 0.000711
Saving checkpoint... 
Iteration: 294144941, states[0] = -64.211635, states[40]= 0.000003
Saving checkpoint... 
Iteration: 317760091, states[0] = -94.905069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335256037, states[0] = -94.900194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357019738, states[0] = 21.557753, states[40]= 0.009941
Saving checkpoint... 
Iteration: 374119433, states[0] = -36.769312, states[40]= 0.000212
Saving checkpoint... 
Iteration: 396664406, states[0] = -92.221321, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415773239, states[0] = -94.919443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438899656, states[0] = -94.993356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 458424060, states[0] = -94.999889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 478403566, states[0] = -94.994481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 494680823, states[0] = -94.753789, states[40]= 0.000000
Saving checkpoint... 
Iteration: 513383827, states[0] = -94.988190, states[40]= 0.000000
Saving checkpoint... 
Iteration: 531504516, states[0] = 30.205004, states[40]= 0.154728
Saving checkpoint... 
Iteration: 552140863, states[0] = -59.360657, states[40]= 0.000006
Saving checkpoint... 
Iteration: 574205948, states[0] = -94.821024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595733516, states[0] = -94.869068, states[40]= 0.000000
Saving checkpoint... 
Iteration: 613190444, states[0] = -94.788774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631212396, states[0] = -94.833251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648850647, states[0] = -94.974544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 673437221, states[0] = -95.002709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 692440484, states[0] = -95.003376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 707083991, states[0] = -4.787952, states[40]= 0.003449
Saving checkpoint... 
Iteration: 728835860, states[0] = -94.966918, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743410406, states[0] = -94.996226, states[40]= 0.000000
Saving checkpoint... 
Iteration: 758506930, states[0] = 25.387446, states[40]= 0.107092
Saving checkpoint... 
Iteration: 778848380, states[0] = -94.973367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797839547, states[0] = -94.968864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818008514, states[0] = 24.117635, states[40]= 0.074987
Saving checkpoint... 
Iteration: 835739381, states[0] = -94.877655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854210345, states[0] = -94.829269, states[40]= 0.000000
Saving checkpoint... 
Iteration: 876632252, states[0] = -49.824140, states[40]= 0.000030
Saving checkpoint... 
Iteration: 896440641, states[0] = -95.003276, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913655260, states[0] = -79.320134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935133608, states[0] = -51.287910, states[40]= 0.000023
Saving checkpoint... 
Iteration: 957249484, states[0] = -94.891490, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977702900, states[0] = -94.814761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994905144, states[0] = -94.994599, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015374094, states[0] = -94.984319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1036691637, states[0] = -94.791223, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1050767305, states[0] = -94.912749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1072651701, states[0] = -73.472958, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1088554229, states[0] = 10.284943, states[40]= 0.004954
Saving checkpoint... 
Iteration: 1110359471, states[0] = -94.978277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1127553005, states[0] = 10.770962, states[40]= 0.004968
Saving checkpoint... 
Iteration: 1148179985, states[0] = -94.746860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1161241198, states[0] = -94.880051, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1180140680, states[0] = -59.149719, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1193953524, states[0] = -95.005569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216706141, states[0] = -94.820980, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237009353, states[0] = 23.706555, states[40]= 0.061557
Saving checkpoint... 
Iteration: 1256842533, states[0] = -94.970127, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271835147, states[0] = -94.966172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291355258, states[0] = -94.976277, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311140052, states[0] = -58.431377, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1329504862, states[0] = 29.145601, states[40]= 0.150815
Saving checkpoint... 
Iteration: 1346397598, states[0] = -94.992144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1367144194, states[0] = -63.292675, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1386979844, states[0] = -95.009679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1405992452, states[0] = -95.011351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1423321423, states[0] = -94.957946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444130850, states[0] = -48.324242, states[40]= 0.000038
Saving checkpoint... 
Iteration: 1462732544, states[0] = -94.867004, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1482420628, states[0] = -94.998392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1497649349, states[0] = -70.006684, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1515135513, states[0] = -80.589228, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529076088, states[0] = -95.242758, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1550459240, states[0] = 2.799815, states[40]= 0.005173
Saving checkpoint... 
Iteration: 1567135062, states[0] = -95.220285, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1585612381, states[0] = -50.855802, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1600830090, states[0] = 17.389081, states[40]= 0.007102
Saving checkpoint... 
Iteration: 1611656518, states[0] = 4.153950, states[40]= 0.005323
Saving checkpoint... 
Iteration: 1627213110, states[0] = 23.097875, states[40]= 0.028073
Saving checkpoint... 
Iteration: 1638046789, states[0] = 9.487702, states[40]= 0.005764
Saving checkpoint... 
Iteration: 1649349611, states[0] = -95.245568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1659432218, states[0] = -79.498377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1670907815, states[0] = -95.187698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1682568047, states[0] = -95.101703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1697939209, states[0] = -95.233948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1709412515, states[0] = 23.268975, states[40]= 0.031476
Saving checkpoint... 
Iteration: 1727916472, states[0] = -95.202259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1742850985, states[0] = -94.951686, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1752122254, states[0] = -63.713166, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1762466205, states[0] = -95.262654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1775288403, states[0] = -95.150344, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1785415563, states[0] = -55.084032, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1800940259, states[0] = -95.072230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813651142, states[0] = -78.151865, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824592528, states[0] = -13.471956, states[40]= 0.001719
Saving checkpoint... 
Iteration: 1835287756, states[0] = -94.956837, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1853045277, states[0] = 13.509839, states[40]= 0.005101
Saving checkpoint... 
Iteration: 1869277271, states[0] = -94.931547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885519123, states[0] = 21.627817, states[40]= 0.010528
Saving checkpoint... 
Iteration: 1906289409, states[0] = -94.936754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1927928673, states[0] = -95.001547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1947931856, states[0] = -95.001546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1970009540, states[0] = 23.627759, states[40]= 0.058900
Saving checkpoint... 
Iteration: 1993116469, states[0] = -33.948576, states[40]= 0.000307
Saving checkpoint... 
Iteration: 2017023400, states[0] = 20.757262, states[40]= 0.007675
Saving checkpoint... 
Iteration: 2034842974, states[0] = -94.969861, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2054883453, states[0] = -94.987041, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076898919, states[0] = -94.992034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092062914, states[0] = 6.665991, states[40]= 0.004828
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.887646
 - CaMKt in component CaMK (millimolar): 0.007069
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.621566
 - nass in component intracellular_ions (millimolar): 6.621626
 - ki in component intracellular_ions (millimolar): 145.354467
 - kss in component intracellular_ions (millimolar): 145.354448
 - cansr in component intracellular_ions (millimolar): 1.318735
 - cajsr in component intracellular_ions (millimolar): 1.280585
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003624
 - hf in component INa (dimensionless): 0.879754
 - hs in component INa (dimensionless): 0.879749
 - j in component INa (dimensionless): 0.879720
 - hsp in component INa (dimensionless): 0.725365
 - jp in component INa (dimensionless): 0.879701
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709260
 - hLp in component INaL (dimensionless): 0.450747
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619805
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694320
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933977
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.334805
 - xs1 in component IKs (dimensionless): 0.243846
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997341
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:54:34 (14047): called boinc_finish(0)

</stderr_txt>
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