𝕏

Task 56008112

Name HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_174_1
Workunit 26598495
Created 4 Jul 2024, 0:15:52 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 7 Jul 2024, 13:47:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 35 min 38 sec
CPU time 1 hours 2 min 4 sec
Validate state Valid
Credit 63.05
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 391.74 GB
Peak disk usage 0.25 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_174.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_174_1_r60531346_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_174_1_r60531346_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 100.158882
     * GNaL_b in INaL: 0.005794
     * Gto_b in Ito: 0.084512
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031557
     * GKs_b in IKs: 0.001971
     * GK1_b in IK1: 0.163258
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 70.291260
     * GKb_b in IKb: 0.003799
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029131
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15899132, states[0] = -95.049629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36709700, states[0] = -94.845453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 58989008, states[0] = -95.012721, states[40]= 0.000000
Saving checkpoint... 
Iteration: 81786964, states[0] = -94.923746, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104071459, states[0] = 2.397379, states[40]= 0.004520
Saving checkpoint... 
Iteration: 121555365, states[0] = 9.631859, states[40]= 0.004895
Saving checkpoint... 
Iteration: 143083162, states[0] = -4.455471, states[40]= 0.003503
Saving checkpoint... 
Iteration: 160773489, states[0] = -94.902433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 181730680, states[0] = -94.846091, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198574280, states[0] = 1.033608, states[40]= 0.004375
Saving checkpoint... 
Iteration: 219389329, states[0] = -94.973316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 237355780, states[0] = -94.959985, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255266817, states[0] = -94.894350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 271960377, states[0] = -94.990600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 292706425, states[0] = -94.802036, states[40]= 0.000000
Saving checkpoint... 
Iteration: 315300040, states[0] = -94.925715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 336564735, states[0] = 5.713832, states[40]= 0.004751
Saving checkpoint... 
Iteration: 355170519, states[0] = -94.273204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377338663, states[0] = -94.951216, states[40]= 0.000000
Saving checkpoint... 
Iteration: 399272652, states[0] = -94.900520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 418569590, states[0] = 3.444503, states[40]= 0.004605
Saving checkpoint... 
Iteration: 439447872, states[0] = -94.988159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461520944, states[0] = 21.112811, states[40]= 0.008750
Saving checkpoint... 
Iteration: 482241017, states[0] = -94.861201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 501366368, states[0] = -94.964362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 517375161, states[0] = -94.967871, states[40]= 0.000000
Saving checkpoint... 
Iteration: 536617554, states[0] = -35.244892, states[40]= 0.000258
Saving checkpoint... 
Iteration: 552682937, states[0] = -94.743341, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568791688, states[0] = -94.918596, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582182883, states[0] = -94.743044, states[40]= 0.000000
Saving checkpoint... 
Iteration: 599705081, states[0] = -94.799138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 616821075, states[0] = -94.940613, states[40]= 0.000000
Saving checkpoint... 
Iteration: 637498683, states[0] = -94.995883, states[40]= 0.000000
Saving checkpoint... 
Iteration: 655585865, states[0] = -6.374756, states[40]= 0.003105
Saving checkpoint... 
Iteration: 678143353, states[0] = -62.256869, states[40]= 0.000004
Saving checkpoint... 
Iteration: 699795599, states[0] = -94.921829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717869151, states[0] = -94.965362, states[40]= 0.000000
Saving checkpoint... 
Iteration: 740530370, states[0] = 18.698686, states[40]= 0.005929
Saving checkpoint... 
Iteration: 760869413, states[0] = -94.965440, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780931135, states[0] = -94.984406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 799415584, states[0] = -94.980589, states[40]= 0.000000
Saving checkpoint... 
Iteration: 818253306, states[0] = -94.877744, states[40]= 0.000000
Saving checkpoint... 
Iteration: 845962433, states[0] = -94.990533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 868420141, states[0] = -94.981715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 887332810, states[0] = -94.947593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 908117389, states[0] = -35.087557, states[40]= 0.000263
Saving checkpoint... 
Iteration: 928613811, states[0] = -31.703202, states[40]= 0.000399
Saving checkpoint... 
Iteration: 948228610, states[0] = -94.841737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 966979612, states[0] = -94.993144, states[40]= 0.000000
Saving checkpoint... 
Iteration: 990075282, states[0] = 0.493992, states[40]= 0.004310
Saving checkpoint... 
Iteration: 1011147612, states[0] = -67.510377, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1032786214, states[0] = -94.913406, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1051773386, states[0] = -94.900847, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1073405759, states[0] = -94.977701, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091971742, states[0] = -94.991881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1111118708, states[0] = -36.346688, states[40]= 0.000222
Saving checkpoint... 
Iteration: 1132858799, states[0] = -94.960663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1154037640, states[0] = 16.340325, states[40]= 0.005312
Saving checkpoint... 
Iteration: 1176003083, states[0] = 36.211080, states[40]= 0.145412
Saving checkpoint... 
Iteration: 1188852706, states[0] = -94.957813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207949297, states[0] = -94.987917, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1230821621, states[0] = -94.940551, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1250850348, states[0] = -94.956637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271275835, states[0] = -94.903222, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288642524, states[0] = -61.288753, states[40]= 0.000004
Saving checkpoint... 
Iteration: 1310670180, states[0] = -94.221825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330148502, states[0] = -68.687473, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1351478373, states[0] = -94.992706, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1371284169, states[0] = -94.911286, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1396939415, states[0] = -94.985803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415205152, states[0] = -94.798726, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439065707, states[0] = 5.274293, states[40]= 0.004727
Saving checkpoint... 
Iteration: 1462130021, states[0] = -47.649571, states[40]= 0.000042
Saving checkpoint... 
Iteration: 1483080221, states[0] = -2.435377, states[40]= 0.003878
Saving checkpoint... 
Iteration: 1505243817, states[0] = -91.728270, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1523169158, states[0] = -3.659134, states[40]= 0.004095
Saving checkpoint... 
Iteration: 1542424959, states[0] = -65.972048, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1563829043, states[0] = -95.195958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1581818816, states[0] = -95.185083, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1599751897, states[0] = -94.946967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617852321, states[0] = -95.232658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635205535, states[0] = -95.167099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1653539421, states[0] = -95.218801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1675964998, states[0] = -95.075200, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1696027815, states[0] = -71.831119, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1713186022, states[0] = -95.128491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727738726, states[0] = 13.353700, states[40]= 0.006118
Saving checkpoint... 
Iteration: 1742421899, states[0] = 20.287201, states[40]= 0.009427
Saving checkpoint... 
Iteration: 1759412403, states[0] = -95.179942, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1776392368, states[0] = -28.906870, states[40]= 0.000519
Saving checkpoint... 
Iteration: 1796367382, states[0] = -95.249165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815380303, states[0] = -95.011566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1837062353, states[0] = 6.275427, states[40]= 0.004798
Saving checkpoint... 
Iteration: 1858314990, states[0] = -94.948210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1884755339, states[0] = -94.885334, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1902210195, states[0] = -94.811696, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1918562900, states[0] = 6.483776, states[40]= 0.004789
Saving checkpoint... 
Iteration: 1943826828, states[0] = -94.944273, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968829961, states[0] = -94.945619, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1984348106, states[0] = -94.955284, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2006902197, states[0] = -94.976125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2028895275, states[0] = -94.973906, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2046982584, states[0] = -94.992829, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069358414, states[0] = -94.959824, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092907801, states[0] = -94.977549, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.870883
 - CaMKt in component CaMK (millimolar): 0.007098
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.593076
 - nass in component intracellular_ions (millimolar): 6.593136
 - ki in component intracellular_ions (millimolar): 145.382510
 - kss in component intracellular_ions (millimolar): 145.382491
 - cansr in component intracellular_ions (millimolar): 1.319529
 - cajsr in component intracellular_ions (millimolar): 1.281337
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003630
 - hf in component INa (dimensionless): 0.879462
 - hs in component INa (dimensionless): 0.879458
 - j in component INa (dimensionless): 0.879428
 - hsp in component INa (dimensionless): 0.724816
 - jp in component INa (dimensionless): 0.879408
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708763
 - hLp in component INaL (dimensionless): 0.450082
 - a in component Ito (dimensionless): 0.000625
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619762
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694343
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934648
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001632
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330931
 - xs1 in component IKs (dimensionless): 0.242965
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997345
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
22:47:45 (25780): called boinc_finish(0)

</stderr_txt>
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