𝕏

Task 56008104

Name HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_73_1
Workunit 26598491
Created 4 Jul 2024, 0:15:52 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 6 Jul 2024, 21:40:58 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 41 min 31 sec
CPU time 1 hours 4 min 37 sec
Validate state Valid
Credit 64.66
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.53 MB
Peak swap size 391.75 GB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_73.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_73_1_r164106081_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_73_1_r164106081_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.064012
     * GNaL_b in INaL: 0.005572
     * Gto_b in Ito: 0.082892
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031673
     * GKs_b in IKs: 0.001967
     * GK1_b in IK1: 0.167685
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.605926
     * GKb_b in IKb: 0.003822
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036318
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16734248, states[0] = -94.974740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36175614, states[0] = -94.818996, states[40]= 0.000000
Saving checkpoint... 
Iteration: 55840562, states[0] = -95.016547, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76814355, states[0] = -94.993217, states[40]= 0.000000
Saving checkpoint... 
Iteration: 97774485, states[0] = -94.957378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 119677089, states[0] = -94.786099, states[40]= 0.000000
Saving checkpoint... 
Iteration: 139571661, states[0] = 1.560584, states[40]= 0.004454
Saving checkpoint... 
Iteration: 161923835, states[0] = -95.027375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 178643293, states[0] = -65.574055, states[40]= 0.000002
Saving checkpoint... 
Iteration: 200879691, states[0] = -95.014484, states[40]= 0.000000
Saving checkpoint... 
Iteration: 222515900, states[0] = 21.951607, states[40]= 0.016269
Saving checkpoint... 
Iteration: 241773795, states[0] = -94.951379, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260013571, states[0] = 22.381182, states[40]= 0.024497
Saving checkpoint... 
Iteration: 280765358, states[0] = -94.942827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 301287853, states[0] = -94.963873, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323953352, states[0] = -95.032308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 339095850, states[0] = -16.632571, states[40]= 0.001266
Saving checkpoint... 
Iteration: 362999757, states[0] = -95.038731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 385108072, states[0] = -28.261380, states[40]= 0.000543
Saving checkpoint... 
Iteration: 401144630, states[0] = -67.272576, states[40]= 0.000001
Saving checkpoint... 
Iteration: 424211745, states[0] = -94.868158, states[40]= 0.000000
Saving checkpoint... 
Iteration: 442764249, states[0] = -94.941533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 461738606, states[0] = -94.910417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 481460995, states[0] = -95.033470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 504387623, states[0] = -95.016646, states[40]= 0.000000
Saving checkpoint... 
Iteration: 523504123, states[0] = 31.633711, states[40]= 0.150918
Saving checkpoint... 
Iteration: 541777933, states[0] = -94.955013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 561260713, states[0] = -94.937640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 583969062, states[0] = -95.034648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603377817, states[0] = -95.013336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 624691569, states[0] = -94.829291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640322550, states[0] = -94.988073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 661012446, states[0] = 22.607064, states[40]= 0.030782
Saving checkpoint... 
Iteration: 682173610, states[0] = -94.737518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704072349, states[0] = 1.237744, states[40]= 0.004417
Saving checkpoint... 
Iteration: 728037576, states[0] = 15.966379, states[40]= 0.005452
Saving checkpoint... 
Iteration: 746177454, states[0] = -94.784464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766932045, states[0] = -95.027987, states[40]= 0.000000
Saving checkpoint... 
Iteration: 787081885, states[0] = -4.651499, states[40]= 0.003475
Saving checkpoint... 
Iteration: 807836806, states[0] = -94.995816, states[40]= 0.000000
Saving checkpoint... 
Iteration: 829518590, states[0] = 21.438658, states[40]= 0.011404
Saving checkpoint... 
Iteration: 853170404, states[0] = -94.631279, states[40]= 0.000000
Saving checkpoint... 
Iteration: 871163175, states[0] = -93.266035, states[40]= 0.000000
Saving checkpoint... 
Iteration: 892966836, states[0] = -95.034125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913317634, states[0] = -94.984936, states[40]= 0.000000
Saving checkpoint... 
Iteration: 932337216, states[0] = -94.995950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 948747991, states[0] = -94.922455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 968443633, states[0] = -95.030161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 986018784, states[0] = 21.399419, states[40]= 0.011167
Saving checkpoint... 
Iteration: 1005702083, states[0] = -94.849965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1026261709, states[0] = -94.938443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043864803, states[0] = -95.008263, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1065379931, states[0] = -95.013779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1080412053, states[0] = -95.023201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102212574, states[0] = -94.869205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118101494, states[0] = -22.000032, states[40]= 0.000845
Saving checkpoint... 
Iteration: 1136385478, states[0] = -95.015573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1152960512, states[0] = -95.032981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1174850671, states[0] = -95.002249, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1197274460, states[0] = -94.951350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218844516, states[0] = -94.999376, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235926301, states[0] = -95.026466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1253249841, states[0] = -94.924564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1277923093, states[0] = -95.025722, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298477924, states[0] = -95.035469, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1318451542, states[0] = -95.031378, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336682573, states[0] = -94.807513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1358495382, states[0] = -95.037624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1381295716, states[0] = -94.969495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401290629, states[0] = -94.965464, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1420356642, states[0] = -95.004703, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436760367, states[0] = -94.936719, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457559755, states[0] = 7.247600, states[40]= 0.004857
Saving checkpoint... 
Iteration: 1473329356, states[0] = -94.991443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496017895, states[0] = 21.576714, states[40]= 0.012354
Saving checkpoint... 
Iteration: 1513474835, states[0] = -95.249111, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1528676211, states[0] = -95.124108, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1552762754, states[0] = -95.268515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1570326046, states[0] = -71.860302, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1589875956, states[0] = -95.147604, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606152825, states[0] = -95.269966, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1624551563, states[0] = 6.271837, states[40]= 0.005508
Saving checkpoint... 
Iteration: 1642901798, states[0] = -41.082010, states[40]= 0.000111
Saving checkpoint... 
Iteration: 1660369456, states[0] = -95.135731, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677113340, states[0] = -54.934583, states[40]= 0.000013
Saving checkpoint... 
Iteration: 1694243132, states[0] = -94.478512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1712646651, states[0] = -95.265806, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1732136005, states[0] = -95.253768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1749848052, states[0] = -95.267312, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769667368, states[0] = -95.285605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1786553338, states[0] = 5.231279, states[40]= 0.005418
Saving checkpoint... 
Iteration: 1809643114, states[0] = -70.388456, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1828368240, states[0] = -95.037765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1849609966, states[0] = -31.053027, states[40]= 0.000411
Saving checkpoint... 
Iteration: 1868069626, states[0] = 2.415649, states[40]= 0.004548
Saving checkpoint... 
Iteration: 1886729656, states[0] = -94.901881, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901210319, states[0] = -94.868113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1916777628, states[0] = -94.955997, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938193089, states[0] = -94.832725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959368446, states[0] = -95.009668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1976555260, states[0] = 9.137565, states[40]= 0.004932
Saving checkpoint... 
Iteration: 1996267106, states[0] = -94.943720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2014914546, states[0] = -95.023316, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2037063200, states[0] = 5.723420, states[40]= 0.004783
Saving checkpoint... 
Iteration: 2054255930, states[0] = -94.931314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2076078890, states[0] = -2.613605, states[40]= 0.003861
Saving checkpoint... 
Iteration: 2094975425, states[0] = -95.034595, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.913523
 - CaMKt in component CaMK (millimolar): 0.006883
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.603428
 - nass in component intracellular_ions (millimolar): 6.603488
 - ki in component intracellular_ions (millimolar): 145.375363
 - kss in component intracellular_ions (millimolar): 145.375343
 - cansr in component intracellular_ions (millimolar): 1.307438
 - cajsr in component intracellular_ions (millimolar): 1.269708
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003614
 - hf in component INa (dimensionless): 0.880203
 - hs in component INa (dimensionless): 0.880199
 - j in component INa (dimensionless): 0.880171
 - hsp in component INa (dimensionless): 0.726213
 - jp in component INa (dimensionless): 0.880153
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710632
 - hLp in component INaL (dimensionless): 0.453571
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622866
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698102
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936412
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999889
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001587
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330549
 - xs1 in component IKs (dimensionless): 0.238800
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997334
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:40:47 (12267): called boinc_finish(0)

</stderr_txt>
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