𝕏

Task 56008055

Name HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_958_0
Workunit 26598467
Created 4 Jul 2024, 0:15:47 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 7 Jul 2024, 8:14:35 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 36 min 19 sec
CPU time 1 hours 2 min 5 sec
Validate state Valid
Credit 64.75
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.42 MB
Peak swap size 391.75 GB
Peak disk usage 0.23 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_958.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_958_0_r1042010983_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_958_0_r1042010983_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 106.351503
     * GNaL_b in INaL: 0.005962
     * Gto_b in Ito: 0.081344
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032110
     * GKs_b in IKs: 0.001976
     * GK1_b in IK1: 0.163738
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 71.325099
     * GKb_b in IKb: 0.003818
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.032937
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19427149, states[0] = -95.078237, states[40]= 0.000000
Saving checkpoint... 
Iteration: 36381645, states[0] = -95.035278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 54570978, states[0] = 1.608844, states[40]= 0.004489
Saving checkpoint... 
Iteration: 68931003, states[0] = -95.024105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 85154725, states[0] = -84.013610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 101055680, states[0] = 9.093478, states[40]= 0.004954
Saving checkpoint... 
Iteration: 116808836, states[0] = -94.963470, states[40]= 0.000000
Saving checkpoint... 
Iteration: 134598742, states[0] = -19.186511, states[40]= 0.001027
Saving checkpoint... 
Iteration: 151625524, states[0] = -45.335927, states[40]= 0.000057
Saving checkpoint... 
Iteration: 169416417, states[0] = -95.007185, states[40]= 0.000000
Saving checkpoint... 
Iteration: 188100906, states[0] = -21.161712, states[40]= 0.000893
Saving checkpoint... 
Iteration: 200475401, states[0] = -95.018018, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215997028, states[0] = -95.020704, states[40]= 0.000000
Saving checkpoint... 
Iteration: 234478200, states[0] = -95.018212, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255427308, states[0] = -95.009050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 267766526, states[0] = -94.923337, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289450172, states[0] = -95.013621, states[40]= 0.000000
Saving checkpoint... 
Iteration: 309619642, states[0] = -39.219168, states[40]= 0.000143
Saving checkpoint... 
Iteration: 329021046, states[0] = 21.185717, states[40]= 0.009202
Saving checkpoint... 
Iteration: 345316368, states[0] = -94.964961, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365603181, states[0] = -23.308517, states[40]= 0.000780
Saving checkpoint... 
Iteration: 386643754, states[0] = -65.944968, states[40]= 0.000002
Saving checkpoint... 
Iteration: 405918404, states[0] = -95.006818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 424476002, states[0] = -95.017684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 444574946, states[0] = 0.029652, states[40]= 0.004279
Saving checkpoint... 
Iteration: 466249536, states[0] = -94.903389, states[40]= 0.000000
Saving checkpoint... 
Iteration: 489381692, states[0] = -94.996078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 508589456, states[0] = -10.421432, states[40]= 0.002260
Saving checkpoint... 
Iteration: 531229482, states[0] = -94.875156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549378462, states[0] = -94.994913, states[40]= 0.000000
Saving checkpoint... 
Iteration: 570856164, states[0] = -94.986093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 593020909, states[0] = 21.216975, states[40]= 0.009299
Saving checkpoint... 
Iteration: 612830866, states[0] = -94.973513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 632847832, states[0] = -94.982254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 652113292, states[0] = -32.993391, states[40]= 0.000330
Saving checkpoint... 
Iteration: 674314904, states[0] = -94.963808, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694648289, states[0] = -72.207430, states[40]= 0.000001
Saving checkpoint... 
Iteration: 715824608, states[0] = -94.969840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 737307652, states[0] = -94.958849, states[40]= 0.000000
Saving checkpoint... 
Iteration: 761803328, states[0] = -94.955727, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784258542, states[0] = -94.914114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802067436, states[0] = 3.965400, states[40]= 0.004683
Saving checkpoint... 
Iteration: 820861107, states[0] = -94.988059, states[40]= 0.000000
Saving checkpoint... 
Iteration: 842359651, states[0] = -94.987433, states[40]= 0.000000
Saving checkpoint... 
Iteration: 865026462, states[0] = 19.805052, states[40]= 0.006928
Saving checkpoint... 
Iteration: 888508726, states[0] = 24.179093, states[40]= 0.071154
Saving checkpoint... 
Iteration: 904473902, states[0] = -95.017093, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923603532, states[0] = -23.642873, states[40]= 0.000764
Saving checkpoint... 
Iteration: 942629087, states[0] = -49.055519, states[40]= 0.000032
Saving checkpoint... 
Iteration: 962922949, states[0] = -95.007569, states[40]= 0.000000
Saving checkpoint... 
Iteration: 981962051, states[0] = -95.015225, states[40]= 0.000000
Saving checkpoint... 
Iteration: 997767543, states[0] = -94.923935, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1015579982, states[0] = -3.074826, states[40]= 0.003786
Saving checkpoint... 
Iteration: 1030682653, states[0] = -94.783034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1047502914, states[0] = 38.418955, states[40]= 0.125685
Saving checkpoint... 
Iteration: 1070783111, states[0] = -94.939079, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1090849633, states[0] = -94.982826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114219786, states[0] = -94.859063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1128945978, states[0] = -95.012319, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151284692, states[0] = -94.940443, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172889631, states[0] = -94.998299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1194019796, states[0] = 21.463241, states[40]= 0.010214
Saving checkpoint... 
Iteration: 1212472167, states[0] = -95.016654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1232620327, states[0] = -39.904410, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1254110598, states[0] = -30.398397, states[40]= 0.000443
Saving checkpoint... 
Iteration: 1274437013, states[0] = -95.010466, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1291447620, states[0] = -95.012529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311220381, states[0] = -94.859951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1328331486, states[0] = -94.973428, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1347791740, states[0] = -94.946350, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359045491, states[0] = 13.261935, states[40]= 0.005146
Saving checkpoint... 
Iteration: 1381821134, states[0] = -94.967336, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1401840511, states[0] = -94.978189, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424188782, states[0] = -94.799001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1438321870, states[0] = -94.967754, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1455396997, states[0] = -95.000402, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1475930699, states[0] = -95.009010, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496015610, states[0] = 22.294875, states[40]= 0.017176
Saving checkpoint... 
Iteration: 1516415249, states[0] = -95.172375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1538619134, states[0] = -95.198104, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1556778845, states[0] = -14.849272, states[40]= 0.001680
Saving checkpoint... 
Iteration: 1577881774, states[0] = -95.144793, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1595683718, states[0] = -95.285224, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1616379422, states[0] = -95.283630, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1638603514, states[0] = 35.995770, states[40]= 0.116099
Saving checkpoint... 
Iteration: 1658923433, states[0] = -95.225495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678236046, states[0] = 14.449606, states[40]= 0.006480
Saving checkpoint... 
Iteration: 1702071169, states[0] = -95.125819, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722716103, states[0] = -58.190711, states[40]= 0.000008
Saving checkpoint... 
Iteration: 1744424940, states[0] = -95.227954, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1761388374, states[0] = -25.928075, states[40]= 0.000656
Saving checkpoint... 
Iteration: 1782657694, states[0] = 2.814400, states[40]= 0.005190
Saving checkpoint... 
Iteration: 1802957561, states[0] = -95.072715, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1820404296, states[0] = -95.039761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1838625688, states[0] = -47.000463, states[40]= 0.000044
Saving checkpoint... 
Iteration: 1857048937, states[0] = 11.704255, states[40]= 0.005069
Saving checkpoint... 
Iteration: 1877845883, states[0] = -94.987444, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1897415874, states[0] = -95.009103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1920116156, states[0] = -35.898931, states[40]= 0.000227
Saving checkpoint... 
Iteration: 1940262812, states[0] = -94.919301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962120820, states[0] = -40.438108, states[40]= 0.000120
Saving checkpoint... 
Iteration: 1979123379, states[0] = -43.036043, states[40]= 0.000081
Saving checkpoint... 
Iteration: 1998975100, states[0] = -95.016748, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2018315443, states[0] = -94.963407, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041601700, states[0] = -21.897748, states[40]= 0.000852
Saving checkpoint... 
Iteration: 2062790574, states[0] = -94.944929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2085302901, states[0] = -94.954578, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.895567
 - CaMKt in component CaMK (millimolar): 0.006858
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.562025
 - nass in component intracellular_ions (millimolar): 6.562084
 - ki in component intracellular_ions (millimolar): 145.417231
 - kss in component intracellular_ions (millimolar): 145.417211
 - cansr in component intracellular_ions (millimolar): 1.305950
 - cajsr in component intracellular_ions (millimolar): 1.268219
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003621
 - hf in component INa (dimensionless): 0.879892
 - hs in component INa (dimensionless): 0.879887
 - j in component INa (dimensionless): 0.879859
 - hsp in component INa (dimensionless): 0.725625
 - jp in component INa (dimensionless): 0.879840
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710080
 - hLp in component INaL (dimensionless): 0.452795
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.622457
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.697459
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935582
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999887
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001582
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.333317
 - xs1 in component IKs (dimensionless): 0.239943
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997339
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:14:22 (21239): called boinc_finish(0)

</stderr_txt>
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