𝕏

Task 56007989

Name HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_634_0
Workunit 26598434
Created 4 Jul 2024, 0:15:47 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 6 Jul 2024, 23:36:44 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 41 min 42 sec
CPU time 1 hours 5 min 42 sec
Validate state Valid
Credit 62.31
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 1.92 MB
Peak swap size 391.75 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_634.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_634_0_r1479545878_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_634_0_r1479545878_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 102.479567
     * GNaL_b in INaL: 0.005582
     * Gto_b in Ito: 0.081837
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032133
     * GKs_b in IKs: 0.001912
     * GK1_b in IK1: 0.165830
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 70.559543
     * GKb_b in IKb: 0.003808
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036799
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 19803280, states[0] = -95.037159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 42074377, states[0] = -0.878098, states[40]= 0.004166
Saving checkpoint... 
Iteration: 62080194, states[0] = -4.208067, states[40]= 0.003577
Saving checkpoint... 
Iteration: 83429334, states[0] = -95.032169, states[40]= 0.000000
Saving checkpoint... 
Iteration: 104281429, states[0] = -94.958431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 129575027, states[0] = -0.386773, states[40]= 0.004213
Saving checkpoint... 
Iteration: 148524801, states[0] = 20.066324, states[40]= 0.007304
Saving checkpoint... 
Iteration: 171572903, states[0] = 0.866921, states[40]= 0.004373
Saving checkpoint... 
Iteration: 194150643, states[0] = -77.312124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 215824389, states[0] = -94.984950, states[40]= 0.000000
Saving checkpoint... 
Iteration: 230386374, states[0] = -95.012033, states[40]= 0.000000
Saving checkpoint... 
Iteration: 255353197, states[0] = -94.999429, states[40]= 0.000000
Saving checkpoint... 
Iteration: 275275747, states[0] = -94.948327, states[40]= 0.000000
Saving checkpoint... 
Iteration: 294626963, states[0] = -47.587246, states[40]= 0.000040
Saving checkpoint... 
Iteration: 314971577, states[0] = -95.030768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 331683779, states[0] = -94.806124, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350418616, states[0] = -95.020796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369959635, states[0] = -95.028893, states[40]= 0.000000
Saving checkpoint... 
Iteration: 391901856, states[0] = -95.016453, states[40]= 0.000000
Saving checkpoint... 
Iteration: 411599522, states[0] = -20.412762, states[40]= 0.000934
Saving checkpoint... 
Iteration: 432440235, states[0] = -95.025401, states[40]= 0.000000
Saving checkpoint... 
Iteration: 448164072, states[0] = -93.779193, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469993306, states[0] = -95.033512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 488186531, states[0] = -94.812828, states[40]= 0.000000
Saving checkpoint... 
Iteration: 506492526, states[0] = -95.033397, states[40]= 0.000000
Saving checkpoint... 
Iteration: 525168575, states[0] = -94.534720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 544176730, states[0] = -94.775313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 564930117, states[0] = -95.023256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 582830999, states[0] = -94.988272, states[40]= 0.000000
Saving checkpoint... 
Iteration: 601630553, states[0] = -51.477789, states[40]= 0.000021
Saving checkpoint... 
Iteration: 623276365, states[0] = -94.948666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 647115581, states[0] = -35.928399, states[40]= 0.000223
Saving checkpoint... 
Iteration: 666852952, states[0] = -94.999013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 684318784, states[0] = -94.981129, states[40]= 0.000000
Saving checkpoint... 
Iteration: 702740819, states[0] = -94.908207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723985133, states[0] = -95.032354, states[40]= 0.000000
Saving checkpoint... 
Iteration: 742838782, states[0] = -94.992265, states[40]= 0.000000
Saving checkpoint... 
Iteration: 763844222, states[0] = -94.994934, states[40]= 0.000000
Saving checkpoint... 
Iteration: 785812335, states[0] = -94.976970, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804871670, states[0] = -95.006495, states[40]= 0.000000
Saving checkpoint... 
Iteration: 823308541, states[0] = -94.974412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839640886, states[0] = -63.309420, states[40]= 0.000003
Saving checkpoint... 
Iteration: 857564313, states[0] = 5.199603, states[40]= 0.004751
Saving checkpoint... 
Iteration: 879531411, states[0] = 18.127507, states[40]= 0.005997
Saving checkpoint... 
Iteration: 900448917, states[0] = -95.026737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 920933625, states[0] = -95.023776, states[40]= 0.000000
Saving checkpoint... 
Iteration: 941010098, states[0] = 23.332441, states[40]= 0.051398
Saving checkpoint... 
Iteration: 958407692, states[0] = -95.017685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978296441, states[0] = -94.965559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 998383952, states[0] = -95.010659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1017275388, states[0] = -94.947499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1035613521, states[0] = -33.911528, states[40]= 0.000291
Saving checkpoint... 
Iteration: 1052620974, states[0] = -41.319839, states[40]= 0.000104
Saving checkpoint... 
Iteration: 1073406344, states[0] = -95.017257, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1094452067, states[0] = -95.027175, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1118079376, states[0] = -3.021594, states[40]= 0.003788
Saving checkpoint... 
Iteration: 1138056088, states[0] = 8.808955, states[40]= 0.004918
Saving checkpoint... 
Iteration: 1158314826, states[0] = -94.978355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1178630507, states[0] = -51.426922, states[40]= 0.000021
Saving checkpoint... 
Iteration: 1199870696, states[0] = -95.005891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1218770395, states[0] = -94.942500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1236863463, states[0] = -95.003078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1255174681, states[0] = -94.754046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1274735567, states[0] = -94.900542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1294069908, states[0] = 2.477283, states[40]= 0.004544
Saving checkpoint... 
Iteration: 1313836990, states[0] = -94.991001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334277359, states[0] = -94.949162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1355683018, states[0] = -94.803385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376174712, states[0] = -94.754373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1394405374, states[0] = -95.016801, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1413829650, states[0] = -94.987022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1432610887, states[0] = -31.352212, states[40]= 0.000394
Saving checkpoint... 
Iteration: 1450816588, states[0] = -94.979293, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472784687, states[0] = -94.955663, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1493749940, states[0] = -94.919532, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511249048, states[0] = -94.829291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1533766815, states[0] = -95.103122, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551653123, states[0] = 5.632960, states[40]= 0.005435
Saving checkpoint... 
Iteration: 1572284695, states[0] = -95.291505, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1588144706, states[0] = -95.258738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1608363696, states[0] = -1.455953, states[40]= 0.004558
Saving checkpoint... 
Iteration: 1625995121, states[0] = -95.304392, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647446230, states[0] = -94.876799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1662295095, states[0] = -95.305207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677291965, states[0] = -95.303311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1694916864, states[0] = -95.226974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1713700419, states[0] = -39.960410, states[40]= 0.000129
Saving checkpoint... 
Iteration: 1732207628, states[0] = 25.668945, states[40]= 0.086149
Saving checkpoint... 
Iteration: 1752540105, states[0] = -95.257697, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1769980644, states[0] = -95.295526, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1787012522, states[0] = -95.220366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1803328636, states[0] = -95.040796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1815991353, states[0] = -95.073640, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829311184, states[0] = -95.004066, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1836146166, states[0] = -72.857373, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1848519087, states[0] = 21.285078, states[40]= 0.010708
Saving checkpoint... 
Iteration: 1856625690, states[0] = -47.154975, states[40]= 0.000043
Saving checkpoint... 
Iteration: 1871942823, states[0] = -95.033058, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1888259493, states[0] = -94.935563, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1901164754, states[0] = -94.032201, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1915653855, states[0] = -83.189120, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1922676927, states[0] = -94.778436, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1933807105, states[0] = -94.974009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945945041, states[0] = -95.026251, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1956742624, states[0] = -94.910488, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1968519945, states[0] = 21.247438, states[40]= 0.009933
Saving checkpoint... 
Iteration: 1985502764, states[0] = 38.926483, states[40]= 0.123257
Saving checkpoint... 
Iteration: 1995761393, states[0] = -94.932738, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2008008317, states[0] = 24.168375, states[40]= 0.077545
Saving checkpoint... 
Iteration: 2023066846, states[0] = 3.999369, states[40]= 0.004671
Saving checkpoint... 
Iteration: 2037631633, states[0] = -52.668856, states[40]= 0.000017
Saving checkpoint... 
Iteration: 2056878991, states[0] = -95.008323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2075737875, states[0] = -94.903278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2096568871, states[0] = 3.003841, states[40]= 0.004591
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.909114
 - CaMKt in component CaMK (millimolar): 0.006851
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.573340
 - nass in component intracellular_ions (millimolar): 6.573400
 - ki in component intracellular_ions (millimolar): 145.405925
 - kss in component intracellular_ions (millimolar): 145.405906
 - cansr in component intracellular_ions (millimolar): 1.305281
 - cajsr in component intracellular_ions (millimolar): 1.267611
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003616
 - hf in component INa (dimensionless): 0.880127
 - hs in component INa (dimensionless): 0.880122
 - j in component INa (dimensionless): 0.880095
 - hsp in component INa (dimensionless): 0.726069
 - jp in component INa (dimensionless): 0.880076
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.710645
 - hLp in component INaL (dimensionless): 0.453829
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623399
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698681
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.936426
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999890
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.329088
 - xs1 in component IKs (dimensionless): 0.238433
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997335
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
08:36:29 (13851): called boinc_finish(0)

</stderr_txt>
]]>