𝕏

Task 56007977

Name HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_132_0
Workunit 26598428
Created 4 Jul 2024, 0:15:47 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 7 Jul 2024, 4:43:34 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 39 min 27 sec
CPU time 1 hours 5 min 35 sec
Validate state Valid
Credit 65.10
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.63 MB
Peak swap size 391.75 GB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_132.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_132_0_r1315255213_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021541606973_ORdGradInc_k_26-Pueyo_APDR-conf_132_0_r1315255213_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 105.114106
     * GNaL_b in INaL: 0.005955
     * Gto_b in Ito: 0.086105
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031937
     * GKs_b in IKs: 0.001908
     * GK1_b in IK1: 0.166287
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 70.212065
     * GKb_b in IKb: 0.003813
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.029036
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 24513723, states[0] = 21.826426, states[40]= 0.023074
Saving checkpoint... 
Iteration: 47394923, states[0] = -95.034064, states[40]= 0.000000
Saving checkpoint... 
Iteration: 68420470, states[0] = -95.029795, states[40]= 0.000000
Saving checkpoint... 
Iteration: 89566647, states[0] = 4.546805, states[40]= 0.004693
Saving checkpoint... 
Iteration: 109655662, states[0] = -82.186141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 128960400, states[0] = -95.027451, states[40]= 0.000000
Saving checkpoint... 
Iteration: 143191752, states[0] = -94.812267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 159066259, states[0] = 4.866134, states[40]= 0.004708
Saving checkpoint... 
Iteration: 174738879, states[0] = -94.896570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 190392472, states[0] = -95.009620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 209066603, states[0] = 4.722205, states[40]= 0.004698
Saving checkpoint... 
Iteration: 229225128, states[0] = -94.874765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 250495199, states[0] = -95.030375, states[40]= 0.000000
Saving checkpoint... 
Iteration: 259005786, states[0] = 26.460428, states[40]= 0.135269
Saving checkpoint... 
Iteration: 277472098, states[0] = -95.027176, states[40]= 0.000000
Saving checkpoint... 
Iteration: 293645842, states[0] = -66.460423, states[40]= 0.000002
Saving checkpoint... 
Iteration: 310575075, states[0] = 0.440317, states[40]= 0.004308
Saving checkpoint... 
Iteration: 324933945, states[0] = -95.020165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340914968, states[0] = -95.015654, states[40]= 0.000000
Saving checkpoint... 
Iteration: 357481917, states[0] = -95.028522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 369638896, states[0] = -58.089596, states[40]= 0.000007
Saving checkpoint... 
Iteration: 390159656, states[0] = -88.290381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 408494319, states[0] = -95.030105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422891279, states[0] = -95.008742, states[40]= 0.000000
Saving checkpoint... 
Iteration: 439067810, states[0] = 4.159715, states[40]= 0.004661
Saving checkpoint... 
Iteration: 458476605, states[0] = -95.027699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 475982966, states[0] = -95.028585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 492044165, states[0] = 13.880117, states[40]= 0.005069
Saving checkpoint... 
Iteration: 508232381, states[0] = -94.886072, states[40]= 0.000000
Saving checkpoint... 
Iteration: 521582321, states[0] = -4.039000, states[40]= 0.003588
Saving checkpoint... 
Iteration: 536291495, states[0] = -94.954786, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547660226, states[0] = -89.067138, states[40]= 0.000000
Saving checkpoint... 
Iteration: 562740991, states[0] = -94.898785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 579120703, states[0] = -38.794774, states[40]= 0.000158
Saving checkpoint... 
Iteration: 592068062, states[0] = 4.039808, states[40]= 0.004653
Saving checkpoint... 
Iteration: 610502447, states[0] = 41.036479, states[40]= 0.116580
Saving checkpoint... 
Iteration: 628317669, states[0] = -94.974238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 640957565, states[0] = -95.024544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656655065, states[0] = -80.626107, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675176421, states[0] = -94.734730, states[40]= 0.000000
Saving checkpoint... 
Iteration: 694728598, states[0] = -94.879994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 709220349, states[0] = -94.866238, states[40]= 0.000000
Saving checkpoint... 
Iteration: 722965863, states[0] = -95.025878, states[40]= 0.000000
Saving checkpoint... 
Iteration: 735962349, states[0] = -95.025294, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749960065, states[0] = -95.024901, states[40]= 0.000000
Saving checkpoint... 
Iteration: 766314144, states[0] = -94.971804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 780314461, states[0] = -94.972009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 791973340, states[0] = -95.026994, states[40]= 0.000000
Saving checkpoint... 
Iteration: 804729828, states[0] = -94.881880, states[40]= 0.000000
Saving checkpoint... 
Iteration: 817289319, states[0] = -94.952733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 828106918, states[0] = -25.657462, states[40]= 0.000685
Saving checkpoint... 
Iteration: 848443157, states[0] = -95.021723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 867499460, states[0] = -95.030415, states[40]= 0.000000
Saving checkpoint... 
Iteration: 883289070, states[0] = -94.952473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 898867043, states[0] = -94.999647, states[40]= 0.000000
Saving checkpoint... 
Iteration: 916904741, states[0] = -95.012491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939949029, states[0] = -95.022798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 958996009, states[0] = -95.029943, states[40]= 0.000000
Saving checkpoint... 
Iteration: 975894451, states[0] = -95.009381, states[40]= 0.000000
Saving checkpoint... 
Iteration: 994996636, states[0] = -95.029995, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1013130654, states[0] = -49.015575, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1034695830, states[0] = -94.819031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1052080342, states[0] = -2.715421, states[40]= 0.003834
Saving checkpoint... 
Iteration: 1071370052, states[0] = -95.000734, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1091500143, states[0] = -77.464898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1113775547, states[0] = -94.939728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130431238, states[0] = -95.019027, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1151397264, states[0] = -95.010132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1170504495, states[0] = 29.711464, states[40]= 0.157821
Saving checkpoint... 
Iteration: 1187856235, states[0] = -94.994843, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1207811622, states[0] = -94.969783, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228860340, states[0] = -94.996623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1247813395, states[0] = -94.970974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1267227701, states[0] = -94.878166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1288111076, states[0] = -29.568679, states[40]= 0.000497
Saving checkpoint... 
Iteration: 1309677031, states[0] = -94.743295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1330724953, states[0] = -94.873623, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1349598711, states[0] = -17.955044, states[40]= 0.001134
Saving checkpoint... 
Iteration: 1369127798, states[0] = -45.989949, states[40]= 0.000054
Saving checkpoint... 
Iteration: 1393453941, states[0] = -95.023400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415933350, states[0] = -95.019301, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1437715264, states[0] = -94.856745, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1458764965, states[0] = -94.928358, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1481459735, states[0] = -95.024356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505984210, states[0] = -95.240765, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1522328560, states[0] = -71.043896, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1542302944, states[0] = 38.561410, states[40]= 0.108884
Saving checkpoint... 
Iteration: 1563958652, states[0] = 2.730007, states[40]= 0.005148
Saving checkpoint... 
Iteration: 1587074449, states[0] = -9.891739, states[40]= 0.002670
Saving checkpoint... 
Iteration: 1607670910, states[0] = -95.280141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1630490958, states[0] = -95.296858, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1651739832, states[0] = -95.249976, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1677231065, states[0] = -95.239113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1700929700, states[0] = -95.237383, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1722739142, states[0] = -91.881360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1740640877, states[0] = 12.184040, states[40]= 0.005996
Saving checkpoint... 
Iteration: 1759050709, states[0] = -94.991735, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780970630, states[0] = -95.124868, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1799661677, states[0] = -95.273879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1819532140, states[0] = 17.547448, states[40]= 0.005697
Saving checkpoint... 
Iteration: 1840622004, states[0] = -41.471955, states[40]= 0.000107
Saving checkpoint... 
Iteration: 1863292821, states[0] = -94.965603, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1885924701, states[0] = -95.022347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1905710370, states[0] = -94.850400, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1923957557, states[0] = -95.025373, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943416183, states[0] = -95.015817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1962750973, states[0] = -94.911818, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1983442977, states[0] = -95.021172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2003768412, states[0] = -94.931863, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2025207967, states[0] = -94.842764, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2047702839, states[0] = -94.832666, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2066655935, states[0] = -82.167125, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2090698464, states[0] = -94.823745, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.905482
 - CaMKt in component CaMK (millimolar): 0.007094
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.600370
 - nass in component intracellular_ions (millimolar): 6.600430
 - ki in component intracellular_ions (millimolar): 145.375190
 - kss in component intracellular_ions (millimolar): 145.375171
 - cansr in component intracellular_ions (millimolar): 1.319896
 - cajsr in component intracellular_ions (millimolar): 1.281759
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003617
 - hf in component INa (dimensionless): 0.880064
 - hs in component INa (dimensionless): 0.880059
 - j in component INa (dimensionless): 0.880030
 - hsp in component INa (dimensionless): 0.725949
 - jp in component INa (dimensionless): 0.880011
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709947
 - hLp in component INaL (dimensionless): 0.451929
 - a in component Ito (dimensionless): 0.000623
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.620863
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.695720
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935185
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999885
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001633
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.330988
 - xs1 in component IKs (dimensionless): 0.242040
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997336
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
13:43:19 (18248): called boinc_finish(0)

</stderr_txt>
]]>