𝕏

Task 56007904

Name HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_7_2
Workunit 26329935
Created 4 Jul 2024, 0:12:00 UTC
Sent 4 Jul 2024, 1:33:51 UTC
Report deadline 7 Jul 2024, 11:09:51 UTC
Received 4 Jul 2024, 4:02:36 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 241023
Run time 2 hours 27 min 39 sec
CPU time 2 hours 25 min 31 sec
Validate state Valid
Credit 59.94
Device peak FLOPS 1.00 GFLOPS
Application version Human ventricular cell models optimization v0.02
x86_64-pc-linux-gnu
Peak working set size 2.25 MB
Peak swap size 3.82 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_7.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_7_2_r1871598534_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240630151541569204_ORdGradInc_k_25-Pueyo_APDR-conf_7_2_r1871598534_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 115.012618
     * GNaL_b in INaL: 0.007246
     * Gto_b in Ito: 0.094051
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.030820
     * GKs_b in IKs: 0.002046
     * GK1_b in IK1: 0.160107
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 73.875987
     * GKb_b in IKb: 0.003762
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.047525
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 15100193, states[0] = -18.666043, states[40]= 0.001051
Saving checkpoint... 
Iteration: 30175544, states[0] = -94.685250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 45265563, states[0] = -95.004146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 60621042, states[0] = -34.035360, states[40]= 0.000309
Saving checkpoint... 
Iteration: 76010976, states[0] = 22.351798, states[40]= 0.043079
Saving checkpoint... 
Iteration: 91088705, states[0] = -5.222624, states[40]= 0.003261
Saving checkpoint... 
Iteration: 106306691, states[0] = -95.011478, states[40]= 0.000000
Saving checkpoint... 
Iteration: 121352195, states[0] = -95.036584, states[40]= 0.000000
Saving checkpoint... 
Iteration: 136589343, states[0] = -5.421286, states[40]= 0.003215
Saving checkpoint... 
Iteration: 151817243, states[0] = -95.014798, states[40]= 0.000000
Saving checkpoint... 
Iteration: 167063524, states[0] = 7.921967, states[40]= 0.004714
Saving checkpoint... 
Iteration: 182273075, states[0] = -94.976799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 197416835, states[0] = -95.056205, states[40]= 0.000000
Saving checkpoint... 
Iteration: 212868622, states[0] = -95.040474, states[40]= 0.000000
Saving checkpoint... 
Iteration: 228171294, states[0] = -92.461733, states[40]= 0.000000
Saving checkpoint... 
Iteration: 243354777, states[0] = -95.034351, states[40]= 0.000000
Saving checkpoint... 
Iteration: 258277212, states[0] = -94.980485, states[40]= 0.000000
Saving checkpoint... 
Iteration: 273813970, states[0] = -95.011153, states[40]= 0.000000
Saving checkpoint... 
Iteration: 289085002, states[0] = -2.476900, states[40]= 0.003764
Saving checkpoint... 
Iteration: 304444353, states[0] = -95.061991, states[40]= 0.000000
Saving checkpoint... 
Iteration: 319799265, states[0] = -95.000174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 335325220, states[0] = -95.018417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 350665139, states[0] = -85.208385, states[40]= 0.000000
Saving checkpoint... 
Iteration: 365650351, states[0] = -63.173526, states[40]= 0.000003
Saving checkpoint... 
Iteration: 380672549, states[0] = -93.154914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 395690074, states[0] = -94.837046, states[40]= 0.000000
Saving checkpoint... 
Iteration: 410299623, states[0] = -95.000394, states[40]= 0.000000
Saving checkpoint... 
Iteration: 425175777, states[0] = -94.176924, states[40]= 0.000000
Saving checkpoint... 
Iteration: 440127861, states[0] = -39.131666, states[40]= 0.000154
Saving checkpoint... 
Iteration: 454951163, states[0] = -95.063182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 469681855, states[0] = -94.728949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 484630350, states[0] = -41.547737, states[40]= 0.000108
Saving checkpoint... 
Iteration: 499128670, states[0] = -39.910000, states[40]= 0.000137
Saving checkpoint... 
Iteration: 513888774, states[0] = -95.047456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 528605896, states[0] = -19.155166, states[40]= 0.001024
Saving checkpoint... 
Iteration: 543383747, states[0] = -95.045724, states[40]= 0.000000
Saving checkpoint... 
Iteration: 558119459, states[0] = -31.327815, states[40]= 0.000428
Saving checkpoint... 
Iteration: 572770964, states[0] = -94.973761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 587254439, states[0] = -94.954499, states[40]= 0.000000
Saving checkpoint... 
Iteration: 602090675, states[0] = -6.291036, states[40]= 0.003034
Saving checkpoint... 
Iteration: 616783898, states[0] = -94.986675, states[40]= 0.000000
Saving checkpoint... 
Iteration: 631289717, states[0] = -94.991951, states[40]= 0.000000
Saving checkpoint... 
Iteration: 646110884, states[0] = -23.616519, states[40]= 0.000797
Saving checkpoint... 
Iteration: 660930668, states[0] = -95.058874, states[40]= 0.000000
Saving checkpoint... 
Iteration: 675847709, states[0] = -95.030618, states[40]= 0.000000
Saving checkpoint... 
Iteration: 690916753, states[0] = -95.055523, states[40]= 0.000000
Saving checkpoint... 
Iteration: 705797103, states[0] = -94.998173, states[40]= 0.000000
Saving checkpoint... 
Iteration: 720542383, states[0] = 15.611568, states[40]= 0.004981
Saving checkpoint... 
Iteration: 735255481, states[0] = -94.955718, states[40]= 0.000000
Saving checkpoint... 
Iteration: 750093152, states[0] = -8.166901, states[40]= 0.002641
Saving checkpoint... 
Iteration: 765251690, states[0] = -94.950855, states[40]= 0.000000
Saving checkpoint... 
Iteration: 779891866, states[0] = -95.048302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 794467006, states[0] = -95.065689, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809184116, states[0] = -94.783192, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824265912, states[0] = -94.968060, states[40]= 0.000000
Saving checkpoint... 
Iteration: 839336547, states[0] = -95.024692, states[40]= 0.000000
Saving checkpoint... 
Iteration: 854379336, states[0] = -95.043956, states[40]= 0.000000
Saving checkpoint... 
Iteration: 869363888, states[0] = -95.037887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 884283093, states[0] = -94.985750, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899145302, states[0] = -57.345354, states[40]= 0.000009
Saving checkpoint... 
Iteration: 913764527, states[0] = -94.966432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 928037938, states[0] = 17.043371, states[40]= 0.005170
Saving checkpoint... 
Iteration: 942336352, states[0] = -95.024520, states[40]= 0.000000
Saving checkpoint... 
Iteration: 956663760, states[0] = -82.885910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 970994560, states[0] = -95.069434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985374416, states[0] = -95.042040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 999985930, states[0] = -95.068315, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1014369296, states[0] = -95.040019, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1028897870, states[0] = -95.050031, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1043515662, states[0] = 21.914472, states[40]= 0.016676
Saving checkpoint... 
Iteration: 1057838027, states[0] = -95.025364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1071741495, states[0] = -94.936673, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1085780051, states[0] = -94.982708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1099765835, states[0] = -94.967799, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1114011402, states[0] = 22.369287, states[40]= 0.039123
Saving checkpoint... 
Iteration: 1128830904, states[0] = -95.021314, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1142986991, states[0] = -95.068366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1156864419, states[0] = -95.037929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1171485430, states[0] = -95.068141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1186182001, states[0] = -94.733130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1201209294, states[0] = -94.882527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1216236259, states[0] = -94.928827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231138968, states[0] = -50.422395, states[40]= 0.000027
Saving checkpoint... 
Iteration: 1245913804, states[0] = -95.054410, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1260896212, states[0] = -95.049374, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1276047678, states[0] = 13.811289, states[40]= 0.004861
Saving checkpoint... 
Iteration: 1290804922, states[0] = -95.003947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306103354, states[0] = -16.879325, states[40]= 0.001214
Saving checkpoint... 
Iteration: 1321342818, states[0] = -95.027737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1336515186, states[0] = 21.961526, states[40]= 0.018084
Saving checkpoint... 
Iteration: 1351654159, states[0] = -67.954728, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1366522600, states[0] = 20.960149, states[40]= 0.007844
Saving checkpoint... 
Iteration: 1381416074, states[0] = -95.054914, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1395965894, states[0] = -95.065132, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1410631298, states[0] = -42.484840, states[40]= 0.000094
Saving checkpoint... 
Iteration: 1425050054, states[0] = 12.978777, states[40]= 0.004831
Saving checkpoint... 
Iteration: 1440086328, states[0] = -3.309438, states[40]= 0.003620
Saving checkpoint... 
Iteration: 1455336534, states[0] = -95.024297, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1470679490, states[0] = -94.616899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1486049349, states[0] = 13.227210, states[40]= 0.004839
Saving checkpoint... 
Iteration: 1501327361, states[0] = -58.560556, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1516587555, states[0] = -17.296764, states[40]= 0.001294
Saving checkpoint... 
Iteration: 1531816611, states[0] = 22.067163, states[40]= 0.016140
Saving checkpoint... 
Iteration: 1547395454, states[0] = -95.338751, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1562606396, states[0] = -95.244178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577381301, states[0] = -95.339308, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592671804, states[0] = -95.334049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1607538775, states[0] = -82.902774, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1621663114, states[0] = -95.144853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1635540381, states[0] = -95.304481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649416140, states[0] = 21.944237, states[40]= 0.017077
Saving checkpoint... 
Iteration: 1663661148, states[0] = -95.131442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1678328805, states[0] = -66.588107, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1692313447, states[0] = 22.525314, states[40]= 0.026793
Saving checkpoint... 
Iteration: 1706244992, states[0] = -92.015929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1720493753, states[0] = -95.354635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1735516605, states[0] = 21.835710, states[40]= 0.015985
Saving checkpoint... 
Iteration: 1750674799, states[0] = -95.187188, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1765737148, states[0] = -95.301258, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780933424, states[0] = -73.638166, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1795503173, states[0] = 37.094214, states[40]= 0.108950
Saving checkpoint... 
Iteration: 1810321841, states[0] = -95.067573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1824819854, states[0] = -95.049859, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1839059628, states[0] = 9.027783, states[40]= 0.004763
Saving checkpoint... 
Iteration: 1853186958, states[0] = -94.838343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1867456788, states[0] = -95.073168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1881498551, states[0] = -95.075768, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895829022, states[0] = -95.023898, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1910111188, states[0] = -24.038684, states[40]= 0.000779
Saving checkpoint... 
Iteration: 1924281634, states[0] = -94.985459, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1938461487, states[0] = -95.065178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1952550637, states[0] = 12.760132, states[40]= 0.004825
Saving checkpoint... 
Iteration: 1966983661, states[0] = -95.067842, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1981254010, states[0] = -94.953345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995285517, states[0] = -94.987465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009547952, states[0] = 13.713947, states[40]= 0.004857
Saving checkpoint... 
Iteration: 2023624903, states[0] = -36.339227, states[40]= 0.000228
Saving checkpoint... 
Iteration: 2037592716, states[0] = -7.829666, states[40]= 0.002712
Saving checkpoint... 
Iteration: 2051574220, states[0] = 3.305053, states[40]= 0.004470
Saving checkpoint... 
Iteration: 2065475837, states[0] = -95.066207, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2079458966, states[0] = -95.063512, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2093195317, states[0] = -94.852816, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.945202
 - CaMKt in component CaMK (millimolar): 0.007063
 - cass in component intracellular_ions (millimolar): 0.000073
 - nai in component intracellular_ions (millimolar): 6.486361
 - nass in component intracellular_ions (millimolar): 6.486422
 - ki in component intracellular_ions (millimolar): 145.492372
 - kss in component intracellular_ions (millimolar): 145.492351
 - cansr in component intracellular_ions (millimolar): 1.307062
 - cajsr in component intracellular_ions (millimolar): 1.268141
 - cai in component intracellular_ions (millimolar): 0.000074
 - m in component INa (dimensionless): 0.003603
 - hf in component INa (dimensionless): 0.880751
 - hs in component INa (dimensionless): 0.880746
 - j in component INa (dimensionless): 0.880717
 - hsp in component INa (dimensionless): 0.727245
 - jp in component INa (dimensionless): 0.880698
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.709158
 - hLp in component INaL (dimensionless): 0.447711
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999871
 - iS in component Ito (dimensionless): 0.613505
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999871
 - iSp in component Ito (dimensionless): 0.686921
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.930019
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999865
 - jca in component ICaL (dimensionless): 0.999974
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001578
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.342124
 - xs1 in component IKs (dimensionless): 0.254703
 - xs2 in component IKs (dimensionless): 0.000087
 - xk1 in component IK1 (dimensionless): 0.997326
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
06:02:24 (648359): called boinc_finish(0)

</stderr_txt>
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