𝕏

Task 56007884

Name HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_782_1
Workunit 26598389
Created 4 Jul 2024, 0:11:05 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 7 Jul 2024, 3:35:06 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 40 min 37 sec
CPU time 1 hours 5 min 50 sec
Validate state Valid
Credit 63.06
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.52 MB
Peak swap size 391.75 GB
Peak disk usage 0.27 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_782.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_782_1_r483570113_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_782_1_r483570113_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.791519
     * GNaL_b in INaL: 0.005653
     * Gto_b in Ito: 0.086683
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031959
     * GKs_b in IKs: 0.001904
     * GK1_b in IK1: 0.163809
     * Gncx_b in INaCa_i: 0.000967
     * Pnak_b in INaK: 69.567848
     * GKb_b in IKb: 0.003800
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.036907
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 16739352, states[0] = -94.994187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 40914213, states[0] = -95.067836, states[40]= 0.000000
Saving checkpoint... 
Iteration: 63301504, states[0] = -95.001161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 84560606, states[0] = 7.012941, states[40]= 0.004798
Saving checkpoint... 
Iteration: 105804725, states[0] = -94.992347, states[40]= 0.000000
Saving checkpoint... 
Iteration: 127445690, states[0] = -95.046442, states[40]= 0.000000
Saving checkpoint... 
Iteration: 146746318, states[0] = -94.930945, states[40]= 0.000000
Saving checkpoint... 
Iteration: 171848398, states[0] = -95.014434, states[40]= 0.000000
Saving checkpoint... 
Iteration: 195319416, states[0] = -94.998164, states[40]= 0.000000
Saving checkpoint... 
Iteration: 214086770, states[0] = -7.763454, states[40]= 0.002799
Saving checkpoint... 
Iteration: 229870953, states[0] = -95.023534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249032368, states[0] = 17.791224, states[40]= 0.005720
Saving checkpoint... 
Iteration: 274135569, states[0] = -55.366756, states[40]= 0.000011
Saving checkpoint... 
Iteration: 294710792, states[0] = -94.873113, states[40]= 0.000000
Saving checkpoint... 
Iteration: 320433660, states[0] = -95.041561, states[40]= 0.000000
Saving checkpoint... 
Iteration: 340358399, states[0] = -95.018230, states[40]= 0.000000
Saving checkpoint... 
Iteration: 363938587, states[0] = -95.042554, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386223470, states[0] = -94.895377, states[40]= 0.000000
Saving checkpoint... 
Iteration: 409122332, states[0] = -41.276773, states[40]= 0.000107
Saving checkpoint... 
Iteration: 432475204, states[0] = -95.048833, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454654670, states[0] = -81.335432, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474305541, states[0] = -94.988262, states[40]= 0.000000
Saving checkpoint... 
Iteration: 495020432, states[0] = 20.916532, states[40]= 0.009213
Saving checkpoint... 
Iteration: 516572526, states[0] = 1.562337, states[40]= 0.004417
Saving checkpoint... 
Iteration: 540113065, states[0] = -32.195571, states[40]= 0.000366
Saving checkpoint... 
Iteration: 560965412, states[0] = -95.047264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581996393, states[0] = -95.051514, states[40]= 0.000000
Saving checkpoint... 
Iteration: 603710593, states[0] = -94.872521, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623012771, states[0] = 22.204573, states[40]= 0.028241
Saving checkpoint... 
Iteration: 643712312, states[0] = -94.875676, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664897584, states[0] = -95.032174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688810807, states[0] = -94.991841, states[40]= 0.000000
Saving checkpoint... 
Iteration: 708532815, states[0] = 17.650881, states[40]= 0.005676
Saving checkpoint... 
Iteration: 728153357, states[0] = -79.045747, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749683978, states[0] = -94.815040, states[40]= 0.000000
Saving checkpoint... 
Iteration: 768922073, states[0] = -95.038648, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783807065, states[0] = -94.989156, states[40]= 0.000000
Saving checkpoint... 
Iteration: 809869026, states[0] = -95.022291, states[40]= 0.000000
Saving checkpoint... 
Iteration: 832399773, states[0] = -95.032712, states[40]= 0.000000
Saving checkpoint... 
Iteration: 850131194, states[0] = -50.568193, states[40]= 0.000025
Saving checkpoint... 
Iteration: 862835138, states[0] = -95.006605, states[40]= 0.000000
Saving checkpoint... 
Iteration: 881755241, states[0] = -94.940417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 899900088, states[0] = -95.032760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 914990959, states[0] = -95.050637, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935068091, states[0] = 3.795856, states[40]= 0.004615
Saving checkpoint... 
Iteration: 956664917, states[0] = -93.453233, states[40]= 0.000000
Saving checkpoint... 
Iteration: 977965613, states[0] = -95.047024, states[40]= 0.000000
Saving checkpoint... 
Iteration: 987278165, states[0] = -94.965069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004396518, states[0] = -95.031632, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1018256142, states[0] = -94.941413, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033953418, states[0] = -95.044940, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1049523953, states[0] = 20.143208, states[40]= 0.007342
Saving checkpoint... 
Iteration: 1063651392, states[0] = -75.747172, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079413644, states[0] = -95.036360, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093031665, states[0] = 18.011568, states[40]= 0.005795
Saving checkpoint... 
Iteration: 1111259652, states[0] = -94.945487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1130371891, states[0] = -95.023187, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1147260258, states[0] = -94.946162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1168172760, states[0] = -94.677355, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1187840525, states[0] = -95.009235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1205989774, states[0] = -95.050298, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1220376465, states[0] = -95.024832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1235699436, states[0] = -94.850391, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1249655112, states[0] = -82.109080, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1266671739, states[0] = -94.630785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1279252211, states[0] = -94.936431, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1296423211, states[0] = -95.038573, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1309102186, states[0] = -21.840487, states[40]= 0.000854
Saving checkpoint... 
Iteration: 1324950638, states[0] = -95.044250, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1341361752, states[0] = -95.018999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1356323748, states[0] = -94.999760, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372146902, states[0] = -69.033902, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1385780066, states[0] = -94.966608, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1399936512, states[0] = -95.041449, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415121865, states[0] = -40.805073, states[40]= 0.000114
Saving checkpoint... 
Iteration: 1428955893, states[0] = -95.045117, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1443714139, states[0] = -94.878481, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1457668914, states[0] = -94.395199, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1469541730, states[0] = 14.593345, states[40]= 0.005127
Saving checkpoint... 
Iteration: 1486934109, states[0] = -95.040887, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1501084648, states[0] = -95.119159, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1513659517, states[0] = -95.071840, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1529347819, states[0] = -95.257655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1543038111, states[0] = -90.272655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1555898944, states[0] = -36.637409, states[40]= 0.000208
Saving checkpoint... 
Iteration: 1570193885, states[0] = -95.318529, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1586189951, states[0] = -27.195666, states[40]= 0.000592
Saving checkpoint... 
Iteration: 1598839490, states[0] = -92.551513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1611721974, states[0] = -65.445473, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1627093272, states[0] = -95.203492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1649011629, states[0] = -95.237487, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668243379, states[0] = -95.281546, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1686174873, states[0] = -95.163860, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1704871908, states[0] = -95.309879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1727484566, states[0] = -21.531589, states[40]= 0.000923
Saving checkpoint... 
Iteration: 1747010743, states[0] = -51.159438, states[40]= 0.000024
Saving checkpoint... 
Iteration: 1762920940, states[0] = -64.177790, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1786125869, states[0] = -95.259562, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1808710731, states[0] = -94.918587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1829301051, states[0] = -95.013831, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843851414, states[0] = -95.033591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1861034904, states[0] = 16.817614, states[40]= 0.005490
Saving checkpoint... 
Iteration: 1878750492, states[0] = -94.940919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1895723449, states[0] = -94.898635, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1913144518, states[0] = -66.114229, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1935147404, states[0] = -69.867254, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1959318307, states[0] = -94.996587, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1978407398, states[0] = -95.034438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1993834524, states[0] = -95.005717, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2015004887, states[0] = 28.293478, states[40]= 0.151350
Saving checkpoint... 
Iteration: 2031730574, states[0] = -94.905740, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050756862, states[0] = -94.941585, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2067834837, states[0] = -95.005625, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089039868, states[0] = 15.263572, states[40]= 0.005201
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.926772
 - CaMKt in component CaMK (millimolar): 0.007002
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.591792
 - nass in component intracellular_ions (millimolar): 6.591852
 - ki in component intracellular_ions (millimolar): 145.385381
 - kss in component intracellular_ions (millimolar): 145.385361
 - cansr in component intracellular_ions (millimolar): 1.313009
 - cajsr in component intracellular_ions (millimolar): 1.275018
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003609
 - hf in component INa (dimensionless): 0.880433
 - hs in component INa (dimensionless): 0.880428
 - j in component INa (dimensionless): 0.880400
 - hsp in component INa (dimensionless): 0.726645
 - jp in component INa (dimensionless): 0.880381
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.710686
 - hLp in component INaL (dimensionless): 0.453072
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.621879
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.696971
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.935991
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999888
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001604
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.328247
 - xs1 in component IKs (dimensionless): 0.240595
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997331
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
12:34:49 (17281): called boinc_finish(0)

</stderr_txt>
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