𝕏

Task 56007728

Name HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_359_1
Workunit 26598311
Created 4 Jul 2024, 0:11:00 UTC
Sent 4 Jul 2024, 1:33:43 UTC
Report deadline 7 Jul 2024, 11:09:43 UTC
Received 4 Jul 2024, 5:59:47 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 215734
Run time 2 hours 46 min 31 sec
CPU time 2 hours 40 min 9 sec
Validate state Valid
Credit 60.94
Device peak FLOPS 4.68 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.69 MB
Peak swap size 5.22 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_359.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_359_1_r348783366_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_359_1_r348783366_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 103.732678
     * GNaL_b in INaL: 0.005925
     * Gto_b in Ito: 0.085549
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031515
     * GKs_b in IKs: 0.001968
     * GK1_b in IK1: 0.160626
     * Gncx_b in INaCa_i: 0.000966
     * Pnak_b in INaK: 69.336158
     * GKb_b in IKb: 0.003834
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.033047
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 9963017, states[0] = -95.093967, states[40]= 0.000000
Saving checkpoint... 
Iteration: 23882242, states[0] = -95.037313, states[40]= 0.000000
Saving checkpoint... 
Iteration: 37896604, states[0] = -95.022198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 51839206, states[0] = -94.986657, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65590841, states[0] = -11.068121, states[40]= 0.002122
Saving checkpoint... 
Iteration: 79340766, states[0] = -94.975221, states[40]= 0.000000
Saving checkpoint... 
Iteration: 93185686, states[0] = -94.774645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107066860, states[0] = 4.633768, states[40]= 0.004682
Saving checkpoint... 
Iteration: 121058788, states[0] = 8.196085, states[40]= 0.004846
Saving checkpoint... 
Iteration: 135008852, states[0] = 23.470349, states[40]= 0.069198
Saving checkpoint... 
Iteration: 148888713, states[0] = -94.987290, states[40]= 0.000000
Saving checkpoint... 
Iteration: 162744314, states[0] = -94.880248, states[40]= 0.000000
Saving checkpoint... 
Iteration: 176594747, states[0] = -13.878460, states[40]= 0.001625
Saving checkpoint... 
Iteration: 190401077, states[0] = -94.990325, states[40]= 0.000000
Saving checkpoint... 
Iteration: 204085479, states[0] = -6.051550, states[40]= 0.003165
Saving checkpoint... 
Iteration: 218051997, states[0] = 10.969897, states[40]= 0.004927
Saving checkpoint... 
Iteration: 232080855, states[0] = -2.823177, states[40]= 0.003800
Saving checkpoint... 
Iteration: 246104770, states[0] = -23.161871, states[40]= 0.000800
Saving checkpoint... 
Iteration: 260148991, states[0] = -69.182291, states[40]= 0.000001
Saving checkpoint... 
Iteration: 274145762, states[0] = -65.028061, states[40]= 0.000002
Saving checkpoint... 
Iteration: 282725330, states[0] = -94.850089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 296417107, states[0] = -94.994369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 310178074, states[0] = -94.705827, states[40]= 0.000000
Saving checkpoint... 
Iteration: 323716016, states[0] = -94.833659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 337647299, states[0] = -66.954248, states[40]= 0.000002
Saving checkpoint... 
Iteration: 351526248, states[0] = 19.771678, states[40]= 0.006691
Saving checkpoint... 
Iteration: 365404163, states[0] = -94.990757, states[40]= 0.000000
Saving checkpoint... 
Iteration: 379226138, states[0] = -94.851359, states[40]= 0.000000
Saving checkpoint... 
Iteration: 393041398, states[0] = 14.946834, states[40]= 0.005154
Saving checkpoint... 
Iteration: 407025530, states[0] = 19.957090, states[40]= 0.006871
Saving checkpoint... 
Iteration: 419652214, states[0] = -73.785007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 433270257, states[0] = -94.911182, states[40]= 0.000000
Saving checkpoint... 
Iteration: 447171484, states[0] = -94.361105, states[40]= 0.000000
Saving checkpoint... 
Iteration: 460904540, states[0] = -94.990802, states[40]= 0.000000
Saving checkpoint... 
Iteration: 474600443, states[0] = -19.125923, states[40]= 0.001033
Saving checkpoint... 
Iteration: 488422836, states[0] = -94.995667, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502265082, states[0] = -94.905421, states[40]= 0.000000
Saving checkpoint... 
Iteration: 516170349, states[0] = -94.202157, states[40]= 0.000000
Saving checkpoint... 
Iteration: 530017222, states[0] = 21.704148, states[40]= 0.013030
Saving checkpoint... 
Iteration: 543903087, states[0] = -94.990323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 554812663, states[0] = -94.948150, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568125190, states[0] = -42.583503, states[40]= 0.000090
Saving checkpoint... 
Iteration: 581695319, states[0] = -94.792340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 595322944, states[0] = -94.954971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 606675420, states[0] = -94.636267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 620592474, states[0] = -11.803004, states[40]= 0.001976
Saving checkpoint... 
Iteration: 634434396, states[0] = -94.998254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 648322187, states[0] = -94.954455, states[40]= 0.000000
Saving checkpoint... 
Iteration: 662453129, states[0] = -95.002013, states[40]= 0.000000
Saving checkpoint... 
Iteration: 676513828, states[0] = 22.239574, states[40]= 0.022785
Saving checkpoint... 
Iteration: 690468109, states[0] = -95.004574, states[40]= 0.000000
Saving checkpoint... 
Iteration: 704258463, states[0] = -94.897522, states[40]= 0.000000
Saving checkpoint... 
Iteration: 718154861, states[0] = -77.991184, states[40]= 0.000000
Saving checkpoint... 
Iteration: 732202193, states[0] = -94.806638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 746084639, states[0] = -5.420105, states[40]= 0.003297
Saving checkpoint... 
Iteration: 759850290, states[0] = -94.970050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769481952, states[0] = -95.006602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 783309675, states[0] = -94.945875, states[40]= 0.000000
Saving checkpoint... 
Iteration: 797098525, states[0] = -17.338202, states[40]= 0.001188
Saving checkpoint... 
Iteration: 810847486, states[0] = -94.968638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 824557879, states[0] = 8.624605, states[40]= 0.004858
Saving checkpoint... 
Iteration: 838437559, states[0] = -94.998805, states[40]= 0.000000
Saving checkpoint... 
Iteration: 852119692, states[0] = -37.182744, states[40]= 0.000197
Saving checkpoint... 
Iteration: 866087305, states[0] = -7.447398, states[40]= 0.002866
Saving checkpoint... 
Iteration: 880065398, states[0] = 5.396945, states[40]= 0.004724
Saving checkpoint... 
Iteration: 894023665, states[0] = 20.414277, states[40]= 0.007465
Saving checkpoint... 
Iteration: 908041158, states[0] = 15.033167, states[40]= 0.005163
Saving checkpoint... 
Iteration: 921926080, states[0] = -94.996165, states[40]= 0.000000
Saving checkpoint... 
Iteration: 935756726, states[0] = -94.895243, states[40]= 0.000000
Saving checkpoint... 
Iteration: 949574882, states[0] = 0.720356, states[40]= 0.004327
Saving checkpoint... 
Iteration: 963502706, states[0] = 38.958520, states[40]= 0.126943
Saving checkpoint... 
Iteration: 977516246, states[0] = 21.863186, states[40]= 0.014979
Saving checkpoint... 
Iteration: 991428356, states[0] = -94.996655, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005326050, states[0] = -94.956638, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019174892, states[0] = -94.614728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1033072876, states[0] = 1.787904, states[40]= 0.004445
Saving checkpoint... 
Iteration: 1046710052, states[0] = -94.821979, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060625002, states[0] = -42.394387, states[40]= 0.000092
Saving checkpoint... 
Iteration: 1074401224, states[0] = -94.989422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1088303863, states[0] = -94.941357, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1102272812, states[0] = -94.913454, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1116118014, states[0] = -35.575245, states[40]= 0.000245
Saving checkpoint... 
Iteration: 1129761580, states[0] = -94.900965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1143557451, states[0] = 8.799918, states[40]= 0.004864
Saving checkpoint... 
Iteration: 1157150186, states[0] = -70.822565, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1170940303, states[0] = -94.999166, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1183250363, states[0] = -94.886958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1196762544, states[0] = -94.902049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1210579214, states[0] = -1.784505, states[40]= 0.003976
Saving checkpoint... 
Iteration: 1224353929, states[0] = -94.971480, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1237990481, states[0] = -95.007448, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1251757125, states[0] = -94.895527, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1265643921, states[0] = -62.805217, states[40]= 0.000003
Saving checkpoint... 
Iteration: 1279483229, states[0] = -95.006447, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1293243115, states[0] = -94.876971, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1306869966, states[0] = -94.978390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1320693951, states[0] = -94.788848, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1334778730, states[0] = -94.919318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1348634873, states[0] = -52.694952, states[40]= 0.000018
Saving checkpoint... 
Iteration: 1362465243, states[0] = -95.003668, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1376250279, states[0] = -94.886720, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1390441677, states[0] = -94.999306, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404422982, states[0] = -94.995103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1418099899, states[0] = -18.618098, states[40]= 0.001073
Saving checkpoint... 
Iteration: 1431683270, states[0] = -94.756296, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1445635195, states[0] = -53.041977, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1459517190, states[0] = 21.709650, states[40]= 0.013086
Saving checkpoint... 
Iteration: 1469017222, states[0] = 21.704321, states[40]= 0.013030
Saving checkpoint... 
Iteration: 1482846652, states[0] = -94.967780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1496574886, states[0] = 0.718347, states[40]= 0.004327
Saving checkpoint... 
Iteration: 1510225055, states[0] = 19.630156, states[40]= 0.008320
Saving checkpoint... 
Iteration: 1523995302, states[0] = -95.255559, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537739127, states[0] = -95.214920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551388822, states[0] = -24.366493, states[40]= 0.000752
Saving checkpoint... 
Iteration: 1565131965, states[0] = 16.451960, states[40]= 0.006753
Saving checkpoint... 
Iteration: 1578882318, states[0] = -95.274851, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1592633147, states[0] = -95.226412, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606221013, states[0] = 20.504262, states[40]= 0.010110
Saving checkpoint... 
Iteration: 1619984740, states[0] = -95.281259, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1633699187, states[0] = -95.174283, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1647364290, states[0] = -1.107321, states[40]= 0.004610
Saving checkpoint... 
Iteration: 1661013062, states[0] = -95.199910, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1674766104, states[0] = -95.097644, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1688560507, states[0] = -95.077500, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1702013634, states[0] = -52.966096, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1715922917, states[0] = -95.215803, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1729618150, states[0] = -58.536680, states[40]= 0.000007
Saving checkpoint... 
Iteration: 1739256922, states[0] = -95.054807, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1753048039, states[0] = -94.730241, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1766565487, states[0] = -95.095965, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1780405966, states[0] = -95.187919, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794170951, states[0] = -95.111324, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807898702, states[0] = -95.040988, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1821286990, states[0] = -94.964811, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1835044992, states[0] = 13.240081, states[40]= 0.005051
Saving checkpoint... 
Iteration: 1848922602, states[0] = -95.011889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858538815, states[0] = 15.685562, states[40]= 0.005265
Saving checkpoint... 
Iteration: 1872458329, states[0] = -95.010698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886400272, states[0] = -94.994255, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1900265693, states[0] = -94.908992, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1914011184, states[0] = 22.703285, states[40]= 0.040002
Saving checkpoint... 
Iteration: 1927609094, states[0] = -27.281209, states[40]= 0.000607
Saving checkpoint... 
Iteration: 1940760364, states[0] = -94.900115, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1954647730, states[0] = -67.579093, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1968114133, states[0] = -31.932105, states[40]= 0.000386
Saving checkpoint... 
Iteration: 1981977481, states[0] = -95.005456, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1995767145, states[0] = -94.906931, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2009589459, states[0] = -9.207417, states[40]= 0.002490
Saving checkpoint... 
Iteration: 2022998715, states[0] = -95.008007, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2036784295, states[0] = -94.924204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2050577479, states[0] = -0.745887, states[40]= 0.004134
Saving checkpoint... 
Iteration: 2064353759, states[0] = -94.970822, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2078163518, states[0] = -90.988049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2092003077, states[0] = 36.421986, states[40]= 0.140750
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883892
 - CaMKt in component CaMK (millimolar): 0.007046
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.608272
 - nass in component intracellular_ions (millimolar): 6.608332
 - ki in component intracellular_ions (millimolar): 145.368386
 - kss in component intracellular_ions (millimolar): 145.368367
 - cansr in component intracellular_ions (millimolar): 1.315440
 - cajsr in component intracellular_ions (millimolar): 1.277302
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879689
 - hs in component INa (dimensionless): 0.879684
 - j in component INa (dimensionless): 0.879654
 - hsp in component INa (dimensionless): 0.725242
 - jp in component INa (dimensionless): 0.879635
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709047
 - hLp in component INaL (dimensionless): 0.450279
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.619694
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.694279
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934791
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999883
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001614
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332053
 - xs1 in component IKs (dimensionless): 0.242998
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:58:41 (14500): called boinc_finish(0)

</stderr_txt>
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