𝕏

Task 56007674

Name HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_141_1
Workunit 26598284
Created 4 Jul 2024, 0:10:55 UTC
Sent 4 Jul 2024, 1:35:54 UTC
Report deadline 7 Jul 2024, 11:11:54 UTC
Received 7 Jul 2024, 5:04:45 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 232025
Run time 1 hours 40 min 26 sec
CPU time 1 hours 5 min 34 sec
Validate state Valid
Credit 65.09
Device peak FLOPS 5.03 GFLOPS
Application version Human ventricular cell models optimization v0.02
arm64-apple-darwin
Peak working set size 2.47 MB
Peak swap size 391.75 GB
Peak disk usage 0.24 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_141.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_141_1_r133716913_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704021051595857_ORdGradInc_k_26-Pueyo_APDR-conf_141_1_r133716913_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 104.509746
     * GNaL_b in INaL: 0.005465
     * Gto_b in Ito: 0.086167
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.032214
     * GKs_b in IKs: 0.001886
     * GK1_b in IK1: 0.164780
     * Gncx_b in INaCa_i: 0.000968
     * Pnak_b in INaK: 69.394258
     * GKb_b in IKb: 0.003821
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.035608
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 22043222, states[0] = 12.949195, states[40]= 0.005103
Saving checkpoint... 
Iteration: 41095459, states[0] = -18.154086, states[40]= 0.001111
Saving checkpoint... 
Iteration: 59722695, states[0] = -94.917318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 70318629, states[0] = -95.014050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 82473297, states[0] = -95.061009, states[40]= 0.000000
Saving checkpoint... 
Iteration: 95968118, states[0] = -95.057422, states[40]= 0.000000
Saving checkpoint... 
Iteration: 113520801, states[0] = 20.683992, states[40]= 0.009009
Saving checkpoint... 
Iteration: 128799490, states[0] = -94.990641, states[40]= 0.000000
Saving checkpoint... 
Iteration: 140962342, states[0] = -95.052278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 157108853, states[0] = -29.407875, states[40]= 0.000484
Saving checkpoint... 
Iteration: 170071099, states[0] = 1.823707, states[40]= 0.004454
Saving checkpoint... 
Iteration: 183540406, states[0] = 14.821348, states[40]= 0.005206
Saving checkpoint... 
Iteration: 205331538, states[0] = -95.009473, states[40]= 0.000000
Saving checkpoint... 
Iteration: 221327413, states[0] = -95.007045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 240201718, states[0] = -94.861813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 260571804, states[0] = 1.467574, states[40]= 0.004417
Saving checkpoint... 
Iteration: 280098507, states[0] = -19.410472, states[40]= 0.001003
Saving checkpoint... 
Iteration: 296924280, states[0] = -95.043268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 314028533, states[0] = 18.766666, states[40]= 0.006271
Saving checkpoint... 
Iteration: 328587035, states[0] = -8.797968, states[40]= 0.002585
Saving checkpoint... 
Iteration: 344758975, states[0] = -94.950198, states[40]= 0.000000
Saving checkpoint... 
Iteration: 354381297, states[0] = -95.031038, states[40]= 0.000000
Saving checkpoint... 
Iteration: 371443197, states[0] = -95.047204, states[40]= 0.000000
Saving checkpoint... 
Iteration: 386485177, states[0] = -95.053908, states[40]= 0.000000
Saving checkpoint... 
Iteration: 401267500, states[0] = -94.959533, states[40]= 0.000000
Saving checkpoint... 
Iteration: 415990039, states[0] = -95.054508, states[40]= 0.000000
Saving checkpoint... 
Iteration: 437137884, states[0] = -59.627733, states[40]= 0.000005
Saving checkpoint... 
Iteration: 453799418, states[0] = -94.988161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467136418, states[0] = -57.942386, states[40]= 0.000007
Saving checkpoint... 
Iteration: 486512058, states[0] = 22.283549, states[40]= 0.033068
Saving checkpoint... 
Iteration: 502670337, states[0] = -94.646853, states[40]= 0.000000
Saving checkpoint... 
Iteration: 512970431, states[0] = -95.051761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 526225060, states[0] = -94.903537, states[40]= 0.000000
Saving checkpoint... 
Iteration: 538254199, states[0] = -94.944445, states[40]= 0.000000
Saving checkpoint... 
Iteration: 549154446, states[0] = -83.663140, states[40]= 0.000000
Saving checkpoint... 
Iteration: 568981539, states[0] = -95.053307, states[40]= 0.000000
Saving checkpoint... 
Iteration: 581361480, states[0] = -95.023390, states[40]= 0.000000
Saving checkpoint... 
Iteration: 594973322, states[0] = -95.052136, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609355993, states[0] = -95.021034, states[40]= 0.000000
Saving checkpoint... 
Iteration: 623168552, states[0] = -94.530134, states[40]= 0.000000
Saving checkpoint... 
Iteration: 639266350, states[0] = -94.958162, states[40]= 0.000000
Saving checkpoint... 
Iteration: 656143048, states[0] = -65.899190, states[40]= 0.000002
Saving checkpoint... 
Iteration: 673089931, states[0] = -11.329600, states[40]= 0.002072
Saving checkpoint... 
Iteration: 688514812, states[0] = 21.806898, states[40]= 0.019099
Saving checkpoint... 
Iteration: 705788924, states[0] = -94.979580, states[40]= 0.000000
Saving checkpoint... 
Iteration: 723228607, states[0] = -94.909050, states[40]= 0.000000
Saving checkpoint... 
Iteration: 745303060, states[0] = -94.990694, states[40]= 0.000000
Saving checkpoint... 
Iteration: 767348971, states[0] = -95.017756, states[40]= 0.000000
Saving checkpoint... 
Iteration: 784196830, states[0] = -94.851542, states[40]= 0.000000
Saving checkpoint... 
Iteration: 802548663, states[0] = 11.714344, states[40]= 0.004973
Saving checkpoint... 
Iteration: 824901750, states[0] = -95.037137, states[40]= 0.000000
Saving checkpoint... 
Iteration: 843815392, states[0] = -94.999141, states[40]= 0.000000
Saving checkpoint... 
Iteration: 861055413, states[0] = 9.019060, states[40]= 0.004877
Saving checkpoint... 
Iteration: 884340790, states[0] = -95.013699, states[40]= 0.000000
Saving checkpoint... 
Iteration: 909793215, states[0] = -94.982999, states[40]= 0.000000
Saving checkpoint... 
Iteration: 923929111, states[0] = -95.043938, states[40]= 0.000000
Saving checkpoint... 
Iteration: 942144352, states[0] = -67.607574, states[40]= 0.000001
Saving checkpoint... 
Iteration: 966526148, states[0] = 19.432775, states[40]= 0.006755
Saving checkpoint... 
Iteration: 990283204, states[0] = -94.974417, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1004366289, states[0] = -95.025069, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1019059318, states[0] = 7.380027, states[40]= 0.004819
Saving checkpoint... 
Iteration: 1046165596, states[0] = -94.125620, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1066147157, states[0] = -71.539696, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1090809275, states[0] = -94.994891, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1112773079, states[0] = -94.964779, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1137075509, states[0] = -0.604626, states[40]= 0.004160
Saving checkpoint... 
Iteration: 1152215097, states[0] = -94.886242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1172516423, states[0] = 21.541845, states[40]= 0.014692
Saving checkpoint... 
Iteration: 1192963517, states[0] = -95.050254, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1214799954, states[0] = -94.988078, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1231676475, states[0] = -94.787103, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1252479338, states[0] = -95.052567, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1272147709, states[0] = -72.361838, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1292564893, states[0] = 4.896322, states[40]= 0.004699
Saving checkpoint... 
Iteration: 1315891679, states[0] = -95.033821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1335011435, states[0] = 22.414407, states[40]= 0.037975
Saving checkpoint... 
Iteration: 1353874447, states[0] = -95.027958, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1372534046, states[0] = 17.047643, states[40]= 0.005602
Saving checkpoint... 
Iteration: 1392960733, states[0] = -95.049674, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1415228742, states[0] = -94.908813, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1436022677, states[0] = 20.301555, states[40]= 0.007933
Saving checkpoint... 
Iteration: 1457035031, states[0] = 16.718146, states[40]= 0.005521
Saving checkpoint... 
Iteration: 1484188532, states[0] = -94.833408, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1505873993, states[0] = -95.117146, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1526384433, states[0] = -95.290268, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1548046638, states[0] = 9.102148, states[40]= 0.005686
Saving checkpoint... 
Iteration: 1565888579, states[0] = -95.189278, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1584879311, states[0] = -95.313062, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1606611403, states[0] = -53.174326, states[40]= 0.000017
Saving checkpoint... 
Iteration: 1625808507, states[0] = -49.688272, states[40]= 0.000030
Saving checkpoint... 
Iteration: 1650425073, states[0] = -71.999836, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1670741475, states[0] = 11.480670, states[40]= 0.005946
Saving checkpoint... 
Iteration: 1690920632, states[0] = -65.353056, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1708060254, states[0] = -95.128519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1730431131, states[0] = 16.313145, states[40]= 0.006870
Saving checkpoint... 
Iteration: 1751727477, states[0] = 17.827126, states[40]= 0.007513
Saving checkpoint... 
Iteration: 1771870113, states[0] = -7.036830, states[40]= 0.003343
Saving checkpoint... 
Iteration: 1790692376, states[0] = -95.327219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1807586056, states[0] = -10.894424, states[40]= 0.002219
Saving checkpoint... 
Iteration: 1826963664, states[0] = -95.081366, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1846793625, states[0] = -95.000552, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1871219398, states[0] = -94.902073, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1891633597, states[0] = -55.136528, states[40]= 0.000012
Saving checkpoint... 
Iteration: 1912071681, states[0] = 1.462077, states[40]= 0.004418
Saving checkpoint... 
Iteration: 1930394159, states[0] = -95.035659, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1945979884, states[0] = -95.053106, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1959559928, states[0] = 7.103901, states[40]= 0.004809
Saving checkpoint... 
Iteration: 1975295358, states[0] = -94.984387, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1992607282, states[0] = -27.849154, states[40]= 0.000558
Saving checkpoint... 
Iteration: 2004931587, states[0] = -95.043899, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2021380642, states[0] = -95.029788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2040995540, states[0] = -95.054135, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055361884, states[0] = -95.022592, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2069934153, states[0] = -95.044256, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084859240, states[0] = -95.021443, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.930440
 - CaMKt in component CaMK (millimolar): 0.006944
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.598272
 - nass in component intracellular_ions (millimolar): 6.598332
 - ki in component intracellular_ions (millimolar): 145.379562
 - kss in component intracellular_ions (millimolar): 145.379542
 - cansr in component intracellular_ions (millimolar): 1.310383
 - cajsr in component intracellular_ions (millimolar): 1.272589
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003608
 - hf in component INa (dimensionless): 0.880496
 - hs in component INa (dimensionless): 0.880491
 - j in component INa (dimensionless): 0.880463
 - hsp in component INa (dimensionless): 0.726765
 - jp in component INa (dimensionless): 0.880444
 - mL in component INaL (dimensionless): 0.000049
 - hL in component INaL (dimensionless): 0.711145
 - hLp in component INaL (dimensionless): 0.454279
 - a in component Ito (dimensionless): 0.000622
 - iF in component Ito (dimensionless): 0.999870
 - iS in component Ito (dimensionless): 0.623442
 - ap in component Ito (dimensionless): 0.000317
 - iFp in component Ito (dimensionless): 0.999870
 - iSp in component Ito (dimensionless): 0.698868
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.937062
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999891
 - jca in component ICaL (dimensionless): 0.999979
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001594
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.326616
 - xs1 in component IKs (dimensionless): 0.238135
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997330
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
14:04:31 (18507): called boinc_finish(0)

</stderr_txt>
]]>


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