𝕏

Task 56005771

Name HuVeMOp_20240704015554928756_ORdGradInc_k_26-Pueyo_APDR-conf_879_1
Workunit 26597360
Created 3 Jul 2024, 23:56:08 UTC
Sent 4 Jul 2024, 1:12:12 UTC
Report deadline 7 Jul 2024, 10:48:12 UTC
Received 4 Jul 2024, 9:33:48 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 238837
Run time 7 hours 43 min 37 sec
CPU time 1 hours 53 min 42 sec
Validate state Valid
Credit 64.40
Device peak FLOPS 3.47 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 10.63 MB
Peak swap size 6.24 MB
Peak disk usage 0.29 MB

Stderr output

<core_client_version>8.0.2</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704015554928756_ORdGradInc_k_26-Pueyo_APDR-conf_879.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704015554928756_ORdGradInc_k_26-Pueyo_APDR-conf_879_1_r413641288_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704015554928756_ORdGradInc_k_26-Pueyo_APDR-conf_879_1_r413641288_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 101.763289
     * GNaL_b in INaL: 0.005992
     * Gto_b in Ito: 0.085318
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031434
     * GKs_b in IKs: 0.001970
     * GK1_b in IK1: 0.163062
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 71.485086
     * GKb_b in IKb: 0.003794
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.030149
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 14446063, states[0] = -95.085130, states[40]= 0.000000
Saving checkpoint... 
Iteration: 29400224, states[0] = -95.038761, states[40]= 0.000000
Saving checkpoint... 
Iteration: 44406547, states[0] = -95.021489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 59935931, states[0] = -95.017183, states[40]= 0.000000
Saving checkpoint... 
Iteration: 76050924, states[0] = 11.414683, states[40]= 0.004936
Saving checkpoint... 
Iteration: 91841746, states[0] = -94.972796, states[40]= 0.000000
Saving checkpoint... 
Iteration: 107527294, states[0] = 19.597438, states[40]= 0.006439
Saving checkpoint... 
Iteration: 122600013, states[0] = -18.199717, states[40]= 0.001108
Saving checkpoint... 
Iteration: 138740582, states[0] = -94.875393, states[40]= 0.000000
Saving checkpoint... 
Iteration: 154781765, states[0] = -94.923593, states[40]= 0.000000
Saving checkpoint... 
Iteration: 170854863, states[0] = -94.972710, states[40]= 0.000000
Saving checkpoint... 
Iteration: 186538913, states[0] = 16.009614, states[40]= 0.005247
Saving checkpoint... 
Iteration: 202312860, states[0] = -94.948210, states[40]= 0.000000
Saving checkpoint... 
Iteration: 217997841, states[0] = -95.008643, states[40]= 0.000000
Saving checkpoint... 
Iteration: 233662533, states[0] = -89.192343, states[40]= 0.000000
Saving checkpoint... 
Iteration: 249027818, states[0] = 19.504316, states[40]= 0.006345
Saving checkpoint... 
Iteration: 265142698, states[0] = -60.401897, states[40]= 0.000005
Saving checkpoint... 
Iteration: 280642325, states[0] = -59.974021, states[40]= 0.000005
Saving checkpoint... 
Iteration: 296192875, states[0] = -94.786866, states[40]= 0.000000
Saving checkpoint... 
Iteration: 312105871, states[0] = -23.472977, states[40]= 0.000788
Saving checkpoint... 
Iteration: 327602242, states[0] = -20.109145, states[40]= 0.000965
Saving checkpoint... 
Iteration: 342952851, states[0] = -95.001602, states[40]= 0.000000
Saving checkpoint... 
Iteration: 358761219, states[0] = -94.900498, states[40]= 0.000000
Saving checkpoint... 
Iteration: 375100556, states[0] = -18.544261, states[40]= 0.001078
Saving checkpoint... 
Iteration: 390962484, states[0] = -95.003274, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406796865, states[0] = -94.935684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 422723756, states[0] = -94.846826, states[40]= 0.000000
Saving checkpoint... 
Iteration: 438233405, states[0] = -94.862570, states[40]= 0.000000
Saving checkpoint... 
Iteration: 454662532, states[0] = -89.180292, states[40]= 0.000000
Saving checkpoint... 
Iteration: 470488044, states[0] = -95.007065, states[40]= 0.000000
Saving checkpoint... 
Iteration: 486250847, states[0] = -94.887515, states[40]= 0.000000
Saving checkpoint... 
Iteration: 502107039, states[0] = -24.554033, states[40]= 0.000739
Saving checkpoint... 
Iteration: 517507534, states[0] = 24.357910, states[40]= 0.093543
Saving checkpoint... 
Iteration: 532401579, states[0] = -94.989302, states[40]= 0.000000
Saving checkpoint... 
Iteration: 547912414, states[0] = -94.992369, states[40]= 0.000000
Saving checkpoint... 
Iteration: 563162989, states[0] = -89.738001, states[40]= 0.000000
Saving checkpoint... 
Iteration: 578008936, states[0] = 23.505306, states[40]= 0.067519
Saving checkpoint... 
Iteration: 593716369, states[0] = -94.833681, states[40]= 0.000000
Saving checkpoint... 
Iteration: 609590801, states[0] = -9.748197, states[40]= 0.002372
Saving checkpoint... 
Iteration: 625362957, states[0] = -94.975339, states[40]= 0.000000
Saving checkpoint... 
Iteration: 641694953, states[0] = -94.791236, states[40]= 0.000000
Saving checkpoint... 
Iteration: 657378872, states[0] = -94.981665, states[40]= 0.000000
Saving checkpoint... 
Iteration: 672868296, states[0] = -94.977544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 688001630, states[0] = 47.086491, states[40]= 0.070268
Saving checkpoint... 
Iteration: 703627681, states[0] = -44.245073, states[40]= 0.000070
Saving checkpoint... 
Iteration: 719038849, states[0] = 16.037933, states[40]= 0.005250
Saving checkpoint... 
Iteration: 734459248, states[0] = -95.002492, states[40]= 0.000000
Saving checkpoint... 
Iteration: 749706754, states[0] = -94.815384, states[40]= 0.000000
Saving checkpoint... 
Iteration: 762651451, states[0] = -71.485699, states[40]= 0.000001
Saving checkpoint... 
Iteration: 778999774, states[0] = -95.008338, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795328551, states[0] = -94.957708, states[40]= 0.000000
Saving checkpoint... 
Iteration: 811509760, states[0] = 23.185438, states[40]= 0.055538
Saving checkpoint... 
Iteration: 822927317, states[0] = -94.995946, states[40]= 0.000000
Saving checkpoint... 
Iteration: 834582807, states[0] = -3.670953, states[40]= 0.003636
Saving checkpoint... 
Iteration: 849076232, states[0] = 0.330768, states[40]= 0.004270
Saving checkpoint... 
Iteration: 864440650, states[0] = -94.998864, states[40]= 0.000000
Saving checkpoint... 
Iteration: 879115363, states[0] = -32.300003, states[40]= 0.000372
Saving checkpoint... 
Iteration: 894004373, states[0] = 30.105737, states[40]= 0.156299
Saving checkpoint... 
Iteration: 909027380, states[0] = 19.624077, states[40]= 0.006429
Saving checkpoint... 
Iteration: 924728751, states[0] = -94.854830, states[40]= 0.000000
Saving checkpoint... 
Iteration: 940545816, states[0] = 13.532558, states[40]= 0.005016
Saving checkpoint... 
Iteration: 954786039, states[0] = -94.925944, states[40]= 0.000000
Saving checkpoint... 
Iteration: 969831549, states[0] = -94.959364, states[40]= 0.000000
Saving checkpoint... 
Iteration: 985777064, states[0] = -94.917326, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1002037108, states[0] = 16.634309, states[40]= 0.005345
Saving checkpoint... 
Iteration: 1017627567, states[0] = -44.128930, states[40]= 0.000071
Saving checkpoint... 
Iteration: 1034152450, states[0] = -72.954596, states[40]= 0.000001
Saving checkpoint... 
Iteration: 1048906583, states[0] = -94.990425, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1064260633, states[0] = -94.899340, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1079280640, states[0] = -94.920785, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1093691263, states[0] = -94.782565, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1106822684, states[0] = -94.953889, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1122725628, states[0] = -94.849534, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1139084552, states[0] = -4.875731, states[40]= 0.003400
Saving checkpoint... 
Iteration: 1155647897, states[0] = -66.662806, states[40]= 0.000002
Saving checkpoint... 
Iteration: 1172141865, states[0] = -59.447905, states[40]= 0.000006
Saving checkpoint... 
Iteration: 1186310002, states[0] = -94.945267, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202599917, states[0] = -17.950945, states[40]= 0.001129
Saving checkpoint... 
Iteration: 1217618389, states[0] = -35.151425, states[40]= 0.000260
Saving checkpoint... 
Iteration: 1233529646, states[0] = 18.990788, states[40]= 0.006049
Saving checkpoint... 
Iteration: 1249186607, states[0] = -94.769560, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1264853740, states[0] = -94.970781, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1280577046, states[0] = -0.124660, states[40]= 0.004211
Saving checkpoint... 
Iteration: 1296084092, states[0] = -4.551506, states[40]= 0.003465
Saving checkpoint... 
Iteration: 1312056936, states[0] = 9.250072, states[40]= 0.004866
Saving checkpoint... 
Iteration: 1327842739, states[0] = -94.965295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1343319374, states[0] = -94.951600, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1359580223, states[0] = -2.004321, states[40]= 0.003931
Saving checkpoint... 
Iteration: 1375810680, states[0] = -94.945629, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1392137240, states[0] = -54.325552, states[40]= 0.000014
Saving checkpoint... 
Iteration: 1408745309, states[0] = -94.879446, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1424257601, states[0] = -94.895452, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1439863242, states[0] = -94.974929, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1456346121, states[0] = -94.966947, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1472675595, states[0] = -94.624788, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1488365750, states[0] = -94.975959, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1504857155, states[0] = 5.110312, states[40]= 0.005213
Saving checkpoint... 
Iteration: 1520850973, states[0] = -94.711208, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1536195384, states[0] = -95.138502, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1551113547, states[0] = -51.023179, states[40]= 0.000025
Saving checkpoint... 
Iteration: 1565479203, states[0] = -13.679682, states[40]= 0.001870
Saving checkpoint... 
Iteration: 1578139949, states[0] = -90.433981, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590714435, states[0] = -52.781468, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1605543627, states[0] = -95.235209, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1620768054, states[0] = -95.096540, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1636862687, states[0] = 0.367408, states[40]= 0.004834
Saving checkpoint... 
Iteration: 1652902093, states[0] = -95.174556, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1668696107, states[0] = -32.219039, states[40]= 0.000367
Saving checkpoint... 
Iteration: 1683205707, states[0] = -95.181518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1698652534, states[0] = 6.453349, states[40]= 0.005466
Saving checkpoint... 
Iteration: 1714951263, states[0] = -94.921752, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1731036180, states[0] = 14.642310, states[40]= 0.006306
Saving checkpoint... 
Iteration: 1747141161, states[0] = -95.234571, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1762872153, states[0] = -7.074708, states[40]= 0.003327
Saving checkpoint... 
Iteration: 1778892192, states[0] = -95.155345, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1794935170, states[0] = 15.099291, states[40]= 0.006393
Saving checkpoint... 
Iteration: 1811090002, states[0] = -11.669238, states[40]= 0.002044
Saving checkpoint... 
Iteration: 1826899921, states[0] = -95.019395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1842701420, states[0] = -94.824022, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1858711358, states[0] = -94.836049, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1873207749, states[0] = -94.824684, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1887990051, states[0] = -95.011477, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1904119950, states[0] = -36.832929, states[40]= 0.000207
Saving checkpoint... 
Iteration: 1919166548, states[0] = -92.856743, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1934107743, states[0] = -25.280168, states[40]= 0.000705
Saving checkpoint... 
Iteration: 1949863885, states[0] = -94.975633, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1965033261, states[0] = 17.888563, states[40]= 0.005633
Saving checkpoint... 
Iteration: 1980023810, states[0] = 20.520144, states[40]= 0.007390
Saving checkpoint... 
Iteration: 1996075897, states[0] = 0.509867, states[40]= 0.004292
Saving checkpoint... 
Iteration: 2012378097, states[0] = -94.980564, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2027707598, states[0] = -94.816219, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041229628, states[0] = -94.855518, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2057378799, states[0] = -94.980700, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2073221440, states[0] = -94.841709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2089286974, states[0] = -94.926008, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.883332
 - CaMKt in component CaMK (millimolar): 0.007044
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.557435
 - nass in component intracellular_ions (millimolar): 6.557495
 - ki in component intracellular_ions (millimolar): 145.419463
 - kss in component intracellular_ions (millimolar): 145.419444
 - cansr in component intracellular_ions (millimolar): 1.314434
 - cajsr in component intracellular_ions (millimolar): 1.276189
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003625
 - hf in component INa (dimensionless): 0.879679
 - hs in component INa (dimensionless): 0.879674
 - j in component INa (dimensionless): 0.879645
 - hsp in component INa (dimensionless): 0.725224
 - jp in component INa (dimensionless): 0.879625
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.708864
 - hLp in component INaL (dimensionless): 0.449778
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.618830
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.693221
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.933970
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999881
 - jca in component ICaL (dimensionless): 0.999977
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001611
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.332762
 - xs1 in component IKs (dimensionless): 0.244708
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997342
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
17:56:29 (625004): called boinc_finish(0)

</stderr_txt>
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