𝕏

Task 56005421

Name HuVeMOp_20240704015542488366_ORdGradInc_k_26-Pueyo_APDR-conf_880_0
Workunit 26597186
Created 3 Jul 2024, 23:55:53 UTC
Sent 4 Jul 2024, 1:12:13 UTC
Report deadline 7 Jul 2024, 10:48:13 UTC
Received 4 Jul 2024, 9:45:12 UTC
Server state Over
Outcome Success
Client state Done
Exit status 0 (0x00000000)
Computer ID 236853
Run time 2 hours 48 min 53 sec
CPU time 2 hours 48 min 45 sec
Validate state Valid
Credit 62.58
Device peak FLOPS 3.54 GFLOPS
Application version Human ventricular cell models optimization v0.02
windows_x86_64
Peak working set size 4.39 MB
Peak swap size 2.53 MB
Peak disk usage 0.28 MB

Stderr output

<core_client_version>7.24.1</core_client_version>
<![CDATA[
<stderr_txt>


===============================================================

                --- DENIS Myocyte Simulator ---                
                      Version 0.22 - Beta                      

---------------------------------------------------------------
                                          https://denis.usj.es 
                                         Universidad San Jorge 
===============================================================

Boinc file names: 
 - INPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704015542488366_ORdGradInc_k_26-Pueyo_APDR-conf_880.xml
 - OUTPUT_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704015542488366_ORdGradInc_k_26-Pueyo_APDR-conf_880_0_r2112858579_0
 - MARKERS_FILENAME: ../../projects/denis.usj.es_denisathome/HuVeMOp_20240704015542488366_ORdGradInc_k_26-Pueyo_APDR-conf_880_0_r2112858579_1
 - CHECKPOINT_FILE: denis_checkpoint
 - CHECKPOINT_FILE_2: denis_checkpoint_2


Configuration:
 - Model name: ORd_SS_biphasic
 - Solver: FE
 - Simulation time: 4200000.000000
 - dt: 0.002000
 - Constants to change: 21
     * GNa in INa: 107.099697
     * GNaL_b in INaL: 0.005993
     * Gto_b in Ito: 0.082389
     * PCa_b in ICaL: 0.000080
     * GKr_b in IKr: 0.031490
     * GKs_b in IKs: 0.001921
     * GK1_b in IK1: 0.161873
     * Gncx_b in INaCa_i: 0.000969
     * Pnak_b in INaK: 69.335801
     * GKb_b in IKb: 0.003831
     * PNab in INab: 0.000000
     * PCab in ICab: 0.000000
     * GpCa in IpCa: 0.037365
     * celltype in environment: 0.000000
     * nCL_1 in membrane: 1000.000000
     * CL_1 in membrane: 600.000000
     * nCL_2 in membrane: 600.000000
     * CL_2 in membrane: 1000.000000
     * cao in extracellular: 1.000000
     * ko in extracellular: 4.000000
     * nao in extracellular: 144.000000
Starting output configuration...
No Output to save.
Saving checkpoint... 
Iteration: 13198901, states[0] = -94.887591, states[40]= 0.000000
Saving checkpoint... 
Iteration: 26288321, states[0] = -94.974705, states[40]= 0.000000
Saving checkpoint... 
Iteration: 39370539, states[0] = -95.005519, states[40]= 0.000000
Saving checkpoint... 
Iteration: 52459458, states[0] = -95.018180, states[40]= 0.000000
Saving checkpoint... 
Iteration: 65645820, states[0] = -67.439786, states[40]= 0.000001
Saving checkpoint... 
Iteration: 78729288, states[0] = -94.865232, states[40]= 0.000000
Saving checkpoint... 
Iteration: 91911171, states[0] = -94.993395, states[40]= 0.000000
Saving checkpoint... 
Iteration: 105111976, states[0] = -30.674781, states[40]= 0.000437
Saving checkpoint... 
Iteration: 118509688, states[0] = 23.591232, states[40]= 0.057090
Saving checkpoint... 
Iteration: 131708993, states[0] = -94.822479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 144908306, states[0] = -94.987479, states[40]= 0.000000
Saving checkpoint... 
Iteration: 158076353, states[0] = -0.350294, states[40]= 0.004209
Saving checkpoint... 
Iteration: 158932104, states[0] = -94.992777, states[40]= 0.000000
Saving checkpoint... 
Iteration: 172089017, states[0] = -9.225275, states[40]= 0.002495
Saving checkpoint... 
Iteration: 185489864, states[0] = -95.001922, states[40]= 0.000000
Saving checkpoint... 
Iteration: 198679454, states[0] = -94.738063, states[40]= 0.000000
Saving checkpoint... 
Iteration: 211862296, states[0] = -94.970698, states[40]= 0.000000
Saving checkpoint... 
Iteration: 225047545, states[0] = 12.617420, states[40]= 0.005070
Saving checkpoint... 
Iteration: 238237314, states[0] = -94.867525, states[40]= 0.000000
Saving checkpoint... 
Iteration: 251433443, states[0] = -94.992161, states[40]= 0.000000
Saving checkpoint... 
Iteration: 264617450, states[0] = -35.615975, states[40]= 0.000240
Saving checkpoint... 
Iteration: 277812295, states[0] = -94.943658, states[40]= 0.000000
Saving checkpoint... 
Iteration: 291000693, states[0] = 42.466802, states[40]= 0.006239
Saving checkpoint... 
Iteration: 304409114, states[0] = -94.986242, states[40]= 0.000000
Saving checkpoint... 
Iteration: 317594921, states[0] = -14.432893, states[40]= 0.001546
Saving checkpoint... 
Iteration: 332434672, states[0] = -94.992318, states[40]= 0.000000
Saving checkpoint... 
Iteration: 347256104, states[0] = -94.892235, states[40]= 0.000000
Saving checkpoint... 
Iteration: 362184749, states[0] = -94.767311, states[40]= 0.000000
Saving checkpoint... 
Iteration: 377011870, states[0] = 22.962280, states[40]= 0.034893
Saving checkpoint... 
Iteration: 391837335, states[0] = -94.958624, states[40]= 0.000000
Saving checkpoint... 
Iteration: 406668341, states[0] = -94.013077, states[40]= 0.000000
Saving checkpoint... 
Iteration: 420782069, states[0] = -94.919568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 428026593, states[0] = 19.793098, states[40]= 0.006844
Saving checkpoint... 
Iteration: 441062135, states[0] = 6.694385, states[40]= 0.004827
Saving checkpoint... 
Iteration: 454194390, states[0] = -94.791356, states[40]= 0.000000
Saving checkpoint... 
Iteration: 467328715, states[0] = -94.953804, states[40]= 0.000000
Saving checkpoint... 
Iteration: 480431513, states[0] = -94.991544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 493538208, states[0] = 16.080404, states[40]= 0.005420
Saving checkpoint... 
Iteration: 506900707, states[0] = -94.983759, states[40]= 0.000000
Saving checkpoint... 
Iteration: 520055300, states[0] = 9.564409, states[40]= 0.004941
Saving checkpoint... 
Iteration: 533199093, states[0] = -94.800955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 546330420, states[0] = -94.954732, states[40]= 0.000000
Saving checkpoint... 
Iteration: 559436547, states[0] = -94.992566, states[40]= 0.000000
Saving checkpoint... 
Iteration: 572589869, states[0] = -9.917874, states[40]= 0.002351
Saving checkpoint... 
Iteration: 585743949, states[0] = -94.876544, states[40]= 0.000000
Saving checkpoint... 
Iteration: 598894736, states[0] = -94.981920, states[40]= 0.000000
Saving checkpoint... 
Iteration: 612044957, states[0] = 13.604193, states[40]= 0.005135
Saving checkpoint... 
Iteration: 625443484, states[0] = -94.993921, states[40]= 0.000000
Saving checkpoint... 
Iteration: 638593197, states[0] = -12.855984, states[40]= 0.001795
Saving checkpoint... 
Iteration: 651739146, states[0] = -94.869817, states[40]= 0.000000
Saving checkpoint... 
Iteration: 664852569, states[0] = -94.965974, states[40]= 0.000000
Saving checkpoint... 
Iteration: 677991421, states[0] = -95.001399, states[40]= 0.000000
Saving checkpoint... 
Iteration: 691141601, states[0] = -61.010231, states[40]= 0.000004
Saving checkpoint... 
Iteration: 704307888, states[0] = -94.940310, states[40]= 0.000000
Saving checkpoint... 
Iteration: 717516437, states[0] = 22.097312, states[40]= 0.015059
Saving checkpoint... 
Iteration: 730423116, states[0] = -94.989491, states[40]= 0.000000
Saving checkpoint... 
Iteration: 743521960, states[0] = 20.969767, states[40]= 0.008561
Saving checkpoint... 
Iteration: 756430560, states[0] = -94.991168, states[40]= 0.000000
Saving checkpoint... 
Iteration: 769334340, states[0] = -94.956780, states[40]= 0.000000
Saving checkpoint... 
Iteration: 782240088, states[0] = -94.871074, states[40]= 0.000000
Saving checkpoint... 
Iteration: 795296630, states[0] = -94.931800, states[40]= 0.000000
Saving checkpoint... 
Iteration: 808200708, states[0] = -94.804012, states[40]= 0.000000
Saving checkpoint... 
Iteration: 821094853, states[0] = -14.369482, states[40]= 0.001556
Saving checkpoint... 
Iteration: 833995727, states[0] = -95.001825, states[40]= 0.000000
Saving checkpoint... 
Iteration: 846923337, states[0] = -94.989472, states[40]= 0.000000
Saving checkpoint... 
Iteration: 860088891, states[0] = -9.089703, states[40]= 0.002523
Saving checkpoint... 
Iteration: 873183109, states[0] = -94.760610, states[40]= 0.000000
Saving checkpoint... 
Iteration: 886246374, states[0] = -94.879616, states[40]= 0.000000
Saving checkpoint... 
Iteration: 900905166, states[0] = -94.984787, states[40]= 0.000000
Saving checkpoint... 
Iteration: 913868916, states[0] = -94.972753, states[40]= 0.000000
Saving checkpoint... 
Iteration: 926770281, states[0] = -94.907725, states[40]= 0.000000
Saving checkpoint... 
Iteration: 939693324, states[0] = -94.788797, states[40]= 0.000000
Saving checkpoint... 
Iteration: 952600169, states[0] = -19.329971, states[40]= 0.001017
Saving checkpoint... 
Iteration: 965497876, states[0] = -95.001998, states[40]= 0.000000
Saving checkpoint... 
Iteration: 978628204, states[0] = -46.349977, states[40]= 0.000049
Saving checkpoint... 
Iteration: 991999522, states[0] = -95.002171, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1005126024, states[0] = -44.093414, states[40]= 0.000070
Saving checkpoint... 
Iteration: 1018253709, states[0] = -94.888909, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1031402478, states[0] = -94.983949, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1046228173, states[0] = -94.853054, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1060925163, states[0] = -94.989767, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1075584656, states[0] = -5.740507, states[40]= 0.003241
Saving checkpoint... 
Iteration: 1090245501, states[0] = -94.878328, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1104911197, states[0] = -94.986295, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1119893830, states[0] = -94.981323, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1134585901, states[0] = -6.682738, states[40]= 0.003040
Saving checkpoint... 
Iteration: 1147983642, states[0] = -95.000114, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1162454771, states[0] = -94.995679, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1175353273, states[0] = -94.965984, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1188225745, states[0] = -94.849070, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1202345847, states[0] = -94.962465, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1215233179, states[0] = -94.860707, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1228126439, states[0] = -44.519570, states[40]= 0.000066
Saving checkpoint... 
Iteration: 1242662872, states[0] = -91.282194, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1257198704, states[0] = -94.799728, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1271379328, states[0] = -94.976420, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1285808003, states[0] = -94.940037, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1298682612, states[0] = -94.758067, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1311727821, states[0] = -94.852332, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1326167441, states[0] = -93.785645, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1339190836, states[0] = -94.783089, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1352064705, states[0] = 5.553747, states[40]= 0.004767
Saving checkpoint... 
Iteration: 1365257058, states[0] = -94.892749, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1378386513, states[0] = -94.978821, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1391497864, states[0] = -95.001737, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1404584251, states[0] = -5.441661, states[40]= 0.003303
Saving checkpoint... 
Iteration: 1417681890, states[0] = -94.754299, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1430766384, states[0] = -94.903288, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1444622038, states[0] = -40.078578, states[40]= 0.000128
Saving checkpoint... 
Iteration: 1458482035, states[0] = -94.999709, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1471588918, states[0] = -9.112019, states[40]= 0.002518
Saving checkpoint... 
Iteration: 1485048702, states[0] = 12.174406, states[40]= 0.005046
Saving checkpoint... 
Iteration: 1498153691, states[0] = -77.526005, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1511195020, states[0] = -29.294420, states[40]= 0.000485
Saving checkpoint... 
Iteration: 1524241775, states[0] = -95.200367, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1537311429, states[0] = -49.245478, states[40]= 0.000033
Saving checkpoint... 
Iteration: 1550579517, states[0] = -95.114178, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1564049628, states[0] = -94.852660, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1577920268, states[0] = -95.199489, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1590996615, states[0] = -33.608726, states[40]= 0.000308
Saving checkpoint... 
Iteration: 1604059914, states[0] = -95.250867, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1617113098, states[0] = -52.649256, states[40]= 0.000019
Saving checkpoint... 
Iteration: 1629614407, states[0] = 22.699250, states[40]= 0.022645
Saving checkpoint... 
Iteration: 1638929261, states[0] = 17.557504, states[40]= 0.007337
Saving checkpoint... 
Iteration: 1653268807, states[0] = -95.261116, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1667812078, states[0] = -51.502430, states[40]= 0.000023
Saving checkpoint... 
Iteration: 1682719150, states[0] = 21.267201, states[40]= 0.012210
Saving checkpoint... 
Iteration: 1697232790, states[0] = -81.301513, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1711780065, states[0] = -95.270778, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1726319142, states[0] = -60.305017, states[40]= 0.000005
Saving checkpoint... 
Iteration: 1740839734, states[0] = -95.231723, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1755373512, states[0] = -9.080403, states[40]= 0.002857
Saving checkpoint... 
Iteration: 1769935123, states[0] = -95.226045, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1784478374, states[0] = -14.081679, states[40]= 0.001807
Saving checkpoint... 
Iteration: 1798998346, states[0] = -95.168687, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1813909509, states[0] = -95.030438, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1828455810, states[0] = -95.025879, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1843018507, states[0] = 21.533309, states[40]= 0.011458
Saving checkpoint... 
Iteration: 1857609854, states[0] = -29.179123, states[40]= 0.000508
Saving checkpoint... 
Iteration: 1872155353, states[0] = -81.437948, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1886539744, states[0] = 15.452994, states[40]= 0.005336
Saving checkpoint... 
Iteration: 1900566879, states[0] = 4.469431, states[40]= 0.004702
Saving checkpoint... 
Iteration: 1914607159, states[0] = -26.023134, states[40]= 0.000661
Saving checkpoint... 
Iteration: 1928658915, states[0] = -86.528131, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1943127667, states[0] = -45.863560, states[40]= 0.000053
Saving checkpoint... 
Iteration: 1957161471, states[0] = -89.910303, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1971216448, states[0] = -94.833264, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1985386100, states[0] = -94.978568, states[40]= 0.000000
Saving checkpoint... 
Iteration: 1999625214, states[0] = -43.278972, states[40]= 0.000079
Saving checkpoint... 
Iteration: 2013639257, states[0] = -58.338730, states[40]= 0.000007
Saving checkpoint... 
Iteration: 2027672783, states[0] = -94.560685, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2041834640, states[0] = -94.956174, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2055901234, states[0] = -94.982955, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2070493937, states[0] = -95.000832, states[40]= 0.000000
Saving checkpoint... 
Iteration: 2084581001, states[0] = -3.180658, states[40]= 0.003750
Saving checkpoint... 
Iteration: 2098655271, states[0] = -80.199111, states[40]= 0.000000
Total time: 4200000.000000
State Variables:
 - v in component membrane (millivolt): -94.877386
 - CaMKt in component CaMK (millimolar): 0.006907
 - cass in component intracellular_ions (millimolar): 0.000074
 - nai in component intracellular_ions (millimolar): 6.612946
 - nass in component intracellular_ions (millimolar): 6.613005
 - ki in component intracellular_ions (millimolar): 145.365935
 - kss in component intracellular_ions (millimolar): 145.365916
 - cansr in component intracellular_ions (millimolar): 1.307390
 - cajsr in component intracellular_ions (millimolar): 1.269472
 - cai in component intracellular_ions (millimolar): 0.000075
 - m in component INa (dimensionless): 0.003627
 - hf in component INa (dimensionless): 0.879576
 - hs in component INa (dimensionless): 0.879571
 - j in component INa (dimensionless): 0.879543
 - hsp in component INa (dimensionless): 0.725030
 - jp in component INa (dimensionless): 0.879523
 - mL in component INaL (dimensionless): 0.000050
 - hL in component INaL (dimensionless): 0.709120
 - hLp in component INaL (dimensionless): 0.450803
 - a in component Ito (dimensionless): 0.000624
 - iF in component Ito (dimensionless): 0.999869
 - iS in component Ito (dimensionless): 0.620467
 - ap in component Ito (dimensionless): 0.000318
 - iFp in component Ito (dimensionless): 0.999869
 - iSp in component Ito (dimensionless): 0.695094
 - d in component ICaL (dimensionless): 0.000000
 - ff in component ICaL (dimensionless): 1.000000
 - fs in component ICaL (dimensionless): 0.934814
 - fcaf in component ICaL (dimensionless): 1.000000
 - fcas in component ICaL (dimensionless): 0.999884
 - jca in component ICaL (dimensionless): 0.999978
 - ffp in component ICaL (dimensionless): 1.000000
 - fcafp in component ICaL (dimensionless): 1.000000
 - nca in component ICaL (dimensionless): 0.001586
 - xrf in component IKr (dimensionless): 0.000003
 - xrs in component IKr (dimensionless): 0.335116
 - xs1 in component IKs (dimensionless): 0.242152
 - xs2 in component IKs (dimensionless): 0.000088
 - xk1 in component IK1 (dimensionless): 0.997344
 - Jrelnp in component ryr (millimolar_per_millisecond): 0.000000
 - Jrelp in component ryr (millimolar_per_millisecond): 0.000000
05:07:32 (2992): called boinc_finish(0)

</stderr_txt>
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